(#35) Enabling Conversations About Long-Acting Injectable Antipsychotics Among HCPs, Patients, and Caregivers With the Long-Acting Injectables: Conversations and Resources for Education (LAI-CARE) Website

Abstract: Background: For people with schizophrenia, long-acting injectable antipsychotics (LAIs) can improve adherence and clinical outcomes versus oral antipsychotics, yet remain underused. Barriers to LAI acceptance include suboptimal treatment introduction, lack of information about available therapeutic options for patients/caregivers, and misconceptions about LAIs. Tools providing guidance for HCPs on effective treatment introduction methods can improve patient acceptance of LAIs, however, convenient, user-friendly tools are lacking. The Long-Acting Injectable Antipsychotics: Conversations and Resources for Education (LAI-CARE) website aims to provide HCP, patient, and caregiver/family member education to enable communication between these groups about LAIs, thereby reducing barriers to LAI acceptance. Methods: LAI-CARE was developed in collaboration with a steering committee of global experts, including a person with lived experience. The site uses interactive features to deliver content based on existing literature and expert opinion. Results: LAI-CARE is an educational web resource providing information about LAIs in 3 modules targeting different audiences. The HCP module focuses on linking treatment goals to patientsí life goals, presenting LAIs as treatment options, addressing patient concerns, LAI features, reintroduction, and common misconceptions associated with LAIs. The modules for people living with schizophrenia and their caregivers include destigmatizing medication nonadherence, nonadherence consequences, enabling treatment plan success, LAI features, HCP discussions, and patient experience. The caregiver module also contains information about supporting their loved one. Conclusions: LAI-CARE is an interactive educational web resource about LAIs for HCPs, people with schizophrenia, and their caregivers, designed to fill identified educational gaps to address underuse of LAIs to improve patient outcomes.Short Description: In people with schizophrenia, long-acting injectable antipsychotics (LAIs) can improve adherence and clinical outcomes compared with oral antipsychotics, yet remain underused. For those seeking information about available therapeutic options, the Long-Acting Injectable Antipsychotics: Conversations and Resources for Education (LAI-CARE) website combines interactive features with evidence-based scientific content. This interactive educational web resource provides information about LAIs for HCPs, people with schizophrenia, and caregivers/family members.Name of Sponsoring Organization(s): Teva Branded Pharmaceutical Products R&D LLC.