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Type 2 Inflammation Topic Center

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Utilization and Spending Changes With Preventive Drug Lists
12/12/2023
True or False: A case-control study found that exempting asthma medications from the deductible through preventive drug lists was associated with a modest absolute increase in adherence to controller medications and significantly reduced...
True or False: A case-control study found that exempting asthma medications from the deductible through preventive drug lists was associated with a modest absolute increase in adherence to controller medications and significantly reduced...
True or False: A case-control...
12/12/2023
First Report Managed Care
News
Utilization Increases and Spending Decreases With Preventive Drug Lists for Asthma Medications
11/29/2023
Lisa Kuhns, PhD, MD
Reducing cost-sharing for asthma medications through a preventive drug list (PDL) increases adherence to controller medications, according to a study published in JAMA Network Open.
Reducing cost-sharing for asthma medications through a preventive drug list (PDL) increases adherence to controller medications, according to a study published in JAMA Network Open.
Reducing cost-sharing for asthma...
11/29/2023
First Report Managed Care
News
Asthma Management Critical During Pregnancy
11/21/2023
Jolynn Tumolo
Potential roadblocks to adequate management of asthma in pregnant women include nonadherence to medication, lack of education, and smoking habits. The review mentions a retrospective study that found pregnant women with asthma tended to...
Potential roadblocks to adequate management of asthma in pregnant women include nonadherence to medication, lack of education, and smoking habits. The review mentions a retrospective study that found pregnant women with asthma tended to...
Potential roadblocks to adequate...
11/21/2023
First Report Managed Care
News
The Role of Fungi in Allergic Disease and the Evolutionary Advantage of Type 2 Immune Response
11/07/2023
Hannah Musick
This article highlights the global rise in allergic diseases and the significant economic burden they pose, focusing on the role of fungi in triggering allergic reactions and the need for further research to understand why type 2 immune...
This article highlights the global rise in allergic diseases and the significant economic burden they pose, focusing on the role of fungi in triggering allergic reactions and the need for further research to understand why type 2 immune...
This article highlights the...
11/07/2023
First Report Managed Care
News
Biologics for Asthma: Targeting Type 2 Inflammation in Severe Cases
10/13/2023
Danielle Sposato
Currently, most biologics used to treat asthma are approved for individuals with uncontrolled moderate-to-severe asthma and elevated biomarkers of type 2 (T2) inflammation, driven by T2 cytokines like IL-4, IL-13, and IL-5, according to a...
Currently, most biologics used to treat asthma are approved for individuals with uncontrolled moderate-to-severe asthma and elevated biomarkers of type 2 (T2) inflammation, driven by T2 cytokines like IL-4, IL-13, and IL-5, according to a...
Currently, most biologics used...
10/13/2023
First Report Managed Care
News
Satellite Data Reveals a Link Between NO2 Exposure and Asthma Exacerbations
10/02/2023
Lisa Kuhns, PhD, MD
Incorporating ground-level satellite-derived estimates of NO2 into multivariable models reveals a relationship between NO2 exposure and asthma exacerbations, according to a study published in AMIA Joint Summits on Translational Science.
Incorporating ground-level satellite-derived estimates of NO2 into multivariable models reveals a relationship between NO2 exposure and asthma exacerbations, according to a study published in AMIA Joint Summits on Translational Science.
Incorporating ground-level...
10/02/2023
First Report Managed Care
News
Using Socioeconomic, Insurance Status to Help Identify Risk Factors for Uncontrolled Asthma in a US Cohort
09/20/2023
Julie Gould
"Socioeconomic and insurance status, asthma severity, and prior health care utilization have been shown to predict the risk of hospitalization, in the US," explained authors. "Thus, identifying patients who are at the higher risk for...
"Socioeconomic and insurance status, asthma severity, and prior health care utilization have been shown to predict the risk of hospitalization, in the US," explained authors. "Thus, identifying patients who are at the higher risk for...
"Socioeconomic and insurance...
09/20/2023
First Report Managed Care
News
Modulating ILC2s in Allergic Airway Inflammation for Therapeutic Intervention
09/18/2023
Danielle Sposato
In a study addressing limitations in previous research, scientists investigate the role of acetylcholine (ACh) in allergic airway inflammation, emphasizing the challenges in distinguishing direct effects on group 2 innate lymphoid cells...
