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MASLD in 2050

Rebecca Mashaw
07/18/2025

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Manal Abdelmalek
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How I Treat MASLD/MASH: Manal Abdelmalek, MD
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Dr Abdelmalek reviews her approach to screening, diagnosis, treatment, and monitoring of metabolic dysfunction-associated steatotic liver disease.
Dr Abdelmalek reviews her approach to screening, diagnosis, treatment, and monitoring of metabolic dysfunction-associated steatotic liver disease.
Dr Abdelmalek reviews her...
07/13/2026
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Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
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A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
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Robert Fontana
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Robert Fontana, MD, on Collaborative Care for MASLD and MASH
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Dr Fontana recaps his presentation at Digestive Disease Week 2026 on advances in diagnosis and treatment for patients with MASLD and MASH, and the importance of collaboration among specialties as the numbers of patients with these conditions...
Dr Fontana recaps his presentation at Digestive Disease Week 2026 on advances in diagnosis and treatment for patients with MASLD and MASH, and the importance of collaboration among specialties as the numbers of patients with these conditions...
Dr Fontana recaps his...
06/01/2026
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RESEARCH INSIGHTS
Rising MASLD Prevalence in Younger Adults Linked to Increased Mortality Risk
05/15/2026
Jessica Garlewicz
Importantly, MASLD was linked to increased all-cause mortality in young adults, driven primarily by cardiovascular and metabolic causes.
Importantly, MASLD was linked to increased all-cause mortality in young adults, driven primarily by cardiovascular and metabolic causes.
Importantly, MASLD was linked to...
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FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
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FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
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Research Insights
IBS-C Microbiome Signatures Offer Insights Into Parkinson’s-Related Constipation
06/09/2026
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New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
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Research Review
Colonoscopy Associated With Lower Colorectal Cancer Risk in Adults Aged 40–49 Years
06/03/2026
Jessica Garlewicz
Investigators observed a lower cumulative incidence of CRC among individuals who underwent colonoscopy across both age groups studied.
Investigators observed a lower cumulative incidence of CRC among individuals who underwent colonoscopy across both age groups studied.
Investigators observed a lower...
06/03/2026
Gastroenterology
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Early-Onset Colorectal Cancer Survivors Report Persistent Sexual Health Challenges
05/27/2026
Rebecca Mashaw
A new study adds to growing evidence that sexual and reproductive health issues are common yet frequently overlooked among younger colorectal cancer survivors.
A new study adds to growing evidence that sexual and reproductive health issues are common yet frequently overlooked among younger colorectal cancer survivors.
A new study adds to growing...
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Research Review
Synchronous Colon Cancer Not Associated With Worse Survival in Stage I–III Disease
05/27/2026
Jessica Garlewicz
The findings provide reassurance regarding prognosis in patients presenting with multiple primary tumors.
The findings provide reassurance regarding prognosis in patients presenting with multiple primary tumors.
The findings provide reassurance...
05/27/2026
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High Rehospitalization and Mortality Rates Persist After ICI-Associated Colitis
05/06/2026
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Rehospitalization remained common among patients who experienced immune checkpoint inhibitor-associated colitis, indicating that adverse effects often persist beyond ICI exposure.
Rehospitalization remained common among patients who experienced immune checkpoint inhibitor-associated colitis, indicating that adverse effects often persist beyond ICI exposure.
Rehospitalization remained...
05/06/2026
Gastroenterology
Research Highlights
MAPI Offers New Biomarker in Screening for MetALD and ALD
04/23/2026
Jessica Garlewicz
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index...
04/23/2026
Gastroenterology
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Lifetime Alcohol Intake Linked to Colorectal Cancer Risk
02/11/2026
Jessica Garlewicz
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key...
02/11/2026
Gastroenterology
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
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Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology

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