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Atypical Wounds Topic Center

Case Series
Unusual Clinical Presentations of Cutaneous Squamous Cell Involving Distal Extremities in Four Patients: The Importance of Tissue Sampling
05/03/2023
Carolyn Ziemer; Jayson Miedema; Scott Jaros; Paul Googe
The authors present four cases in which wounds originally thought to be nonhealing ulcers or cellulitis were revealed to be cancerous upon tissue sampling.
The authors present four cases in which wounds originally thought to be nonhealing ulcers or cellulitis were revealed to be cancerous upon tissue sampling.
The authors present four cases...
05/03/2023
Wounds
Unusual Wounds
The Novel Use of Cryopreserved Human Allograft in Extensive Hurley Stage III Hidradenitis Suppurativa
04/10/2023
David Matera; Lisa Jacob
The authors detail a case in which cryopreserved human allograft was successfully used as a bridge to skin grafting in a 37-year-old male with Hurley stage III hidradenitis suppurativa.
The authors detail a case in which cryopreserved human allograft was successfully used as a bridge to skin grafting in a 37-year-old male with Hurley stage III hidradenitis suppurativa.
The authors detail a case in...
04/10/2023
Wounds
Case Report
Pancreatic Panniculitis Secondary to Pancreatic Cyst With Lower Extremity Wounds as a Primary Presenting Feature: A Case Report and Literature Review
04/05/2023
Richard Simman, MD, FACS, FACCWS; Assava-Aree Chompunut; Lauren Fang; Samar Ayoub
The authors detail the cases of a 68-year-old male with pancreatic panniculitis characterized by erythematous wounds of the lower extremities and histology that included "ghost cells."
The authors detail the cases of a 68-year-old male with pancreatic panniculitis characterized by erythematous wounds of the lower extremities and histology that included "ghost cells."
The authors detail the cases of...
04/05/2023
Wounds
Case Report
Calciphylaxis and Skin Ulcers: A Diagnostic and Therapeutic Challenge
03/14/2023
Emanuela Francisco; Carlos Casimiro; Aline A. Gomes; Raquel Barros Pereira
In this case report, a 55-year-old White male was admitted with chronic necrotic ulcers on the right leg and an irregular violaceous plaque on the left leg under an initial suspicion of necrotizing fasciitis; following a diagnosis of...
In this case report, a 55-year-old White male was admitted with chronic necrotic ulcers on the right leg and an irregular violaceous plaque on the left leg under an initial suspicion of necrotizing fasciitis; following a diagnosis of...
In this case report, a...
03/14/2023
Wounds
Case Report
Platelet-rich Plasma Injection for Enterocutaneous Fistula: A Case Report
12/28/2022
Limin Bai; Gang Xu; Haijun Lin
A 52-year-old male patient diagnosed with an enterocutaneous fistula was treated with one application of platelet-rich plasma and saw fistula closure within 2 weeks.
A 52-year-old male patient diagnosed with an enterocutaneous fistula was treated with one application of platelet-rich plasma and saw fistula closure within 2 weeks.
A 52-year-old male patient...
12/28/2022
Wounds
Preview Image
Videos
Performing a Wound Biopsy to Diagnose Atypical Wounds
10/28/2022
Windy E. Cole, DPM, CWSP, FACCWS
In this video, Dr. Windy E. Cole reports the results of a case series in which 3 patients who presented with rare diseases—atypical wounds—were diagnosed via biopsy results. Data were presented at the 2022 SAWC Fall.
In this video, Dr. Windy E. Cole reports the results of a case series in which 3 patients who presented with rare diseases—atypical wounds—were diagnosed via biopsy results. Data were presented at the 2022 SAWC Fall.
In this video, Dr. Windy E. Cole...
10/28/2022
Wounds
Review
Atypical Ulcers: A Stepwise Approach for Clinicians
09/22/2022
Igor A. Altman; Maria M. Tsoukas; Melissa A. Nickles, BA; William J. Ennis; Nadera Sweiss
The authors share a stepwise approach for identifying, diagnosing, and treating atypical ulcers in this review.
The authors share a stepwise approach for identifying, diagnosing, and treating atypical ulcers in this review.
The authors share a stepwise...
