Meeting Materials

Introduction: Chronic wounds frequently harbor asymptomatic bacterial load, which our group monitors with point-of-care fluorescence imaging*.

Introduction: People with diabetes undergoing hemodialysis are ten times more likely to undergo lower extremity amputation than people with diabetes alone. Regular podiatric care is shown to have protective benefits against adverse outcomes in people with diabetes.

Introduction: Sacral decubitus ulcers can be extremely hard to treat.

Introduction: Large Soft Tissue Defects from Necrotizing Soft Tissue InfectionsMethods:Widely Meshed Skin Grafting a 4:1 ratio with autologous skin cell suspension and a dermal matrix used simultaneously to lose large soft tissue defects.Results:No additional surgeries required Outcomes were simi

Introduction: Research of the use of surgical irrigant additives to reduce surgical site infections has been ongoing as surgical site infections can impact quality of outcomes and cost of healthcare.

Introduction: An open-label, interventional clinical trial was conducted at 8 US sites to evaluate a marine-based technology for the treatment of recalcitrant wounds of varying etiologies in a patient population with extensive co-morbidities.

Introduction: Donor site wounds created for autografting are associated with significant morbidity. The Autologous Cell Harvesting Device is used by a clinician at the point of care to prepare an autologous skin cell suspension (ASCS) with a donor-to-treatment site area ratio of 1:80.

Introduction: Surgical wound dehiscence is defined as the separation of “previously approximated wound edges due to a failure of proper wound healing,“ and is estimated to occur in up to 9% of surgical procedures.1,2 Depending upon the severity, incisional dehiscence has a significant impact on m

Introduction: Diabetic foot ulcers (DFUs) continue to challenge wound care practitioners.

Introduction: Lower extremity wounds are particularly challenging and can be attributed to a multitude of etiologies including traumatic accidents, chronic medical conditions, tobacco usage, and oncologic resections.

Introduction: Combination products are increasingly utilized in wound care as innovative biomedical entities that may help to improve patient outcomes.

Introduction: As part of a thorough diabetic foot assessment, screening for limb perfusion to identify early -stage PAD is crucial.

Introduction: Minorities with diabetes have significantly higher rates of diabetic complications, including amputation and death. These higher rates are due to differences in practice patterns, routine preventative care, education, and access to efficacious and affordable treatments.

Introduction: Prone positioning in ARDS can improve ventilation. Its use in the prevention for pressure injury (PI) has been debated. Development of PI has been found in older men, low weight, low Braden score, ICU stay, comorbidities and organ support.

Introduction:

Introduction: Pressure injury with secondary ulceration is a challenge for surgical healing following reconstruction.

Introduction: Flap mobilization is the mainstay of treatment in pressure injury to replace soft tissue loss. Successful outcomes are achieved when there is adequate tissue for transfer. When there is tissue deficiency, procedures may become more challenging, and outcomes may be compromised.

Introduction: The Presence of bacterial colonies that are adherent to the tissue surface are recognized as deterrents to wound healing.  Pressure injury which results in ulceration is often chronic and difficult to heal primarily and may present unique challenges for surgical reconstruction due t

Introduction: Pressure Ulcers (PU) are the most frequent of all chronic wounds and are associated with significant costs as well as patient morbidity. Despite their ubiquity, there are no well-established benchmarks for PU healing upon which clinicians can gauge the efficacy of their care.

Introduction: Diabetic foot ulcers are a severe complication for diabetic patients, significantly impacting patient quality of life and healthcare systems efficiency. These ulcers often lead to hospitalization and amputation.

Introduction: 15-34 % of people with diabetes will experience a foot ulcer in their lifetime. The prevalence of cognitive dysfunction and diabetes is estimated to be between 24-33.7%. This can complicate adherence to self-care behaviors.

Introduction: Skin tears are acute wounds observed especially in the elderly population and conflict zones, caused by mechanical forces as a result of shear, friction, and blunt trauma resulting in separation of skin layers.2 Although the exact prevalence is unknown, evidence suggests that skin t

Introduction: Diabetic foot ulcers (DFU) are a major source of preventable morbidity in adults with diabetes. Consequences of foot ulcers include decline in functional status, infection, hospitalization, lower-extremity amputation, and death.

Introduction: Diabetic foot ulcers (DFUs) pose significant challenges to healthcare systems worldwide, with few effective treatment options recommended by international guidelines.  The role of wound dressings in treating infected DFUs remains unclear.  This clinical trial investigated a first-in

Introduction: Individuals with chronic wounds are highly susceptible to psychosocial stress, particularly loneliness which may negatively impact wound healing.

Introduction: Complex and chronic lower extremity wounds have numerous etiologies and can progress to require eventual amputation.

Introduction: Lower extremity wounds in the United States pose an economic and challenging aspect of post-acute care in populations that undergo Mohs surgical resections and have adverse outcomes that result in open, non-healing sites.  The added cost of these cases for the post-operative failure

Introduction:  NIRS (SnapshotNIR, Kent Imaging LLC, Calgary, Canada) is a non-invasive imaging device that can measure oxygenated and de-oxygenated levels of hemoglobin in the wound and periwound tissues to calculate and create an image of tissue oxygen saturation (STO2).

Introduction: To quantify race, gender, comorbidities, Medicaid status, and compare health outcomes for Medicare-only versus Medicare/Medicaid dual-enrolees who develop a hard-to-heal venous leg ulcer (VLU).Methods:Medicare Limited Data Standard Analytic Hospital Inpatient and Outpatient Departme

Introduction: Near infra-red spectroscopy (NIRS) has been used to evaluate tissue oxygen saturation and perfusion Pulsed Radio Frequency Energy (PRFE) is a noninvasive therapy promoted to decrease tissue inflammation and edema, while enhancing tissue perfusion.

Introduction: Hard-to-heal wounds present a significant healthcare challenge, due to their complex etiology, impact on health-related quality of life, and large economic burden.1 The global prevalence of hard-to-heal wounds has been estimated as 2.21 per 1000 population, and is predicted to incre

Introduction:  The Ankle Brachial Index (ABI) is a widely used diagnostic technique for peripheral artery disease (PAD), which involves measuring the ratio of blood pressure in the ankle to the blood pressure in the arm.

Introduction: Metformin is often used for diabetic patients. It, in general, is also classified as senomorphic.

Introduction: Pediatric bone sarcomas comprise a rare subset of pediatric cancers, with Osteosarcoma (OS) and Ewing sarcoma (ES) accounting for approximately 90%. Patients with metastatic, relapsed, or refractory tumors face poor prognoses.

Introduction: Chronic wounds are a significant healthcare challenge, particularly for the elderly and those with underlying conditions.

Introduction: With the increasing legality and availability of cannabis, it is important to understand the impacts of cannabis on all aspects of dermatologic care. There are several different methods available to ingest marijuana, including inhalation, edible, and topical formulations.

Introduction: Near-infrared spectroscopy (NIRS) with a provocative maneuver of leg elevation has shown promise in point of care detection of PAD in a wound care clinic. The provocative maneuver of leg elevation was added to avoid false positives in patients with CLI.

Introduction: Industry definition of complete wound closure is a wound that has achieved “re-epithelization without drainage or dressing requirements confirmed at two consecutive study visits separated by two weeks”.

Introduction: We examined safety and performance of a new portable NPWT system in the management of patients with traumatic wounds, flaps, grafts and sub-acute wounds.  These patient groups have potential for complications, e.g.

Introduction: Real-world data (RWD) were used to conduct a comparative effectiveness research study (CER) of a Bilayered Living Cellular Construct (BLCC)(a) versus a Fetal Bovine Collagen Matrix (FBCM; Primatrix; Integra, NJ)(b) for the treatment of diabetic foot ulcers (DFUs).Methods:Electronic

Introduction: Clinicians use alternating-pressure air mattresses (APAMs) to prevent pressure injury (PI) by cyclically offloading regions of pressure.

Introduction: Incisional negative pressure wound therapy (iNPWT) reduces the risk of surgical site infections and other wound complications.

Introduction: In healthy adults, nitric oxide (NO) is produced in sufficient amounts but is reduced in elderly, sick, or obese people, which delays wound healing.1,2 Nitric oxide is a highly diffusible, endogenous vasodilator, antimicrobial, and cell signaling molecule.

Introduction: Nearly 2.5% of the United States population is impacted by chronic wounds. These wounds can lead to many complications, including hospitalization, infection, and amputation if not timely diagnosed and properly treated.

Introduction: Surgical wounds pose significant challenges in postoperative care due to their potential for complications and delayed healing.

Introduction: Hard-to-heal wounds are a major challenge to healthcare systems globally1.       The aim of this real-world study was to evaluate the impact of the Wound Hygiene Protocol (WHP), a 4-step (cleanse, debride, refashion, and dress) wound management protocol on hard-to-heal diabetic foot

Introduction: Surgical wound complications impose a heavy burden on health systems.1 Surgical site infections (SSIs) are a leading cause of postoperative morbidity and mortality and are the result of the microbial burden that inhabits skin, mucous membranes, and cavities, and is capable of formin

Introduction: Pressure ulcers cause severe complications that significantly impact healthcare systems and patient quality of life, often leading to hospitalization and death.

Introduction: Diabetic foot ulcers are a severe complication in diabetic patients that significantly impact healthcare systems and patient quality of life, often leading to hospitalization and amputation.

Introduction: Pressure injuries, also known as pressure ulcers or bedsores, occur when prolonged pressure on the skin and underlying tissues reduces blood flow, leading to tissue damage and potential infection.

Introduction: Chronic limb-threatening ischemia (CLTI), an advanced stage of peripheral artery disease (PAD), includes a subset of ‘no-option’ patients for whom conventional surgical and endovascular techniques are not possible, often necessitating amputation.

Introduction: To learn about the experiences of people who seek treatment for hard-to-heal wounds, we distributed a nationwide pilot survey, asking questions about the nature of their wound, how it shapes their daily lives, pathways to receiving care, and experiences with treatment.

Introduction: Vaporous hyperoxia therapy (VHT) is a FDA-510(k) cleared technology  used adjunctively with standard wound care. VHT administers a low-frequency, noncontact, nonthermal ultrasonic mist with topical oxygen therapy.

Introduction: Treatment of chronic non-healing and/or recurrent venous leg ulcers (VLU) represents a significant healthcare problem.

Introduction: Pressure injuries are a common healthcare concern (Isfahani et al., 2024), particularly for patients with limited mobility. For critical care patients this prevalence is 14.3% in the US (Cox et al., 2022).

Introduction: Acute wounds require prompt and effective management to optimize healing outcomes and prevent complications.1 Dressings play a pivotal role in acute wound care by creating an optimal environment conducive to tissue repair.2 While a moist environment is key in wound healing,2 inappro

Introduction: Cellular and tissue-based products (CTPs) are applied to improve wound closure in non-healing wounds. Certain CTPs provide a biological scaffold to facilitate re-epithelialization, while others provide growth factors or cytokines to stimulate natural healing processes.

Introduction: Bacterial infections cause inflammation, tissue damage, and often significant pain for patients with chronic venous leg ulceration. No objective bedside methods exist for validating patient pain, making accurate assessment and management a challenge for wound care clinicians.

Introduction: Burn injuries globally impact millions yearly, causing morbidity, mortality, and tissue loss. Socioeconomic disparities and outdated therapeutic treatments stress the need for innovative and accessible medical approaches.

