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Type 2 Inflammation

Amy paller
Videos
08/01/2026
Amy S. Paller, MD, MS; Riya Gandhi, MA
Dr Amy Paller discusses how advances in understanding type 2 inflammation are transforming pediatric atopic dermatitis care.
Dr Amy Paller discusses how advances in understanding type 2 inflammation are transforming pediatric atopic dermatitis care.
Dr Amy Paller discusses how...
08/01/2026
The Dermatologist
Quiz
06/25/2026
Riya Gandhi, MA
Assess advanced concepts in type 2 inflammatory endotypes, shared therapeutic pathways, and practical treatment approaches in prurigo nodularis.
Assess advanced concepts in type 2 inflammatory endotypes, shared therapeutic pathways, and practical treatment approaches in prurigo nodularis.
Assess advanced concepts in type...
06/25/2026
The Dermatologist
itch
Quiz
06/15/2026
Riya Gandhi, MA
Test your clinical understanding of fibrotic remodeling and the mechanisms underlying persistent itch and chronic disease activity in prurigo nodularis.
Test your clinical understanding of fibrotic remodeling and the mechanisms underlying persistent itch and chronic disease activity in prurigo nodularis.
Test your clinical understanding...
06/15/2026
The Dermatologist
Clinical Insights
06/08/2026
Raj Chovatiya, MD, PhD; Riya Gandhi, MA
Dr Raj Chovatiya explores the neuroimmune mechanisms of this chronic inflammatory disease.
Dr Raj Chovatiya explores the neuroimmune mechanisms of this chronic inflammatory disease.
Dr Raj Chovatiya explores the...
06/08/2026
The Dermatologist
brain
Quiz
06/05/2026
Riya Gandhi, MA
Explore advanced concepts in neuroimmune communication, cytokine-driven itch amplification, and fibrotic signaling pathways involved in prurigo nodularis.
Explore advanced concepts in neuroimmune communication, cytokine-driven itch amplification, and fibrotic signaling pathways involved in prurigo nodularis.
Explore advanced concepts in...
06/05/2026
The Dermatologist
Raj Chovatiya
Videos
05/01/2026
Raj Chovatiya, MD, PhD; Riya Gandhi, MA
Dr Raj Chovatiya explores the neuroimmune mechanisms driving prurigo nodularis, highlighting the role of type 2 inflammation, IL-31–mediated itch signaling, and cytokines like IL-4 and IL-13 in fibrosis and neuronal sensitization.
Dr Raj Chovatiya explores the neuroimmune mechanisms driving prurigo nodularis, highlighting the role of type 2 inflammation, IL-31–mediated itch signaling, and cytokines like IL-4 and IL-13 in fibrosis and neuronal sensitization.
Dr Raj Chovatiya explores the...
05/01/2026
The Dermatologist
Quiz
04/15/2026
Riya Gandhi, MA
Test your expertise in identifying risk factors for persistent pediatric atopic dermatitis and understanding the interplay between barrier dysfunction and immune dysregulation.
Test your expertise in identifying risk factors for persistent pediatric atopic dermatitis and understanding the interplay between barrier dysfunction and immune dysregulation.
Test your expertise in...
04/15/2026
The Dermatologist
Quiz
04/05/2026
Riya Gandhi, MA
Assess advanced clinical reasoning in pediatric atopic dermatitis, including implications of type 2 inflammation for diagnosis, treatment timing, and systemic therapy decisions.
Assess advanced clinical reasoning in pediatric atopic dermatitis, including implications of type 2 inflammation for diagnosis, treatment timing, and systemic therapy decisions.
Assess advanced clinical...
04/05/2026
The Dermatologist
Amy paller
Videos
04/01/2026
Amy S. Paller, MD, MS; Riya Gandhi, MA
Dr Amy Paller discusses how recognizing pediatric atopic dermatitis as a type 2 inflammatory disease has transformed early treatment strategies, enabling safer and more proactive use of targeted therapies.
Dr Amy Paller discusses how recognizing pediatric atopic dermatitis as a type 2 inflammatory disease has transformed early treatment strategies, enabling safer and more proactive use of targeted therapies.
Dr Amy Paller discusses how...
04/01/2026
The Dermatologist
Quiz
03/15/2026
Riya Gandhi, MA
Challenge your understanding of direct and indirect cytokine–nerve interactions and mechanical hypersensitivity of type 2 signaling in prurigo nodularis.
Challenge your understanding of direct and indirect cytokine–nerve interactions and mechanical hypersensitivity of type 2 signaling in prurigo nodularis.
