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Ankylosing Spondylitis

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News
Opioid Use Associated With Fractures in People With Ankylosing Spondylitis
12/20/2023
Lisa Kuhns, PhD, MD
Increasing age, historical fracture, and opioid use are associated with higher odds of fracture in ankylosing spondylitis (AS), according to a study published in Arthritis Care & Research. “We performed a retrospective cohort study...
Increasing age, historical fracture, and opioid use are associated with higher odds of fracture in ankylosing spondylitis (AS), according to a study published in Arthritis Care & Research. “We performed a retrospective cohort study...
Increasing age, historical...
12/20/2023
First Report Managed Care
News
Analysis Finds Similar Safety Profile with Upadacitinib Across Conditions
11/03/2023
Jolynn Tumolo
The Janus kinase (JAK) inhibitor upadacitinib offers a similar long-term safety profile across rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and atopic dermatitis (AD) despite some variations in adverse...
The Janus kinase (JAK) inhibitor upadacitinib offers a similar long-term safety profile across rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and atopic dermatitis (AD) despite some variations in adverse...
The Janus kinase (JAK) inhibitor...
11/03/2023
First Report Managed Care
News
High Rates of Depression, Anxiety in Patients With Ankylosing Spondylitis
10/06/2023
Jolynn Tumolo
Half of patients with ankylosing spondylitis had clinically significant depression, and more than a third had clinically significant anxiety, according to a single-center, cross-sectional study currently underway.
Half of patients with ankylosing spondylitis had clinically significant depression, and more than a third had clinically significant anxiety, according to a single-center, cross-sectional study currently underway.
Half of patients with ankylosing...
10/06/2023
First Report Managed Care
News
Achieving Disease Control in PsA, AS Associated with Lower Medical Costs
09/15/2023
Jolynn Tumolo
A study published in Rheumatology and Therapy found that individuals diagnosed with psoriatic arthritis (PsA) or ankylosing spondylitis (AS) and exhibiting lower levels of disease activity incurred reduced healthcare resource utilization and...
A study published in Rheumatology and Therapy found that individuals diagnosed with psoriatic arthritis (PsA) or ankylosing spondylitis (AS) and exhibiting lower levels of disease activity incurred reduced healthcare resource utilization and...
A study published in...
09/15/2023
First Report Managed Care
News
Can Tumor Necrosis Factor Inhibitors Reduce the Risk of Fractures in AS Patients?
08/30/2023
Danielle Sposato
Researchers sought to understand if fracture risk decreased among individuals with ankylosing spondylitis with tumor necrosis factor inhibitors treatments compared to non-AS patients.
Researchers sought to understand if fracture risk decreased among individuals with ankylosing spondylitis with tumor necrosis factor inhibitors treatments compared to non-AS patients.
Researchers sought to understand...
08/30/2023
First Report Managed Care
News
Fear of Movement in Patients With Ankylosing Spondylitis Linked With Lower Life Quality
07/27/2023
Jolynn Tumolo
Research findings indicate a link between kinesiophobia, a fear of movement and injury, and decreased quality of life in patients with ankylosing spondylitis.
Research findings indicate a link between kinesiophobia, a fear of movement and injury, and decreased quality of life in patients with ankylosing spondylitis.
Research findings indicate a...
07/27/2023
First Report Managed Care
News
Tildrakizumab No Better Than Placebo for Ankylosing Spondylitis
06/09/2023
Jolynn Tumolo
A 48-week trial of tildrakizumab in patients with ankylosing spondylitis was terminated early after researchers found that the drug had no efficacy in comparison to placebo.
A 48-week trial of tildrakizumab in patients with ankylosing spondylitis was terminated early after researchers found that the drug had no efficacy in comparison to placebo.
A 48-week trial of tildrakizumab...
06/09/2023
First Report Managed Care
News
Risk of Psychiatric Comorbidity Higher in Patients With Ankylosing Spondylitis
05/19/2023
Jolynn Tumolo
Findings from a population-based, cross-sectional study suggest that patients with ankylosing spondylitis are at a higher risk of developing psychiatric disorders.
Findings from a population-based, cross-sectional study suggest that patients with ankylosing spondylitis are at a higher risk of developing psychiatric disorders.
Findings from a...