Introduction: To achieve proper wound healing, wound bed preparation in the early stages of a non-healing wound is vital. Debridement is a part of that wound bed preparation. However, within homecare settings for wound care the resources for debridement are limited.

Introduction: The BaseCAMPs registry aims to meet the urgent need for comprehensive data collection in post-acute care settings concerning the use and outcomes of Cellular, Acellular and Matrix-Like Products (CAMPs).

Introduction: It is estimated that 10 million people worldwide are affected by small fiber neuropathy which involves damage primarily to small unmyelinated C sensory fibers and myelinated alpha delta fibers.

Introduction: Massive localized lymphedema (MLL) is a serious disease that occurs in morbidly obese patients caused by recurrent obstruction in the lymphatic channels, leading to a large pedunculated lymphedematous mass.

Introduction: Many factors perpetuate the chronicity of non-healing wounds. Bacteria, impaired blood flow, and poor oxygenation play a significant role.

Introduction: Dissecting cellulitis of the scalp (DCS) is an inflammatory disease included in the follicular occlusion tetrad, including hidradenitis suppurativa (HS), acne conglobata, and pilonidal disease.

Introduction: Facial defects resulting from Mohs micrographic surgery can be large requiring large reconstructive repairs with a plastic surgeon. These repairs usually require sedation which can pose a greater risk for the patient.

Introduction: Surgical reconstruction of chronic wounds using soft tissue flaps is commonly performed to expedite healing and achieve wound closure.  Several factors have been described that result in a high incidence of failure including reduced tissue perfusion and oxygenation.  Oxygenation is

Introduction: Calcific Uremic Arteriolopathy (Calciphylaxis) usually occurs in patients with end stage renal disease and carries a high morbidity and mortality rate.  The disease is characterized by the calcification of capillaries and arterioles in the dermis and/or subcutaneous adipose tissue. 

Introduction: Tunneling or sinus tracts are complex wounds that often present a challenge to healthcare practitioners. These can extend deep into the subcutaneous tissues or muscle in which due to the size and depth, makes wound management challenging and complicated.

Introduction: Exudate leakage and microbial colonization is a key issue when utilizing compression wraps and total contact casts that are left in place for the full 7 days.Methods:A non-woven polyvinyl alcohol dressing system with silver crystals* in combination with a moisture vapor transport fo

Introduction: A 59 year old male was involved in a sky diving accident which resulted in an ankle fracture requiring an ORIF.  Surgical dehiscence occurred by week one post operative and resulted in a non-healing chronic wound.  After months of surgical management of the wound he was referred to

Introduction: Pyoderma gangrenosum (PG) is a cutaneous ulcerative condition associated with autoimmune disease, exhibiting pathergy in 30% of patients. Trauma exacerbates PG lesions, which may clinicians opt to avoid the essential benefits of debridement.

Introduction: Wounds in vascular patients often pose unique concerns when approaching options for treatment.  Whereas such wounds are inherently acute in nature, wound management in this unique patient population must consider the long-term effects of treatment that will affect the future functio

Introduction: Up to 50% of deep vein thrombosis (DVT) patients develop post-thrombotic syndrome (PTS), a form of chronic venous disease (CVD) that can present with venous leg ulcers (VLUs) and has a debilitating impact on quality-of-life1, 2.

Introduction: Augmented repairs of the Achilles tendon can lead to increased rate of wound complications and infection due to the more extensive approach.

Introduction: Necrotizing foot infections are severe, rapidly progressing conditions that often require aggressive surgical intervention and carry a high risk of morbidity. The incidence of necrotizing fasciitis in diabetics is as high as 40%-60%, with initial mortality rate of 15%-35%.

Introduction: Charcot neuroarthropathy (CN) foot reconstruction is a complex surgical procedure with complication rates as high as 36% overall, with high rates of infection. Appropriate tissue handling is critical to enhance healing and reduce complications.

Introduction: It is well documented that diabetic foot ulcers are a complication that impacts healthcare systems and patient quality of life. Even more problematic are patients with significant co-morbidities and a history of complications. Traditional Standard of

Introduction: A previously healthy 65-yr-old presented with ~3-yr-old posterior lower leg wound sustained while gardening. Debridement at 17 months led to enlargement and increased pain, as did subsequent debridement. Pyoderma gangrenosum (PG) was diagnosed post-biopsy at 29 months.

Introduction: The most common chronic wounds involve venous, arterial, diabetic, and pressure injury etiologies. At times, atypical wounds can present for treatment. With these presentations, it may require a provider to consider different approaches to deal with these problems.

Introduction: Split thickness skin graft sites have documented healing times of two to three weeks and often have increased pain.

Introduction: Patients with peripheral vascular disease usually present with wounds which are difficult to heal per the literature.

Introduction: The Achilles tendon region is noted to be a historically complex area to heal wounds due to its known poor vascular supply. Multiple different theories have been proposed of the exact angiosome supply to this region, most famously by Taylor and Attinger.

Introduction: Combat injuries inflict substantial pain and debilitation, often prolonging return to duty.  Ukrainian health facilities are overwhelmed with a staggering influx of seriously wounded soldiers on a daily basis.

Introduction: A dreaded complication of implanting surgical hardware with a wound dehiscence with exposed hardware. Literature regarding biofilms illustrates the difficult of successfully treating biofilm. Biofilm is difficult to eradicate and reforms quite rapidly after surgical debridement.

Introduction: Spider bites are a reality of living in the Midwest. It is important to differentiate between those with bites, and other disease processes.

Introduction: Platelet-rich plasma (PRP) is an autologous blood-derived product that contains platelet concentrations, cytokines, and platelet-related growth factors. Since the 1980s, the use of PRP to promote healing has gained attention in a multitude of medical fields, including orthopedics, c

Introduction: Open heart surgery is becoming more prevalent with the aging population. As technology improves with significant medical advancements, the contraindications for open heart surgery continue to decrease.

Introduction: Platelet-rich plasma (PRP) is an autologous blood-derived product that contains platelet concentrations, cytokines, and platelet-related growth factors. Since the 1980s, the use of PRP to promote healing has gained attention in a multitude of medical fields, including orthopedics, c

Introduction: Under normal conditions, valves within the venous system direct blood from the superficial into the deep system, which return the blood back towards the heart.

Introduction: Complex lower extremity wounds are often plagued by a combination of soft tissue damage and poor patient protoplasm. Successful limb salvage requires a multimodal approach with the involvement of evidence-based therapies that can facilitate soft tissue repair.

Introduction: At SAWC Spring 2024, the authors reported the results of a retrospective case series in which topical oxygen therapy (cTOT) was used to optimize the wound environment prior to application of cellular, acellular, and matrix-like products (CAMPs).

Introduction: Introduction 

Introduction: Desloughing and cleansing of wounds is a critical step on the pathway to healing of chronic wounds.  While systemic factors can be variable and not controllable, it behooves the wound care clinician to exert as much local control as possible for the wound.

Introduction: Non-healing wounds can represent a significant clinical challenge. Autografting with freshly harvested minced full-thickness skin grafts can enhance healing but can also present technical challenges.

Introduction: Non-healing wounds represent a clinical challenge.

Introduction: Patients with advanced stage hidradenitis suppurativa often experience high morbidity and multifocal disease which presents a significant challenge to their quality of life. There is a need for better solutions for these patients.

Introduction: To evaluate the efficacy of a novel tissue reinforcement using fish skin graft (FSG) to improve the healing of transtibial amputations, decrease the rate of amputation revision, decrease the time to prosthetic fitting, and improve limb durability.Methods: A retrospective review was

 Introduction: Pyoderma Gangrenosum is an uncommon inflammatory condition, and is especially rare as a delayed presentation in the breast region.  It is often triggered by dermal injury such as surgical intervention or trauma, marked by very painful, rapidly advancing ulcers with erythematous vio

Introduction: Wound debridement is a standard of care for wound therapy, however may not be well tolerated by sensate patients.

Introduction: Polylactic acid polymers have been utilized as dermal matrices in wound healing as they can form porous membranes that are non-immunogenic, bioactive, and biodegradable, helping facilitate repair, collagen deposition, angiogenesis, and cellular signaling.

Introduction: Placental-derived tissue products have been widely utilized in wound healing and regeneration as their extracellular matrix (ECM) composition facilitates cell migration, proliferation, angiogenesis, and remodeling.

Introduction: Healing wounds with exposed structures and poorly vascularized, or necrotic tissue is an immense challenge.

Introduction: Almost 80% of VLUs heal by one year using conservative management, however, 6-month recurrence is as high as 50-70% when the underlying etiology is not also addressed.[1][2] In VLUs that fail to heal or that recur, cellular, acellular, and matrix-like products (CAMPs) are highly eff

Introduction: The treatment of hard-to-heal wounds remains a significant clinical challenge. Real-world evidence is essential to understand the effectiveness of products among typical patients and wounds.

Introduction: Chronic venous leg ulcers (VLUs) can be challenging to heal and are often fraught with higher rates of cellulitis and subsequent hospitalizations (1).

Introduction: Tissue scaffolds are a wound care option to complement other existing techniques.

Introduction: Third degree burns represent a significant risk for infection and morbidity for affected patients. Hence, treatment is focused on preventing deep infection, limiting fluid loss, ameliorating pain, as well as promoting prompt tissue regeneration.

Introduction: Chronic Pressure Ulcers, despite standard care, often are stalled in their healing due to unaddressed chronic biofilm. Resistant to antimicrobial agents, bacterial biofilms engender a chronic inflammatory response within the wound.

Introduction: While reticulated open cell foam (ROCF) is a well-established dressing for negative pressure wound therapy (NPWT), granulation tissue ingrowth can occur if the dressing is left in place longer than 72 hours, potentially causing wound bed disruption, bleeding, and pain upon dressing

Introduction: Necrotizing soft tissue infection (NSTI) targets the skin, subcutaneous tissue, or muscle and can rapidly spread to adjacent tissue planes due to poor blood supply.1 NSTIs are classified into three different bacteriologic classes.

IIntroduction: n 2020, the burden of chronic wounds impacted the quality of life of approximately 2.5% of the United States population and continues to climb(1).

Introduction: Several veterans deal with lasting effects of their military service long after discharge, and “their wounds from war are daily facts of life.”1 That was the story of the veteran described here, who dealt with a foot wound from a combat injury for 53 years before enrolling in an ong

Introduction: Once a wound develops, patients often present to community-based health care providers for wound management. However, these providers may not be specialized in wound care.

Introduction: Degloving injuries are traumatic events in which the skin and tissue are torn away from underlying structures.

Introduction: Neglected Lisfranc injuries in diabetic patients with a history of smoking pose significant challenges in surgical management, often resulting in complications such as surgical dehiscence.

Introduction: Diabetic foot ulcers to the plantar forefoot can be challenging to heal and often require surgical intervention. This case study aims to evaluate the use of acellular fragmented fish skin graft as an interpositional graft in first metatarsal joint arthroplastyMethods:

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Introduction: Treatment of complex pressure wounds especially those with tunnelling and undermining can be challenging. In many cases, operative debridement and complex closure with a flap is required to achieve a durable closure.