09/22/2022
Wounds
Review
Understanding the Zebras of Wound Care: An Overview of Atypical Wounds
05/03/2022
Elizabeth A. Ansert, MA, DPM, MBA; Weldon Murry; Donald Cohen, DPM; Anthony Tickner, DPM, FRCPS, FACCWS, FAPWH, FAPWCA; Samuel Gorelik, DPM
This review provides a general overview of various atypical wound etiologies, clinical presentations and appearance, and current treatment protocols.
This review provides a general overview of various atypical wound etiologies, clinical presentations and appearance, and current treatment protocols.
This review provides a general...
05/03/2022
Wounds
Case Report
Atypical Ulcer Arising on Stasis Dermatitis: Achromic Melanoma
03/03/2022
Valentina Dini; Angelo D'Erme; Giulia Davini; Marco Romanelli; Barbara Loggini; Agata Janowska; Cristian Fidanzi; Giovanni Bagnoni
The authors report a very rare case of malignant melanoma in a 70-year-old female with stasis dermatitis.
The authors report a very rare case of malignant melanoma in a 70-year-old female with stasis dermatitis.
The authors report a very rare...
03/03/2022
Wounds

From the Publications

Case Series
Unusual Clinical Presentations of Cutaneous Squamous Cell Involving Distal Extremities in Four Patients: The Importance of Tissue Sampling
05/03/2023
Carolyn Ziemer; Jayson Miedema; Scott Jaros; Paul Googe
The authors present four cases in which wounds originally thought to be nonhealing ulcers or cellulitis were revealed to be cancerous upon tissue sampling.
The authors present four cases in which wounds originally thought to be nonhealing ulcers or cellulitis were revealed to be cancerous upon tissue sampling.
The authors present four cases...
05/03/2023
Wounds
Case Report
Pancreatic Panniculitis Secondary to Pancreatic Cyst With Lower Extremity Wounds as a Primary Presenting Feature: A Case Report and Literature Review
04/05/2023
Richard Simman, MD, FACS, FACCWS; Assava-Aree Chompunut; Lauren Fang; Samar Ayoub
The authors detail the cases of a 68-year-old male with pancreatic panniculitis characterized by erythematous wounds of the lower extremities and histology that included "ghost cells."
The authors detail the cases of a 68-year-old male with pancreatic panniculitis characterized by erythematous wounds of the lower extremities and histology that included "ghost cells."
The authors detail the cases of...
04/05/2023
Wounds
Case Report
Calciphylaxis and Skin Ulcers: A Diagnostic and Therapeutic Challenge
03/14/2023
Emanuela Francisco; Carlos Casimiro; Aline A. Gomes; Raquel Barros Pereira
In this case report, a 55-year-old White male was admitted with chronic necrotic ulcers on the right leg and an irregular violaceous plaque on the left leg under an initial suspicion of necrotizing fasciitis; following a diagnosis of...
In this case report, a 55-year-old White male was admitted with chronic necrotic ulcers on the right leg and an irregular violaceous plaque on the left leg under an initial suspicion of necrotizing fasciitis; following a diagnosis of...
In this case report, a...
03/14/2023
Wounds
Case Report
Platelet-rich Plasma Injection for Enterocutaneous Fistula: A Case Report
12/28/2022
Limin Bai; Gang Xu; Haijun Lin
A 52-year-old male patient diagnosed with an enterocutaneous fistula was treated with one application of platelet-rich plasma and saw fistula closure within 2 weeks.
A 52-year-old male patient diagnosed with an enterocutaneous fistula was treated with one application of platelet-rich plasma and saw fistula closure within 2 weeks.
A 52-year-old male patient...
12/28/2022
Wounds
Review
Atypical Ulcers: A Stepwise Approach for Clinicians
09/22/2022
Igor A. Altman; Maria M. Tsoukas; Melissa A. Nickles, BA; William J. Ennis; Nadera Sweiss
The authors share a stepwise approach for identifying, diagnosing, and treating atypical ulcers in this review.
The authors share a stepwise approach for identifying, diagnosing, and treating atypical ulcers in this review.
The authors share a stepwise...
