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Advancing BTK Intervention: Proven Technologies for Patients with CLTI

Michael Siah, MD
Constantino S. Peña, MD, FAHA, FSCCT, FSIR
11/05/2026

In this expert discussion, Drs Michael Sia and Constantino Peña explore the evolving treatment landscape for below-the-knee (BTK) disease in patients with chronic limb-threatening ischemia (CLTI). They discuss the impact of vessel calcification, lessons from the DISRUPT BTK II trial, and how innovations such as Shockwave E8 and Shockwave Javelin Peripheral are helping physicians address complex lesions while improving patient outcomes and quality of life. 

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