Introduction: The purpose of this study is to demonstrate the complexities of wound healing efforts with patients who have a history of chronic pedal unilateral ulcerations caused by osteomyelitis localized to the foot secondary to diabetes mellitus with lymphedema, and concomitant acute chemothe

Introduction: Chronic wounds often fail to heal due to various factors, including poor tissue oxygenation. Improving tissue oxygenation has been a central tenet of promoting wound healing since the early 1900’s.

Introduction: Diabetic patients pose complex extrinsic and intrinsic challenges that require a multifactorial approach to wound healing using more advanced technologies including human placental membrane tissues.

Introduction: Negative pressure wound therapy (NPWT) typically requires dressing changes every 2 to 3 days. A novel dressing has been developed that incorporates a fenestrated, non-adherent layer and negative pressure drape into the dressing design allowing for up to seven days of wear.

Introduction: The problem that was addressed by our wound clinic was that we had hard to heal chronic wounds that had been present often times for greater than 6 months in patients with diabetes.

Introduction: A 78 year-old male patient presented with dry pre-gangrenous toes wounds bilaterally that would not heal over the past 6 months, in spite of oral anticoagulant, orthotics and topical treatments.  The patient is a chronic smoker with a history of hypertension and had 2 major surgerie

Introduction:

Introduction: Necrotizing fasciitis is a life-threatening condition with rapid progression that is known to potentiate risk for limb amputation.

Introduction: Plantar hallux ulcerations are known to be a difficult ulceration to heal due to weightbearing requirements and foot biomechanics.  They often will go on to nonhealing despite offloading.  The purpose of the case series was to evaluate a novel way to heal plantar hallux ulcerations

Introduction: Arterial insufficiency has been discussed as a relative contraindication by some physicians for applying skin substitutes in diabetic patients.  The purpose of this abstract is to evaluate the validity of using fish skin grafting (FSG) in diabetic wounds with known PAD and elevated

Introduction: In the United States (US), approximately 37.3 million people have diabetes. Complications may include development of ulcers that can be life threatening if not diagnosed timely, promptly treated, and managed properly.

Introduction: Wound healing complications in patients that underwent an Achilles tendon surgery is associated with postoperative morbidity. These complications following Achilles tendon surgery are due to the fragility and limited vascularization of the skin.

Introduction: Surgical wound dehiscence is a separation of wound edges due to a failure of proper healing that typically starts at 5 to 8 days following surgery.

Introduction:  Recalcitrant foot ulcers are increasing in prevalence and often exhaust conventional conservative measures. The risk of a diabetic with a foot ulceration to proceed to an amputation is between 14% and 24%. Mortality after diabetes-related amputation exceeds 70% at 5 years.

Introduction: Venous leg ulcers (VLU), account for 70% of all leg ulcers, occurring in 1-2% of the general population and in 4% of people 65 years of age and older.1.

Introduction: Chronic wounds in the home care setting can be resource-intensive and the complexity of the wound is often compounded by the presence of multiple comorbidities.1 External factors like decreases in Medicare reimbursement and lack of wound care experts in the home care setting often m

Introduction: The BIOMES framework (Blood Flow, Infection Control, Off-Loading, control of Metabolic/co-morbidities, management of Exudate/moisture/bioburden, and understanding of the patient’s Social/economic barriers) helps identify early signs of chronicity in wounds.

Introduction: Trauma to the extremities represents one of the most common injury forms leading to large, full thickness soft tissue loss. Achieving closure after extensive debridement of necrotic tissue can be challenging, especially in patients with multiple co-morbidities.

Introduction: 57-year-old Caucasian male with a past medical history of RCA STEMI and reduced EF%, admitted to the hospital with diagnosed necrotizing fasciitis infection involving his perineum, scrotum, pubis, and right flank.

Introduction: Lower extremity wounds often pose unique treatment challenges to both clinicians and patients.

Introduction: The application of negative pressure wound therapy to support healing of lower extremity wounds is well-documented.1 A recently available multilayer peel and place dressing (MPPD) incorporates a perforated non-adherent layer, reticulated open cell foam dressing, and a hybrid acrylic

Introduction: Negative pressure wound therapy (NPWT) has been well documented in the management of a variety of wound types. Traditionally, negative pressure is delivered via foam dressings directly to the wound bed.

Introduction: Current solutions for managing recalcitrant foot wounds using advanced skin substitutes present several disadvantages including risks of rejection, disease transmission, and cultural prohibitions from mammalian-sourced materials.

 Introduction: Fish skin graft (FSG) is a xenograft derived from Atlantic cod that augments wound healing1. This case evaluates FSG* in a patient with non healing diabetic foot ulcer (DFU) which had not responded to conservative wound care.

 Introduction: Fish skin graft (FSG) is a xenograft derived from Atlantic cod that augments wound healing1. This case evaluates FSG* in a patient with non healing diabetic foot ulcers (DFU) which had not responded to conservative wound care.

Introduction: Fish skin graft (FSG) is a xenograft derived from Atlantic cod that augments wound healing1. This case evaluates FSG* in a patient with nonhealing diabetic foot ulcers (DFU) which had not responded to conservative wound care.

Introduction:  Fish skin graft (FSG) is a xenograft derived from Atlantic cod that augments wound healing1. This case evaluates FSG* in a patient with non healing diabetic foot ulcer (DFU) which had not responded to conservative wound care.

Introduction: Calciphylaxis, or calcific uremic arteriolopathy, presents a significant treatment challenge due toits severe pain, chronic wounds, and high mortality.

Introduction: Due to the inflexibility of scalp skin, Mohs Micrographic Surgical resection of skin cancers of the scalp can create difficult wounds due to exposure of the bone of the calvarium. Large wounds in scalp skin can limit the feasibility of flap reconstruction.

Introduction: Wound healing can be a challenging and complex problem for some patients.  In persistent non-healing wounds, the healing process is often confounded by colonizing bacteria and subsequent biofilm formation.

Introduction: Although a primary closure of wound via a rotational skin flap is ideal in terms of conserving time and getting an individual back to their daily life earlier, it comes with the downside of increased morbidity.

Introduction: Heel wounds secondary to osteomyelitis present a unique challenge to a surgeon.

Introduction: Negligence in extended care facilities is a critical issue that can lead to severe harm or even death for residents. Studies have shown that these lapses lead to increased rates of infections, falls, and medication errors among residents amongst many other complications (1).

Introduction: Healing tunneling wounds is particularly challenging due to their complex structure and the difficulty in accessing the entire wound area for treatment.

Introduction: Venous stasis leg ulcers (VLU) affect 1-2% of the general population and approximately 4 percent of patients more than 65 years old.1 After healing, VLUs have a recurrence rate of 22% within 3 months, 57% within 12 months, and 78% within 3 years.1 Wound care is a medical necessity i

Introduction: Bone and tendons have poorer blood supply compared to skin and muscle tissues (1). This hinders the delivery of oxygen and nutrients crucial for healing, making the exposed tissues more susceptible to infection and tissue death (2).

Introduction: Despite medical advancements, the incidence of lower extremity amputations in the US has not improved.1 Amputation is associated with increased mortality and should be avoided, if possible, by employing technology to facilitate wound healing and limb salvage, such as autologous skin

Introduction: Hidradenitis Suppurativa is an inflammatory condition of pilosebaceous units characterized by recurrent, painful nodules, purulent abscesses, and chronic sinus tracts.

Introduction: A borate-based bioactive glass matrix (BBBGM)* has demonstrated promise in healing hard-to-heal wounds,1–3 potentially reducing treatment costs. We compare dressing treatment costs prior to BBBGM vs.

Introduction: Critical limb ischemia (CLI) is a severe form of peripheral artery disease (PAD) characterized by significantly reduced blood flow to the extremities, usually the legs.

Introduction: Peripheral arterial disease (PAD) affects over 200 million people globally, including 8.5 million in the United States, with annual US management costs reaching $22 billion.

Introduction: Podiatric wound management may be complicated by patient comorbidities and irregular wound geometries e.g. tunneling or undermining. In complex podiatric wound presentations, skin substitutes are utilized to support the SOC toward wound closure and limb salvage.

Introduction: The fat pad on the bottom of the foot serves as a shock absorber, protecting underlying tissue during weight-bearing activities. Atrophy or displacement of this fat pad increases plantar pressure on the bones, leading to pain, disability, and possible ulcerations.

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Introduction: Venous leg ulcers (VLUs) affect 1-3% of the US population, with healthcare costs estimated at $32 billion annually1.  VLUs are characterized by delayed healing and high recurrence rates, with only 60% closing by 12 weeks and 75% reappearing within 3 weeks 2.

Introduction: Calciphylaxis, also known as calcific uremic arteriolopathy, is a rare disease most often found in patients with end-stage renal disease. Cutaneous arteriolar calcification and subsequent tissue ischemia and infarction cause painful skin lesions and necrotic wounds.

Introduction: Traumatic injury is one of the major risks associated with working in the United States Military Special Operations Division. Gunshot wounds, improvised explosive devices, and blunt force trauma are just a few of the methods of injury.

Introduction: The American Board of Plastic Surgery (ABPS) is the legitimate certifying board for plastic surgeons for legitimate plastic surgery training. This training includes the full spectrum of cosmetic surgery.

Introduction: Mohs surgery is a tissue-sparing dermatologic surgery utilized to treat skin cancers. Reconstruction of soft tissue defects following Mohs surgery can be challenging on the lower extremities due to limited adjacent tissue laxity and higher rates of post-operative infections[1].

Introduction: Pressure ulcers are a significant healthcare challenge, particularly for individuals with limited mobility or impaired circulation.

Introduction: Like humans, animals often develop wounds from falls, trauma, and surgery that require wound care.

Introduction: Anal fistula is an infected tunnel between the skin and anus, the muscular opening end of digestive tract. Most anal fistulas are result of infection in anal gland spreading to skin. Symptoms: pain, swelling, discharge of blood/pus from anus.  Surgery usually needed.

Introduction: Pilonidal cysts (PCs), cysts that develop in the sacrococcygeal region, are common and frequently impact healthy young males.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory disease that manifests with abscesses and sinuses formations. The management of HS is multidisciplinary including surgical resection and skin reconstruction in advanced and chronic stages.

Introduction: A lymphocele is an atypical collection of lymphatic fluid that develops into anatomic compartments.  Due to the location and size of these lymphoceles, surgical intervention is indicated in such cases to provide symptoms relief of pain and debilitation.

Suppurative myositis a rare type of autoimmune disease that inflames and weakens muscle fibers.  In myositis, the immune system attacks healthy muscle tissue, which results in inflammation, swelling, pain, and  weakness. An acute inflammation characterized by neutrophil-rich infiltrates.

Introduction: Seromas are reported in nearly all cases of hernia repair after radiologic imaging. Clinically symptomatic seromas are reported in up to 12.5% of patients following incisional hernia repairs.

Introduction: Venous Leg Ulcers (VLUs) are difficult to treat due to the challenge of edema and the result of chronic venous insufficiency (CVI) and lymphedema. Patients report a decreased quality of life due to pain, exudate management, and odor control issues.

Introduction: Rising populations in rural and remote areas face significant challenges in accessing healthcare, particularly for chronic and slow-healing wounds.

Introduction: Wounds in patients with significant venous insufficiency and chronic stasis dermatitis may present complex challenges, often exacerbated by persistent bio burden.

Introduction: Patients with lymphedema are at increased risk for the development of wounds due to the increased diffusion difference between their skin and circulatory system.

Introduction: In the United States, chronic wounds affect more than 6.5 million people annually, costing more than $25 billion, with a mean cost of $23,755 among neurosurgery patients.