In a study addressing limitations in previous research, scientists investigate the role of acetylcholine (ACh) in allergic airway inflammation, emphasizing the challenges in distinguishing direct effects on group 2 innate lymphoid cells...
In a study addressing...
09/18/2023
First Report Managed Care
News
Ongoing Study of IL-23 in Asthma May Yield More Treatment Options
09/11/2023
Jolynn Tumolo
A new study suggests that gaining a better understanding of the relationship between interleukin (IL)-23 and airway inflammation in asthma patients could lead to alternative treatment options beyond traditional anti-type 2 inflammatory...
A new study suggests that gaining a better understanding of the relationship between interleukin (IL)-23 and airway inflammation in asthma patients could lead to alternative treatment options beyond traditional anti-type 2 inflammatory...
A new study suggests that...
09/11/2023
First Report Managed Care
News
New Platform Leverages Real-World Evidence for Type 2 Inflammation Immunological Disease Research
08/07/2023
Hannah Musick
Researchers introduce Immunolab, a platform that generates real-world evidence to provide insights and conduct research on immunological diseases related to type 2 inflammation.
Researchers introduce Immunolab, a platform that generates real-world evidence to provide insights and conduct research on immunological diseases related to type 2 inflammation.
Researchers introduce Immunolab,...
08/07/2023
First Report Managed Care
News
Therapy Benefits People With Type 2 Asthma Regardless of Inhaled Corticosteroid Dose
08/01/2023
Jolynn Tumolo
New findings indicate a biologic therapy was efficacious for up to 3 years in patients with uncontrolled, moderate-to-severe asthma.
New findings indicate a biologic therapy was efficacious for up to 3 years in patients with uncontrolled, moderate-to-severe asthma.
New findings indicate a biologic...
08/01/2023
First Report Managed Care

Newsfeed

News
Utilization Increases and Spending Decreases With Preventive Drug Lists for Asthma Medications
11/29/2023
Lisa Kuhns, PhD, MD
Reducing cost-sharing for asthma medications through a preventive drug list (PDL) increases adherence to controller medications, according to a study published in JAMA Network Open.
Reducing cost-sharing for asthma medications through a preventive drug list (PDL) increases adherence to controller medications, according to a study published in JAMA Network Open.
Reducing cost-sharing for asthma...
11/29/2023
First Report Managed Care
News
Asthma Management Critical During Pregnancy
11/21/2023
Jolynn Tumolo
Potential roadblocks to adequate management of asthma in pregnant women include nonadherence to medication, lack of education, and smoking habits. The review mentions a retrospective study that found pregnant women with asthma tended to...
Potential roadblocks to adequate management of asthma in pregnant women include nonadherence to medication, lack of education, and smoking habits. The review mentions a retrospective study that found pregnant women with asthma tended to...
Potential roadblocks to adequate...
11/21/2023
First Report Managed Care
News
The Role of Fungi in Allergic Disease and the Evolutionary Advantage of Type 2 Immune Response
11/07/2023
Hannah Musick
This article highlights the global rise in allergic diseases and the significant economic burden they pose, focusing on the role of fungi in triggering allergic reactions and the need for further research to understand why type 2 immune...
This article highlights the global rise in allergic diseases and the significant economic burden they pose, focusing on the role of fungi in triggering allergic reactions and the need for further research to understand why type 2 immune...
This article highlights the...
11/07/2023
First Report Managed Care
News
Biologics for Asthma: Targeting Type 2 Inflammation in Severe Cases
10/13/2023
Danielle Sposato
Currently, most biologics used to treat asthma are approved for individuals with uncontrolled moderate-to-severe asthma and elevated biomarkers of type 2 (T2) inflammation, driven by T2 cytokines like IL-4, IL-13, and IL-5, according to a...
Currently, most biologics used to treat asthma are approved for individuals with uncontrolled moderate-to-severe asthma and elevated biomarkers of type 2 (T2) inflammation, driven by T2 cytokines like IL-4, IL-13, and IL-5, according to a...
Currently, most biologics used...
10/13/2023
First Report Managed Care
News
Satellite Data Reveals a Link Between NO2 Exposure and Asthma Exacerbations
10/02/2023
Lisa Kuhns, PhD, MD
Incorporating ground-level satellite-derived estimates of NO2 into multivariable models reveals a relationship between NO2 exposure and asthma exacerbations, according to a study published in AMIA Joint Summits on Translational Science.
