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Chronic Myeloid Leukemia

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News
10/23/2026
Rebecca Amrick
Through interviews with oncology practice managers, researchers estimated the additional time and costs associated with treatment intolerance among patients with chronic myeloid leukemia (CML), identifying key areas for reducing the...
Through interviews with oncology practice managers, researchers estimated the additional time and costs associated with treatment intolerance among patients with chronic myeloid leukemia (CML), identifying key areas for reducing the...
Through interviews with oncology...
10/23/2026
First Report Managed Care
News
10/20/2026
Rebecca Amrick
Researchers found that patients with chronic myeloid leukemia (CML) from underserved populations had worse outcomes, likely resulting from increased comorbidities and financial barriers, highlighting the need for additional research to...
Researchers found that patients with chronic myeloid leukemia (CML) from underserved populations had worse outcomes, likely resulting from increased comorbidities and financial barriers, highlighting the need for additional research to...
Researchers found that patients...
10/20/2026
First Report Managed Care
News
10/16/2026
Rebecca Amrick
Researchers found that tyrosine kinase inhibitor (TKI)-related adverse events were associated with decreased quality of life and increased activity impairment among patients with chronic myeloid leukemia (CML).
Researchers found that tyrosine kinase inhibitor (TKI)-related adverse events were associated with decreased quality of life and increased activity impairment among patients with chronic myeloid leukemia (CML).
Researchers found that tyrosine...
10/16/2026
First Report Managed Care
News
10/09/2026
Rebecca Amrick
Researchers found that asciminib 200 mg twice daily demonstrated significant efficacy and manageable toxicity among patients with T315I-mutated chronic myeloid leukemia in chronic phase (CML-CP).
Researchers found that asciminib 200 mg twice daily demonstrated significant efficacy and manageable toxicity among patients with T315I-mutated chronic myeloid leukemia in chronic phase (CML-CP).
Researchers found that asciminib...
10/09/2026
First Report Managed Care
News
09/21/2026
Hannah Musick
A 50-gene transcriptomic signature predicted the likelihood of sustained treatment-free remission after tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia, potentially supporting more individualized treatment...
A 50-gene transcriptomic signature predicted the likelihood of sustained treatment-free remission after tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia, potentially supporting more individualized treatment...
A 50-gene transcriptomic...
09/21/2026
First Report Managed Care
News
09/14/2026
Rebecca Amrick
Among patients with CML who discontinued TKI therapy, sustained deep molecular response, lower Sokal scores, and longer treatment duration were associated with a greater likelihood of maintaining treatment-free remission.
Among patients with CML who discontinued TKI therapy, sustained deep molecular response, lower Sokal scores, and longer treatment duration were associated with a greater likelihood of maintaining treatment-free remission.
Among patients with CML who...
09/14/2026
First Report Managed Care
News
09/03/2026
Rebecca Amrick
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that...
09/03/2026
First Report Managed Care
News
08/24/2026
Grace Taylor, MS, MA
Long-term tyrosine kinase inhibitors (TKI) therapy has transformed chronic myeloid leukemia (CML) survival, but new findings suggest survivors may continue to experience substantial challenges with overall health, physical function, and...
Long-term tyrosine kinase inhibitors (TKI) therapy has transformed chronic myeloid leukemia (CML) survival, but new findings suggest survivors may continue to experience substantial challenges with overall health, physical function, and...
Long-term tyrosine kinase...
08/24/2026
First Report Managed Care
News
08/19/2026
Hannah Musick
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic...
08/19/2026
First Report Managed Care
News
08/12/2026
Hannah Musick
A new economic analysis suggests that insured patients with chronic myeloid leukemia (CML) may face similar annual out-of-pocket costs across tyrosine kinase inhibitor options, despite substantially higher treatment costs for many...
A new economic analysis suggests that insured patients with chronic myeloid leukemia (CML) may face similar annual out-of-pocket costs across tyrosine kinase inhibitor options, despite substantially higher treatment costs for many...
A new economic analysis suggests...
08/12/2026
First Report Managed Care
News
07/20/2026
Grace Taylor, MS, MA
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine...