Introduction: 62 year old female who presented to the emergency department with a left leg ulceration measuring 3.0 x 2.8 x 0.6 cm which had been present for 2.5 months.

Introduction: Lower extremity limb salvage is a cornerstone of podiatry, which is often fraught with complications due to the complexity of the diabetic foot and often with vascular compromise.  Foot and ankle surgeons perform reconstructive flaps as part of their armamentarium to treat soft tiss

Introduction: Chronic wounds typically arise secondarily to comorbidities such as diabetes mellitus and cardiovascular conditions.  Although many treatment modalities exist for persistent wounds, product efficacy data is often from limited study designs.  Here, we investigated how a bioactive gla

Introduction: A case report was compiled for a 66 y.o. male with past medical history of factor V Leyden mutation, essential hypertension, chronic lymphedema, obesity, DVT of the lower extremity, diabetic ulcer of the left midfoot, severe calcific aortic valve stenosis, diabetes mellitus type 2,

Introduction: A case report was compiled for a complicated patient who had multiple co-morbidities, significant varus deformity, complex wound and at high risk for amputation of the affected limb.

Introduction: This is a case of using Fish Skin Graft (FSG) on a large open wound complicated by olecranon bursitis.  The patient is a right handed 87 yr old male avid fisherman with history of facial/esophageal metastatic squamous cell cancer (SCC).  

Introduction: This is a 66 yr old female who is a noncompliant diabetic and smoker with PAOD, PVD, HTN, and history of MI x 2 with PTCA and stent placements.  This patient presented to the ER in October with cellulitis of her right foot due to a gangrenous right great toe.  She had an open wound

Introduction: Squamous cell carcinoma (SCC) is the second most prevalent malignant skin cancer.  The head and neck is the most common location and generally older patients are affected. In wounds with exposed bone, there are limited reconstructive options.

Introduction: Fluorescence guided wound care allows clinicians to visualize bacteria of the wound in real-time, is effective across skin tones, and in wounds where subjective clinical signs and symptoms of infection are undetected despite high bacterial loads.

Introduction: Cutaneous metastasis from internal malignancies is rare, and its presentation as wounds is even less common. This study presents four cases of patients initially presenting with wounds, later diagnosed as cutaneous metastases from various carcinomas.

Introduction: Pilonidal cysts and the resultant post-surgical wounds often present unique treatment challenges for both clinicians and patients.

Introduction: 68 year old male who presented on January 18, 2024 with shortness of breath. He has a positive history of tobacco and substance abuse. The patient has been intermittently homeless.

Introduction: Health equity is the state in which everyone has a fair and just opportunity to attain their highest level of health.1

Introduction: The use of pure hypochlorous (pHA) acid based cleansers to cleanse wounds is well documented, and evidence based.

Introduction: Two well understood and documented components of wound bed preparation (WBP) include removal of devitalized tissue and management of surface bioburden.

Introduction:  Vibrio Vulnificus is an opportunistic gram-negative bacterial pathogen that is found in  warm low-salinity waters. V. vulnificus wounds are increasing in prevalence due to the rise in temperatures of the sea water. (3) 

Introduction:

Introduction: Diabetic foot ulcers (DFUs) represent a significant human and economic burden to the healthcare system. Bacterial infections amplify the cost-to-treat, and thus proactive infection management lessens this burden.

Introduction: Enhancing Wound Bed Preparation (WBP), (Schultz) (Sibbald) guides evidence based bedside leg ulcer management advancements: textile compression, Aristotle 365 BCE, moist wound care, aggressive debridement, and recently Negative Pressure Wound Therapy.

Introduction: Below knee amputations are a major cause for morbidity and mortality in the diabetic population. The five-year mortality rate after a below knee amputation is 40-82% with a 30-day mortality rate of 17%.

Introduction: We’ve reported dramatic outcomes using an inexpensive warp knitted compression stockinet* to control edema since 2009 (Sibbald) (Ehmann 2020).

Introduction:

Introduction: Pilondial disease complicated by chronic inflammatory, fibrotic, and tunneled features represent a difficult clinical challenge.  These wounds are often refractory to both medical and surgical management and have underlying heavy microbial colonization.  Plastic surgical reconstruct

Introduction: Friction burns (FB), commonly called road rash, are superficial injuries frequently associated with sports activities and road accidents. FB are caused when the skin rubs into another surface and the friction produces a painful abrasion.

Introduction: Chronic pressure injuries are known to place patients at high risk for poor health outcomes, including death and disability.1 For example, expedited wound closure is imperative because secondary infections are a concern and deleteriously impact the patients' acute and long-term

Introduction: Pressure injuries (PIs) present a significant challenge for both patients and healthcare providers, leading to pain and discomfort, complications, increased healthcare costs, and the potential for litigation against sites of service.

Introduction: A 71- year-old male presented to the wound care center for non-healing surgical wound of his right lower leg and foot for greater than one year.

Introduction: Chronic foot ulcers are a severe complication for patients with diabetes, significantly impacting quality of life, increasing financial burden, and leading to non-traumatic amputations in the United States.

Introduction: Statistics are over whelming as are our clinical experiences in regard to hospital acquired tissue injuries- the very fact that they are so frequent in the year 2024 is difficult to understand.

Introduction: Second-degree burns, are a type of burn that destroys your epidermis and dermis layers of you skin. This type of burn is serious and requires medical treatment.

Introduction: Radiation recall dermatitis (RRD) is a rare inflammatory skin reaction at previously irradiatedsites, often triggered by chemotherapy drugs.

Introduction: Chronic venous insufficiency (CVI) is prevalent among the elderly population, with a documented prevalence rate of 1.69%.1 This condition can result in serious complications, including venous leg ulcers (VLU).2 VLU affects around 2.2 million Americans annually.3 VLU episodes can per

Introduction: surgery is a tissue-sparing dermatologic surgery utilized for the treatment of nonmelanomaskin cancers.

Introduction: A Topical Desiccating Agent (TDA) based on methanesulfonic acid (MSA) and dimethyl sulfoxide (DMSO) has proven to be an effective biofilm- and necrosis-removing chemical debridement option.

Introduction: Soft silicone multilayer foam dressings (SSMFD) are indicated for the treatment of acute and chronic wounds including pressure ulcers, leg ulcers, diabetic foot ulcers, surgical wounds, first and second degree burns, donor sites, skin tears, and fungating ulcers.

Introduction: Hard-to-heal wounds often exhibit reduced tissue oxygen levels (Jain et al., 2006). Hyperbaric Oxygen Therapy (HBOT) has demonstrated the ability to enhance oxygen supply to such wounds, promoting healing.

Introduction: Native Americans have a significantly higher rate of health disparities than other populations in America.

Introduction: In a PT-driven wound clinic without physician oversight, it is important to clinically recognize chronic osteomyelitis in a diabetic foot wound to expedite early and appropriate treatment.

Introduction:Pressure injury prevention (PI/PIP) protocols trigger use of a range of interventions and products based upon individual PI risk1 . Hospitals commonly develop multidisciplinary groups called

Introduction: Topical Oxygen Therapy (TOT) has been used clinically for over 50 years with many case series and open label cohort studies supporting its role in wound care.

Introduction: In recent years, xylazine, an alpha-adrenergic agonist, has increasingly contaminated the opioid supply in many areas of the United States.2 Used to extend the subjective effects of opioids, xylazine is implicated in difficult-to-manage drug overdoses, use disorders, and, in particu

Introduction: While there is an abundance of literature that is descriptive of pressure injury risk in the adult patient population, there is much less data on pressure injuries in children.

Introduction:

Introduction: The goal of the project was to reduce hospital acquired pressure injuries that fall under the PSI-3 criteria set by the Agency for Healthcare Research and Quality in a 500 bed, level 2 trauma, tertiary care hospital.

Introduction: Wound Care Plus, LLC (WCP) is a mobile wound care advanced practice provider dedicated to advancing wound care for underserved patients across various care settings. Our commitment extends to overcoming challenges related to diagnostic access.

Introduction: With an increase in patients requiring wound care, development of new wound care options has also intensified.

Introduction: Early identification and prevention of Pressure Injuries (PIs) pose significant challenges in hospital settings.

Introduction: Post-operative surgical site complications (SSCs) represent a significant burden to healthcare systems globally and pose many challenges for patients undergoing Cardiovascular procedure1-3.

Introduction: Total joint arthroplasty (TJA) can be associated with surgical site complications (SSCs), such as the development of surgical site infections (SSIs) and prolonged postoperative drainage, resulting in significantly increased length of stay (LOS) and healthcare costs1,2,3.

Introduction: Background: Professional wound and ostomy care is necessary in to enhance outcomes and quality of life for patients who require it. Newly certified registered nurses (RNs) often have little hands-on experience with the important skills required for wound and ostomy care.

Introduction: Chronic wounds are becoming an increasing economic and societal burden, growing with our aging population and the prevalence of diabetes mellitus, obesity, and peripheral vascular disease.  Several recent studies show that a multidisciplinary team in a wound center can better addres

Introduction: The purpose of this study was to examine the cost-effectiveness of placental allografts as a nonoperative surrogate to autologous tissue-based methods of defect reconstruction on the face, head, and dorsal hand following Mohs micrographic surgery (MMS).Methods:This study was a 5-yea

Introduction: Tissue breakdown risk can be mitigated through suitable cushioning materials to disperse surface and internal tissue stresses.

Introduction: Non-healing wounds affect 10.5 million U.S. Medicare beneficiaries (Sen, 2023).

Introduction: Inflammation is a complex physiological process that serves as a protective response to infection, tissue injury, or stress.

Introduction: Limb salvage is critical in the care of patients suffering from chronic limb threatening ischemia (CLTI). Nevertheless, a substantial proportion of patients, particularly those considered ‘no-option’, eventually undergo major lower extremity amputation (LEA).

Introduction: Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both, often leading to complications such as diabetic foot ulcers (DFUs).

Introduction:

Introduction: Annually, 10.5 million Americans suffer from chronic wounds, with associated costs projected to exceed 30 billion USD by 2030.

Introduction: Pressure injuries impose a significant financial burden on healthcare facilities while also compromising patient well-being (Padula et al., 2019). These injuries often lead to extended hospital stays and increased utilization of healthcare services.

Introduction: Diabetic patients are prone to developing chronic wounds due to numerous underlying causes, some of those including being vulnerable to infections, dysregulated growth factor levels, and altered MMP expression.

Introduction: Effective wound management is essential for promoting healing, preventing complications, and improving patient outcomes.

Introduction: Moisture balance of the wound bed is important in wound healing.1  An ex vivo porcine wound model was used to assess the impact of oxygen flow during application of continuous Topical Oxygen Therapy (cTOT) on the moisture levels at the wound bed.Methods:Simulated wounds were created

Introduction: Moisture balance of the wound bed is important in wound healing.1  To maintain this balance it is important that excess exudate is absorbed away from the wound unimpeded into an appropriate absorptive dressing.

<p>Introduction: A compromised epidermal barrier underlies incontinence-associated dermatitis (IAD).

Introduction:

Introduction: Wound re-epithelialization is marked by the formation of a new epithelial layer that re-establishes the barrier between a wound and the environment allowing for successful wound closure.

Introduction: Chronic wounds have a significant impact on a substantial number of Americans today. The etiology of these wounds is often multifactorial, not fully understood, and further complicates the healing process.

