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Eosinophilic Disorders

Research Review
Pediatric Asthma Screening Identifies High Prevalence of Eosinophilic Esophagitis
07/22/2026
Rebecca Mashaw
The findings of a recent study support further evaluation of targeted screening strategies to promote earlier diagnosis and improve care for children at increased risk of EoE, such as those with asthma.
The findings of a recent study support further evaluation of targeted screening strategies to promote earlier diagnosis and improve care for children at increased risk of EoE, such as those with asthma.
The findings of a recent study...
07/22/2026
Allergy & Immunology
Research Review
Therapies Targeting Eosinophils Expand Options for Eosinophilic Gastrointestinal Disorders
07/22/2026
Rebecca Mashaw
A major review identifies important gaps for treatment of nonesophageal disease while substantial progress in targeted therapy for eosinophilic esophagitis.
A major review identifies important gaps for treatment of nonesophageal disease while substantial progress in targeted therapy for eosinophilic esophagitis.
A major review identifies...
07/22/2026
Allergy & Immunology
Conference Coverage
Kathryn Peterson, MD, on Diagnosing and Treating Eosinophilic Gastritis
03/25/2026
Kathryn Peterson, MD, MS
Dr Kathryn Peterson provides an overview of her presentation at the American Academy of Allergy, Asthma, and Immunology on eosinophilic gastric diseases other than EoE, including the challenges of diagnosis and options for treatment.
Dr Kathryn Peterson provides an overview of her presentation at the American Academy of Allergy, Asthma, and Immunology on eosinophilic gastric diseases other than EoE, including the challenges of diagnosis and options for treatment.
Dr Kathryn Peterson provides an...
03/25/2026
Allergy & Immunology
FDA Alert
FDA Approves Twice-Yearly Biologic for Severe Eosinophilic Asthma
02/18/2026
Jessica Garlewicz
Exdensur is the first ultra-long-acting biologic for this population, with a dosing schedule of just twice per year.
Exdensur is the first ultra-long-acting biologic for this population, with a dosing schedule of just twice per year.
Exdensur is the first...
02/18/2026
Allergy & Immunology
Joy Chang
Expert Insights
Joy Chang, MD, on Step Therapy for EoE: Part 2
02/05/2026
Joy Chang, MD
Dr Joy Chang continues her tutorial on therapy for eosinophilic esophagitis, including options for using dupilimab as step-down therapy for specific patients.
Dr Joy Chang continues her tutorial on therapy for eosinophilic esophagitis, including options for using dupilimab as step-down therapy for specific patients.
Dr Joy Chang continues her...
02/05/2026
Allergy & Immunology
Joy Chang
Conference Insights
Joy Chang, MD, on Step Therapy for EoE: Part 1
01/26/2026
Joy Chang, MD
In this video, Dr Joy Chang begins a two-part discussion on using step-up and step-down therapy in the treatment of eosinophilic esophagitis based on her presentation at the ACG scientific meeting.
In this video, Dr Joy Chang begins a two-part discussion on using step-up and step-down therapy in the treatment of eosinophilic esophagitis based on her presentation at the ACG scientific meeting.
In this video, Dr Joy Chang...
01/26/2026
Allergy & Immunology
Quiz
First-Line Treatment for EoE
12/31/2025
Rebecca Mashaw
What are the latest recommendations for first-line therapies for eosinophilic esophagitis? Take our quiz to test your knowledge!
What are the latest recommendations for first-line therapies for eosinophilic esophagitis? Take our quiz to test your knowledge!
What are the latest...
12/31/2025
Allergy & Immunology
Research Highlights
Dupilumab Shows Efficacy in Real-World Treatment of Eosinophilic Esophagitis
12/31/2025
Rebecca Mashaw
A meta-analysis pools data across multiple centers to show high rates of symptom resolution and histologic improvement among patients with EoE outside controlled trials.
A meta-analysis pools data across multiple centers to show high rates of symptom resolution and histologic improvement among patients with EoE outside controlled trials.
A meta-analysis pools data...
12/31/2025
Allergy & Immunology
Clinical Insights
EoE Review Emphasizes Early Diagnosis, Multimodal Monitoring
12/06/2025
Jessica Garlewicz
The increasing prevalence of EoE has positioned it as a major cause of dysphagia and food impaction, particularly in Western countries.
The increasing prevalence of EoE has positioned it as a major cause of dysphagia and food impaction, particularly in Western countries.
The increasing prevalence of EoE...
12/06/2025
Allergy & Immunology
Diagnostics
Component-Resolved Diagnostics Enhance Allergen Precision in EoE
12/06/2025
Jessica Garlewicz
The precision of CRD may allow clinicians to offer more tailored dietary guidance and reduce the burden of broad food elimination.
The precision of CRD may allow clinicians to offer more tailored dietary guidance and reduce the burden of broad food elimination.
The precision of CRD may allow...
12/06/2025
Allergy & Immunology
News
FDA Approves Budesonide Oral Suspension for EoE
02/28/2024
Rebecca Mashaw
The approval marks the first and only oral therapy for patients 11 and older with eosinophilic esophagitis.
The approval marks the first and only oral therapy for patients 11 and older with eosinophilic esophagitis.
The approval marks the first and...
02/28/2024
Gastroenterology
From Gastroenterology
Section Editor
Joy Weiling Chang, MD, MS
Joy Weiling Chang, MD
Assistant Professor of Medicine, Division of Gastroenterology
University of Michigan
Ann Arbor, Michigan

