Nutraceuticals in Hair Loss: Growing Demand Meets Limited Evidence

Interest in nutraceuticals for hair loss continues to rise, driven by patient demand for “natural” solutions and a rapidly expanding global supplement market, according to Glynis Ablon, MD, FAAD, during her session, “Getting Hairy: ​Evaluating Growth Supplements in Practice.” The session highlighted both the potential role and limitations of supplements in dermatologic practice.

The nutraceutical ingredient market is projected to reach $136.1 billion by 2029, reflecting increased focus on preventive care and functional nutrition. Dr Ablon emphasized that supplements, defined as vitamins, minerals, herbs, amino acids, and other compounds, “should be used as an adjunct to healthy nutrition,” not a replacement.

Hair loss remains highly prevalent, affecting up to 50% of women and a significant proportion of men by midlife. The presentation underscored the importance of addressing nutritional status as a foundational step. “Always start with a nutrition discussion. Nothing beats oral intake of natural vitamins and supplements,” Dr Ablon noted.

Key nutrients linked to hair health include protein, iron, omega-3 fatty acids, and micronutrients like zinc and biotin. Dietary sources, such as fatty fish, eggs, leafy greens, nuts, and seeds, were highlighted for their role in supporting follicular function. Nutritional deficiencies, particularly iron and protein, were identified as contributors to hair loss.

Emerging supplement formulations incorporate multiple ingredients targeting inflammation, oxidative stress, and hormonal pathways. Compounds, such as curcumin, ashwagandha, saw palmetto, and marine collagen, were discussed, along with antioxidants like astaxanthin, described as “the most powerful antioxidant,” with effects on oxidative stress and inflammatory signaling.

Microbiome health was also emphasized, with Dr Ablon noting that it “affects all body disorders, especially skin, hair, and nails.” Strategies aimed at improving gut health and reducing systemic inflammation may indirectly influence hair growth.

Despite growing use, evidence remains limited. Regulatory oversight ensures manufacturing standards, but clinical efficacy data are inconsistent. Dr Ablon emphasized that “evidence for safety and efficacy is limited but improving,” highlighting the need for more rigorous studies with standardized outcomes.

Reference

Ablon G. Getting hairy: ​evaluating growth supplements in practice. Presented at: Music City SCALE Symposium; May 13–17, 2026; Nashville, TN.