Introduction: Biofilms represent a significant impediment to wound repair and are nearly ubiquitous in all chronic wounds.

Introduction: While Silver is widely regarded as an effective antimicrobial agent it can be cytotoxic to fibroblast and keratinocytes, and the reported antibacterial effects of silver are based on in-vitro studies rather than the more complex in-vivo environment.

Introduction: It is well known that pH controlled, mildly acidic pure Hypochlorous Acid (pHA) based cleansers produce visibly clean wounds, that also can be shown to have lower bioburden as measured by punch biopsies.

Introduction: Various processing techniques are utilized to manufacture placental allografts, including cryopreservation, dehydration, lyophilization, and hypothermic storage. Processing is known to impact native tissue composition and characteristics, compared to native tissues.

Introduction: The clinical use of pure hypochlorous acid(pHA/HOCl)-based wound cleansers has gained widespread adoption for a number of reasons, such as their mildly acidic nature, they exhibit rapid and broad-spectrum antimicrobial(AM) properties, and their clinically proven ability to lower the

Introduction: Decellularized extracellular matrix (ECM) medical devices can facilitate healing of hard-to-heal wounds by acting as a scaffold.

Introduction:

Introduction: Aplicor 3D is a novel FDA-cleared 3D printer that uses autologous human adipose to create patient-specific wound coverings.

Introduction: Hard-to-heal wounds pose a significant clinical challenge, resulting in poor patient quality of life and substantial economic burden.

Introduction: The immune system is central to progressing an injury through the wound healing cascade.

Introduction: The interplay between fibroblasts and extracellular matrix (ECM) proteins is an important factor in the normal wound healing cascade.

Introduction: Placenta-based scaffolds are known for their regenerative potential in various clinical applications, often requiring terminal sterilization to ensure safety. The choice of sterilization method can impact the biological activity and clinical performance of these products.

Introduction: Collagen-based wound matrices are widely used for treating acute and chronic wounds due to their role in wound management. The addition of an antimicrobial to these matrices can also prevent bacterial contamination of the material and act as an antimicrobial barrier to wounds.

Introduction: Chronic wound healing remains a persistent medical challenge, prompting the exploration of innovative approaches for making advanced wound dressings.  One such technique is 3D bioprinting, which is happening in the US with the Aplicor 3D system that uses autologous adipose tissue to

Introduction: The presence of microorganisms, development of biofilm, and local infection play a significant role in the pathogenesis of hard-to-heal wounds.

Introduction: Povidone polymer stabilizes and improves the use of iodine to reduce wound infections, but iodine is a weak oxidizer and not biocompatible.  A halohydantoin-based polymer exists that stabilizes chlorine, and the efficacy for wound infection control of this stronger oxidizing agent w

Introduction: Amniotic membrane is a promising biomaterial for regenerative medicine, with numerous placental membrane products available on the market for various applications.  A standardized method for Tensile testing using an Instron 5544 has been established (1).

Introduction: Biofilms are a common problem in chronic wounds. A thermo-reversible antimicrobial hydrogel (TRH) containing polyhexanide (PHMB) has previously been shown to be effective against of biofilms when tested using in vitro models.

Introduction: Decellularized extracellular matrix (ECM) medical devices can facilitate healing of hard-to-heal wounds by acting as a scaffold.

Introduction: Diabetic ulcers are a significant complication of diabetes mellitus, commonly attributed to peripheral neuropathy and associated vascular insufficiencies.

Introduction: Colonization of pathogens in wounds significantly inhibits wound healing and is a major factor in the failure of wounds treated with skin grafts and skin substitutes.  Synthetic materials such as bioactive glass are known to have antimicrobial effects and are becoming commercially r

Introduction: It has been researched and well documented that placental tissue has a plethora of growth factors present. Many of these factors are beneficial when it comes to wound treatment as they facilitate an optimal wound environment upon placement of the graft.

Introduction: It is commonly accepted that bacteria found within hard-to-heal wounds exist as surface-associated or aggregated communities, often comprising multiple species.1,2 This polymicrobial nature increases virulence and tolerance to antimicrobial agents.3,4 We evaluated antimicrobial dres

Introduction: In vitro assessment of silver-containing gelling fiber dressings against wound surface-associated antibiotic-resistant pathogensMethods:Four silver-containing dressings were evaluated: carboxymethylcellulose (CMC) dressing containing ionic silver, ethylenediaminetetraacetic acid (ED

Introduction: Non-healing wounds affect over 10.5 million US patients, with healthcare costs estimated at $28-$97 billion1. Multidrug-resistant organisms (MDROs) significantly complicate acute and chronic wounds2.

Introduction: A revolutionary advance in personalized wound care uses a patient's own adipose tissue as the foundation for creating custom-designed wound tissue grafts with the Aplicor 3D printing system.

Introduction: Negative pressure wound therapy (NPWT)* with reticulated open cell foam (ROCF)^ has evolved the practice of wound care. To date, ROCF has not been utilized as an extended wear dressing due to the potential for tissue ingrowth that may occur if left in place for >72 hours.

Introduction: Patients with Pyoderma gangrenosum (PG) can feel like they are walking through a dark tunnel. They need our help to reach the light and close the PG wounds. PG is a painful, inflammatory, ulcerative skin disorder affecting 5.8 people per 100,000 adults.

Introduction: Wound healing progression consists of specific cellular processes that may not be visible until clinical symptoms are observed.  A visual assessment may not provide early awareness of wound deterioration, thus delaying specific interventions and progression toward closure.

Introduction: Hidradenitis suppurativa (HS), a chronic, debilitating, and relapsing inflammatory disease of skin, is extremely challenging to manage. Specialized providers are few, and scattered, PCPs do not routinely treat HS, and a comprehensive treatment model is rare.

Introduction: Diabetes mellitus is a chronic disease that continues to increase in prevalence globally. Diabetics can develop foot-related issues including infections, ulcerations, and gangrene, which can result in amputation or death.

Introduction: Chronic wounds affect millions of US people and burden patients and healthcare systems.

Introduction: Near Infrared Spectroscopy* (NIRS) is a non-invasive imaging device that measures oxygenated and deoxygenated hemoglobin in the wound and periwound tissues to assess the tissue oxygenation saturation percentage two to three millimeters below the epidermal surface.  Tissue evaluation

Introduction: Traditional chart review in wound care research is increasingly challenged by a growing volume of patient data and extensive variables impacting wound outcomes.

Introduction: Fifty percent of acute care support surfaces are compromised within 3.8 years with an increase in failure odds of 67.6% with each additional year of age.1 Compromised surfaces have a 5.83 times greater risk for cross-contamination than that of controls.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition marked by the formation of painful, purulent lesions in intertriginous regions, which can lead to the development of sinus tracts and fibrotic scarring. Diagnosis of HS relies primarily on clinical evaluation.

Introduction: Negative pressure wound therapy (NPWT) using a polyurethane, reticulated open-cell foam (ROCF) dressing has been employed for managing diverse wound types. While NPWT’s therapeutic benefits are well established, ROCF dressing application can create obstacles for therapy.

Introduction: An estimated 3 million patients per year are treated for pressure injuries (PIs) in the United States with cost approaching $17.8 billion.1 PIs are the most prevalent in intensive care units (ICUs) with incidence of 8%-40% resulting in increased length of stay, higher mortality rate

Introduction: For the Wound and Lymphedema communities, a Wearable Pressure sensor (WPS) -- to evaluate dressings and teach practitioners best wrapping techniques -- could be transformational.  To adopt such an innovation, the proposed WPS must be clinically accurate.  The goal of this poster is

Introduction: It is usually unclear exactly how much pressure a dressing applies to the leg, and if that pressure is uniform. The goal of this study was to compare two compression dressing types in terms of pressure they are applying from toe to knee. 

Introduction: World Health Organization growth charts1 utilize Centile-based curves to track age-related growth dynamics. Identifying values outside of specific ranges indicates the need for further investigation or intervention.

Introduction: Chronic wounds may take 12 or more weeks to close1. These wounds cost medical systems billions of dollars worldwide2. Accurate and early detection of delayed wound healing may lead to better patient outcomes and lower treatment costs.

Introduction: Venous leg ulcers (VLU) are the most common type of chronic wound accounting for over 70 percent of lower extremity chronic wounds.1-2 Many clinicians describe chronic wounds as a failure to improve surface area dimensions by 50% in one month.3 The 5-year mortality rate for patients

Introduction: Accurate assessment and documentation of wound tissue composition are crucial to monitoring wound healing progress or deterioration.

Introduction: With a recent increase in reported wounds, addressing barriers to wound healing has become crucial. A recent white paper on the Wound Balance concept identifies barriers such as local and systemic factors, misaligned patient goals, and challenges related to dressings.

Introduction: Measuring wound dimensions through traditional methods can be time-consuming and prone to human error. However,  integrating artificial intelligence (AI) into wound care solutions (AI-WCS) has enhanced the assessment process by making it faster and more accurate.

Introduction: Diabetic foot ulcers have a high recurrence rate, with 42% of patients experiencing relapse within two years due to factors such as neuropathy, arteriopathy, and poor offloading and metabolic control.

Introduction: Chronic osteomyelitis, affecting up to 30% of wound cases, is increasing due to diabetes, peripheral vascular disease, and resistant bacteria. It causes significant morbidity, functional impairment, and often recurs after treatment.

Introduction: Over the past decade, wound care has significantly advanced with new materials, technologies, and surgical techniques, though progress has lagged behind fields like surgery and cardiology.

Introduction: Our academic medical center outpatient wound program is led by wound & ostomy certified APRNs with surgeon support as needed, with the clinic staffed by wound & ostomy certified RNs and technicians.

Introduction:  Near infra-red spectroscopy (NIRS) is a non-invasive imaging device that can measure oxygenated and de-oxygenated levels of hemoglobin in the wound and periwound tissues to calculate and create an image of tissue oxygen saturation.

Introduction: Near infra-red spectroscopy (NIRS) has been used to evaluate tissue oxygen saturation and perfusion in a variety of clinical settings including wound care, vascular medicine and surgery.  NIRS has also been used to evaluate the patient’s response to a procedure or therapeutic interv

Introduction: Patients with darker skin tones are at risk for DTPI’s at almost double the rate of patients with lighter skin.1 With racial diversity increasing across the US, and an estimation that darker pigmented nationalities will comprise over half of the population by 2050 2, utilizing skin

Introduction: The Integrated Binder Wrap System (IBWS, patent pending) was developed in a surgical practice based on observed patient needs.  All surgeries require mechanical closure of incisions by means of sutures, staples, glue, etc.  We identified that post-surgical patient manipulation was a

Introduction: Non-healing wounds pose a significant burden on the healthcare system and the patients as they increase the risk of complications, such as infection, amputation, or even death.

Introduction: Chronic wounds, affecting over 6 million Americans, pose significant challenges and an increased risk of amputations 1.

Introduction:

Introduction: Skin grafting is critical for treating severe skin defects and chronic wounds1, particularly those resulting from burns, trauma, and infections.

Introduction: Clinicians often face information overload, making it challenging to keep up with evidence-based practices.1,2 Traditional paper-based pocket guides, which quickly become outdated, have been a common tool for point-of-care decision-making.1 A Portuguese national wound care society*

Introduction: In the setting of a stalled wound despite standard of care, a pinch graft can be performed in the outpatient setting to help promote wound closure.Methods:Partial thickness pinches of skin are taken from a donor site, usually the upper thigh.