In the News

FDA Alert
FDA Approves Twice-Yearly Biologic for Severe Eosinophilic Asthma
02/18/2026
Jessica Garlewicz
Exdensur is the first ultra-long-acting biologic for this population, with a dosing schedule of just twice per year.
Exdensur is the first ultra-long-acting biologic for this population, with a dosing schedule of just twice per year.
Exdensur is the first...
02/18/2026
Allergy & Immunology
Research Highlights
BTK Inhibition With Rilzabrutinib Improves Symptoms in Uncontrolled Asthma
05/06/2026
Jessica Garlewicz
Researchers found Bruton's tyrosine kinase inhibition was associated with a numerical decrease in loss of asthma control and may represent “a novel mechanism to treat uncontrolled symptomatic asthma.”
Researchers found Bruton's tyrosine kinase inhibition was associated with a numerical decrease in loss of asthma control and may represent “a novel mechanism to treat uncontrolled symptomatic asthma.”
Researchers found Bruton's...
05/06/2026
Allergy & Immunology
Research Review
Remibrutinib Shows Promise in IgE-Mediated Peanut Allergy
04/23/2026
Riya Gandhi, MA
These findings support continued development of remibrutinib as a potential oral therapeutic option for food allergy.
These findings support continued development of remibrutinib as a potential oral therapeutic option for food allergy.
These findings support continued...
04/23/2026
Allergy & Immunology
Research Review
Higher Phytochemical Intake Linked to Improved Pediatric Asthma Outcomes
03/18/2026
Rebecca Mashaw
Among the 150 children with asthma, those with higher Dietary Phytochemical Index intake had significantly better clinical scores and lower levels of inflammation than those in the lowest tertile.
Among the 150 children with asthma, those with higher Dietary Phytochemical Index intake had significantly better clinical scores and lower levels of inflammation than those in the lowest tertile.
Among the 150 children with...
03/18/2026
Allergy & Immunology
Research Summary
Acute Urticaria Incidence Declined During COVID-19
03/18/2026
Jessica Garlewicz
The findings of an analysis underscore the potential role of common viral infections as a trigger for AU and offer insight into changing disease patterns during the COVID-19 pandemic.
The findings of an analysis underscore the potential role of common viral infections as a trigger for AU and offer insight into changing disease patterns during the COVID-19 pandemic.
The findings of an analysis...
03/18/2026
Allergy & Immunology
Emerging Therapies
Advances in HAE Therapeutics Highlight Path Toward Personalized, Patient-Centered Care
03/02/2026
Jessica Garlewicz
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management...
03/02/2026
Allergy & Immunology
FDA Alert
FDA Approves Twice-Yearly Biologic for Severe Eosinophilic Asthma
02/18/2026
Jessica Garlewicz
Exdensur is the first ultra-long-acting biologic for this population, with a dosing schedule of just twice per year.
Exdensur is the first ultra-long-acting biologic for this population, with a dosing schedule of just twice per year.
Exdensur is the first...
02/18/2026
Allergy & Immunology
Research Review
MDD in Asthma Patients Associated With Worse Outcomes in Older Adults
01/29/2026
Rebecca Mashaw
A recent cohort study by highlights how psychological health influences asthma control and healthcare utilization, underscoring a need for integrated care in older populations.
A recent cohort study by highlights how psychological health influences asthma control and healthcare utilization, underscoring a need for integrated care in older populations.
A recent cohort study by...
01/29/2026
Allergy & Immunology
Research Summary
Barriers to Normalization Persist for U.S. Patients With Hereditary Angioedema
01/18/2026
Rebecca Mashaw
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight...
01/18/2026
Allergy & Immunology
Comorbidities
Oscillometry-Based Markers Reveal Airway Dynamics in Asthma–OSA Overlap
12/06/2025
Jessica Garlewicz
While the exact mechanistic interactions remain complex, oscillometric patterns provided insight into changes in respiratory rhythm and resistance related to nocturnal airway collapse and remodeling.
While the exact mechanistic interactions remain complex, oscillometric patterns provided insight into changes in respiratory rhythm and resistance related to nocturnal airway collapse and remodeling.
While the exact mechanistic...
12/06/2025
Allergy & Immunology
Morbidity & Mortality
Mortality From Coexisting Asthma and Cardiovascular Disease Rising
12/06/2025
Jessica Garlewicz
This analysis found significant disparities in mortality across demographic groups.
This analysis found significant disparities in mortality across demographic groups.
This analysis found significant...
12/06/2025
Allergy & Immunology