Challenge your understanding of...
03/15/2026
The Dermatologist
Quiz
03/10/2026
Riya Gandhi, MA
Explore the hierarchical and cooperative roles of IL-4, IL-13, and IL-31 in sustaining chronic itch and inflammation in prurigo nodularis.
Explore the hierarchical and cooperative roles of IL-4, IL-13, and IL-31 in sustaining chronic itch and inflammation in prurigo nodularis.
Explore the hierarchical and...
03/10/2026
The Dermatologist

Multimedia

Amy paller
Videos
08/01/2026
Amy S. Paller, MD, MS; Riya Gandhi, MA
Dr Amy Paller discusses how advances in understanding type 2 inflammation are transforming pediatric atopic dermatitis care.
Dr Amy Paller discusses how advances in understanding type 2 inflammation are transforming pediatric atopic dermatitis care.
Dr Amy Paller discusses how...
08/01/2026
The Dermatologist
Raj Chovatiya
Videos
05/01/2026
Raj Chovatiya, MD, PhD; Riya Gandhi, MA
Dr Raj Chovatiya explores the neuroimmune mechanisms driving prurigo nodularis, highlighting the role of type 2 inflammation, IL-31–mediated itch signaling, and cytokines like IL-4 and IL-13 in fibrosis and neuronal sensitization.
Dr Raj Chovatiya explores the neuroimmune mechanisms driving prurigo nodularis, highlighting the role of type 2 inflammation, IL-31–mediated itch signaling, and cytokines like IL-4 and IL-13 in fibrosis and neuronal sensitization.
Dr Raj Chovatiya explores the...
05/01/2026
The Dermatologist
Amy paller
Videos
04/01/2026
Amy S. Paller, MD, MS; Riya Gandhi, MA
Dr Amy Paller discusses how recognizing pediatric atopic dermatitis as a type 2 inflammatory disease has transformed early treatment strategies, enabling safer and more proactive use of targeted therapies.
Dr Amy Paller discusses how recognizing pediatric atopic dermatitis as a type 2 inflammatory disease has transformed early treatment strategies, enabling safer and more proactive use of targeted therapies.
Dr Amy Paller discusses how...
04/01/2026
The Dermatologist
Peter Lio
Expert Insights
03/05/2026
Peter Lio, MD, FAAD; Riya Gandhi, MA
In this interview, Peter Lio, MD, explores how modern environmental exposures—from pollution to lifestyle shifts—are accelerating type 2 inflammation and fueling atopic dermatitis and seasonal allergies in today’s patients.
In this interview, Peter Lio, MD, explores how modern environmental exposures—from pollution to lifestyle shifts—are accelerating type 2 inflammation and fueling atopic dermatitis and seasonal allergies in today’s patients.
In this interview, Peter Lio,...
03/05/2026
Allergy & Immunology
Brian Kim, MD, MTR
Videos
03/02/2026
Brian Kim, MD, MTR, FAAD; Riya Gandhi, MA
Chronic itch in prurigo nodularis is increasingly understood as a neuroimmune process driven by type 2 cytokines rather than histamine alone. Dr Kim explores how IL-4, IL-13, and IL-31 interact with sensory neurons to sustain pruritus.
Chronic itch in prurigo nodularis is increasingly understood as a neuroimmune process driven by type 2 cytokines rather than histamine alone. Dr Kim explores how IL-4, IL-13, and IL-31 interact with sensory neurons to sustain pruritus.
Chronic itch in prurigo...
03/02/2026
The Dermatologist
Peter Lio
Clinical Insights
01/20/2026
Peter Lio, MD, FAAD; Riya Gandhi, MA
Dr Peter Lio discusses how urbanization, modern lifestyles, and shifting environmental exposures may be driving rising rates of allergic rhinitis, food allergy, and atopic dermatitis—and which exposures should most concern clinicians.
Dr Peter Lio discusses how urbanization, modern lifestyles, and shifting environmental exposures may be driving rising rates of allergic rhinitis, food allergy, and atopic dermatitis—and which exposures should most concern clinicians.
Dr Peter Lio discusses how...
01/20/2026
Allergy & Immunology
Cover Story
08/02/2025
Mona Shahriari, MD, FAAD
Join Dr Mona Shahriari for a high-level primer on how type 2 immune dysregulation drives this disease.
Join Dr Mona Shahriari for a high-level primer on how type 2 immune dysregulation drives this disease.
Join Dr Mona Shahriari for a...