Introduction: Osteomyelitis, or infection of the bone, is often seen in association with the diabetic foot ulcer.

Introduction: Chronic venous insufficiency often leads to complications, including venous leg ulcers (VLU). Multispectral near infrared spectroscopy (NIRS) imaging shows promise as an adjunct for assessing microcirculation, providing insights into tissue oxygenation (StO2 ).

Introduction: A novel minimally invasive wound hygiene and debridement technique utilizing Kylon fabric was utilized in the conflict zone setting of the occupied Palestinian Territory of Gaza.

Introduction: Treatment of Pyoderma Gangrenosum is aimed at controlling inflammation, while promoting wound healing and preventing complications.

Introduction:

Introduction: Complex, non healing skin injuries and wounds pose significant physical, emotional and financial challenges for patients, caregivers, clinicians and payers.Methods:83 year old diabetic female (A1C10) with RA on leflutemide presented with bilateral LE ulcerations with exposed bone on

Introduction: Biofilm formation has been reported to cause chronic inflammation and delay healing of wounds, especially chronic and acute dermal wounds. Biofilms formed deep in the wound disrupts healing and is hard to eradicate (1).

Introduction: Recent reports indicate an increase in individuals in the US treated for at least one chronic wound.

Introduction: Diagnostic errors are a common and costly risk for patient harm.1 They occur when a healthcare provider fails to establish an accurate and timely explanation of a patient's health problem and/or communicate this explanation to the patient.2

<p>Introduction: Pain is a very important variable to consider in wound management and wound bed preparation.

Introduction: In the case of cellulitis that is recurrent or recalcitrant despite appropriate antibiotic therapy we propose a surgical technique easily performed as an outpatient.Methods:Elliptical incisions are made through the skin over the area of cellulitis, removing the ellipse.  Using a hem

Introduction: A rare presentation of acute phlegmasia cerulea dolens with pulmonary emboli. Methods: Heparin drip and catheter directed thrombolysis.

Introduction: How not to miss wounds that wound benefit for HBO therapy Methods: Extensive review of all past medical conditions and treat- ments Results: Patient was discovered to have had radiation to an area adja- cent to the non-healing wound Discussion: Everyone needs to be thorough in obta

Introduction: Over the past few years, the opioid crisis has seen a new and dangerous additive in the fentanyl community; the veterinary seda- tive, xylazine, also known as tranq.

Introduction: Skin and soft tissue infections (SSTIs) present signifi- cant challenges in clinical practice, especially due to the growing issue of antibiotic resistance.

Introduction: The purpose of this study was to validate the use of an Indirect Calorimetry (IC) reading to determine a more accurate picture of the caloric need per individual patient with a goal of wound healing.

Introduction: Recurrent acute bacterial skin and skin structure infections (ABSSSI) is diagnosed in 16% to 53% of all ABSSSI cases. Study aim was to describe antibiotic prescription patterns among outpatients diagnosed with ABSSSI who experienced antibiotic failure/intolerance.

Introduction: Venous leg ulcers (VLUs) are traditionally managed with standard of care dressings, compression, and appropriate adjunctive venous interventions for pathologic venous reflux.

Introduction: Epidermolysis bullosa (EB) is a severe genetic disorder affecting epithelial integrity, primarily managed through frequent wound dressing changes. The EASE study demonstrated accelerated wound healing for Oleogel-S10 (birch triterpenes)* in EB (NCT03068780).

Introduction: There is a very scarce literature about the consequences of using multicomponent bandages in a very hot environment. The ma- terials used in these multi-components are theoretically designed to with- stand higher temperatures without losing their compression properties.

Introduction: Tissue perfusion plays a major role in wound healing. Ex- isting techniques fail to provide detailed visualization of perfusion. In this study, we developed a photoacoustic imaging (PAI) system capable of map- ping vascular structures in the foot.

Introduction: The Fitzpatrick Scale, widely used to evaluate skin pigmentation, is a tool developed to assist clinicians in assessing skin in- fection, inflammation and tissue repair.

Introduction: Hard-to-heal wounds pose a significant challenge in healthcare, affecting the quality of life in an estimated 40 million patients worldwide. The management of these wounds places a strain on limited medical resources.

Introduction: Conducting a comprehensive diabetic foot assessment is essential, particularly when it comes to screening for limb perfusion to detect early-stage peripheral artery disease (PAD).

Introduction: Diabetic foot ulcers (DFUs) are a significant and grow- ing public health issue, affecting millions of individuals with diabetes. Chronic DFUs often fail to heal with standard care, leading to prolonged disability, increased healthcare costs, and the risk of amputation.

Introduction: The presence of bacterial colonies that are adherent to the tissue surface are recognized as deterrents to wound healing. The success of surgical reconstruction often relies on the ability to reduce the risk of postoperative infection.

Introduction: Pressure injury with secondary ulceration is a challenge for surgical healing following reconstruction. Previously, we reported the use of placental allografts for incisional management following surgical closure of chronic wounds.

Introduction: Flap mobilization is the mainstay of treatment in pres- sure injury to replace soft tissue loss. Successful outcomes are achieved when there is adequate tissue for transfer.

Introduction: Flap mobilization and closure is the mainstay of treat- ment in soft tissue reconstruction. Successful outcomes are only achieved when there is adequate tissue for transfer.

Introduction: An autologous skin cell suspension(ASCS*) offers a unique alternative to traditional split thickness skin grafting(STSG) by allowing for point-of-care application of an autologous graft in the form of a spray.

Introduction: The increasing prevalence of deep tissue injuries (DTIs) has put a significant strain on healthcare systems, especially in long-term care settings where vulnerable populations are at a higher risk.1 DTIs are different from other pressure injuries (PIs) by developing internal- ly,

Introduction: Diabetic foot ulcers are a severe complication for diabet- ic patients, significantly impacting patient quality of life and healthcare systems efficiency. These ulcers often lead to hospitalization and ampu- tation.

Introduction: This study evaluated intermittent topical oxygen therapy (TWO2) in the treatment of moderately ischemic DFU’s. Methods: Patients included in this study were part of a post hoc analysis of a randomized prospective double-blind study that evaluated TWO2 in treating DFU.

Introduction: Chronic wounds impose high physical, psychosocial burden on patients and costs on healthcare systems.

Introduction: Approaches to preventing sacral pressure injuries in Long-Term Acute Care (LTAC) hospitals may include complementary interventions such as manual rotation, pressure reducing devices, topical agents, and, more recently, dressings.

Introduction: Among patients in Long Term Acute Care (LTAC) hospitals, prevention of sacral pressure injuries requires clinical diligence due to prolonged immobility and higher prevalence of urinary and bowel incontinence.

Introduction: Peripheral Artery Disease (PAD) impairs limb perfusion and compli- cates wound healing, particularly in elderly populations. Early detection of PAD is crucial for guiding therapy and improving outcomes.

Introduction: Diabetic foot ulcer (DFU) are a common complication of diabetes, significantly impacting mobility and quality of life. Assessing walking ability at discharge provides a critical measure for rehabilitation success.

Introduction: Medical adhesive-related skin injuries are defined as to skin damage caused by the use of products containing a medical adhe- sive1. Patients with fragile and/or sensitive skin, may require use of low or non-adherent dressings to help reduce the risk of damage.

Introduction: Chronic wounds present a significant challenge to patient quality of life and to the financial management of healthcare orga- nizations1 .

Introduction: Managing increasingly complex tissue defect wounds op- timally remains challenging. Feasibilities utilizing flaps can be limited, nor are all able to make commitments for them. Failure rates for traditional paradigms can range from 5 – 10%.

Introduction: Wound management is often accompanied by signif- icant pain, which can impede healing and affect patient quality of life. Traditional dressings may address infection but fail to prioritize pain reduction.

Introduction: Caeserean section (CS) rates are growing globally. Cur- rent rates of 21.5% are expected to increase to 28.5% by 2030. The global incidence of surgical site infections (SSI) following a CS is 5.6% with the African region highest with a rate of 11.91%.

Introduction: Diabetic foot ulcers (DFUs) are a frequent and serious complication for patients with diabetes, which significantly impact patient quality of life and pose a substantial burden on healthcare systems.

Introduction: Hospital acquired pressure injuries affect approximately 2.5 million individuals every year , in United States acute care facilities. These wounds represent an enormous burden on global healthcare from both a patient care and a budgetary perspective.

Introduction: Diabetic foot ulcers (DFUs) are a prevalent and serious complication of diabetes, which result in poor patient quality of life and substantial economic burden.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful nodules, abscesses and scarring, primarily affecting apocrine gland-bearing areas.

Introduction: Pyoderma gangrenosum (PG) is a rare, ulcerative neu- trophilic dermatosis that has shown fluctuating incidence over time.

Introduction: Diabetic foot infections (DFIs) are a major cause of diabetes-related hospitalizations and lower limb amputations.

Introduction: Both chronic and acute wounds require suitable manage- ment with an appropriate dressing to ensure the healing process occurs effectively1.

Introduction: Chronic wounds have a significant impact on health- care worldwide.1 Accurate assessment of wound tissue types such as granulation, slough, eschar, and epithelialization is crucial for effective management.2 However, human evaluations can be inconsistent due to knowledge gaps, vi

Introduction: Diabetic ulcers (DUs) are among the most prevalent and challenging chronic wounds, often resulting in prolonged healing times, increased healthcare costs, and reduced patient quality of life.1 Effective management of DUs is critical to prevent complications such as infec- tions a

Introduction: Wounds significantly increase the risk of hospitalization in home health (HH) settings by up to 52%. 1 They also consume a notable portion of HH budgets with the frequent nursing visits for wound assess- ment and care.

Introduction: Wound care management relies on accurate assessment and measurement of wound characteristics, including tissue types such as granulation, slough, eschar, and epithelialization, as well as surface area.

Introduction: Post-thrombotic syndrome (PTS) is one of the most common complications of deep vein thrombosis, affecting up to 50% of patients 1.

Introduction: The Ankle Brachial Index is a widely used diagnos- tic technique for peripheral artery disease. The ABI procedure can be time-consuming, labor intensive, and uncomfortable for patients.

Introduction: Wound images can have errors in color, which may impede diagnosis and distort measurements. 1,2,3 Color errors are caused by technical variability in smartphone camera algorithms and settings, as well as inconsistent photographer technique during image acquisition.

Introduction: The adoption of minimally invasive techniques, such as foam sclerotherapy and radiofrequency ablation (RFA), for treating chronic venous insufficiency has increased significantly over the past decade.¹ While duplex ultrasonography (DUS) remains the gold standard for diagnosing v

Introduction: 5.6 million people are estimated to have diabetes in the UK. 25% of individuals with diabetes go on to develop diabetic foot ulcers (DFUs) in their lifetimes1. DFUs take significant time to heal and often lead to ampu- tations.

Introduction: Hospital-acquired pressure injuries (HAPI) cost in the US exceeds $26.8 billion and affects more than 2.5 people annually.

Introduction: The loss of pedal rays through amputation negatively im- pacts gait, quality of life (QOL), and increases morbidity.

Introduction: Wound care services in home health, hospice, and skilled nursing facilities are crucial to patient recovery. Chronic wounds are challenging due to factors like biofilm, ischemia, and delayed healing, which increase the risk of complications.