07/20/2026
First Report Managed Care

Newsfeed

News
10/23/2026
Rebecca Amrick
Through interviews with oncology practice managers, researchers estimated the additional time and costs associated with treatment intolerance among patients with chronic myeloid leukemia (CML), identifying key areas for reducing the...
Through interviews with oncology practice managers, researchers estimated the additional time and costs associated with treatment intolerance among patients with chronic myeloid leukemia (CML), identifying key areas for reducing the...
Through interviews with oncology...
10/23/2026
First Report Managed Care
News
10/16/2026
Rebecca Amrick
Researchers found that tyrosine kinase inhibitor (TKI)-related adverse events were associated with decreased quality of life and increased activity impairment among patients with chronic myeloid leukemia (CML).
Researchers found that tyrosine kinase inhibitor (TKI)-related adverse events were associated with decreased quality of life and increased activity impairment among patients with chronic myeloid leukemia (CML).
Researchers found that tyrosine...
10/16/2026
First Report Managed Care
News
10/09/2026
Rebecca Amrick
Researchers found that asciminib 200 mg twice daily demonstrated significant efficacy and manageable toxicity among patients with T315I-mutated chronic myeloid leukemia in chronic phase (CML-CP).
Researchers found that asciminib 200 mg twice daily demonstrated significant efficacy and manageable toxicity among patients with T315I-mutated chronic myeloid leukemia in chronic phase (CML-CP).
Researchers found that asciminib...
10/09/2026
First Report Managed Care
News
09/21/2026
Hannah Musick
A 50-gene transcriptomic signature predicted the likelihood of sustained treatment-free remission after tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia, potentially supporting more individualized treatment...
A 50-gene transcriptomic signature predicted the likelihood of sustained treatment-free remission after tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia, potentially supporting more individualized treatment...
A 50-gene transcriptomic...
09/21/2026
First Report Managed Care
News
09/14/2026
Rebecca Amrick
Among patients with CML who discontinued TKI therapy, sustained deep molecular response, lower Sokal scores, and longer treatment duration were associated with a greater likelihood of maintaining treatment-free remission.
Among patients with CML who discontinued TKI therapy, sustained deep molecular response, lower Sokal scores, and longer treatment duration were associated with a greater likelihood of maintaining treatment-free remission.
Among patients with CML who...
09/14/2026
First Report Managed Care
News
09/03/2026
Rebecca Amrick
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that...
09/03/2026
First Report Managed Care
News
08/19/2026
Hannah Musick
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic...
08/19/2026
First Report Managed Care
News
07/20/2026
Grace Taylor, MS, MA
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine...
07/20/2026
First Report Managed Care
News
07/20/2026
Rebecca Amrick
Cavhanza (nilotinib) has been approved by the US Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), increasing treatment options for CML and possibly improving patient...
Cavhanza (nilotinib) has been approved by the US Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), increasing treatment options for CML and possibly improving patient...
Cavhanza (nilotinib) has been...
07/20/2026
First Report Managed Care
News
07/16/2026
Hannah Musick
A systematic review found that combining tyrosine kinase inhibitors with anticoagulants was generally associated with a low incidence of bleeding and thrombotic events in chronic myeloid leukemia, although patients with renal impairment,...
A systematic review found that combining tyrosine kinase inhibitors with anticoagulants was generally associated with a low incidence of bleeding and thrombotic events in chronic myeloid leukemia, although patients with renal impairment,...
A systematic review found that...
07/16/2026
First Report Managed Care
Behind the Bill
10/23/2026
Grace Taylor, MS, MA
The US Department of Justice (DOJ) and Department of Health and Human Services (HHS) have introduced a 6-month pilot program allowing eligible health care organizations to voluntarily disclose potential False Claims Act violations in exchange...
The US Department of Justice (DOJ) and Department of Health and Human Services (HHS) have introduced a 6-month pilot program allowing eligible health care organizations to voluntarily disclose potential False Claims Act violations in exchange...
The US Department of Justice...
10/23/2026
First Report Managed Care
News
10/23/2026
Rebecca Amrick
Through interviews with oncology practice managers, researchers estimated the additional time and costs associated with treatment intolerance among patients with chronic myeloid leukemia (CML), identifying key areas for reducing the...
