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Chronic Myeloid Leukemia

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News
09/03/2026
Rebecca Amrick
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that...
09/03/2026
First Report Managed Care
News
08/24/2026
Grace Taylor, MS, MA
Long-term tyrosine kinase inhibitors (TKI) therapy has transformed chronic myeloid leukemia (CML) survival, but new findings suggest survivors may continue to experience substantial challenges with overall health, physical function, and...
Long-term tyrosine kinase inhibitors (TKI) therapy has transformed chronic myeloid leukemia (CML) survival, but new findings suggest survivors may continue to experience substantial challenges with overall health, physical function, and...
Long-term tyrosine kinase...
08/24/2026
First Report Managed Care
News
08/19/2026
Hannah Musick
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic...
08/19/2026
First Report Managed Care
News
08/12/2026
Hannah Musick
A new economic analysis suggests that insured patients with chronic myeloid leukemia (CML) may face similar annual out-of-pocket costs across tyrosine kinase inhibitor options, despite substantially higher treatment costs for many...
A new economic analysis suggests that insured patients with chronic myeloid leukemia (CML) may face similar annual out-of-pocket costs across tyrosine kinase inhibitor options, despite substantially higher treatment costs for many...
A new economic analysis suggests...
08/12/2026
First Report Managed Care
News
07/20/2026
Grace Taylor, MS, MA
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine...
07/20/2026
First Report Managed Care
News
07/20/2026
Rebecca Amrick
Cavhanza (nilotinib) has been approved by the US Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), increasing treatment options for CML and possibly improving patient...
Cavhanza (nilotinib) has been approved by the US Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), increasing treatment options for CML and possibly improving patient...
Cavhanza (nilotinib) has been...
07/20/2026
First Report Managed Care
News
07/16/2026
Hannah Musick
A systematic review found that combining tyrosine kinase inhibitors with anticoagulants was generally associated with a low incidence of bleeding and thrombotic events in chronic myeloid leukemia, although patients with renal impairment,...
A systematic review found that combining tyrosine kinase inhibitors with anticoagulants was generally associated with a low incidence of bleeding and thrombotic events in chronic myeloid leukemia, although patients with renal impairment,...
A systematic review found that...
07/16/2026
First Report Managed Care
News
07/08/2026
Grace Taylor, MS, MA
A meta-analysis of 16 studies found that approximately half of patients with chronic-phase chronic myeloid leukemia (CML) remained in treatment-free remission for up to 36 months after discontinuing tyrosine kinase inhibitor (TKI) therapy,...
A meta-analysis of 16 studies found that approximately half of patients with chronic-phase chronic myeloid leukemia (CML) remained in treatment-free remission for up to 36 months after discontinuing tyrosine kinase inhibitor (TKI) therapy,...
A meta-analysis of 16 studies...
07/08/2026
First Report Managed Care
News
06/18/2026
Hannah Musick
Food restrictions associated with certain chronic myeloid leukemia therapies were linked to greater treatment burden, missed doses, and adherence challenges, with more than half of surveyed patients expressing interest in a treatment option...
Food restrictions associated with certain chronic myeloid leukemia therapies were linked to greater treatment burden, missed doses, and adherence challenges, with more than half of surveyed patients expressing interest in a treatment option...
Food restrictions associated...
06/18/2026
First Report Managed Care
News
06/08/2026
Grace Taylor, MS, MA
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with...
06/08/2026
First Report Managed Care
News
05/20/2026
Hannah Musick
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib...
05/20/2026
First Report Managed Care

