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Depression Topic Center

woman experiencing depression
News
12/01/2025
Maria Mantas
A systematic review and meta-analysis of 7 clinical trials and 4 published protocol papers found that nitrous oxide (N2O) may offer rapid-acting benefit for the treatment of depression.
A systematic review and meta-analysis of 7 clinical trials and 4 published protocol papers found that nitrous oxide (N2O) may offer rapid-acting benefit for the treatment of depression.
A systematic review and...
12/01/2025
Psych Congress Network
Pop quiz written on a blackboard with white chalk
Quiz
11/19/2025
Brionna Mendoza
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
11/19/2025
Psych Congress Network
open and spilled bottle of pills
News
11/03/2025
Maria Mantas
According to a recent systematic review and meta-analysis, the physiological effects of antidepressants vary greatly, particularly for cardiometabolic parameters.
According to a recent systematic review and meta-analysis, the physiological effects of antidepressants vary greatly, particularly for cardiometabolic parameters.
According to a recent systematic...
11/03/2025
Psych Congress Network
brain
News
10/03/2025
Maria Mantas
Personalized high-definition transcranial direct current stimulation (HD-tDCS) induced a significantly greater improvement in mood in patients with depression compared to those who underwent sham treatment.
Personalized high-definition transcranial direct current stimulation (HD-tDCS) induced a significantly greater improvement in mood in patients with depression compared to those who underwent sham treatment.
Personalized high-definition...
10/03/2025
Psych Congress Network
child embraces mother
News
09/02/2025
Maria Mantas
Child depression at ages 10 and 11 years during the COVID-19 pandemic was significantly associated with later maternal depression, according to longitudinal study results.
Child depression at ages 10 and 11 years during the COVID-19 pandemic was significantly associated with later maternal depression, according to longitudinal study results.
Child depression at ages 10 and...
09/02/2025
Psych Congress Network
sticky note that reads "take the quiz"
Quiz
07/31/2025
Maria Mantas
Do you remember what the medication's guideline suggests?
Do you remember what the medication's guideline suggests?
Do you remember what the...
07/31/2025
Psych Congress Network
pencil erasers that spell out the word "quiz"
Quiz
07/14/2025
Maria Mantas
Do you remember the clinical guideline recommendations?
Do you remember the clinical guideline recommendations?
Do you remember the clinical...
07/14/2025
Psych Congress Network
brain scan
News
07/14/2025
Maria Mantas
Regional homogeneity (ReHo)–magnetic resonance imaging (MRI) cortical deficit patterns may serve as a sensitive functional biomarker for major depressive disorder (MDD), according to a recent case-control study.
Regional homogeneity (ReHo)–magnetic resonance imaging (MRI) cortical deficit patterns may serve as a sensitive functional biomarker for major depressive disorder (MDD), according to a recent case-control study.
Regional homogeneity...
07/14/2025
Psych Congress Network
a woman with depression
News
07/08/2025
Maria Mantas
Initial data from the core stage of a phase 2b clinical trial showed that an intranasal formulation of mebufotenin benzoate, BPL-003, significantly reduced depressive symptoms in patients with treatment-resistant depression (TRD).
Initial data from the core stage of a phase 2b clinical trial showed that an intranasal formulation of mebufotenin benzoate, BPL-003, significantly reduced depressive symptoms in patients with treatment-resistant depression (TRD).
Initial data from the core stage...
07/08/2025
Psych Congress Network
depressed woman
News
06/27/2025
Maria Mantas
Transcranial electrical stimulation (tES) was well-tolerated and associated with positive outcomes among depressive patients with and without comorbidities, according to a recent review and meta-analysis.
Transcranial electrical stimulation (tES) was well-tolerated and associated with positive outcomes among depressive patients with and without comorbidities, according to a recent review and meta-analysis.
Transcranial electrical...
06/27/2025
Psych Congress Network
older man comforted by younger man
News
06/06/2025
Maria Mantas
Depression in mid and late-life is linked to an increased risk of dementia, according to new research published in eClinicalMedicine. 