08/02/2025
The Dermatologist
Asempa
Videos
08/06/2026
Oyetewa Boluwatito Asempa, MD, FAAD; Riya Gandhi, MA
Shared decision-making in alopecia areata is often more complex than it appears. Dr Oyetewa Asempa discusses aligning treatment goals, managing expectations, and improving patient-clinician communication.
Shared decision-making in alopecia areata is often more complex than it appears. Dr Oyetewa Asempa discusses aligning treatment goals, managing expectations, and improving patient-clinician communication.
Shared decision-making in...
08/06/2026
The Dermatologist
Draelos
Videos
08/06/2026
Zoe Diana Draelos, MD; Riya Gandhi, MA
Hair regrowth is only one measure of success in alopecia areata. Dr Zoe Draelos highlights patient-centered outcomes, quality of life, emotional well-being, and long-term disease control.
Hair regrowth is only one measure of success in alopecia areata. Dr Zoe Draelos highlights patient-centered outcomes, quality of life, emotional well-being, and long-term disease control.
Hair regrowth is only one...
08/06/2026
The Dermatologist
Draelos
Videos
08/06/2026
Zoe Diana Draelos, MD; Riya Gandhi, MA
Pediatric alopecia areata can have profound emotional and social consequences. Dr Zoe Draelos examines the unique psychological challenges facing children and adolescents with the disease.
Pediatric alopecia areata can have profound emotional and social consequences. Dr Zoe Draelos examines the unique psychological challenges facing children and adolescents with the disease.
Pediatric alopecia areata can...
08/06/2026
The Dermatologist
Draelos
Videos
08/06/2026
Zoe Diana Draelos, MD; Riya Gandhi, MA
Adapting to alopecia areata isn't always a linear process. Dr Zoe Draelos discusses the lasting emotional impact of the disease and why ongoing psychosocial support remains essential.
Adapting to alopecia areata isn't always a linear process. Dr Zoe Draelos discusses the lasting emotional impact of the disease and why ongoing psychosocial support remains essential.
Adapting to alopecia areata...
08/06/2026
The Dermatologist
Asempa
Videos
08/06/2026
Oyetewa Boluwatito Asempa, MD, FAAD; Riya Gandhi, MA
Treating alopecia areata extends beyond managing hair loss. Dr Oyetewa Asempa explores gaps in psychosocial care, patient communication, and integrating mental health into clinical practice.
Treating alopecia areata extends beyond managing hair loss. Dr Oyetewa Asempa explores gaps in psychosocial care, patient communication, and integrating mental health into clinical practice.
Treating alopecia areata extends...
08/06/2026
The Dermatologist
Guttman
Videos
08/06/2026
Emma Guttman-Yassky, MD, PhD; Riya Gandhi, MA
Successful alopecia areata treatment doesn't always mean therapy should end. Dr Emma Guttman discusses relapse risk, maintenance strategies, and setting realistic expectations for long-term disease management.
Successful alopecia areata treatment doesn't always mean therapy should end. Dr Emma Guttman discusses relapse risk, maintenance strategies, and setting realistic expectations for long-term disease management.
Successful alopecia areata...
08/06/2026
The Dermatologist
Emma Guttman
Videos
08/06/2026
Emma Guttman-Yassky, MD, PhD; Riya Gandhi, MA
Complete hair loss doesn't necessarily mean treatment failure in alopecia areata. Examine the latest evidence on therapeutic response, severe disease, and evolving treatment strategies.
Complete hair loss doesn't necessarily mean treatment failure in alopecia areata. Examine the latest evidence on therapeutic response, severe disease, and evolving treatment strategies.
Complete hair loss doesn't...
08/06/2026
The Dermatologist
Guttman
Videos
08/06/2026
Emma Guttman-Yassky, MD, PhD; Riya Gandhi, MA
Alopecia areata is more than hair loss. Dr Emma Guttman discusses the disease's psychosocial burden, autoimmune nature, and why viewing AA as purely cosmetic can undermine patient care.
Alopecia areata is more than hair loss. Dr Emma Guttman discusses the disease's psychosocial burden, autoimmune nature, and why viewing AA as purely cosmetic can undermine patient care.
Alopecia areata is more than...
08/06/2026
The Dermatologist
Craiglow
Videos
08/06/2026
Brittany Craiglow, MD; Riya Gandhi, MA
Despite major therapeutic advances, alopecia areata remains an area of unmet need. Dr Brittany Craiglow explores ongoing challenges in treatment access, research, and long-term disease management.