Newsfeed

News
09/03/2026
Rebecca Amrick
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that...
09/03/2026
First Report Managed Care
News
08/19/2026
Hannah Musick
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic myeloid leukemia are expanding treatment options and supporting a more individualized approach that balances molecular response, toxicity, treatment-free remission goals, comorbidities, and cost.
Recent advances in chronic...
08/19/2026
First Report Managed Care
News
07/20/2026
Grace Taylor, MS, MA
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine kinase inhibitor (TKI) dose de-escalation preserved treatment-free remission while reducing adverse events in adults with chronic myeloid leukemia (CML).
A study found that tyrosine...
07/20/2026
First Report Managed Care
News
07/20/2026
Rebecca Amrick
Cavhanza (nilotinib) has been approved by the US Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), increasing treatment options for CML and possibly improving patient...
Cavhanza (nilotinib) has been approved by the US Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), increasing treatment options for CML and possibly improving patient...
Cavhanza (nilotinib) has been...
07/20/2026
First Report Managed Care
News
07/16/2026
Hannah Musick
A systematic review found that combining tyrosine kinase inhibitors with anticoagulants was generally associated with a low incidence of bleeding and thrombotic events in chronic myeloid leukemia, although patients with renal impairment,...
A systematic review found that combining tyrosine kinase inhibitors with anticoagulants was generally associated with a low incidence of bleeding and thrombotic events in chronic myeloid leukemia, although patients with renal impairment,...
A systematic review found that...
07/16/2026
First Report Managed Care
News
07/08/2026
Grace Taylor, MS, MA
A meta-analysis of 16 studies found that approximately half of patients with chronic-phase chronic myeloid leukemia (CML) remained in treatment-free remission for up to 36 months after discontinuing tyrosine kinase inhibitor (TKI) therapy,...
A meta-analysis of 16 studies found that approximately half of patients with chronic-phase chronic myeloid leukemia (CML) remained in treatment-free remission for up to 36 months after discontinuing tyrosine kinase inhibitor (TKI) therapy,...
A meta-analysis of 16 studies...
07/08/2026
First Report Managed Care
News
06/08/2026
Grace Taylor, MS, MA
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with...
06/08/2026
First Report Managed Care
News
05/20/2026
Hannah Musick
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib...
05/20/2026
First Report Managed Care
News
12/28/2021
Jolynn Tumolo
Generic versions of imatinib were comparable in bioequivalence and bioavailability to the branded drug across studies, according to recent findings.
Generic versions of imatinib were comparable in bioequivalence and bioavailability to the branded drug across studies, according to recent findings.
Generic versions of imatinib...
12/28/2021
First Report Managed Care
News
12/07/2021
Jolynn Tumolo
Among patients with chronic myeloid leukemia who had already been treated with at least two tyrosine kinase inhibitors, asciminib resulted in greater major molecular response than bosutinib.
Among patients with chronic myeloid leukemia who had already been treated with at least two tyrosine kinase inhibitors, asciminib resulted in greater major molecular response than bosutinib.
Among patients with chronic...
12/07/2021
First Report Managed Care
News
09/10/2026
Rebecca Amrick
A survey of patients with relapsed or refractory follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) found lower time burden with fixed-duration bispecific antibody regimens, highlighting patient convenience as a crucial factor...
A survey of patients with relapsed or refractory follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) found lower time burden with fixed-duration bispecific antibody regimens, highlighting patient convenience as a crucial factor...
A survey of patients with...
09/10/2026
First Report Managed Care
News
09/08/2026
Rebecca Amrick
Researchers found that newer obesity medications were associated with higher drug and total care costs as well as nonsignificant changes in health care utilization compared to phentermine, raising concerns about access for patients with...
Researchers found that newer obesity medications were associated with higher drug and total care costs as well as nonsignificant changes in health care utilization compared to phentermine, raising concerns about access for patients with...
Researchers found that newer...
09/08/2026
First Report Managed Care
Behind the Bill
09/03/2026
Grace Taylor, MS, MA
The Trump Administration’s agreements with 9 additional drugmakers expand most-favored-nation pricing commitments, potentially lowering prescription drug costs for state Medicaid programs.
The Trump Administration’s agreements with 9 additional drugmakers expand most-favored-nation pricing commitments, potentially lowering prescription drug costs for state Medicaid programs.
The Trump Administration’s...
09/03/2026
First Report Managed Care
News
09/03/2026
Rebecca Amrick
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that asciminib demonstrated comparable efficacy across dosing regimens in patients with pretreated chronic myeloid leukemia in chronic phase (CML-CP), supporting its potential role as a treatment option for patients...
The ASC4OPT study found that...
09/03/2026
First Report Managed Care
News
09/02/2026
Rebecca Amrick
A study found that safety-net providers were more likely to receive medical claim denials than non–safety-net providers, highlighting gaps in coverage that should be addressed in future policy reforms.
A study found that safety-net providers were more likely to receive medical claim denials than non–safety-net providers, highlighting gaps in coverage that should be addressed in future policy reforms.
A study found that safety-net...
09/02/2026
First Report Managed Care
Behind the Bill
08/28/2026
Grace Taylor, MS, MA
The Centers for Medicare & Medicaid Services (CMS) is rolling out Rural Health Transformation Program funding across states, supporting projects aimed at expanding access, modernizing infrastructure, and strengthening rural health care...
The Centers for Medicare & Medicaid Services (CMS) is rolling out Rural Health Transformation Program funding across states, supporting projects aimed at expanding access, modernizing infrastructure, and strengthening rural health care...
The Centers for Medicare &...
08/28/2026
First Report Managed Care
News
08/27/2026
Grace Taylor, MS, MA
Researchers found that posttransplant maintenance therapy for acute myeloid leukemia (AML) was associated with greater health care utilization and higher pharmacy costs, although total health care costs were not significantly increased.
Researchers found that posttransplant maintenance therapy for acute myeloid leukemia (AML) was associated with greater health care utilization and higher pharmacy costs, although total health care costs were not significantly increased.
Researchers found that...
08/27/2026
First Report Managed Care
News
08/27/2026
Rebecca Amrick
Researchers evaluated treatment patterns and care costs among patients with chronic hand eczema, outlining varied disease presentation, extensive use of corticosteroids, and care costs that increase with treatment intensity.
Researchers evaluated treatment patterns and care costs among patients with chronic hand eczema, outlining varied disease presentation, extensive use of corticosteroids, and care costs that increase with treatment intensity.
Researchers evaluated treatment...
08/27/2026
First Report Managed Care
News
08/24/2026
Rebecca Amrick
A study found that among employees with obesity, GLP-1 RA use was associated with higher medical costs but no significant differences in absenteeism or short-term disability days, highlighting the need for further research into their...
A study found that among employees with obesity, GLP-1 RA use was associated with higher medical costs but no significant differences in absenteeism or short-term disability days, highlighting the need for further research into their...
A study found that among...
08/24/2026
First Report Managed Care
News
08/24/2026
Rebecca Amrick
A study found that the Inflation Reduction Act’s cap on out-of-pocket spending among Medicare beneficiaries was associated with increased medication prescriptions and usage, indicating significant improvements in drug access.
A study found that the Inflation Reduction Act’s cap on out-of-pocket spending among Medicare beneficiaries was associated with increased medication prescriptions and usage, indicating significant improvements in drug access.
A study found that the Inflation...
08/24/2026
First Report Managed Care