Poster
176
(#176) From Evidence to Intervention: A Scoping Review of Treatments for Inhalant and Volatile Substance Misuse
Psych Congress 2025
Abstract: Inhalant and volatile substance misuse present significant challenges to society, yet the treatment options have largely been overlooked. Currently, there are no FDA-approved pharmacotherapies for inhalant use disorders. Additionally, there are limited nonpharmacological studies focused on the treatment and management of the disorders. These limitations have made it difficult to establish a standardized approach when treating the disorder and have limited the treatment options available to individuals facing the addiction.
This scoping review examines the proposed treatment options for inhalant and volatile substance misuse. It categorizes the proposed treatments and specifically outlines their effectiveness and limiting factors. The review utilized multiple databases such as PubMed, ScienceDirect, and PsycINFO to explore various case reports, public health reports, clinical trials, and community-based programs. There was a focus on studies and reports that specifically explored the pharmacological, psychosocial, supportive, and holistic approaches in treating and managing the disorder.
The treatment of inhalant and volatile substance misuse has been approached through various mechanisms. Multiple studies and reports involving the supportive, holistic, pharmacological, and psychosocial approaches have successfully demonstrated varying levels of success when managing inhalant and volatile substance misuse. Yet, no FDA-approved pharmacological treatment or standardized approaches have been developed for managing the disorder. The literature review found that many of the approaches have only demonstrated efficacy on smaller scales and were limited by a culturally specific context. Therefore, further research employing large-scale and multifaceted methodologies is necessary to establish the efficacy and replicability of these interventions.
Short Description: This scoping review examines treatment approaches for inhalant and volatile substance misuse, a neglected addiction with no FDA-approved therapies. It evaluates supportive, pharmacological, holistic, and psychosocial interventions, highlighting successes and limitations. Findings show promise in culturally tailored and multifaceted programs, but most evidence comes from small-scale studies, underscoring the urgent need for large-scale, standardized, and replicable treatment research.
Name of Sponsoring Organization(s): N/A
This scoping review examines the proposed treatment options for inhalant and volatile substance misuse. It categorizes the proposed treatments and specifically outlines their effectiveness and limiting factors. The review utilized multiple databases such as PubMed, ScienceDirect, and PsycINFO to explore various case reports, public health reports, clinical trials, and community-based programs. There was a focus on studies and reports that specifically explored the pharmacological, psychosocial, supportive, and holistic approaches in treating and managing the disorder.
The treatment of inhalant and volatile substance misuse has been approached through various mechanisms. Multiple studies and reports involving the supportive, holistic, pharmacological, and psychosocial approaches have successfully demonstrated varying levels of success when managing inhalant and volatile substance misuse. Yet, no FDA-approved pharmacological treatment or standardized approaches have been developed for managing the disorder. The literature review found that many of the approaches have only demonstrated efficacy on smaller scales and were limited by a culturally specific context. Therefore, further research employing large-scale and multifaceted methodologies is necessary to establish the efficacy and replicability of these interventions.
Short Description: This scoping review examines treatment approaches for inhalant and volatile substance misuse, a neglected addiction with no FDA-approved therapies. It evaluates supportive, pharmacological, holistic, and psychosocial interventions, highlighting successes and limitations. Findings show promise in culturally tailored and multifaceted programs, but most evidence comes from small-scale studies, underscoring the urgent need for large-scale, standardized, and replicable treatment research.
Name of Sponsoring Organization(s): N/A