Depression in mid and late-life is linked to an increased risk of dementia, according to new research published in eClinicalMedicine. 
Depression in mid and late-life...
06/06/2025
Psych Congress Network

News

open and spilled bottle of pills
News
11/03/2025
Maria Mantas
According to a recent systematic review and meta-analysis, the physiological effects of antidepressants vary greatly, particularly for cardiometabolic parameters.
According to a recent systematic review and meta-analysis, the physiological effects of antidepressants vary greatly, particularly for cardiometabolic parameters.
According to a recent systematic...
11/03/2025
Psych Congress Network
brain
News
10/03/2025
Maria Mantas
Personalized high-definition transcranial direct current stimulation (HD-tDCS) induced a significantly greater improvement in mood in patients with depression compared to those who underwent sham treatment.
Personalized high-definition transcranial direct current stimulation (HD-tDCS) induced a significantly greater improvement in mood in patients with depression compared to those who underwent sham treatment.
Personalized high-definition...
10/03/2025
Psych Congress Network
child embraces mother
News
09/02/2025
Maria Mantas
Child depression at ages 10 and 11 years during the COVID-19 pandemic was significantly associated with later maternal depression, according to longitudinal study results.
Child depression at ages 10 and 11 years during the COVID-19 pandemic was significantly associated with later maternal depression, according to longitudinal study results.
Child depression at ages 10 and...
09/02/2025
Psych Congress Network
brain scan
News
07/14/2025
Maria Mantas
Regional homogeneity (ReHo)–magnetic resonance imaging (MRI) cortical deficit patterns may serve as a sensitive functional biomarker for major depressive disorder (MDD), according to a recent case-control study.
Regional homogeneity (ReHo)–magnetic resonance imaging (MRI) cortical deficit patterns may serve as a sensitive functional biomarker for major depressive disorder (MDD), according to a recent case-control study.
Regional homogeneity...
07/14/2025
Psych Congress Network
a woman with depression
News
07/08/2025
Maria Mantas
Initial data from the core stage of a phase 2b clinical trial showed that an intranasal formulation of mebufotenin benzoate, BPL-003, significantly reduced depressive symptoms in patients with treatment-resistant depression (TRD).
Initial data from the core stage of a phase 2b clinical trial showed that an intranasal formulation of mebufotenin benzoate, BPL-003, significantly reduced depressive symptoms in patients with treatment-resistant depression (TRD).
Initial data from the core stage...
07/08/2025
Psych Congress Network
depressed woman
News
06/27/2025
Maria Mantas
Transcranial electrical stimulation (tES) was well-tolerated and associated with positive outcomes among depressive patients with and without comorbidities, according to a recent review and meta-analysis.
Transcranial electrical stimulation (tES) was well-tolerated and associated with positive outcomes among depressive patients with and without comorbidities, according to a recent review and meta-analysis.
Transcranial electrical...
06/27/2025
Psych Congress Network
older man comforted by younger man
News
06/06/2025
Maria Mantas
Depression in mid and late-life is linked to an increased risk of dementia, according to new research published in eClinicalMedicine. 
Depression in mid and late-life is linked to an increased risk of dementia, according to new research published in eClinicalMedicine. 
Depression in mid and late-life...
06/06/2025
Psych Congress Network
person holding brain scans
News
04/29/2025
Maria Mantas
Neuroimaging and clinical features models predicting response to antidepressant treatment in adults with MDD showed significant generalizability to other randomized clinical trials (RCTs) in a recent study.
Neuroimaging and clinical features models predicting response to antidepressant treatment in adults with MDD showed significant generalizability to other randomized clinical trials (RCTs) in a recent study.
Neuroimaging and clinical...
04/29/2025
Psych Congress Network
Hormonal Contraceptive Pills
News
04/09/2025
Jolynn Tumolo
The initiation of hormonal contraception post partum was associated with an immediate increase in depression risk in first-time mothers in Denmark, according to a study published in JAMA Network Open.
