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a woman holds a baby on her lap
Research Summary
Digital Intervention Reduces Perinatal Anxiety During Pregnancy and Postpartum
11/05/2026
Maria Mantas
A self-led digital intervention targeting repetitive negative thinking significantly reduced anxiety during pregnancy and after childbirth, according to recent findings.
A self-led digital intervention targeting repetitive negative thinking significantly reduced anxiety during pregnancy and after childbirth, according to recent findings.
A self-led digital intervention...
11/05/2026
Psych Congress Network
intranasal spray bottles
Research Summary
Mebufotenin Shows Rapid Antidepressant Effects in Phase 2b Trial
11/02/2026
Brionna Mendoza
A single administration of mebufotenin benzoate nasal spray produced rapid, sustained reductions in depressive symptoms among adults with TRD, according to a phase 2b trial published in JAMA.
A single administration of mebufotenin benzoate nasal spray produced rapid, sustained reductions in depressive symptoms among adults with TRD, according to a phase 2b trial published in JAMA.
A single administration of...
11/02/2026
Psych Congress Network
A clinician fills out a form on a clipboard
News
RAP-219 Meets Key Endpoints in Acute Bipolar Mania Trial
10/26/2026
Brionna Mendoza
Investigational RAP-219 met the primary and secondary endpoints in a randomized, double-blind, placebo-controlled trial of adults experiencing acute bipolar mania, manufacturer Rapport Therapeutics announced on October 20, 2026.
Investigational RAP-219 met the primary and secondary endpoints in a randomized, double-blind, placebo-controlled trial of adults experiencing acute bipolar mania, manufacturer Rapport Therapeutics announced on October 20, 2026.
Investigational RAP-219 met the...
10/26/2026
Psych Congress Network
3D illustration of a brain in blue and white against a black background
Research Summary
Home Depression Protocol Proves Feasible but Shows No Added Benefit
10/21/2026
Brionna Mendoza
Home transcranial direct current stimulation paired with cognitive training delivered through a video game was feasible but offered no superior antidepressant benefit in a randomized clinical trial published in JAMA Network Open.
Home transcranial direct current stimulation paired with cognitive training delivered through a video game was feasible but offered no superior antidepressant benefit in a randomized clinical trial published in JAMA Network Open.
Home transcranial direct current...
10/21/2026
Psych Congress Network
a woman pours a pill from a pill bottle into her hand
Research Summary
Meta-Analysis Finds No Clear Sex Differences in Antipsychotic Efficacy
10/15/2026
Maria Mantas
An individual participant data meta-analysis of 18 fixed-dose trials involving 7062 adults with acute schizophrenia found no evidence of sex differences in antipsychotic efficacy for overall symptom improvement.
An individual participant data meta-analysis of 18 fixed-dose trials involving 7062 adults with acute schizophrenia found no evidence of sex differences in antipsychotic efficacy for overall symptom improvement.
An individual participant data...
10/15/2026
Psych Congress Network
Head in profile with brain visible and target over brain
Research Summary
Structural Connectivity–Guided iTBS Improves Early Depression Outcomes
10/08/2026
Brionna Mendoza
A connectivity-guided approach to accelerated iTBS produced greater short-term reductions in depression severity than conventional scalp-based targeting.
A connectivity-guided approach to accelerated iTBS produced greater short-term reductions in depression severity than conventional scalp-based targeting.
A connectivity-guided approach...
10/08/2026
Psych Congress Network
an illustration of a man sitting on the ground holding his head with his profile and brain in the background
Research Summary
Only 19.1% of First-Episode Psychosis Patients Adhere to Antipsychotics
10/06/2026
Brionna Mendoza
Young people beginning antipsychotic treatment after first-episode psychosis had low medication adherence, according to a retrospective US cohort study published in JAMA Network Open.
Young people beginning antipsychotic treatment after first-episode psychosis had low medication adherence, according to a retrospective US cohort study published in JAMA Network Open.
Young people beginning...
10/06/2026
Psych Congress Network
A selection of ultraprocessed foods, including donuts, hamburgers, pizza, and fries.
News
Low-Ultraprocessed-Food Diet Linked to Lower Depression Scores
09/25/2026
Brionna Mendoza
Reducing ultraprocessed food consumption was feasible and acceptable among adults with major depressive disorder (MDD) and was associated with lower depression and anxiety scores.
Reducing ultraprocessed food consumption was feasible and acceptable among adults with major depressive disorder (MDD) and was associated with lower depression and anxiety scores.
Reducing ultraprocessed food...
09/25/2026
Psych Congress Network
older woman with depression
Research Summary
Vortioxetine Improves Depression, Shows Mixed Cognitive Effects in Older Adults
09/23/2026
Maria Mantas
Vortioxetine was consistently associated with reduced depressive symptoms in older adults with MDD, while its effects on cognition were less consistent, according to a systematic review.
Vortioxetine was consistently associated with reduced depressive symptoms in older adults with MDD, while its effects on cognition were less consistent, according to a systematic review.
Vortioxetine was consistently...
09/23/2026
Psych Congress Network
a woman holds her hands as she looks at her computer screen
Conference Coverage
Semaglutide Linked to Fewer Cognitive Symptoms in Psychiatric Disorders
09/19/2026
Maria Mantas
Semaglutide initiation was associated with fewer clinician-recorded cognitive signs and symptoms among adults with psychiatric disorders, according to a poster presented at Psych Congress.
Semaglutide initiation was associated with fewer clinician-recorded cognitive signs and symptoms among adults with psychiatric disorders, according to a poster presented at Psych Congress.
Semaglutide initiation was...
09/19/2026
Psych Congress Network

