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Poll: Treating Acute Severe Ulcerative Colitis

Rebecca Mashaw
12/17/2024

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FDA Approval
FDA Approves Ustekinumab for Pediatric Ulcerative Colitis
09/01/2026
Rebecca Mashaw
Ustekinumab was approved for Crohn's disease in pediatric patients age 2 and older in April 2026.
Ustekinumab was approved for Crohn's disease in pediatric patients age 2 and older in April 2026.
Ustekinumab was approved for...
09/01/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Dana Lukin, MD, on Ulcerative Proctitis
07/07/2026
Raymond Cross, MD; Dana Lukin, MD
Drs Raymond Cross and Dana Lukin review isolated ulcerative proctitis, including risk factors, diagnosis, mimics, and cancer surveillance.
Drs Raymond Cross and Dana Lukin review isolated ulcerative proctitis, including risk factors, diagnosis, mimics, and cancer surveillance.
Drs Raymond Cross and Dana Lukin...
07/07/2026
Advances in Inflammatory Bowel Disease Network
Maria Abreu
Research Insights
Maria Abreu, MD, on the DUET-UC Trial of Combination Therapy
05/19/2026
Maria Abreu, MD
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a...
05/19/2026
Advances in Inflammatory Bowel Disease Network
Research Review
Mirikizumab Shows Progressive Histologic Improvement in Ulcerative Colitis, With Strong Rectal Response
05/06/2026
Jessica Garlewicz
The study uniquely focused on patients with baseline bowel urgency, integrating symptom burden with objective mucosal healing endpoints.
The study uniquely focused on patients with baseline bowel urgency, integrating symptom burden with objective mucosal healing endpoints.
The study uniquely focused on...
05/06/2026
Advances in Inflammatory Bowel Disease Network

Latest News

Research Highlights
Combined Ultrasound and Calprotectin at 3 Months Predict Postoperative Recurrence in Crohn’s Disease
05/07/2026
Jessica Garlewicz
High specificity and positive predictive value suggest that patients meeting both thresholds are at high risk for early recurrence and may need closer monitoring.
High specificity and positive predictive value suggest that patients meeting both thresholds are at high risk for early recurrence and may need closer monitoring.
High specificity and positive...
05/07/2026
Advances in Inflammatory Bowel Disease Network
News
Oral Icotrokinra Demonstrates Efficacy in Ulcerative Colitis Regardless of Prior Advanced Therapy Exposure
05/05/2026
Jessica Garlewicz
While response rates were generally higher in patients without prior advanced therapy failure, meaningful improvements were still seen in those with treatment-resistant disease.
While response rates were generally higher in patients without prior advanced therapy failure, meaningful improvements were still seen in those with treatment-resistant disease.
While response rates were...
05/05/2026
Advances in Inflammatory Bowel Disease Network
Research Review
Early “Top-Down” Therapy Reduces Long-Term Complications in Crohn’s Disease
05/05/2026
Jessica Garlewicz
Disease progression and hospitalizations were more common in the step-up group, with higher rates of stricturing and penetrating complications.
Disease progression and hospitalizations were more common in the step-up group, with higher rates of stricturing and penetrating complications.
Disease progression and...
05/05/2026
Advances in Inflammatory Bowel Disease Network
Research Review
Upper GI Crohn’s Disease Remains Underrecognized, Lacks Standardized Guidance
04/02/2026
Jessica Garlewicz
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of...
04/02/2026
Advances in Inflammatory Bowel Disease Network
Research Summary
Advanced Therapy May Reduce Antibiotic Dependence in Chronic Pouchitis After IPAA
03/18/2026
Jessica Garlewicz
These findings support considering immune-mediated therapy in selected patients although more research is needed to identify the patients likely to benefit most from advanced therapy.
These findings support considering immune-mediated therapy in selected patients although more research is needed to identify the patients likely to benefit most from advanced therapy.
These findings support...
03/18/2026
Advances in Inflammatory Bowel Disease Network
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
News
Medicare Will Cover GLP-1s for Obesity Under Deal with Pharma
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
FDA Approves Updated Indication for Upadacitinib in IBD
10/14/2025
Rebecca Mashaw
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for...
10/14/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Concomitant Medications Do Not Alter Efficacy of Advanced Therapies in Ulcerative Colitis, Study Finds
09/18/2025
Jessica Garlewicz
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that...
09/18/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Persistent Prothrombotic State Observed in Patients With ASUC
09/04/2025
Rebecca Mashaw
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with...
09/04/2025
Advances in Inflammatory Bowel Disease Network