The initiation of hormonal contraception post partum was associated with an immediate increase in depression risk in first-time mothers in Denmark, according to a study published in JAMA Network Open.
The initiation of hormonal...
04/09/2025
Psych Congress Network
depressed woman
News
04/04/2025
Maria Mantas
Adhering to specific dietary patterns, including the Mediterranean diet, may reduce symptoms of depression, according to a recent literature review published in The Australian and New Zealand Journal of Psychiatry.
Adhering to specific dietary patterns, including the Mediterranean diet, may reduce symptoms of depression, according to a recent literature review published in The Australian and New Zealand Journal of Psychiatry.
Adhering to specific dietary...
04/04/2025
Psych Congress Network
illustration of a brain
News
01/12/2026
Maria Mantas
Processing speed remains one of the most severely impaired cognitive domains in people with schizophrenia, according to a large systematic review and meta-analysis published in JAMA Psychiatry.
Processing speed remains one of the most severely impaired cognitive domains in people with schizophrenia, according to a large systematic review and meta-analysis published in JAMA Psychiatry.
Processing speed remains one of...
01/12/2026
Psych Congress Network
woman on a hill
News
01/09/2026
Maria Mantas
A new multi-site study suggests that while delay discounting is elevated in patients with remitted MDD, it neither changes after antidepressant medication discontinuation nor predicts subsequent depressive relapse.
A new multi-site study suggests that while delay discounting is elevated in patients with remitted MDD, it neither changes after antidepressant medication discontinuation nor predicts subsequent depressive relapse.
A new multi-site study suggests...
01/09/2026
Psych Congress Network
An illustration of a brain
News
01/06/2026
Sarah Fleming
In a study published in Schizophrenia Research, investigators examined whether disease duration or antipsychotic exposure explains increases in brain age among patients with schizophrenia using MRI-based machine-learning models.
In a study published in Schizophrenia Research, investigators examined whether disease duration or antipsychotic exposure explains increases in brain age among patients with schizophrenia using MRI-based machine-learning models.
In a study published in...
01/06/2026
Psych Congress Network
Two pill bottles tipped over with pills on a table
News
01/06/2026
Sarah Fleming
New research published in BMJ Mental Health leveraged national United Kingdom (UK) health registry data to investigate whether selective serotonin reuptake inhibitor (SSRI) treatment in adolescents with unipolar depression influences later...
New research published in BMJ Mental Health leveraged national United Kingdom (UK) health registry data to investigate whether selective serotonin reuptake inhibitor (SSRI) treatment in adolescents with unipolar depression influences later...
New research published in BMJ...
01/06/2026
Psych Congress Network
artificial intelligence
News
01/05/2026
Maria Mantas
A large UK study reports that an artificial intelligence (AI)–enabled clinical prediction model may accurately identify individuals at risk of developing psychotic disorders or bipolar disorders.
A large UK study reports that an artificial intelligence (AI)–enabled clinical prediction model may accurately identify individuals at risk of developing psychotic disorders or bipolar disorders.
A large UK study reports that an...
01/05/2026
Psych Congress Network
a group of clinicians
News
01/02/2026
Maria Mantas
A collaborative care model tailored for low-resource primary care settings did not improve outcomes beyond enhanced usual care for adults with OUD and co-occurring depression and/or PTSD.
A collaborative care model tailored for low-resource primary care settings did not improve outcomes beyond enhanced usual care for adults with OUD and co-occurring depression and/or PTSD.
A collaborative care model...
01/02/2026
Psych Congress Network
A woman with insomnia lying in bed trying to sleep
News
01/02/2026
Sarah Fleming
A narrative review in PLOS Mental Health synthesizes evidence on the bidirectional relationship between sleep and psychiatric disorders and highlights shared neurobiological mechanisms that span major depression, bipolar disorder (BD),...
A narrative review in PLOS Mental Health synthesizes evidence on the bidirectional relationship between sleep and psychiatric disorders and highlights shared neurobiological mechanisms that span major depression, bipolar disorder (BD),...
A narrative review in PLOS...