Introduction: 47-year-old male presented to the ED, and our service was consulted to see the patient for a diabetic foot infection. He is Diabetic with peripheral neuropathy so he states he never noticed the wound or causing any pain.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the hair follicle with systemic manifestations and a significant impact on quality of life.

Introduction: Diabetic foot infections (DFIs) are a major global health concern due to their potential for serious complications, such as ampu- tation, if not properly managed.

Introduction: Using real-world data (RWD) we conducted a com- parative effectiveness analysis (CEA) of a Dehydrated Amnion Chorion Membrane (dACM)(a) versus a Fetal Bovine Collagen Dressing (FBCD) (b) for the management of diabetic foot ulcers (DFUs).

Introduction: Diabetes mellitus is the most rapidly growing cause of the global disease burden. DFUs are a manifestation of diabetes associ- ated with difficult/delayed wound healing and a five-year mortality rate of 13-42%.

Introduction: Pulsed electromagnetic field (PEMF) therapy has proven to be effective in acute tissue healing and pain reduction. It encourages the growth, maintenance and healing of living cells, soothes muscle pain and stiffness, and improves tissue oxygenation and blood circulation.

Introduction: Chronic hard-to-heal wounds, such as diabetic foot ulcers (DFUs), venous leg ulcers (VLUs), and pressure ulcers, pose significant safety risks, burdens on patients, and challenges to health- care systems worldwide.

Introduction: Approximately 8,000,000 people experience low levels of health literacy in the US.

Introduction: Lymphedema of limbs is an accumulation of tissue fluid in the tissue space due to lymphatic vessel damage or insufficiency.

Introduction: Lipedema of the lower limb is a pathological accumu- lation of adipose tissue. Depending on the type of lipedema, the adipose tissue accumulates in different parts of the lower body but never in the foot.

Introduction: Lymphedema of the lower limb is an accumulation of tissue fluid in tissue space due to lymphatic damage or insufficiency. However, depending on etiology and advancement, the sites of fluid accu- mulation and tissue secondary changes are different.

Introduction: The presence of high bioburden levels and pH levels in wounds has been proven to delay wound healing and significantly affect wound healing rates. The use of the Detec pH device allows monitoring of wound pH changes without contact with the wound.

Introduction: 58-year-old male admitted with Fournier’s Gangrene with new onset of diabetes mellitus and severe sepsis. Emergent surgical debridement resulted in a large wound to the peri-rectal, perineum and groin region. Hartmann’s procedure was completed to protect wound.

Introduction: Lymphangioma Circumscriptum (LC) is a rare, benign condition characterized by fluid-filled blisters or wart-like growths, commonly found on the abdomen, axillae, or mouth.

Introduction: Body-contouring procedures following weight loss are prone to complications including delayed wound healing, secondary wound dehiscence, postoperative hematoma, or seroma.

Introduction: Tissue necrosis and infection stall wound healing and can lead to other complications, including disseminated infection and ampu- tation.1 For wound care patients at risk of lower limb amputation, rapid conversion from infected nonhealing wounds to healing wounds is essen- tial in

Introduction: Chronic wounds that do not respond to the standard wound treatment therapies impact a patient’s economic well-being and general quality of life and require clinicians to incorporate innovative and effective wound care strategies.

Introduction: Tunneling and undermining continue to complicate podiatric wound management. Cellular, acellular, and matrix-based prod- ucts (CAMPs) are often utilized as a part of standard of care to achieve wound closure in complex podiatric wounds.

Introduction: The prevalence of diabetes mellitus in Indonesia ranks as the fifth highest in the world (IDF 2021). Diabetic foot (DF) is one of the most common and serious chronic complications of diabetes.

Introduction: Diabetic foot ulcers (DFUs) are a very common side effect of diabetes and are considered as chronic wounds that impact healthcare systems and patient quality of life. Even more problematic are patients with significant co-morbidities and a history of complica- tions.

Introduction: In the hospice setting, wound care is heavily focused on symptom management. This case series describes trialing a novel silicone foam dressing* on multiple patients receiving hospice services.

Introduction: Second-degree burns often result in significant tissue damage, necessitating advanced therapeutic approaches to accelerate healing and reduce complications.

Introduction: The Achilles tendon region is noted to be a historically complex area to heal wounds due to its known poor vascular supply. Multiple different theories have been proposed of the exact angiosome supply to this region, most famously by Taylor and Attinger.

Introduction: Deep pressure ulcers (PU) secondary to spinal cord injury are among the most challenging conditions in public health, both to treat and to prevent. Approximately 1–3 million people in the United States (US) develop pressure ulcers each year.

Introduction: Autologous growth factors, particularly platelet-rich plasma (PRP), have drawn attention for their vital role in chronic wound healing, promoting tissue formation and epithelialization. PRP, which contains a concentrated form of growth factors, can accelerate healing.

Introduction: Radiation dermatitis is one of the most common side effects of radiotherapy treatment for cancer, affecting over 90% of patients receiving it.

Introduction: Pyoderma Gangrenosum (PG) is a rare neutrophilic dermatosis causing rapidly progressive ulcers. It is often associated with systemic conditions like inflammatory bowel disease (IBD), rheumatoid arthritis (RA), and hematologic malignancies.

Introduction: Wagner grade 2 to 4 diabetic foot ulcers (DFUs) present substantial challenges in limb salvage.

Introduction: Chronic dermatological diseases, including Hidradenitis Suppurativa (HS), Pyoderma Gangrenosum (PG), and Venous Ulcers (VU), significantly affect health-related quality of life (HRQoL). These conditions impose physical, psychological, and social burdens that vary in severity.

Introduction: Adhesion formation between repaired tendons and surrounding tissues is one of the main complications after tendon repair resulting in poor clinical outcome.

Introduction: Full-thickness skin burn wounds may be challenging to treat, even more so on animals. This is true not only for their unique skin flora but also due to their particular and more unpredictable behavior.

Introduction: Despite repeated excisional debridements and aggressive wound care burn wounds, traumatic injuries, surgical wounds from ab- dominal catastrophes and necrotizing soft tissue infections (NSTI) may remain heavily colonized.

Introduction: Non-healing wounds can represent a significant clinical challenge. Autografting with freshly harvested minced full-thickness skin grafts can enhance healing but can also present technical challenges.

Introduction: Dog bite wounds, particularly those involving the hands, present complex challenges due to the risk of infection, involvement of deep structures, and the need for precise wound management to preserve functionality.

Introduction: Diabetes has become a very prevalent disease in the United States. Up to 39% of diabetic patients will develop a diabetic foot ulcer (DFU), with about 1.6 million DFUs treated each year.

Introduction: Symmetric peripheral gangrene (SPG) is characterized by peripheral ischemic lesions without significant vascular occlusion. SPG mortality rates range from 40% to 90%.

Introduction: Atherosclerosis affecting the lower extremities frequently results in rest pain, non-healing ulcers and extensive soft tissue loss. Peripheral arterial disease affects 8-10 million people in the USA (3).

Introduction: Management of deep, tunneling, undermining and pressure wounds can be challenging. Cellular, acellular, and synthetic matrices that come in powdered, morcellated, or flowable forms can be useful for filling deep wound spaces and reducing wound volumes to promote closure.

Introduction: Effective wound care requires balancing infection man- agement with patient comfort. Polyhexamethylene biguanide (PHMB) dressings have emerged as a solution for reducing microbial load while minimizing pain, particularly during dressing changes.

Introduction: With an underreported prevalence of 2.5 million in the United States, pressure ulcers are associated with pain, infection, and high mortality rates1.

Introduction: Empyema usually develops after pneumonia and contig- uous spread from skin and soft tissue infection is very uncommon.

Introduction: Osteomyelitis of the calcaneus is a leading cause of below-knee amputations and requires urgent attention and intervention. A new product is making significant strides in transforming the treatment of osteomyelitis infections.

Introduction: Infection and chronic inflammation are critical factors that obstruct wound healing. These factors slow healing progress and increase the risk of infection in the wound bed. This underscores the urgency for new dressings.

Introduction: Amputation, regardless of the type, leads to long-term complications. When we change the structure of the foot, we create new pressure points that increase the risk of developing new ulcers.

Introduction: Pilonidal sinus disease (PSD) is an inflammatory condi- tion affecting hair follicles beneath the skin of the sacro-coccygeal region. PSD is acquired through local trauma and hair penetration, inducing a foreign body reaction.

Introduction: Among wood workers using powered cutting equip- ment, hand injuries and distal fingertip amputations are common. In fact, woodworking equipment produces approximately 720,000 injuries per year with up to 60.5% of injuries occurred to amateur woodworkers.

Introduction: An 85-year-old male patient with a past medical history of chronic venous insufficiency (CVI), hyperlipidemia, GERD, hyperten- sion, and former tobacco use presented with a non-healing left lower extremity wound.

Introduction: It is estimated that 18.6 million people worldwide and 1.6 million in the US are affected by diabetic foot ulcers annually [1]. Synthetic materials such as bioactive glass are becoming commercially relevant as the next generation of skin substitutes.

Introduction: Vaporous Hyperoxia Therapy (VHT) represents a prom- ising approach for the management of chronic wounds, particularly in cases such as diabetic foot ulcers, pressure ulcers, and venous insufficien- cy ulcers.

Introduction: Wound dehiscence can become a serious postoperative complication commonly associated with pain, infection, and delayed healing. These wounds can have complex features such as tunneling and draining, often requiring advanced wound care therapies.

Introduction: Heart Failure is defined as a syndrome caused by an anomaly in the structure and/or function of the heart, with the greatest impact on global public health, and one of the main causes of morbidity and mortality throughout the world.

Introduction: A 44-year-old woman with a colostomy for metastatic rectal cancer developed an ulcer under her pouch system. A large inci- sional hernia was present on her midline as well as a parastomal hernia.

Introduction: Up to 3/1000 people are estimated to have leg ulcers with prevalence increasing to 20/1000 for people >80 years old. 1 These lower extremity wounds are often chronic, highly exudative, and associ- ated with venous insufficiency.

Introduction: Negative pressure wound therapy (NPWT) is widely utilized in wound management.1-3 However, challenges exist with its use such as maintaining a seal in difficult anatomical locations, controlling exudate, periwound skin management, and pain upon dressing removal.

Introduction: Pressure injuries account for 2.5 million hospitaliza- tions in the United States, making it the third most costly disease, with more than 60,000 deaths resulting from disease complications.

Introduction: Clinical Problem: Wound healing has been shown to be impeded by the presence of bacterial biofilms which exist in most chronic wounds. It is not surprising that biofilm disruption is the focus of wound management and essential to the healing process.

Introduction: Diabetic Foot Ulcers (DFUs) and Venous Leg Ul- cers (VLUs) represent significant healthcare challenges in the United States, exacerbated by demographic shifts such as an aging population and increasing rates of chronic diseases like diabetes and obesity.

Introduction: According to the America Society of Plastic Surgeons (ASPS), society members performed almost 162,000 abdominoplasty procedures in 2022.

Introduction: Hidradenitis suppurativa (HS) is a chronic and debili- tating inflammatory skin condition necessitating a multidisciplinary ap- proach, including medical management, surgical intervention, and wound care.

Introduction: Flame burn victims are forced to live a life of long-lasting morbidity. Delayed wound healing affect patients not only physically, but mentally. Various treatments are used to treat chronic wounds but the best treatment is still debatable.