NEW FROM PSYCH CONGRESS NP INSTITUTE

Michael Asbach and Arwen Podesta
Clinical Pearls
Making Lifestyle Interventions Practical and Accessible in MDD Care
10/29/2026
Michael Asbach, DMSc, PA-C; Arwen Podesta, MD
Arwen Podesta, MD, DFAPA, Psych Congress Steering Committee Member, and Mike Asbach, DMSc, PA-C, Co-Chair, Psych Congress PA Institute, discuss practical strategies for incorporating nutrition and exercise recommendations into psychiatric...
Arwen Podesta, MD, DFAPA, Psych Congress Steering Committee Member, and Mike Asbach, DMSc, PA-C, Co-Chair, Psych Congress PA Institute, discuss practical strategies for incorporating nutrition and exercise recommendations into psychiatric...
Arwen Podesta, MD, DFAPA, Psych...
10/29/2026
Psych Congress NP Institute
Michael Asbach and Arwen Podesta
Clinical Pearls
Addressing Lifestyle Factors in Major Depressive Disorder
10/23/2026
Michael Asbach, DMSc, PA-C; Arwen Podesta, MD
How can clinicians incorporate lifestyle interventions into major depressive disorder (MDD) treatment alongside pharmacotherapy?
How can clinicians incorporate lifestyle interventions into major depressive disorder (MDD) treatment alongside pharmacotherapy?
How can clinicians incorporate...
10/23/2026
Psych Congress NP Institute
Kristian Dambrino, DNP, PMHNP-BC
Clinical Pearls
Exploring the Role of Dual-Mechanism and Multimodal Antidepressants in MDD Treatment
10/13/2026
Kristian Dambrino, DNP, APRN, MSN
Kristian Dambrino, DNP, PMHNP-BC, explores the role that dual-mechanism and multimodal medications may play in individualized major depressive disorder (MDD) care.
Kristian Dambrino, DNP, PMHNP-BC, explores the role that dual-mechanism and multimodal medications may play in individualized major depressive disorder (MDD) care.
Kristian Dambrino, DNP,...
10/13/2026
Psych Congress NP Institute

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