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Irritable Bowel Syndrome-C

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Research Review
Global Study Finds Distinct Abdominal Pain Profiles Across IBS Subtypes, Most Severe in IBS-C
10/07/2026
Rebecca Mashaw
The multinational analysis adds detail to how abdominal pain presents across Rome IV IBS subtypes and concludes that patients with constipation-predominant IBS have more pain for longer periods.
The multinational analysis adds detail to how abdominal pain presents across Rome IV IBS subtypes and concludes that patients with constipation-predominant IBS have more pain for longer periods.
The multinational analysis adds...
10/07/2026
Gastroenterology
Consensus Statement
Consensus Panel Defines Patient-Centered Treatment Response to IBS-C
09/09/2026
Rebecca Mashaw
The authors highlighted the continuing need for practical tools to support individualized treatment decisions and reduce variability in clinical management of constipation-dominant irritable bowel syndrome.
The authors highlighted the continuing need for practical tools to support individualized treatment decisions and reduce variability in clinical management of constipation-dominant irritable bowel syndrome.
The authors highlighted the...
09/09/2026
Gastroenterology
Research Highlights
Tenapanor Linked to Earlier, Sustained Symptom Relief in IBS-C
07/23/2026
Rebecca Mashaw
A novel post hoc analysis demonstrates that tenapanor reduces the time to first response in irritable bowel syndrome with constipation compared to placebo.
A novel post hoc analysis demonstrates that tenapanor reduces the time to first response in irritable bowel syndrome with constipation compared to placebo.
A novel post hoc analysis...
07/23/2026
Gastroenterology
Research Review
IBS-C Review Emphasizes Multisymptom Management Beyond Constipation and Pain
07/15/2026
Rebecca Mashaw
A narrative review synthesizes current evidence on diagnosis of constipation-dominant IBS, its differentiation from chronic idiopathic constipation (CIC), and pharmacologic and nonpharmacologic approaches that target multiple gastrointestinal...
A narrative review synthesizes current evidence on diagnosis of constipation-dominant IBS, its differentiation from chronic idiopathic constipation (CIC), and pharmacologic and nonpharmacologic approaches that target multiple gastrointestinal...
A narrative review synthesizes...
07/15/2026
Gastroenterology
Research Review
Tenapanor Improves IBS-C Symptoms in Systematic Review and Meta-Analysis
07/15/2026
Rebecca Mashaw
A recent systematic review and meta-analysis concluded that tenapanor is effective for IBS-C symptom management but investigators emphasized the need for additional studies to evaluate its long-term safety.
A recent systematic review and meta-analysis concluded that tenapanor is effective for IBS-C symptom management but investigators emphasized the need for additional studies to evaluate its long-term safety.
A recent systematic review and...
07/15/2026
Gastroenterology
Research Insights
IBS-C Microbiome Signatures Offer Insights Into Parkinson’s-Related Constipation
06/09/2026
Rebecca Mashaw
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
Gastroenterology
Research Highlights
Sexual Dysfunction Common Among Women With IBS-C, CIC
05/15/2026
Rebecca Mashaw
A recent study presented at DDW 2026 challenges assumptions that sexual dysfunction in IBS-C and other constipation-related disorders is directly tied to vaginal pain or higher pelvic floor tone.
A recent study presented at DDW 2026 challenges assumptions that sexual dysfunction in IBS-C and other constipation-related disorders is directly tied to vaginal pain or higher pelvic floor tone.
A recent study presented at DDW...
05/15/2026
Gastroenterology
Research Review
IBS-C Treatment Changes Linked to Higher GI Healthcare Utilization
05/15/2026
Rebecca Mashaw
An analysis presented at Digestive Disease Week 2026 underscores the importance of long-term, patient-centered IBS-C management strategies aimed at improving therapeutic persistence and reducing avoidable healthcare utilization in routine...
An analysis presented at Digestive Disease Week 2026 underscores the importance of long-term, patient-centered IBS-C management strategies aimed at improving therapeutic persistence and reducing avoidable healthcare utilization in routine...
An analysis presented at...
05/15/2026
Gastroenterology
Expert Insights
The "Dream Team" for Managing IBS-C Needs GI Psychologist and Dietician
03/11/2026
Megan Riehl, PsyD; Kate Scarlata, RDN
GI psychologist Megan Riehl and registered dietician and nutritionist Kate Scarlata discuss how their specialty care can help patients with constipation-predominant irritable bowel syndrome and which patients are the best candidates for...