Despite major therapeutic advances, alopecia areata remains an area of unmet need. Dr Brittany Craiglow explores ongoing challenges in treatment access, research, and long-term disease management.
Despite major therapeutic...
08/06/2026
The Dermatologist
Craiglow
Videos
08/06/2026
Brittany Craiglow, MD; Riya Gandhi, MA
Growing awareness of alopecia areata has improved visibility, but stigma remains. Dr Brittany Craiglow discusses persistent misconceptions, social challenges, and opportunities for better patient support.
Growing awareness of alopecia areata has improved visibility, but stigma remains. Dr Brittany Craiglow discusses persistent misconceptions, social challenges, and opportunities for better patient support.
Growing awareness of alopecia...
08/06/2026
The Dermatologist

Quiz

Quiz
06/25/2026
Riya Gandhi, MA
Assess advanced concepts in type 2 inflammatory endotypes, shared therapeutic pathways, and practical treatment approaches in prurigo nodularis.
Assess advanced concepts in type 2 inflammatory endotypes, shared therapeutic pathways, and practical treatment approaches in prurigo nodularis.
Assess advanced concepts in type...
06/25/2026
The Dermatologist
itch
Quiz
06/15/2026
Riya Gandhi, MA
Test your clinical understanding of fibrotic remodeling and the mechanisms underlying persistent itch and chronic disease activity in prurigo nodularis.
Test your clinical understanding of fibrotic remodeling and the mechanisms underlying persistent itch and chronic disease activity in prurigo nodularis.
Test your clinical understanding...
06/15/2026
The Dermatologist
brain
Quiz
06/05/2026
Riya Gandhi, MA
Explore advanced concepts in neuroimmune communication, cytokine-driven itch amplification, and fibrotic signaling pathways involved in prurigo nodularis.
Explore advanced concepts in neuroimmune communication, cytokine-driven itch amplification, and fibrotic signaling pathways involved in prurigo nodularis.
Explore advanced concepts in...
06/05/2026
The Dermatologist
Quiz
04/15/2026
Riya Gandhi, MA
Test your expertise in identifying risk factors for persistent pediatric atopic dermatitis and understanding the interplay between barrier dysfunction and immune dysregulation.
Test your expertise in identifying risk factors for persistent pediatric atopic dermatitis and understanding the interplay between barrier dysfunction and immune dysregulation.
Test your expertise in...
04/15/2026
The Dermatologist
Quiz
04/05/2026
Riya Gandhi, MA
Assess advanced clinical reasoning in pediatric atopic dermatitis, including implications of type 2 inflammation for diagnosis, treatment timing, and systemic therapy decisions.
Assess advanced clinical reasoning in pediatric atopic dermatitis, including implications of type 2 inflammation for diagnosis, treatment timing, and systemic therapy decisions.
Assess advanced clinical...
04/05/2026
The Dermatologist
Quiz
03/15/2026
Riya Gandhi, MA
Challenge your understanding of direct and indirect cytokine–nerve interactions and mechanical hypersensitivity of type 2 signaling in prurigo nodularis.
Challenge your understanding of direct and indirect cytokine–nerve interactions and mechanical hypersensitivity of type 2 signaling in prurigo nodularis.
Challenge your understanding of...
03/15/2026
The Dermatologist
Quiz
03/10/2026
Riya Gandhi, MA
Explore the hierarchical and cooperative roles of IL-4, IL-13, and IL-31 in sustaining chronic itch and inflammation in prurigo nodularis.
Explore the hierarchical and cooperative roles of IL-4, IL-13, and IL-31 in sustaining chronic itch and inflammation in prurigo nodularis.
Explore the hierarchical and...
03/10/2026
The Dermatologist
Quiz
03/05/2026
Riya Gandhi, MA
Test your understanding of how type 2 immune signaling drives chronic itch in prurigo nodularis through complex neuroimmune interactions.
Test your understanding of how type 2 immune signaling drives chronic itch in prurigo nodularis through complex neuroimmune interactions.
Test your understanding of how...
03/05/2026
The Dermatologist
Quiz
02/26/2026
Riya Gandhi, MA
Explore the relationship between allergic disease trends, genetic timelines, and the clinical framework used to describe the progression of atopic conditions across childhood.
Explore the relationship between allergic disease trends, genetic timelines, and the clinical framework used to describe the progression of atopic conditions across childhood.
Explore the relationship between...
02/26/2026
The Dermatologist
Quiz
02/26/2026
Riya Gandhi, MA
Assess your understanding of early skin barrier interventions in infants and the clinical rationale for prompt treatment of atopic dermatitis in young children, including implications for long-term disease outcomes.