01/02/2026
Psych Congress Network
A person's hands typing on a smartphone
News
12/29/2025
Sarah Fleming
A smartphone-delivered digital cognitive behavioral therapy (DCBT) program significantly improved symptoms of generalized anxiety disorder (GAD) in adults, according to a randomized clinical trial published in JAMA Network Open.
A smartphone-delivered digital cognitive behavioral therapy (DCBT) program significantly improved symptoms of generalized anxiety disorder (GAD) in adults, according to a randomized clinical trial published in JAMA Network Open.
A smartphone-delivered digital...
12/29/2025
Psych Congress Network
brain illustration
News
12/18/2025
Maria Mantas
An analysis from the multicenter PRONIA consortium reports that integrated peripheral inflammatory markers and whole-brain gray matter volumes can distinguish early-stage depression from psychosis.
An analysis from the multicenter PRONIA consortium reports that integrated peripheral inflammatory markers and whole-brain gray matter volumes can distinguish early-stage depression from psychosis.
An analysis from the multicenter...
12/18/2025
Psych Congress Network
FDA approval stamp
News
12/16/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the first at-home transcranial direct current stimulation (tDCS) device for the treatment of moderate to severe major depressive disorder (MDD).
The US Food and Drug Administration (FDA) has approved the first at-home transcranial direct current stimulation (tDCS) device for the treatment of moderate to severe major depressive disorder (MDD).
The US Food and Drug...
12/16/2025
Psych Congress Network

Quizzes

Pop quiz written on a blackboard with white chalk
Quiz
11/19/2025
Brionna Mendoza
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
11/19/2025
Psych Congress Network
sticky note that reads "take the quiz"
Quiz
07/31/2025
Maria Mantas
Do you remember what the medication's guideline suggests?
Do you remember what the medication's guideline suggests?
Do you remember what the...
07/31/2025
Psych Congress Network
pencil erasers that spell out the word "quiz"
Quiz
07/14/2025
Maria Mantas
Do you remember the clinical guideline recommendations?
Do you remember the clinical guideline recommendations?
Do you remember the clinical...
07/14/2025
Psych Congress Network
sticky note that reads "take the quiz"
Quiz
05/23/2025
Maria Mantas
Do you remember the details of this study?
Do you remember the details of this study?
Do you remember the details of...
05/23/2025
Psych Congress Network
Pop quiz written on a blackboard with white chalk
Quiz
12/23/2024
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
12/23/2024
Psych Congress Network
Are men or women more affected by depressive episodes?
Quiz
12/17/2024
Pop quiz!
Pop quiz!
Pop quiz!
12/17/2024
Psych Congress Network
Pop quiz written on a blackboard with white chalk
Quiz
03/04/2024
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge...
03/04/2024
Psych Congress Network
Three illustrated faces, one sad, one neutral, one happy.
Quiz
01/08/2024
Test your psychiatry knowledge with this quiz!
Test your psychiatry knowledge with this quiz!
Test your psychiatry knowledge...
01/08/2024
Psych Congress Network
Pop quiz written on a blackboard with white chalk
Quiz
11/20/2023
Can you ace this psychiatry quiz?
Can you ace this psychiatry quiz?
Can you ace this psychiatry quiz?
11/20/2023
Psych Congress Network
Pencils spell out quiz.
Quiz
09/25/2023
Test your psychiatry knowledge with this quick quiz!
Test your psychiatry knowledge with this quick quiz!
Test your psychiatry knowledge...
09/25/2023
Psych Congress Network
illustration of a laptop screen displaying a test
Quiz
12/22/2025
Maria Mantas
Do you remember the findings from this systematic review?
Do you remember the findings from this systematic review?
Do you remember the findings...
12/22/2025
Psych Congress Network
Joseph Goldberg, MD
Quiz
12/03/2025
Joseph F. Goldberg, MD
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
12/03/2025
Psych Congress Network
Pop quiz written on a blackboard with white chalk
Quiz
11/19/2025
Brionna Mendoza
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
11/19/2025
Psych Congress Network
quiz
Quiz
11/10/2025
Maria Mantas
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
11/10/2025
Psych Congress Network
a teenager's hand putting a bag of white pills into another teenager's hand.