09/22/2022
Wounds
Review
Understanding the Zebras of Wound Care: An Overview of Atypical Wounds
05/03/2022
Elizabeth A. Ansert, MA, DPM, MBA; Weldon Murry; Donald Cohen, DPM; Anthony Tickner, DPM, FRCPS, FACCWS, FAPWH, FAPWCA; Samuel Gorelik, DPM
This review provides a general overview of various atypical wound etiologies, clinical presentations and appearance, and current treatment protocols.
This review provides a general overview of various atypical wound etiologies, clinical presentations and appearance, and current treatment protocols.
This review provides a general...
05/03/2022
Wounds
Case Report
Atypical Ulcer Arising on Stasis Dermatitis: Achromic Melanoma
03/03/2022
Valentina Dini; Angelo D'Erme; Giulia Davini; Marco Romanelli; Barbara Loggini; Agata Janowska; Cristian Fidanzi; Giovanni Bagnoni
The authors report a very rare case of malignant melanoma in a 70-year-old female with stasis dermatitis.
The authors report a very rare case of malignant melanoma in a 70-year-old female with stasis dermatitis.
The authors report a very rare...
03/03/2022
Wounds
Case Series
Use of Synthetic Electrospun Fiber Matrix in the Sealing of Tunneling, Undermining, and Cavity Wounds
04/08/2026
Thea Price, MD; Katie Meador, NP
In a retrospective series, synthetic electrospun fiber matrix promoted healing of complex tunneling and undermining wounds, helping avoid flap reconstruction or amputation in high-risk patients.
In a retrospective series, synthetic electrospun fiber matrix promoted healing of complex tunneling and undermining wounds, helping avoid flap reconstruction or amputation in high-risk patients.
In a retrospective series,...
04/08/2026
Wounds
Case Series
Rethinking Compression: Expanding Decongestive Therapy With Innovative Garment Solutions
03/27/2026
Suzie Ehmann, PT, DPT, PhD Candidate, CWS, CWLT, CLT-LANA
This case series shows that a dual-layer compression system can effectively reduce limb volume, support wound healing, and improve patient independence in complex lymphedema.
This case series shows that a dual-layer compression system can effectively reduce limb volume, support wound healing, and improve patient independence in complex lymphedema.
This case series shows that a...
03/27/2026
Wounds
Literature Review
Application of Nanofiber Wound Dressings in Diabetic Wound Healing: A Review and Economic Considerations
03/18/2026
Gemma Toogood, BS; Harrison Smith, BS ; Meghan Underwood, BS; Robin Evans, MD; Junwang Xu, PhD
Electrospun nanofiber dressings enhance diabetic wound healing via targeted therapeutic delivery, promoting angiogenesis and inflammation control.
Electrospun nanofiber dressings enhance diabetic wound healing via targeted therapeutic delivery, promoting angiogenesis and inflammation control.
Electrospun nanofiber dressings...
03/18/2026
Wounds
Original Research
The Effect of Negative Pressure Wound Therapy on Abdominal Deep Incisional Surgical Site Infections in High-Risk Patients
03/12/2026
03/12/2026
Wounds
Case Series
Successful Application of Bilayer Living Skin Substitute in the Treatment of Pyoderma Gangrenosum: A Case Series
03/10/2026
Eight refractory pyoderma gangrenosum cases healed with immunosuppression, selective debridement, and bilayer skin substitute, supporting surgery under controlled inflammation.
Eight refractory pyoderma gangrenosum cases healed with immunosuppression, selective debridement, and bilayer skin substitute, supporting surgery under controlled inflammation.
Eight refractory pyoderma...
03/10/2026
Wounds
Original Research
Preserving Limbs and Lives: The Role of Cellular, Acellular, and Matrix-like Products in Diabetic Foot Ulcer Care
02/26/2026
Abigail Royfman, BS; Sarah Lux, BA; Kennedy Couch, BS; Molynna Nguyen, BS; Mandy Wong, BS; Emily Gong, BS; Richard Simman, MD
CAMPs may reduce long-term lower-limb amputation risk and improve amputation-free survival in diabetic foot ulcer care.
CAMPs may reduce long-term lower-limb amputation risk and improve amputation-free survival in diabetic foot ulcer care.