05/19/2023
First Report Managed Care
News
Short-term Biosimilar Adalimumab Provides Long-term Relief for Ankylosing Spondylitis
04/14/2023
Jolynn Tumolo
Treatment with biosimilar adalimumab was associated with a significant improvement in ankylosing spondylitis symptoms for up to 1 year, according to new findings.
Treatment with biosimilar adalimumab was associated with a significant improvement in ankylosing spondylitis symptoms for up to 1 year, according to new findings.
Treatment with biosimilar...
04/14/2023
First Report Managed Care
News
JAK Inhibitor Improves Slate of Patient-Reported Outcomes in Biologic Refractory Ankylosing Spondylitis
03/28/2023
Jolynn Tumolo
Researchers studied a JAK inhibitor's efficacy for improving disease activity, health-related quality of life, and other measures in a cohort of patients with ankylosing spondylitis who did not respond or tolerate biologics.
Researchers studied a JAK inhibitor's efficacy for improving disease activity, health-related quality of life, and other measures in a cohort of patients with ankylosing spondylitis who did not respond or tolerate biologics.
Researchers studied a JAK...
03/28/2023
First Report Managed Care
News
Baseline Variables Predict Probability of Initial Response to TNFi Inhibitors in Patients With AS
10/27/2022
Edan Stanley
Researchers sought to develop models of the probability of short-term response to tumor necrosis factor inhibitor treatment in patients with ankylosing spondylitis.
Researchers sought to develop models of the probability of short-term response to tumor necrosis factor inhibitor treatment in patients with ankylosing spondylitis.
Researchers sought to develop...
10/27/2022
First Report Managed Care

Newsfeed

News
Opioid Use Associated With Fractures in People With Ankylosing Spondylitis
12/20/2023
Lisa Kuhns, PhD, MD
Increasing age, historical fracture, and opioid use are associated with higher odds of fracture in ankylosing spondylitis (AS), according to a study published in Arthritis Care & Research. “We performed a retrospective cohort study...
Increasing age, historical fracture, and opioid use are associated with higher odds of fracture in ankylosing spondylitis (AS), according to a study published in Arthritis Care & Research. “We performed a retrospective cohort study...
Increasing age, historical...
12/20/2023
First Report Managed Care
News
Analysis Finds Similar Safety Profile with Upadacitinib Across Conditions
11/03/2023
Jolynn Tumolo
The Janus kinase (JAK) inhibitor upadacitinib offers a similar long-term safety profile across rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and atopic dermatitis (AD) despite some variations in adverse...
The Janus kinase (JAK) inhibitor upadacitinib offers a similar long-term safety profile across rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and atopic dermatitis (AD) despite some variations in adverse...
The Janus kinase (JAK) inhibitor...
11/03/2023
First Report Managed Care
News
High Rates of Depression, Anxiety in Patients With Ankylosing Spondylitis
10/06/2023
Jolynn Tumolo
Half of patients with ankylosing spondylitis had clinically significant depression, and more than a third had clinically significant anxiety, according to a single-center, cross-sectional study currently underway.
Half of patients with ankylosing spondylitis had clinically significant depression, and more than a third had clinically significant anxiety, according to a single-center, cross-sectional study currently underway.
Half of patients with ankylosing...
10/06/2023
First Report Managed Care
News
Achieving Disease Control in PsA, AS Associated with Lower Medical Costs
09/15/2023
Jolynn Tumolo
A study published in Rheumatology and Therapy found that individuals diagnosed with psoriatic arthritis (PsA) or ankylosing spondylitis (AS) and exhibiting lower levels of disease activity incurred reduced healthcare resource utilization and...
A study published in Rheumatology and Therapy found that individuals diagnosed with psoriatic arthritis (PsA) or ankylosing spondylitis (AS) and exhibiting lower levels of disease activity incurred reduced healthcare resource utilization and...
A study published in...
09/15/2023
First Report Managed Care
News
Can Tumor Necrosis Factor Inhibitors Reduce the Risk of Fractures in AS Patients?
08/30/2023
Danielle Sposato
Researchers sought to understand if fracture risk decreased among individuals with ankylosing spondylitis with tumor necrosis factor inhibitors treatments compared to non-AS patients.
Researchers sought to understand if fracture risk decreased among individuals with ankylosing spondylitis with tumor necrosis factor inhibitors treatments compared to non-AS patients.