Through interviews with oncology practice managers, researchers estimated the additional time and costs associated with treatment intolerance among patients with chronic myeloid leukemia (CML), identifying key areas for reducing the...
Through interviews with oncology...
10/23/2026
First Report Managed Care
News
10/22/2026
Rebecca Amrick
Researchers found that the investigational biosimilar ADL-018 demonstrated pharmacokinetic equivalence and a comparable safety profile to reference omalizumab in healthy participants, supporting its potential as a future therapeutic...
Researchers found that the investigational biosimilar ADL-018 demonstrated pharmacokinetic equivalence and a comparable safety profile to reference omalizumab in healthy participants, supporting its potential as a future therapeutic...
Researchers found that the...
10/22/2026
First Report Managed Care
News
10/21/2026
Rebecca Amrick
Researchers found that among patients with moderate to severe atopic dermatitis (AD), those who switched to second-line therapies had higher utilization rates and care costs compared to those who remained on first-line treatments.
Researchers found that among patients with moderate to severe atopic dermatitis (AD), those who switched to second-line therapies had higher utilization rates and care costs compared to those who remained on first-line treatments.
Researchers found that among...
10/21/2026
First Report Managed Care
News
10/19/2026
Rebecca Amrick
Across Medicare Advantage (MA) plans, researchers found that more socially vulnerable counties had higher rates of prior authorization (PA) and more restrictive policies than less vulnerable counties, illustrating increased disparities among...
Across Medicare Advantage (MA) plans, researchers found that more socially vulnerable counties had higher rates of prior authorization (PA) and more restrictive policies than less vulnerable counties, illustrating increased disparities among...
Across Medicare Advantage (MA)...
10/19/2026
First Report Managed Care
News
10/19/2026
Rebecca Amrick
Researchers described the prevalence and incidence of secondary malignancies among adults with polycythemia vera (PV), identifying vulnerable patients with a higher risk of disease transformation and secondary cancers.
Researchers described the prevalence and incidence of secondary malignancies among adults with polycythemia vera (PV), identifying vulnerable patients with a higher risk of disease transformation and secondary cancers.
Researchers described the...
10/19/2026
First Report Managed Care
Behind the Bill
10/16/2026
Grace Taylor, MS, MA
The US Department of Justice’s (DOJ) new health care fraud self-disclosure policy simplifies reporting as broader enforcement priorities put corporate compliance practices in focus.
The US Department of Justice’s (DOJ) new health care fraud self-disclosure policy simplifies reporting as broader enforcement priorities put corporate compliance practices in focus.
The US Department of Justice’s...
10/16/2026
First Report Managed Care
News
10/16/2026
Rebecca Amrick
Researchers found that tyrosine kinase inhibitor (TKI)-related adverse events were associated with decreased quality of life and increased activity impairment among patients with chronic myeloid leukemia (CML).
Researchers found that tyrosine kinase inhibitor (TKI)-related adverse events were associated with decreased quality of life and increased activity impairment among patients with chronic myeloid leukemia (CML).
Researchers found that tyrosine...
10/16/2026
First Report Managed Care
News
10/15/2026
Hannah Musick
A real-world US study found that patients with moderate-to-severe atopic dermatitis experiencing both severe itch and severe skin lesions incurred the highest annual health care charges, highlighting the importance of assessing both symptom...
A real-world US study found that patients with moderate-to-severe atopic dermatitis experiencing both severe itch and severe skin lesions incurred the highest annual health care charges, highlighting the importance of assessing both symptom...
A real-world US study found that...
10/15/2026
First Report Managed Care
News
10/15/2026
Rebecca Amrick
A cost-effectiveness model found semaglutide 2.4 mg to be a clinically beneficial and economically viable treatment option for patients with non-cirrhotic metabolic dysfunction‐associated steatohepatitis (MASH) with moderate to advanced...
A cost-effectiveness model found semaglutide 2.4 mg to be a clinically beneficial and economically viable treatment option for patients with non-cirrhotic metabolic dysfunction‐associated steatohepatitis (MASH) with moderate to advanced...
A cost-effectiveness model found...
10/15/2026
First Report Managed Care