CAMPs may reduce long-term...
02/26/2026
Wounds
Case Report
Hydrosurgical Debridement System Combined With Negative Pressure Wound Therapy for the Treatment of Large Chronic Wounds Caused by Polyacrylamide Hydrogel Injection for Breast Augmentation
02/24/2026
Hydrosurgical debridement combined with negative pressure therapy effectively treated extensive chronic wounds from polyacrylamide hydrogel breast injections, resulting in successful healing without recurrence at 12–18 months.
Hydrosurgical debridement combined with negative pressure therapy effectively treated extensive chronic wounds from polyacrylamide hydrogel breast injections, resulting in successful healing without recurrence at 12–18 months.
Hydrosurgical debridement...
02/24/2026
Wounds
Case Report
Treatment of Refractory Leg Ulcer in a Patient With Lupus Undergoing Combination Therapies
02/11/2026
Chi Young Bang, MD, PhD; Seung Ho Lee, MD; Kun Yong Sung, PhD, MD
Systemic lupus erythematosus may present with refractory leg ulcers unresponsive to immunosuppression, prompting consideration of multimodal anticoagulation and advanced wound therapies.
Systemic lupus erythematosus may present with refractory leg ulcers unresponsive to immunosuppression, prompting consideration of multimodal anticoagulation and advanced wound therapies.
Systemic lupus erythematosus may...
02/11/2026
Wounds
Case Report
Negative Pressure Wound Therapy-Assisted Granulation and Grafting Over Exposed Achilles Tendon in an Immunocompromised Burn Patient
02/06/2026
Mohamad Kharashgah, MBBS; Qusai Swedan, MD; Saleh Abualhaj, MD
This case report explores management considerations for full-thickness burns with exposed Achilles tendon in an immunocompromised patient.
This case report explores management considerations for full-thickness burns with exposed Achilles tendon in an immunocompromised patient.
This case report explores...
02/06/2026
Wounds
Case Report
Plantar-to-Plantar Punch Skin Grafts for a Wound Caused by Crush Injury
01/28/2026
Francisco Javier Ramírez-Fernández, MD; Isidro Velázquez-Jacobo, MD; Adriana Lozano-Platonoff, MD; Monica Navarrete-Martínez, MD; José Contreras-Ruiz, MD
This case report discusses region-specific reconstruction of complex foot trauma using plantar-to-plantar punch grafting to provide durable, glabrous coverage.
This case report discusses region-specific reconstruction of complex foot trauma using plantar-to-plantar punch grafting to provide durable, glabrous coverage.
This case report discusses...
01/28/2026
Wounds

Multimedia

Preview Image
Videos
Performing a Wound Biopsy to Diagnose Atypical Wounds
10/28/2022
Windy E. Cole, DPM, CWSP, FACCWS
In this video, Dr. Windy E. Cole reports the results of a case series in which 3 patients who presented with rare diseases—atypical wounds—were diagnosed via biopsy results. Data were presented at the 2022 SAWC Fall.
In this video, Dr. Windy E. Cole reports the results of a case series in which 3 patients who presented with rare diseases—atypical wounds—were diagnosed via biopsy results. Data were presented at the 2022 SAWC Fall.
In this video, Dr. Windy E. Cole...
10/28/2022
Wounds
Analysis
Notes on Financial and Legal Implications of Measurement Inconsistencies and CTPs
03/26/2026
Scott Nelson
This speaker discusses the audit implications of inaccuracies in wound care documentation, highlighting the importance of maintaining documentation integrity at practices of any size.
This speaker discusses the audit implications of inaccuracies in wound care documentation, highlighting the importance of maintaining documentation integrity at practices of any size.
This speaker discusses the audit...
03/26/2026
Wounds
Analysis
What Are the Risks of Measurement Inaccuracy With CTPs?
03/23/2026
Scott Nelson
This author emphasizes that inconsistencies in measurement of wounds for CTPs can lead to red flags for auditors, as erratic size changes or consistent overestimations may suggest improper billing practices.
This author emphasizes that inconsistencies in measurement of wounds for CTPs can lead to red flags for auditors, as erratic size changes or consistent overestimations may suggest improper billing practices.
This author emphasizes that...
