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Controlled Antegrade and Retrograde Tracking (CART) Technique Via Epicardial Collaterals: Feasible and Safe

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J INVASIVE CARDIOL 2026. doi:10.25270/jic/26.00039. Epub April 21, 2026.

A 59-year-old man with exertional angina and coronary angiography showing chronic total occlusion (CTO) of the right coronary artery (RCA) with collateral filling from the left anterior descending artery (LAD) (Figure 1). Dual injection revealed an ambiguous proximal cap, a very long occlusion, and the distal cap at the bifurcation (Video 1).

 

Figure 1.segment_occlusion
Figure 1. (A) Long segment of the occlusion: arrows indicate the proximal and distal caps. (B) Alternative angiographic view.

 

A primary retrograde strategy was selected but septal collateral wiring was unsuccessful. Epicardial collaterals from the LAD were subsequently crossed (Figure 2, Video 2); however, a retrograde wire (Confianza Pro 12; ASAHI INTECC) failed to puncture the distal cap. Antegrade wire (Gladius MG; ASAHI INTEC) knuckle was used until just before it reached the distal cap (Figure 3, Videos 3 and 4). A 3.0 x 20-mm TREK balloon (Abbott) was delivered retrogradely through the epicardial collateral and inflated at the bifurcation (Video 5). Next, an antegrade wire (Gladius EX; ASAHI INTECC) was delivered into the distal true lumen of the posterior descending artery (Figure 4, Video 6). The RCA was successfully stented with an XIENCE Pro drug-eluting stent (Abbott), with restoration of Thrombolysis in Myocardial Infarction 3 flow (Figure 5, Video 7).

 

Figure 2.unsuccesful_septal_wiring
Figure 2. (A) Unsuccessful septal wiring. (B) Successful crossing of epicardial collateral from the atrioventricular circumflex artery. The wire landed at the distal cap, which was difficult to puncture with heavy tip load wires and had to be abandoned.

 

Figure 3. (A) The antegrade knuckled Fielder XT guidewire
Figure 3. (A) The antegrade knuckled Fielder XT guidewire (ASAHI INTECC). (B) Successful crossing of the epicardial collateral from the left anterior descending artery.

 

Figure 4. Controlled Antegrade and Retrograde Tracking (CART) technique
Figure 4. (A) Both antegrade and retrograde wires were positioned and ready for the Controlled Antegrade and Retrograde Tracking (CART) technique. (B) The retrograde wire was positioned in the right posterolateral ventricular branch, and the balloon advanced over it to facilitate CART (arrow).

 

Figure 5. An antegrade wire was delivered into the distal true lumen
Figure 5. (A) An antegrade wire was delivered into the distal true lumen of the posterior descending artery, and balloon angioplasty was subsequently performed. (B) The final angiographic result after drug-eluting stents were placed in the right coronary artery.

 

Epicardial collateral manipulation carries a recognized risk of perforation and tamponade. In this case, the Controlled Antegrade and Retrograde Tracking (CART) technique via epicardial channel served as a definitive bailout strategy after failure of septal retrograde and reverse CART techniques, enabling successful recanalization. This case shows that, through suitable epicardial collaterals, CART is feasible and can be used for a successful CTO-PCI outcome.

 

Affiliations and Disclosures

Tarek Abdeldayem, MD1; Mustafa Tigen, MD;2 Omer Gogtekin, MD3; Mohaned Egred, BSc (Hons), MB, ChB, MD, FRCP, FESC1,4

From the 1Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2Marmara University, School of Medicine, Department of Cardiology, Istanbul, Turkey; 3Memorial Hospital, Istanbul, Turkey; 4School of Medicine, University of Sunderland, Sunderland.

Disclosures: The authors report no financial relationships or conflicts of interest regarding the content herein.

Consent statement: Consent was obtained from the patient for the procedure and all that followed.

Address for correspondence: Mohaned Egred, BSc (Hons), MB, ChB, MD, FRCP, FESC, Freeman Hospital, Newcastle upon Tyne NE7 7DN, United Kingdom. Email: m.egred@nhs.net; X: @mohanedegred