GI psychologist Megan Riehl and registered dietician and nutritionist Kate Scarlata discuss how their specialty care can help patients with constipation-predominant irritable bowel syndrome and which patients are the best candidates for...
GI psychologist Megan Riehl and...
03/11/2026
Gastroenterology
Research Review
Inconsistent Diagnostic Criteria for IBS-C and Functional Constipation Identified in Global Guidelines
02/13/2026
Rebecca Mashaw
A global review found marked inconsistencies in diagnostic criteria for IBS-C and functional constipation across clinical practice guidelines, underscoring the need for harmonized, evidence-based standards to improve diagnosis and patient...
A global review found marked inconsistencies in diagnostic criteria for IBS-C and functional constipation across clinical practice guidelines, underscoring the need for harmonized, evidence-based standards to improve diagnosis and patient...
A global review found marked...
02/13/2026
Gastroenterology
Hilary Ugras
Clinical Pearls
Hilary Ugras, NP, on IBS-C Medical Therapies
01/21/2026
Hilary Ugras, NP
Hilary Ugras, NP, reviews the types of medical therapies available for treating IBS-C and how to position them in treating patients.
Hilary Ugras, NP, reviews the types of medical therapies available for treating IBS-C and how to position them in treating patients.
Hilary Ugras, NP, reviews the...
01/21/2026
Gastroenterology

Expert Insights

Expert Insights
The "Dream Team" for Managing IBS-C Needs GI Psychologist and Dietician
03/11/2026
Megan Riehl, PsyD; Kate Scarlata, RDN
GI psychologist Megan Riehl and registered dietician and nutritionist Kate Scarlata discuss how their specialty care can help patients with constipation-predominant irritable bowel syndrome and which patients are the best candidates for...
GI psychologist Megan Riehl and registered dietician and nutritionist Kate Scarlata discuss how their specialty care can help patients with constipation-predominant irritable bowel syndrome and which patients are the best candidates for...
GI psychologist Megan Riehl and...
03/11/2026
Gastroenterology
Hilary Ugras
Clinical Pearls
Hilary Ugras, NP, on IBS-C Medical Therapies
01/21/2026
Hilary Ugras, NP
Hilary Ugras, NP, reviews the types of medical therapies available for treating IBS-C and how to position them in treating patients.
Hilary Ugras, NP, reviews the types of medical therapies available for treating IBS-C and how to position them in treating patients.
Hilary Ugras, NP, reviews the...
01/21/2026
Gastroenterology
Kim Orleck
Clinical Pearls
Kimberly Orleck, PA, on Diagnosing IBS-C
01/13/2026
Kimberly Orleck, ANP-BC
Kimberly Orleck, ANP-BC, reviews the key points to consider when diagnosing a patient with constipation to determine if the condition is irritable bowel syndrome with predominant constipation.
Kimberly Orleck, ANP-BC, reviews the key points to consider when diagnosing a patient with constipation to determine if the condition is irritable bowel syndrome with predominant constipation.
Kimberly Orleck, ANP-BC, reviews...
01/13/2026
Gastroenterology
Lin Chang
Conference Coverage
Lin Chang, MD, on What's New in Rome V
10/20/2026
Lin Chang, MD
Dr Chang reviews important changes in the Rome V diagnostic criteria for disorders of gut-brain interaction, which she detailed during her lecture at the American College of Gastroenterology Scientific Meeting in Nashville, October 12-14.
Dr Chang reviews important changes in the Rome V diagnostic criteria for disorders of gut-brain interaction, which she detailed during her lecture at the American College of Gastroenterology Scientific Meeting in Nashville, October 12-14.
Dr Chang reviews important...
10/20/2026
Gastroenterology
Expert Insights
Diagnosis and Monitoring in MASLD/MASH
10/16/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
Drs Fontana, Abdelmalek, and Arab review potential confounders for liver stiffness tests—from food or alcohol to even a cup of coffee—and the best methods to use for both diagnosis and continued monitoring for patients with MASLD or MASH,...
Drs Fontana, Abdelmalek, and Arab review potential confounders for liver stiffness tests—from food or alcohol to even a cup of coffee—and the best methods to use for both diagnosis and continued monitoring for patients with MASLD or MASH,...
Drs Fontana, Abdelmalek, and...
10/16/2026
Gastroenterology
Expert Insights
Fibrosis and Steatosis in MASLD/MASH
10/16/2026
Robert Fontana, MD; Juan Pablo Arab, MD; Manal Abdelmalek, MD
Our expert panel continues this series on MASLD and MASH, discussing how best to diagnose and quantify fibrosis through FIB-4, VCTE, MRE and other blood and imaging tests.