03/23/2026
Wounds
Analysis
Measurement Accuracy and CTPs: Viewpoints on Driving Outcomes
03/19/2026
Scott Nelson
In the first of three videos, this speaker focuses on the critical role of measurement accuracy in wound care, emphasizing its impact on medical necessity and reimbursement processes.
In the first of three videos, this speaker focuses on the critical role of measurement accuracy in wound care, emphasizing its impact on medical necessity and reimbursement processes.
In the first of three videos,...
03/19/2026
Wounds
Analysis
Implementation of Three Unexpected CTP 2026 Medicare Payment Changes: Part 3
03/17/2026
Now that Medicare is no longer paying for CTP wastage, Kathleen D. Schaum discusses how to adjust your processes to accommodate that change.
Now that Medicare is no longer paying for CTP wastage, Kathleen D. Schaum discusses how to adjust your processes to accommodate that change.
Now that Medicare is no longer...
03/17/2026
Wounds
Analysis
Implementation of Three Unexpected CTP 2026 Medicare Payment Changes: Part 2
03/13/2026
Kathleen D. Schaum, MS
In the second part of this video series, Kathleen Schaum explores exceptions to the Medicare CTP payment of $127.14 per square centimeter.
In the second part of this video series, Kathleen Schaum explores exceptions to the Medicare CTP payment of $127.14 per square centimeter.
In the second part of this video...
03/13/2026
Wounds
Analysis
Implementation of Three Unexpected CTP 2026 Medicare Payment Changes: Part 1
03/11/2026
Kathleen D. Schaum, MS
In part 1 of a video series, Kathleen D. Schaum breaks down how to implement using the same allowable payment rate for all brands of CTP sheets.
In part 1 of a video series, Kathleen D. Schaum breaks down how to implement using the same allowable payment rate for all brands of CTP sheets.
In part 1 of a video series,...
03/11/2026
Wounds
Viewpoints
CTPs at a Turning Point: Regulation, Innovation, and Market Pressures Ahead
03/03/2026
David Alper, DPM
In this interview, the speaker outlines concerns about regulatory overcorrection, escalating product costs, and the growing influence of vendor-driven revenue messaging in physician offices.
In this interview, the speaker outlines concerns about regulatory overcorrection, escalating product costs, and the growing influence of vendor-driven revenue messaging in physician offices.
In this interview, the speaker...
03/03/2026
Wounds
Viewpoints
CTPs at a Crossroads: Navigating Regulation, Access, and Limb Preservation
02/24/2026
David Alper, DPM
As multi-billion dollar spending on CTPs draws heightened regulatory scrutiny, policymakers are stepping in—fast and forcefully. But as new rules roll out, many clinicians worry that cost containment efforts could unintentionally undermine...
As multi-billion dollar spending on CTPs draws heightened regulatory scrutiny, policymakers are stepping in—fast and forcefully. But as new rules roll out, many clinicians worry that cost containment efforts could unintentionally undermine...
As multi-billion dollar spending...
02/24/2026
Wounds
Viewpoints
Right Patient, Right Product, Right Time: A Smarter Approach to CTP Use
02/16/2026
Frank Aviles, Jr., PT, CWS, FACCWS, CLT-LANA, ALM, AWCC
Advanced wound imaging technologies—including near-infrared spectroscopy, thermography, and fluorescence imaging—are transforming how clinicians select and time cellular tissue product (CTP) applications.
Advanced wound imaging technologies—including near-infrared spectroscopy, thermography, and fluorescence imaging—are transforming how clinicians select and time cellular tissue product (CTP) applications.
Advanced wound imaging...
02/16/2026
Wounds
Viewpoints
CTP Regulatory Shifts: What’s Next and a Practical Reality Check
02/10/2026
Jim McDannald, DPM
In this part of a recent interview with Jim McDannald, DPM, of Podiatry Growth, he shares how he sees practices adapting in light of regulatory changes, and what he predicts for those that do not find a way to do so.
In this part of a recent interview with Jim McDannald, DPM, of Podiatry Growth, he shares how he sees practices adapting in light of regulatory changes, and what he predicts for those that do not find a way to do so.
In this part of a recent...
02/10/2026
Wounds

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