Incorporating ground-level satellite-derived estimates of NO2 into multivariable models reveals a relationship between NO2 exposure and asthma exacerbations, according to a study published in AMIA Joint Summits on Translational Science.
Incorporating ground-level...
10/02/2023
First Report Managed Care
News
Using Socioeconomic, Insurance Status to Help Identify Risk Factors for Uncontrolled Asthma in a US Cohort
09/20/2023
Julie Gould
"Socioeconomic and insurance status, asthma severity, and prior health care utilization have been shown to predict the risk of hospitalization, in the US," explained authors. "Thus, identifying patients who are at the higher risk for...
"Socioeconomic and insurance status, asthma severity, and prior health care utilization have been shown to predict the risk of hospitalization, in the US," explained authors. "Thus, identifying patients who are at the higher risk for...
"Socioeconomic and insurance...
09/20/2023
First Report Managed Care
News
Modulating ILC2s in Allergic Airway Inflammation for Therapeutic Intervention
09/18/2023
Danielle Sposato
In a study addressing limitations in previous research, scientists investigate the role of acetylcholine (ACh) in allergic airway inflammation, emphasizing the challenges in distinguishing direct effects on group 2 innate lymphoid cells...
In a study addressing limitations in previous research, scientists investigate the role of acetylcholine (ACh) in allergic airway inflammation, emphasizing the challenges in distinguishing direct effects on group 2 innate lymphoid cells...
In a study addressing...
09/18/2023
First Report Managed Care
News
Ongoing Study of IL-23 in Asthma May Yield More Treatment Options
09/11/2023
Jolynn Tumolo
A new study suggests that gaining a better understanding of the relationship between interleukin (IL)-23 and airway inflammation in asthma patients could lead to alternative treatment options beyond traditional anti-type 2 inflammatory...
A new study suggests that gaining a better understanding of the relationship between interleukin (IL)-23 and airway inflammation in asthma patients could lead to alternative treatment options beyond traditional anti-type 2 inflammatory...
A new study suggests that...
09/11/2023
First Report Managed Care
News
New Platform Leverages Real-World Evidence for Type 2 Inflammation Immunological Disease Research
08/07/2023
Hannah Musick
Researchers introduce Immunolab, a platform that generates real-world evidence to provide insights and conduct research on immunological diseases related to type 2 inflammation.
Researchers introduce Immunolab, a platform that generates real-world evidence to provide insights and conduct research on immunological diseases related to type 2 inflammation.
Researchers introduce Immunolab,...
08/07/2023
First Report Managed Care
News
Therapy Benefits People With Type 2 Asthma Regardless of Inhaled Corticosteroid Dose
08/01/2023
Jolynn Tumolo
New findings indicate a biologic therapy was efficacious for up to 3 years in patients with uncontrolled, moderate-to-severe asthma.
New findings indicate a biologic therapy was efficacious for up to 3 years in patients with uncontrolled, moderate-to-severe asthma.
New findings indicate a biologic...
08/01/2023
First Report Managed Care
News
FDA Issues Final Guidance on Biosimilar Prior Approval Supplements
09/10/2025
Grace Taylor, MS, MA
The US Food and Drug Administration (FDA) has finalized guidance clarifying 6 categories of biosimilar prior approval supplements, setting review goals that could shape timelines for new indications and payer coverage decisions.
The US Food and Drug Administration (FDA) has finalized guidance clarifying 6 categories of biosimilar prior approval supplements, setting review goals that could shape timelines for new indications and payer coverage decisions.
The US Food and Drug...
09/10/2025
First Report Managed Care
News
High Health Care Burden Among People with Hemophilia A Experiencing Bleeding or Joint Complications
09/10/2025
Juliet Gallagher
New real-world evidence shows that people with hemophilia A who experience bleeding or joint complications face significantly higher health care utilization and comorbidity burden.
New real-world evidence shows that people with hemophilia A who experience bleeding or joint complications face significantly higher health care utilization and comorbidity burden.
New real-world evidence shows...
09/10/2025
First Report Managed Care
News
Confronting the HIV Epidemic: Addressing Gaps in Access, Adherence, and Equity
09/02/2025
Juliet Gallagher
At a recent AMCP conference, health care leaders Maria Lopes, MD, and Steve Cohen, MD, highlighted the persistent and unique challenges of HIV management in the US, emphasizing that despite medical advancements, HIV remains classified as an...