Our expert panel continues this series on MASLD and MASH, discussing how best to diagnose and quantify fibrosis through FIB-4, VCTE, MRE and other blood and imaging tests.
Our expert panel continues this...
10/16/2026
Gastroenterology
Conference Coverage
Folasade May, MD, on What's Driving Early Onset Colorectal Cancer
10/13/2026
Folasade May, MD, PhD
Dr Fola May of UCLA Health discusses her presentation at the ACG Scientific Meeting on the concerning rise in colorectal cancers among patients under 45 and some of the factors being investigated as possible contributors, from genetics and...
Dr Fola May of UCLA Health discusses her presentation at the ACG Scientific Meeting on the concerning rise in colorectal cancers among patients under 45 and some of the factors being investigated as possible contributors, from genetics and...
Dr Fola May of UCLA Health...
10/13/2026
Gastroenterology
Expert Insights
MASLD, MetALD, ALD: Defining Conditions
10/12/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
Hepatologists Robert Fontana, MD, Manal Abdelmalek, MD, and JP Arab, MD, clarify how MASLD differs from MetALD and ALD, and how amounts of alcohol consumed can lead to progression of fibrosis.
Hepatologists Robert Fontana, MD, Manal Abdelmalek, MD, and JP Arab, MD, clarify how MASLD differs from MetALD and ALD, and how amounts of alcohol consumed can lead to progression of fibrosis.
Hepatologists Robert Fontana,...
10/12/2026
Gastroenterology
Expert Insights
MASLD/MASH Roundtable: Defining and Assessing Obesity
10/12/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
Three eminent hepatologists expert in the diagnosis, treatment, and management of MASLD and MASH start off a series of roundtable talks on these conditions by reviewing changes in the definition and assessment of obesity--a key issue in the...
Three eminent hepatologists expert in the diagnosis, treatment, and management of MASLD and MASH start off a series of roundtable talks on these conditions by reviewing changes in the definition and assessment of obesity--a key issue in the...
Three eminent hepatologists...
10/12/2026
Gastroenterology
Conference Coverage
Food Allergies or Sensitivity? Brian Lacy, MD, Explains
10/12/2026
Brian E. Lacy, PhD, MD
Dr Lacy reviews the diagnostic signs of true food allergies, including anaphylaxis, versus food sensitivities that may cause gastric symptoms.
Dr Lacy reviews the diagnostic signs of true food allergies, including anaphylaxis, versus food sensitivities that may cause gastric symptoms.
Dr Lacy reviews the diagnostic...
10/12/2026
Gastroenterology
Conference Coverage
AI Will Not Replace Doctors: Brennan Spiegel, MD, on 'Blended Intelligence.'
10/11/2026
Brennan Spiegel, MD
Dr Spiegel recaps his Trailblazer address at ACG on the prospect of developing a 'blended intelligence' that accesses the wealth of information available through artificial intelligence with the human wisdom, experience, and abilities of...
Dr Spiegel recaps his Trailblazer address at ACG on the prospect of developing a 'blended intelligence' that accesses the wealth of information available through artificial intelligence with the human wisdom, experience, and abilities of...
Dr Spiegel recaps his...
10/11/2026
Gastroenterology
Gut Check logo
Expert Insights
Gut Check: Andrea Shin, MD, on Rome V Criteria for Bowel Disorders
10/08/2026
Brian E. Lacy, PhD, MD; Andrea Shin, MD
Dr Lacy hosts Dr Andrea Shin to discuss the changes in criteria from Rome IV to Rome V for bowel disorders of gut-brain interaction, including IBS, chronic constipation, and chronic diarrhea.
Dr Lacy hosts Dr Andrea Shin to discuss the changes in criteria from Rome IV to Rome V for bowel disorders of gut-brain interaction, including IBS, chronic constipation, and chronic diarrhea.
Dr Lacy hosts Dr Andrea Shin to...
10/08/2026
Gastroenterology
Gut Check logo
Expert Insights
Gut Check: Hans Törnblom, MD, on Gastroduodenal Disorders
08/19/2026
Brian E. Lacy, PhD, MD; Hans Törnblom, MD
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised...
08/19/2026
Gastroenterology

News

Research Review
Inconsistent Diagnostic Criteria for IBS-C and Functional Constipation Identified in Global Guidelines
02/13/2026
Rebecca Mashaw
A global review found marked inconsistencies in diagnostic criteria for IBS-C and functional constipation across clinical practice guidelines, underscoring the need for harmonized, evidence-based standards to improve diagnosis and patient...