Quiz
10/23/2025
Curb misuse before it starts—test your diversion-prevention game in 3 quick questions.
Curb misuse before it starts—test your diversion-prevention game in 3 quick questions.
Curb misuse before it...
10/23/2025
Psych Congress Network
Edward Kaftarian, MD
Quiz
10/09/2025
Edward Kaftarian, MD
Do you remember Dr Kaftarian's recommended strategies for building patient rapport via telehealth?
Do you remember Dr Kaftarian's recommended strategies for building patient rapport via telehealth?
Do you remember Dr Kaftarian's...
10/09/2025
Psych Congress Network
A woman sleeping peacefully
Quiz
10/09/2025
Sleep and ADHD intersect—see if your management playbook is up to date in 3 quick questions.
Sleep and ADHD intersect—see if your management playbook is up to date in 3 quick questions.
Sleep and ADHD intersect—see if...
10/09/2025
Psych Congress Network
Blocks that spell ADHD with pills and a stethoscope
Quiz
10/08/2025
Rethink ADHD beyond stimulants—test your non-stimulant savvy with 3 quick questions.
Rethink ADHD beyond stimulants—test your non-stimulant savvy with 3 quick questions.
Rethink ADHD beyond...
10/08/2025
Psych Congress Network
A boy sleeping peacefully.
Quiz
09/29/2025
How well do you know the evidence on ADHD and sleep? Take this quick quiz to find out.
How well do you know the evidence on ADHD and sleep? Take this quick quiz to find out.
How well do you know the...
09/29/2025
Psych Congress Network
a cloud with three z's
Quiz
09/19/2025
Can you optimize ADHD control and protect sleep? Take this quick quiz on viloxazine ER’s role in patients with nighttime challenges.
Can you optimize ADHD control and protect sleep? Take this quick quiz on viloxazine ER’s role in patients with nighttime challenges.
Can you optimize ADHD control...
09/19/2025
Psych Congress Network

Psych Congress Posters

Up to 50% of adults with schizophrenia switch antipsychotic medication within 2 years of treatment initiation. We conducted a real-world analysis of strategies used by healthcare provider...
10/17/2025
This real-world claims analysis compared combined olanzapine/samidorphan (OLZ/SAM) versus olanzapine in patients with bipolar I disorder. OLZ/SAM was associated with significantly better ...
10/17/2025
Short description: Prior pharmacokinetic studies of X/T in healthy volunteers showed dosing with food reduced trospium bioavailability, potentially impacting tolerability. This open-label...
10/17/2025
TV-44749 is a once-monthly subcutaneous long-acting injectable olanzapine, designed to provide sustained efficacy without the risk of post-injection delirium/sedation syndrome (PDSS). Her...
10/17/2025
CRESCENDO was a survey of the patient experience in adults with narcolepsy type 1. This subgroup analysis examined residual symptoms among respondents who reported satisfaction with curre...
10/17/2025
Jazz DUET (NCT05875974) was a patient-centric, prospective, single-arm, open-label study evaluating effectiveness of low-sodium oxybate (LXB) in IH or narcolepsy. In participants with IH,...
10/17/2025
Severe hypothyroidism can present with predominant psychiatric and cognitive symptoms, making diagnosis challenging when classic somatic signs are absent. This poster explores the neurops...
10/17/2025
A 65-year-old male veteran with no prior psychiatric history and a past medical history of seizure disorder developed severe, treatment-resistant depression after witnessing his mother’s ...
10/17/2025
This project explores the integration of mindfulness meditation with esketamine in the treatment of major depressive disorder. Conducted as a quasi-experimental pilot, the study involved ...
10/17/2025
Cognitive processing therapy (CPT) can be effective in treating posttraumatic stress disorder (PTSD). Stellate ganglion block (SGB), which is an anesthetic injection that helps “reset” sy...
10/17/2025