At a recent AMCP conference, health care leaders Maria Lopes, MD, and Steve Cohen, MD, highlighted the persistent and unique challenges of HIV management in the US, emphasizing that despite medical advancements, HIV remains classified as an...
At a recent AMCP conference,...
09/02/2025
First Report Managed Care
News
Industry Payments and Their Role in MS Drug Selection Among High-Volume Prescribers
08/28/2025
Juliet Gallagher
A recent observational study explored the prevalence of industry payments to neurologists who prescribe multiple sclerosis (MS) disease-modifying therapies (DMTs), uncovering significant associations between such payments and prescribing...
A recent observational study explored the prevalence of industry payments to neurologists who prescribe multiple sclerosis (MS) disease-modifying therapies (DMTs), uncovering significant associations between such payments and prescribing...
A recent observational study...
08/28/2025
First Report Managed Care
News
Medicare Advantage Plans See Double-Digit Satisfaction Drop as Medical Costs Soar
08/22/2025
Juliet Gallagher
Member satisfaction with Medicare Advantage (MA) plans has seen a significant decline, according to J.D. Power’s 2025 report, reflecting a broader set of financial and policy pressures now facing the MA landscape.
Member satisfaction with Medicare Advantage (MA) plans has seen a significant decline, according to J.D. Power’s 2025 report, reflecting a broader set of financial and policy pressures now facing the MA landscape.
Member satisfaction with...
08/22/2025
First Report Managed Care
News
Expanding Assertive Community Treatment to Transform Care for Complex Patients
08/20/2025
Lisa Kuhns, PhD, MD
A new study shows that health systems can rely on assertive community treatment (ACT), which has strong evidence supporting its effectiveness for treating the most complex, least engaged patients.
A new study shows that health systems can rely on assertive community treatment (ACT), which has strong evidence supporting its effectiveness for treating the most complex, least engaged patients.
A new study shows that health...
08/20/2025
First Report Managed Care
News
AAM White Paper Spotlights Legislative Path to Breaking Biosimilar Patent Barriers
08/18/2025
Grace Taylor, MS, MA
A recent white paper from the Association for Accessible Medicines exposes how brand-name drug patent tactics block biosimilar access and urges Congress to act on 3 key reforms to lower drug costs.
A recent white paper from the Association for Accessible Medicines exposes how brand-name drug patent tactics block biosimilar access and urges Congress to act on 3 key reforms to lower drug costs.
A recent white paper from the...
08/18/2025
First Report Managed Care
News
FDA Expands Approval of Alhemo for Hemophilia A and B Without Inhibitors
08/14/2025
Juliet Gallagher
Novo Nordisk has announced the US Food and Drug Administration (FDA) approval of Alhemo (concizumab-mtci) for use as a once-daily subcutaneous prophylactic treatment in people 12 years and older with hemophilia A or B (HA/HB) without...
Novo Nordisk has announced the US Food and Drug Administration (FDA) approval of Alhemo (concizumab-mtci) for use as a once-daily subcutaneous prophylactic treatment in people 12 years and older with hemophilia A or B (HA/HB) without...
Novo Nordisk has announced the...
08/14/2025
First Report Managed Care
News
High-Efficacy Multiple Sclerosis Therapies Linked to Fewer Emergency Department Visits and Lower Risk
08/13/2025
Lisa Kuhns, PhD, MD
High-efficacy disease-modifying therapies (DMTs) for multiple sclerosis (MS) are linked to a reduced likelihood of emergency department (ED) visits, according to a study published in Neurology.
High-efficacy disease-modifying therapies (DMTs) for multiple sclerosis (MS) are linked to a reduced likelihood of emergency department (ED) visits, according to a study published in Neurology.
High-efficacy disease-modifying...
08/13/2025
First Report Managed Care
News
Roctavian Demonstrates Sustained Efficacy and Safety in Patients With Hemophilia A
08/04/2025
Grace Taylor, MS, MA
Five-year data from BioMarin’s phase 3 trial reveals Roctavian’s long-term efficacy, safety, and quality-of-life benefits for adults with severe hemophilia A.
Five-year data from BioMarin’s phase 3 trial reveals Roctavian’s long-term efficacy, safety, and quality-of-life benefits for adults with severe hemophilia A.
Five-year data from BioMarin’s...
08/04/2025
First Report Managed Care
FRMC Volume 22, Issue 3

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September 2025
Volume 22
Issue 3
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