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Deep Vein Arterialization

Wound Care After Deep Vein Arterialization: The DPM’s Role

November 2026

Robert M. Sage, DPM, after his recent ASPS session, discusses the podiatrist’s role in wound management after deep vein arterialization (DVA), from infection control and offloading to monitoring circuit patency. He shares his perspective on surgical timing, coordination with vascular specialists, and preparing patients for a prolonged limb salvage process. 

Key Takeaways 

  • Dr. Sage emphasizes infection source control, wound stabilization, and offloading while the DVA circuit matures, with careful consideration of wound closure and subsequent surgical timing. 

  • Follow-up requires surveillance of circuit patency and wound progression; loss of previously detectable arterialized flow warrants prompt communication with the vascular team. 

  • Close collaboration among podiatric and vascular clinicians, consistent sharing of wound assessments, and patient education about the months-long healing process are central priorities in Dr. Sage’s approach. 


After deep vein arterialization (DVA), what do you feel are the DPM’s most important priorities, and how should wound management—including debridement and offloading—differ, if at all, from care following conventional arterial revascularization? 

Much like as we have been trained in infection management in these situations, source control is essential. Abscesses, wet gangrene, gas, and acute osteomyelitis need debridement and removal.  It is okay to leave and monitor dry gangrene. We may need to plan repeat debridements, prior to DVA intervention, and we may need to do more debridements if we are forced to because of recurring infection, after DVA, but before our definitive surgery, to properly achieve source control. 

We do not want to close the skin on these patients prior to DVA intervention, and we do not want to close the skin at definitive amputation. In my experience, this will create too much tension on the wound and will lead to failure. It is okay to close the fascial layer, however a guillotine amputation is essential in these cases. We need create and maintain a stable wound until the circuit matures.1,2  

While we are awaiting maturation of the circuit, I prefer povidone-iodine wet-to-dry dressings to keep the wound stable and prevent infection. While we are in this stage, we are not looking to use advanced tissue products and we are trying to keep the wound relatively dry. 

Offloading is critical; I feel this is even more important than after traditional revascularization, with non-weight-bearing, via a wheelchair, knee rolling walker, or similar apparatus to prevent pressure on the wound. Heel protection is important as well, but we as podiatrists, are very good at providing heel protection for those who are not as mobile and at risk for further breakdown. 

After circuit maturation, during definitive surgery, I find that it will bleed profusely.  The use of tourniquets, during definitive surgery and significant compression on these wounds after definitive surgery increases the likelihood that the newly developing circuit will thrombose and greatly threatens our chance of limb salvage.   

I typically look to achieve hemostasis through cautery, and topical hemostatic agents available in our operating room. 

Negative pressure wound therapy (NPWT) and cellular and tissue-based products are possibilities after definitive amputation, but we drop NPWT pressure to 75 mmHg for these patients. 

During follow-up, how do you distinguish an expected healing course from changes that warrant prompt vascular reassessment? What findings should podiatrists and other wound care clinicians be especially alert to? 

Edema is expected. We are taking an area that has not been getting proper circulation and sending lots of blood to the area.  Allowing the patient to hang the legs down is advised to allow for natural hydrostatic pressure and to encourage further formation of venous collaterals. 

New necrosis is expected. It may be superficial or deeper.  We are not to panic when this is seen.  We need to allow this to demarcate prior to further intervention. This might be due to steal from existing collaterals and not failure of the procedure. 

Pain is expected and it may be severe. It could be inflammatory pain, wound pain, reperfusion pain, neuropathic pain, or a combination of the above. Collaboration with the team on appropriate pain control is paramount. 

Patency should be assessed frequently as most of the stenosis or occlusions are found while awaiting circuit maturation. This can be assessed by a hand-held Doppler in the podiatrist's office but also could be done by a vascular lab with duplex TcPO2 or digital subtraction angiography.  

Vascular specialists will continue to follow and typically perform duplex ultrasound  typically done at 1 week, 4 weeks, 3 months, 6 months and 1 year at the inflow artery, proximal 1/3 of the stented artery, the midsegment of the stented vein, the distal 1/3 of the segment and the outflow vein.  The AV circuit can be considered patent if pulsating flow can be heard plantar to the calcaneus. Duplex TcPO2 is important because duplex examinations may miss stealing side branches which may hinder our healing of the wounds. This may be done in our offices or by our vascular colleagues. 

Findings that we need to be alerted to are the inability to hear arterialized flow in the subcutaneous spaces on the plantar heel, along with losing the ability to hear the flow on the handheld Doppler, that was present before. 

How should the DPM and vascular team coordinate decisions about the timing of further foot surgery, such as debridement or minor amputation, and what should patients and caregivers understand about the path toward healing and a functional limb? 

In the best situations, the DPM and the vascular team should see these patients together. The DPM typically sees the patient at least weekly, and the vascular team at least monthly until the wound is healed. 

If this is not possible, in my experience, the DPM should insert pictures along with the description of the wound and the progression or regression of the wounds in the chart and the notes from every visit should be sent to all treating providers, regardless of whether all providers are in the same system. The same should apply to the vascular specialist after they see the patient. 

All parties need to have each other's cell phone numbers and not be afraid to call to discuss any finding that is not expected. Conversely, all should be willing to take the phone call and work a patient in to the schedule to do whatever is possible to save the patient's limb and life. 

Patients and caregivers need to understand that this is a several month- long process to work towards healing this wound, and that there is a significant difference between the structure of the arteries and the veins that make the newly arterialized veins especially vulnerable to pressure and to thrombosis.  

They also need to understand that it may look like we are waiting "forever" prior to doing the definitive surgery. They have to understand that this is a last-ditch (otherwise “no-option”) effort at limb salvage to prevent amputation and we are trying to make veins act like arteries. This takes a while and is very fragile. 

What do you feel are the biggest misconceptions that clinicians have about DVA, and the subsequent treatment course? 

I feel that many clinicians do not understand the timeline that is involved with this procedure and the crucial nature of protecting the pedal venous arch to maintain the circulation to the foot. I also feel that most of us try to close wounds that have the ability to close, but that even a "no tension" closure is too much tension on the wound in patients post-DVA. I also believe that we know, but may not truly appreciate, the tremendous importance of not applying any compression on these wounds so as not to thrombose the vessels. These misconceptions are addressable, however, and with clear communication and careful consideration, lower extremity professionals can be vital contributors to improving outcomes for these patients.   

Dr. Sage is a Trustee of the American Podiatric Medical Association and practices in Beloit, WI. 

References  

  1. Huizing E, Schreve MA, Kum S, de Borst GJ, de Vries J-PPM, Ünlü Ç. Postprocedural Management in Patients After Percutaneous Deep Venous Arterialization: An Expert Opinion. J Endovasc Ther. 2024;31(6):1052-1064  

  1. Dua A, Rose-Sauld S, Ferraro L, Sweeney E. The Massachusetts General Hospital Approach to Transcatheter Arterialization of the Deep Veins for Advanced Limb Salvage: Protocols and Procedures. Springer, 2023.

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