Introduction: The average length of a song is approximately three to four minutes.

Introduction: Nitric oxide (NO) plays a critical role in the regulation of various wound healing processes, including perfusion, inflammatory response, cell proliferation, collagen formation, antimicrobial action, angiogenesis, wound contraction, and epithelialization.1-3 For patients with ch

Introduction: Hernia repair remains one of the most common surgical procedures in the United States, with over 700,000 cases annually utilizing mesh.

Introduction: Chronic wounds, particularly in patients with diabetic ulcers, represent a significant healthcare challenge due to underlying metabolic dysfunctions such as insulin resistance and glucose toxicity.

Introduction: Moisture-associated skin damage, MASD, is a very common issue in healthcare settings, especially for people at risk of im- mobility or incontinence.

Introduction: Wound healing is a complex physiological process that involves a series of coordinated events. Oxygen and insulin play critical roles in this pro- cess, influencing various cellular and molecular mechanisms facilitating tissue repair.

Introduction: Chronic, non-healing wounds pose significant challenges in clinical practice, placing substantial burdens on patients, caregivers, healthcare providers, and payers.¹,² A multimodal therapeutic strategy, enhanced by advanced monitoring technologies, is critical for achiev- ing opt

Introduction: Traditional negative pressure wound therapy (NPWT) has been utilized for both wound bed preparation and as a bolster over grafts.

Introduction: The problem that was addressed by our wound clinic was that we had hard to heal chronic wounds that had been present often times for greater than 6 months in patients with diabetes.

Introduction: Vaporous Hyperoxia Therapy (VHT)* combines hydra- tion with concentrated oxygen to enhance wound healing. Methods: To evaluate VHT’s efficacy in resolving chronic wounds in a high-risk diabetic patient through two distinct wound cases treated in 2019 and 2024.

Introduction: Peripheral vascular disease (PVD) is a global issue affecting roughly 200 million people. This disease comes secondary to atherosclerosis of vessels and can lead to complications such as lower extremity ulceration and amputation [1].

Introduction: Post surgical wounds with the complication of dehis- cence present a challenge in compromised patients. When traditional incision re-closure is not an option, secondary intent closure is the goal.

Introduction: Desloughing of wounds is a critical first step to healing and considered a low-risk form of debridement. Slough is the yellowish/whitish, gelatinous/stringy material that covers wound surfaces and impairs healing by creating a bacterial burden.

Introduction: Chronic wounds represent a significant challenge in clinical practice, particularly when traditional therapies fail to induce healing1.

Introduction: Treatment guidelines for unstageable heel pressure recommend leaving eschars intact and taking a conservative approach due to a poor prognosis for healing.

Introduction: Approximately 67% of patients with diabetes melli- tus have deep venous incompetence lower legs.

Introduction: 60% of diabetic foot ulcers (DFUs) were reported to have infection and the treatment strategies with infected DFUs are mostly surgery and antibiotics with standard moisturizing dressing and literature has reported the incidence of wound closure at only 27.5% in 6 months and 44.5

Introduction: Chronic wounds are a significant healthcare problem in the United States. Their costs exceed 25 billion dollars in the United States.

Introduction: Major limb amputation is a life-altering procedure affecting approximately 2 million Americans, a number projected to double by 2050.

Introduction: Acute radiation dermatitis (ARD) is a common adverse effect of radiotherapy, particularly in cases where the skin is included in the target volume, such as head and neck cancer or breast cancer.

Introduction: The purpose of this case study is to demonstrate the efficacy of combining adipose injectable filler, dermal matrix, and porcine urinary bladder matrix in the management of a complex achilles wound.

Introduction: Healing chronic wounds is particularly challenging when an exposed structure such as bone or tendon is present due to poor vascu- larization surrounding these structures.

Introduction: Chronic venous disease (CVD) affects an estimated 2.5–6 million individuals in the United States, with about 20% developing lipodermatosclerosis (LDS).

Introduction: The reconstructive ladder serves as a stepwise approach in determining an appropriate path to reconstruction and wound closure. The addition of skin substitutes has provided a plethora of advanced tissue grafts to support the goals of reconstruction.

Introduction: Open tibial fractures can lead to amputation, which affects patients physiologically and psychologically1 and increases the one-year mortality rate by 47.9%.2 Ovine forestomach matrix (OFM) has been utilized for limb salvage and reconstruction.

Introduction: Lower extremity wounds present a complex challenge, often with several etiologies collaboratively delaying wound healing. Inflammatory symptoms of venous or lymphedema ulcers are commonly mistaken for infection, further delaying wound improvement.

Introduction: Trans metatarsal amputation (TMA) is commonly performed to address complications of diabetic foot ulcers, including in- fection and ischemia.

Introduction: Great toe amputation is frequently performed to address infected foot ulcers. Due to underlying comorbidities and condition of the distal foot, healing can be compromised, even after removal of non- viable tissue.

Introduction: Hidradenitis Suppurativa (HS) is a chronic, painful, and debilitating condition that severely impacts patients’ quality of life.

Introduction: The presence of slough and biofilm in a wound are barriers in the wound healing cascade preventing movement out the in- flammatory phase into the proliferative phase and onto healing.

Introduction: CVD affects approximately 25% of the U.S. population, often progressing from leg heaviness and itching to edema, dermatitis, and ulceration. Early recognition and treatment can prevent disease progression.

Introduction: We present a case of a 56-year-old diabetic male with an 18 month old non-healing ulcer of the left lower leg that was initially misdiagnosed and worsened despite antibiotics, debridement, and stan- dard wound care.

Introduction: Introduction: This study evaluates MPM Medical wound care products’ clinical efficacy, patient comfort, and clinician usability during a 15-day medical mission in Tonga. The mission targeted chronic ulcers, trauma wounds, and abscesses in a resource-limited environment.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammato- ry skin disorder which affects the folliculopilosebacous unit.

Introduction: Trauma to the extremities represents one of the most common injury forms leading to large, full thickness soft tissue loss. Achieving closure after extensive debridement of necrotic tissue can be challenging, especially in patients with multiple co-morbidities.

Introduction: Lower extremity wounds often pose unique treatment challenges to both clinicians and patients. Because of such challenges, it is often necessary to utilize a combination of different techniques, modalities, and products to successfully treat lower extremity wounds.

Introduction: Air-dried human amniotic membrane (dHAM) is a ster- ile placental allograft derived from amniotic membrane tissue developed for wound healing.

Introduction: Air-dried human amniotic membrane (dHAM) is a sterile placental allograft derived from amniotic membrane tissue devel- oped for wound healing applications.

Introduction: Fish skin graft (FSG) is a xenograft derived from Atlantic cod that augments wound healing1. This case evaluates FSG* in a patient with nonhealing traumatic ulcers with cellulitis on the left lower leg which had not responded to conservative wound care.

Introduction: Tardive dyskinesia (TD) is a movement disorder characterized by involuntary movements developing from dopamine receptor-blocking agents, with long term use of first-generation anti- psychotics associated with higher risk1.

Introduction: Desiccated human amniotic membrane (DHAM) is a chorion-free allograft derived from amniotic membrane tissue.

Introduction: Advanced wound care technologies offer valuable in- sights into healing processes. This study explores the use of tissue oxygen saturation (StO2) and temperature analytics in clinical decision-making for complex wounds.

Introduction: Chronic and complex wounds present significant challenges due to the presence of debris and biofilm, which hinder the healing process. Effective wound bed preparation is essential, as inade- quate cleansing and debridement can delay healing and elevate the risk of infection.

Introduction: Wound cleansing, performed at every wound care appointment, is necessary to put stalled wounds back onto a healing trajectory and to prevent infection and its complications.

Introduction: Keloid scars result from excessive collagen produc- tion and fibroblast proliferation following dermal injury or inflamma- tion, commonly affecting African Americans.

Introduction: Prevalence estimates for total diabetes were 10.3% in 2001–2004 and 13.2% in 2017–2020 (1). Diabetic foot ulcer is a major complication of diabetes. Every year in the United States, there are 150,000 amputations (2), with a majority of people with diabetes.

Introduction: The National Diabetes Statistics in 2021 estimated that 38.4 million people had diabetes. The change in foot morphology affects the plantar pressure at the metatarsal heads, causing a callus that can be- come an ulcer.

Introduction: Degloving injuries of the lower extremity refers to deep, penetrating injuries that extend into underlying structures such as mus- cle, tendon, ligament, bone, and neurovascular tissue structures.

Introduction: Hidradenitis Suppurativa (HS) is a chronic, multifactorial inflammatory skin condition characterized by tissue destruction, painful lesions and frequent recurrences.

Introduction: Healing chronic diabetic foot ulcers (DFU) can be incredibly challenging, especially those with exposed structures such as bone, tendon, or ligaments or deep into the hypodermis.

Introduction: 45-year-old female presented to the wound care clinic with an atypical wound to the left medial lower extremity. The patient reported trauma at the etiology resulting in a small black bump that gradually worsened.

Introduction: Surgical site infection (SSI) is an adverse clinical outcome that significantly drives morbidity resulting in important human and economic burden.

Introduction: Purpose: to highlight the importance of evaluating for arterial insufficiency at bedside in a young female patient with history of smoking and diabetes mellitus.

Introduction: Complex soft tissue defects (CSTDs) represent a sig- nificant challenge in wound management due to substantial tissue loss, infection, poor vascularization, or anatomically difficult locations where primary closure, including skin grafts or flap coverage, is not feasible in a sin

Introduction: Traditional wound care techniques, although widely utilized, present specific limitations that can impact clinical outcomes.

Introduction: Plantar ulcers, common in diabetic neuropathic indi- viduals with fat pad atrophy, account for nearly half of all foot ulcers and are a leading cause of limb amputations, with rates exceeding 80%.

Introduction: Chronic wounds, which affect millions globally, substan- tially reduce the patients’ quality of life and place significant burdens on healthcare systems.

Introduction: Squamous Cell Carcinoma (SCC) is the second most common type of skin cancer1. It presents as a superficial, non-healing chronic rash or an invasive red papule, nodule, or plaque.

Introduction: Wounds with exposed structures are challenging due to slow healing and high rates of infection and complications.

Introduction: Venous Leg Ulcers (VLUs) are challenging wounds associated with healthcare costs estimated at >$32 billion annually1, given the delayed healing and high recurrence rates, with only 60% closing by 12 weeks and 75% reappearing within 3 weeks2.

Introduction: Lower limb venous ulcerations in patients with multiple comorbidities present a multifactorial clinical challenge, often unfortu- nately progressing to amputation.

Introduction: Reliable methods of assessing flap viability beyond visual inspection would conserve tissue flaps and improve outcomes. Near-in- frared spectroscopy is a non-invasive, non-contact way of assessing oxygenation and perfusion status of superficial tissue.

Introduction: This case study describes the successful closure of a stage 3 pressure injury to the right below-the-knee amputation secondary to prosthesis rubbing using a novel silicone foam dressing.* The patient had previously trialed eight topical treatments in combination with week- ly sha

Introduction: Infection is one of the leading causes of delayed healing in chronic wounds. If left undiagnosed, wounds can remain stagnant for weeks, months, and even years.

Introduction: Patients with diabetes are at an increased risk of amputation, especially if they have previously undergone amputation or ablative surgery on the ipsilateral foot.