Assess your understanding of early skin barrier interventions in infants and the clinical rationale for prompt treatment of atopic dermatitis in young children, including implications for long-term disease outcomes.
Assess your understanding of...
02/26/2026
The Dermatologist
Quiz
06/25/2026
Riya Gandhi, MA
Assess advanced concepts in type 2 inflammatory endotypes, shared therapeutic pathways, and practical treatment approaches in prurigo nodularis.
Assess advanced concepts in type 2 inflammatory endotypes, shared therapeutic pathways, and practical treatment approaches in prurigo nodularis.
Assess advanced concepts in type...
06/25/2026
The Dermatologist
itch
Quiz
06/15/2026
Riya Gandhi, MA
Test your clinical understanding of fibrotic remodeling and the mechanisms underlying persistent itch and chronic disease activity in prurigo nodularis.
Test your clinical understanding of fibrotic remodeling and the mechanisms underlying persistent itch and chronic disease activity in prurigo nodularis.
Test your clinical understanding...
06/15/2026
The Dermatologist
brain
Quiz
06/05/2026
Riya Gandhi, MA
Explore advanced concepts in neuroimmune communication, cytokine-driven itch amplification, and fibrotic signaling pathways involved in prurigo nodularis.
Explore advanced concepts in neuroimmune communication, cytokine-driven itch amplification, and fibrotic signaling pathways involved in prurigo nodularis.
Explore advanced concepts in...
06/05/2026
The Dermatologist
Quiz
04/15/2026
Riya Gandhi, MA
Test your expertise in identifying risk factors for persistent pediatric atopic dermatitis and understanding the interplay between barrier dysfunction and immune dysregulation.
Test your expertise in identifying risk factors for persistent pediatric atopic dermatitis and understanding the interplay between barrier dysfunction and immune dysregulation.
Test your expertise in...
04/15/2026
The Dermatologist
Quiz
04/05/2026
Riya Gandhi, MA
Assess advanced clinical reasoning in pediatric atopic dermatitis, including implications of type 2 inflammation for diagnosis, treatment timing, and systemic therapy decisions.
Assess advanced clinical reasoning in pediatric atopic dermatitis, including implications of type 2 inflammation for diagnosis, treatment timing, and systemic therapy decisions.
Assess advanced clinical...
04/05/2026
The Dermatologist
Quiz
03/15/2026
Riya Gandhi, MA
Challenge your understanding of direct and indirect cytokine–nerve interactions and mechanical hypersensitivity of type 2 signaling in prurigo nodularis.
Challenge your understanding of direct and indirect cytokine–nerve interactions and mechanical hypersensitivity of type 2 signaling in prurigo nodularis.
Challenge your understanding of...
03/15/2026
The Dermatologist
Quiz
03/12/2026
Riya Gandhi, MA
How should clinicians redefine severe alopecia areata? When is it appropriate to treat ≤20% scalp involvement with oral JAK inhibitors? This expert-level quiz explores remission durability, treatment withdrawal, and practical strategies for...
How should clinicians redefine severe alopecia areata? When is it appropriate to treat ≤20% scalp involvement with oral JAK inhibitors? This expert-level quiz explores remission durability, treatment withdrawal, and practical strategies for...
How should clinicians redefine...
03/12/2026
The Dermatologist
Quiz
03/10/2026
Riya Gandhi, MA
Explore the hierarchical and cooperative roles of IL-4, IL-13, and IL-31 in sustaining chronic itch and inflammation in prurigo nodularis.
Explore the hierarchical and cooperative roles of IL-4, IL-13, and IL-31 in sustaining chronic itch and inflammation in prurigo nodularis.
Explore the hierarchical and...
03/10/2026
The Dermatologist
Quiz
03/05/2026
Riya Gandhi, MA
Test your understanding of how type 2 immune signaling drives chronic itch in prurigo nodularis through complex neuroimmune interactions.
Test your understanding of how type 2 immune signaling drives chronic itch in prurigo nodularis through complex neuroimmune interactions.
Test your understanding of how...
03/05/2026
The Dermatologist
psoriasis
Quiz
03/02/2026
Jessica Garlewicz
What is a key distinguishing feature of generalized pustular psoriasis that differentiates it from plaque psoriasis?
What is a key distinguishing feature of generalized pustular psoriasis that differentiates it from plaque psoriasis?
What is a key distinguishing...
03/02/2026
The Dermatologist