Sami Diab, MD, discusses recent updates to the NCCN Clinical Practice Guidelines in Oncology for Breast Cancer, which reinforces the Breast Cancer Index® as the only genomic test predictive of benefit from extended endocrine therapy in...
Sami Diab, MD, discusses recent updates to the NCCN Clinical Practice Guidelines in Oncology for Breast Cancer, which reinforces the Breast Cancer Index® as the only genomic test predictive of benefit from extended endocrine therapy in...
Joseph Sparano, MD, discusses new findings from the TAILORx multimodal AI analysis, which identified that multimodal AI models, particularly the ICM+ model, significantly outperformed traditional models for predicting late distant recurrence...
Joseph Sparano, MD, discusses new findings from the TAILORx multimodal AI analysis, which identified that multimodal AI models, particularly the ICM+ model, significantly outperformed traditional models for predicting late distant recurrence...
Aditya Bardia, MD, discusses results from the phase 3 lidERA trial showing giredestrant significantly improved invasive disease-free survival compared to standard endocrine therapy for patients with ER-positive, HER2-negative early-stage...
Aditya Bardia, MD, discusses results from the phase 3 lidERA trial showing giredestrant significantly improved invasive disease-free survival compared to standard endocrine therapy for patients with ER-positive, HER2-negative early-stage...
Updated results from the EMBER-3 trial show that imlunestrant, alone or with abemaciclib, provides clinically meaningful efficacy and manageable safety among previously treated patients with HR-positive, HER2-negative advanced breast cancer,...
Updated results from the EMBER-3 trial show that imlunestrant, alone or with abemaciclib, provides clinically meaningful efficacy and manageable safety among previously treated patients with HR-positive, HER2-negative advanced breast cancer,...
The FDA has approved a new, simplified once-monthly dosing schedule for amivantamab plus hyaluronidase when administered in combination with lazertinib for the first-line treatment of EGFR-mutated advanced non-small cell lung cancer.
The FDA has approved a new, simplified once-monthly dosing schedule for amivantamab plus hyaluronidase when administered in combination with lazertinib for the first-line treatment of EGFR-mutated advanced non-small cell lung cancer.
Based on data from the phase 1b/2 OrigAMI-4 study, the FDA has granted breakthrough therapy designation to amivantamab plus hyaluronidase for patients with HPV-unrelated recurrent or metastatic head and neck squamous cell carcinoma.
Based on data from the phase 1b/2 OrigAMI-4 study, the FDA has granted breakthrough therapy designation to amivantamab plus hyaluronidase for patients with HPV-unrelated recurrent or metastatic head and neck squamous cell carcinoma.
For clinicians treating breast cancer, staying current has never been more challenging. New trial data, biomarker-driven strategies, and therapeutic options continue to emerge at a rapid pace, yet translating that evidence into confident,...
For clinicians treating breast cancer, staying current has never been more challenging. New trial data, biomarker-driven strategies, and therapeutic options continue to emerge at a rapid pace, yet translating that evidence into confident,...
Results from the phase 1/2 BRUIN study demonstrated that pirtobrutinib showed promising efficacy and tolerable safety in heavily pretreated patients with relapsed or refractory marginal zone lymphoma.
Results from the phase 1/2 BRUIN study demonstrated that pirtobrutinib showed promising efficacy and tolerable safety in heavily pretreated patients with relapsed or refractory marginal zone lymphoma.
Long-term follow-up results from the phase 3 CheckMate 649 trial demonstrate that adding nivolumab to chemotherapy continues to prolong survival in previously untreated patients with non-HER2-positive, unresectable or metastatic...
Long-term follow-up results from the phase 3 CheckMate 649 trial demonstrate that adding nivolumab to chemotherapy continues to prolong survival in previously untreated patients with non-HER2-positive, unresectable or metastatic...
Novel phospholipid drug conjugate iopofosine I 131 demonstrated high and durable response rates among patients with pretreated Waldenström macroglobulinemia, with a manageable hematologic safety profile.
Novel phospholipid drug conjugate iopofosine I 131 demonstrated high and durable response rates among patients with pretreated Waldenström macroglobulinemia, with a manageable hematologic safety profile.
Results from the phase 3 PATINA trial demonstrated that the adding palbociclib to maintenance anti-HER2 and endocrine therapy significantly improved progression-free survival in HR-positive, HER2-positive metastatic breast cancer.
Results from the phase 3 PATINA trial demonstrated that the adding palbociclib to maintenance anti-HER2 and endocrine therapy significantly improved progression-free survival in HR-positive, HER2-positive metastatic breast cancer.
Results from the phase 3 MELATORCH trial demonstrated that first-line toripalimab significantly improved progression-free survival in patients with advanced melanoma, including those with predominantly acral subtype disease.
Results from the phase 3 MELATORCH trial demonstrated that first-line toripalimab significantly improved progression-free survival in patients with advanced melanoma, including those with predominantly acral subtype disease.
On February 10, 2026, the FDA approved pembrolizumab and pembrolizumab and berahyaluronidase alfa-pmph in combination with paclitaxel, with or without bevacizumab, for patients with PD-L1-positive, platinum-resistant epithelial ovarian,...
On February 10, 2026, the FDA approved pembrolizumab and pembrolizumab and berahyaluronidase alfa-pmph in combination with paclitaxel, with or without bevacizumab, for patients with PD-L1-positive, platinum-resistant epithelial ovarian,...
According to results from a retrospective analysis, plasma ctDNA demonstrated strong potential as a biomarker for early detection of metastatic recurrence in patients with muscle-invasive bladder cancer treated with trimodality therapy.
According to results from a retrospective analysis, plasma ctDNA demonstrated strong potential as a biomarker for early detection of metastatic recurrence in patients with muscle-invasive bladder cancer treated with trimodality therapy.