Latest Podcasts

IBD Drive time logo
Expert Insights
IBD Drive Time: Rebecca Brown, MD, on Controversies in IBD Surgery
09/15/2026
Raymond Cross, MD; Rebecca Brown, MD
Host Raymond Cross, MD, and colorectal surgeon Rebecca Brown, MD, discuss surgical therapies for Crohn's disease and ulcerative colitis, including controversies about the best approaches.
Host Raymond Cross, MD, and colorectal surgeon Rebecca Brown, MD, discuss surgical therapies for Crohn's disease and ulcerative colitis, including controversies about the best approaches.
Host Raymond Cross, MD, and...
09/15/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Gursimran Kocchar, MD, on Medical and Endoscopic Management of Strictures in Crohn's Disease
08/28/2026
Raymond Cross, MD; Gursimran S. Kochhar
Host Raymond Cross, MD, brings in Dr Gursiman Kocchar to share his expertise in the management of strictures in Crohn's disease, from medical therapies to endoscopic procedures to surgery.
Host Raymond Cross, MD, brings in Dr Gursiman Kocchar to share his expertise in the management of strictures in Crohn's disease, from medical therapies to endoscopic procedures to surgery.
Host Raymond Cross, MD, brings...
08/28/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
Marla Dubinsky, MD, on Lifelong Reproductive Care for Women With IBD
08/05/2026
Raymond Cross, MD; Marla C. Dubinsky, MD
Dr Marla Dubinsky joins host Raymond Cross, MD, for a discussion about how inflammatory bowel disease affects women's reproductive health beyond childbearing, from choosing contraception and using hormonal replacement therapy in perimenopause.
Dr Marla Dubinsky joins host Raymond Cross, MD, for a discussion about how inflammatory bowel disease affects women's reproductive health beyond childbearing, from choosing contraception and using hormonal replacement therapy in perimenopause.
Dr Marla Dubinsky joins host...
08/05/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Dana Lukin, MD, on Ulcerative Proctitis
07/07/2026
Raymond Cross, MD; Dana Lukin, MD
Drs Raymond Cross and Dana Lukin review isolated ulcerative proctitis, including risk factors, diagnosis, mimics, and cancer surveillance.
Drs Raymond Cross and Dana Lukin review isolated ulcerative proctitis, including risk factors, diagnosis, mimics, and cancer surveillance.
Drs Raymond Cross and Dana Lukin...
07/07/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Jennifer Seminerio, MD, on Advanced Combination Therapy
06/12/2026
Raymond Cross, MD; Jennifer Seminerio, MD
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss...
06/12/2026
Advances in Inflammatory Bowel Disease Network
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Expert Insights
IBD Drive Time: Jordan Axelrad, MD, on Communicating Risks to Patients With IBD
05/22/2026
Raymond Cross, MD; Jordan Axelrad, MD
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan...
05/22/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Colleen Kelly, MD, on Obesity and IBD
04/20/2026
Raymond Cross, MD; Colleen Kelly, MD
Host Raymond Cross, MD, calls on Dr Colleen Kelly to discuss the increasing prevalence of obesity among patients with IBD, how obesity can complicate Crohn's disease and ulcerative colitis, and the role of GLP-1 RAs and bariatric surgery in...
Host Raymond Cross, MD, calls on Dr Colleen Kelly to discuss the increasing prevalence of obesity among patients with IBD, how obesity can complicate Crohn's disease and ulcerative colitis, and the role of GLP-1 RAs and bariatric surgery in...
Host Raymond Cross, MD, calls on...
04/20/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Jared Magee, MD, on Men's Health in IBD
04/07/2026
Raymond Cross, MD; Jared Magee, MD
Drs Raymond Cross and Jared Magee discuss some of the special concerns that affect men with inflammatory bowel disease, from cardiac concerns to sexual dysfunction and assessing for anal cancer.
Drs Raymond Cross and Jared Magee discuss some of the special concerns that affect men with inflammatory bowel disease, from cardiac concerns to sexual dysfunction and assessing for anal cancer.
Drs Raymond Cross and Jared...
04/07/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: The Best of ECCO 2026
03/25/2026
Raymond Cross, MD; Sara Horst, MD; Jordan Axelrad, MD
Host Raymond Cross, MD, is joined by Drs Sara Horst and Jordan Axelrad to review the findings of their picks for the best presentations from the European Crohn's and Colitis Organization meeting held earlier this year.
Host Raymond Cross, MD, is joined by Drs Sara Horst and Jordan Axelrad to review the findings of their picks for the best presentations from the European Crohn's and Colitis Organization meeting held earlier this year.
Host Raymond Cross, MD, is...
03/25/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
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IBD Drive Time: Shirley Cohen-Mekelburg, MD on Self-Care for IBD Patients
03/17/2026
Shirley Cohen-Mekelburg; Raymond Cross, MD
Host Raymond Cross, MD, calls on Dr Shirley Mekelburg-Cohen to discuss the importance of self-care among patients with IBD, what self-care consists of, and how to help patients learn to partner with their clinicians in controlling their...
Host Raymond Cross, MD, calls on Dr Shirley Mekelburg-Cohen to discuss the importance of self-care among patients with IBD, what self-care consists of, and how to help patients learn to partner with their clinicians in controlling their...
Host Raymond Cross, MD, calls on...
03/17/2026
Advances in Inflammatory Bowel Disease Network

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