Researchers sought to understand...
08/30/2023
First Report Managed Care
News
Fear of Movement in Patients With Ankylosing Spondylitis Linked With Lower Life Quality
07/27/2023
Jolynn Tumolo
Research findings indicate a link between kinesiophobia, a fear of movement and injury, and decreased quality of life in patients with ankylosing spondylitis.
Research findings indicate a link between kinesiophobia, a fear of movement and injury, and decreased quality of life in patients with ankylosing spondylitis.
Research findings indicate a...
07/27/2023
First Report Managed Care
News
Tildrakizumab No Better Than Placebo for Ankylosing Spondylitis
06/09/2023
Jolynn Tumolo
A 48-week trial of tildrakizumab in patients with ankylosing spondylitis was terminated early after researchers found that the drug had no efficacy in comparison to placebo.
A 48-week trial of tildrakizumab in patients with ankylosing spondylitis was terminated early after researchers found that the drug had no efficacy in comparison to placebo.
A 48-week trial of tildrakizumab...
06/09/2023
First Report Managed Care
News
Risk of Psychiatric Comorbidity Higher in Patients With Ankylosing Spondylitis
05/19/2023
Jolynn Tumolo
Findings from a population-based, cross-sectional study suggest that patients with ankylosing spondylitis are at a higher risk of developing psychiatric disorders.
Findings from a population-based, cross-sectional study suggest that patients with ankylosing spondylitis are at a higher risk of developing psychiatric disorders.
Findings from a...
05/19/2023
First Report Managed Care
News
Short-term Biosimilar Adalimumab Provides Long-term Relief for Ankylosing Spondylitis
04/14/2023
Jolynn Tumolo
Treatment with biosimilar adalimumab was associated with a significant improvement in ankylosing spondylitis symptoms for up to 1 year, according to new findings.
Treatment with biosimilar adalimumab was associated with a significant improvement in ankylosing spondylitis symptoms for up to 1 year, according to new findings.
Treatment with biosimilar...
04/14/2023
First Report Managed Care
News
JAK Inhibitor Improves Slate of Patient-Reported Outcomes in Biologic Refractory Ankylosing Spondylitis
03/28/2023
Jolynn Tumolo
Researchers studied a JAK inhibitor's efficacy for improving disease activity, health-related quality of life, and other measures in a cohort of patients with ankylosing spondylitis who did not respond or tolerate biologics.
Researchers studied a JAK inhibitor's efficacy for improving disease activity, health-related quality of life, and other measures in a cohort of patients with ankylosing spondylitis who did not respond or tolerate biologics.
Researchers studied a JAK...
03/28/2023
First Report Managed Care
Behind the Bill
CMS Expands Oversight and Competition Among Organ Procurement Organizations
11/06/2026
Grace Taylor, MS, MA
New Centers for Medicare & Medicaid Services (CMS) requirements address organ procurement safety, performance measurement, and service-area transitions, with implications for transplant access and care coordination.
New Centers for Medicare & Medicaid Services (CMS) requirements address organ procurement safety, performance measurement, and service-area transitions, with implications for transplant access and care coordination.
New Centers for Medicare &...
11/06/2026
First Report Managed Care
News
MASH Treatment Model Projects Significant Economic Wastage With Low Semaglutide Persistence
11/06/2026
Rebecca Amrick
A study presented at AASLD TLM 2026 found that low adherence to optimal-dose semaglutide among patients with metabolic dysfunction-associated steatohepatitis (MASH) was projected to contribute to significant excess medical and pharmacy costs...
A study presented at AASLD TLM 2026 found that low adherence to optimal-dose semaglutide among patients with metabolic dysfunction-associated steatohepatitis (MASH) was projected to contribute to significant excess medical and pharmacy costs...
A study presented at AASLD TLM...
11/06/2026
First Report Managed Care
News
MASH Disease Progression Associated With Increased Economic Burden Among Medicare Beneficiaries
11/04/2026
Rebecca Amrick
A study of Medicare fee-for-service beneficiaries found that those with metabolic dysfunction-associated steatohepatitis (MASH) had higher health care utilization rates and medical costs compared to those without MASH, with the greatest...