Popular Articles

Sacha Gnjatic headshot on white background
Clinical Insights
Unraveling Immune Biomarkers in Endometrial Cancer Therapy
05/07/2025
Sacha Gnjatic, PhD
A guest expert discusses groundbreaking research from a national immunotherapy network aimed at identifying biomarkers that predict response to cancer treatments, with a focus on endometrial cancer and novel drug combinations.
A guest expert discusses groundbreaking research from a national immunotherapy network aimed at identifying biomarkers that predict response to cancer treatments, with a focus on endometrial cancer and novel drug combinations.
A guest expert discusses...
05/07/2025
Journal of Clinical Pathways
Peter Lio
Clinical Insights
Urbanization, Lifestyle, and Skin Barrier Damage in Atopic Dermatitis
01/20/2026
Peter Lio, MD, FAAD; Riya Gandhi, MA
Dr Peter Lio discusses how urbanization, modern lifestyles, and shifting environmental exposures may be driving rising rates of allergic rhinitis, food allergy, and atopic dermatitis—and which exposures should most concern clinicians.
Dr Peter Lio discusses how urbanization, modern lifestyles, and shifting environmental exposures may be driving rising rates of allergic rhinitis, food allergy, and atopic dermatitis—and which exposures should most concern clinicians.
Dr Peter Lio discusses how...
01/20/2026
Allergy & Immunology
Research Review
Injectable On-Demand HAE Treatments Undermine Quality of Life, Study Finds
03/18/2026
Rebecca Mashaw
All participants reported at least one negative impact on HRQoL due to injectable on-demand treatment.
All participants reported at least one negative impact on HRQoL due to injectable on-demand treatment.
All participants reported at...
03/18/2026
Allergy & Immunology
Research Review
Drug-Related Anaphylaxis Mortality Remains Stable but Disparities Persist
11/13/2025
Jessica Garlewicz
A new national analysis of death certificate data from 2011 to 2023 reveals that drug-related anaphylaxis continues to be a significant contributor to anaphylaxis-related deaths in the United States, particularly among older adults and...
A new national analysis of death certificate data from 2011 to 2023 reveals that drug-related anaphylaxis continues to be a significant contributor to anaphylaxis-related deaths in the United States, particularly among older adults and...
A new national analysis of death...
11/13/2025
Allergy & Immunology
Jonathan Bernstein, MD
Clinical Insights
Jonathan Bernstein, MD, on Chronic Spontaneous Urticaria
01/20/2026
Jonathan A. Bernstein, MD
Allergist Jonathan Bernstein, MD, provided an in-depth review of diagnosing and treating chronic spontaneous urticaria.
Allergist Jonathan Bernstein, MD, provided an in-depth review of diagnosing and treating chronic spontaneous urticaria.
Allergist Jonathan Bernstein,...
01/20/2026
Allergy & Immunology

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