A study of Medicare fee-for-service beneficiaries found that those with metabolic dysfunction-associated steatohepatitis (MASH) had higher health care utilization rates and medical costs compared to those without MASH, with the greatest...
A study of Medicare...
11/04/2026
First Report Managed Care
News
Real-World Evidence Highlights Broader Benefits of Omalizumab for Food Allergy Management
11/03/2026
Hannah Musick
A narrative review of real-world evidence suggests that omalizumab may improve food allergy management beyond preventing allergic reactions, with potential benefits for dietary flexibility, quality of life, and patients with complex allergic...
A narrative review of real-world evidence suggests that omalizumab may improve food allergy management beyond preventing allergic reactions, with potential benefits for dietary flexibility, quality of life, and patients with complex allergic...
A narrative review of real-world...
11/03/2026
First Report Managed Care
News
Direct Patient and Caregiver Engagement in Prior Authorization Linked to Care Delays
11/03/2026
Rebecca Amrick
Researchers found that direct patient and caregiver involvement in prior authorization procedures was associated with delayed or suboptimal care, highlighting the need for policy reform to reduce administrative burdens and improve access to...
Researchers found that direct patient and caregiver involvement in prior authorization procedures was associated with delayed or suboptimal care, highlighting the need for policy reform to reduce administrative burdens and improve access to...
Researchers found that direct...
11/03/2026
First Report Managed Care
Behind the Bill
HHS HTI-5 Final Rule Cuts Health IT Requirements With $1.5 Billion in Projected Savings
10/30/2026
Grace Taylor, MS, MA
The US Department of Health and Human Services’ (HHS) Health Data, Technology, and Interoperability (HTI-5) final rule reduces health IT certification requirements and projects substantial regulatory savings while leaving proposed...
The US Department of Health and Human Services’ (HHS) Health Data, Technology, and Interoperability (HTI-5) final rule reduces health IT certification requirements and projects substantial regulatory savings while leaving proposed...
The US Department of Health and...
10/30/2026
First Report Managed Care
News
Suboptimal TKI Adherence Across Payer Types Among Patients With CML
10/30/2026
Rebecca Amrick
A comparison of insurance types showed that tyrosine kinase inhibitor (TKI) approval for patients with chronic myeloid leukemia (CML) was higher among Medicare and Medicaid beneficiaries, but treatment adherence remained suboptimal across...
A comparison of insurance types showed that tyrosine kinase inhibitor (TKI) approval for patients with chronic myeloid leukemia (CML) was higher among Medicare and Medicaid beneficiaries, but treatment adherence remained suboptimal across...
A comparison of insurance types...
10/30/2026
First Report Managed Care
News
Real-World Study Reveals Shifting Treatment Patterns and Persistent Unmet Needs in DLBCL
10/29/2026
Hannah Musick
A real-world US study found that novel therapies are increasingly replacing conventional treatments for diffuse large B-cell lymphoma (DLBCL), although declining survival outcomes across successive lines of therapy and substantial variation...
A real-world US study found that novel therapies are increasingly replacing conventional treatments for diffuse large B-cell lymphoma (DLBCL), although declining survival outcomes across successive lines of therapy and substantial variation...
A real-world US study found that...
10/29/2026
First Report Managed Care
News
Inadequate Hematocrit Control in Polycythemia Vera Linked to High Health Care Burden
10/29/2026
Grace Taylor, MS, MA
A US claims study found that patients with polycythemia vera frequently experienced inadequate hematocrit control despite treatment, with thromboembolic events contributing to substantial health care costs.
A US claims study found that patients with polycythemia vera frequently experienced inadequate hematocrit control despite treatment, with thromboembolic events contributing to substantial health care costs.
A US claims study found that...
10/29/2026
First Report Managed Care
News
MA Associated With Less Expensive Cancer Therapies but Similar Treatment Utilization Compared to TM
10/28/2026
Rebecca Amrick
Researchers found that while Medicare Advantage (MA) is associated with lower-cost cancer treatments, beneficiaries had a similar likelihood of initiating optimal treatments for cancer type as those enrolled in traditional Medicare (TM).
Researchers found that while Medicare Advantage (MA) is associated with lower-cost cancer treatments, beneficiaries had a similar likelihood of initiating optimal treatments for cancer type as those enrolled in traditional Medicare (TM).
Researchers found that while...
10/28/2026
First Report Managed Care

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