A global review found marked inconsistencies in diagnostic criteria for IBS-C and functional constipation across clinical practice guidelines, underscoring the need for harmonized, evidence-based standards to improve diagnosis and patient...
A global review found marked...
02/13/2026
Gastroenterology
Research Highlights
Gut Microbiota and SCFA Alterations Identified in IBS-C Patients
01/15/2026
Rebecca Mashaw
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial...
01/15/2026
Gastroenterology
Research Insights
Standard-Dose Regimens Achieve High Eradication Rates in H. pylori Treatment
06/11/2026
Jessica Garlewicz
Across regimens, increasing bismuth or antibiotic doses beyond these thresholds did not improve outcomes.
Across regimens, increasing bismuth or antibiotic doses beyond these thresholds did not improve outcomes.
Across regimens, increasing...
06/11/2026
Gastroenterology
Research Highlights
Nonantibiotic Medications Contribute to CDI Risk
06/05/2026
Rebecca Mashaw
Corticosteroids, proton pump inhibitors, and antidepressants were found to be associated with increased risks of contracting Clostrioides diffiicile infection, researchers reported.
Corticosteroids, proton pump inhibitors, and antidepressants were found to be associated with increased risks of contracting Clostrioides diffiicile infection, researchers reported.
Corticosteroids, proton pump...
06/05/2026
Gastroenterology
Research Summary
CRC Risk Diverges After Positive FOBT Based on Colonoscopy Follow-Up
06/03/2026
Jessica Garlewicz
The findings suggest that a negative colonoscopy confers a sustained protective effect and may inform individualized screening intervals.
The findings suggest that a negative colonoscopy confers a sustained protective effect and may inform individualized screening intervals.
The findings suggest that a...
06/03/2026
Gastroenterology
FDA Approval
FDA Approves Bulevirtide for Hepatitis D Treatment
06/01/2026
Rebecca Mashaw
The approval provides the first FDA-approved treatment option specifically indicated for chronic HDV infection, addressing a substantial unmet medical need in hepatology.
The approval provides the first FDA-approved treatment option specifically indicated for chronic HDV infection, addressing a substantial unmet medical need in hepatology.
The approval provides the first...
06/01/2026
Gastroenterology
Research Review
Colon Cancer Mortality Declines Reverse After 2013
05/29/2026
Jessica Garlewicz
Data indicate that while overall mortality from colorectal cancer has declined over the past 30 years, the rate increased from 2013 to 2023 and may continue to rise through 2040.
Data indicate that while overall mortality from colorectal cancer has declined over the past 30 years, the rate increased from 2013 to 2023 and may continue to rise through 2040.
Data indicate that while overall...
05/29/2026
Gastroenterology
Guideline Update
American Cancer Society Updates Colorectal Cancer Screening Guidance for Adults
05/29/2026
Rebecca Mashaw
The update emphasizes that offering several validated screening options can improve adherence because “the most effective screening test is the one that the patient completes.”
The update emphasizes that offering several validated screening options can improve adherence because “the most effective screening test is the one that the patient completes.”
The update emphasizes that...
05/29/2026
Gastroenterology
Research Highlights
Colonoscopy Timing After Positive FIT May Be Less Critical Than Ensuring Completion
05/27/2026
Jessica Garlewicz
Ensuring completion of follow-up colonoscopy may be more important than strict adherence to short time intervals between a positive FIT and the scoping procedure.
Ensuring completion of follow-up colonoscopy may be more important than strict adherence to short time intervals between a positive FIT and the scoping procedure.
Ensuring completion of follow-up...
05/27/2026
Gastroenterology
FDA Alert
FDA Approves Linerixibat for Pruritis in PBC
03/20/2026
Rebecca Mashaw
The US Food and Drug Administration (FDA) on March 19 approved linerixibat for the treatment of cholestatic pruritus in adult patients with PBC. The ileal bile acid transporter (IBAT) inhibitor reduces multiple drivers of chronic itch, which...
The US Food and Drug Administration (FDA) on March 19 approved linerixibat for the treatment of cholestatic pruritus in adult patients with PBC. The ileal bile acid transporter (IBAT) inhibitor reduces multiple drivers of chronic itch, which...
The US Food and Drug...
03/20/2026
Gastroenterology
Research Highlights
Dynamic FIB-4 Changes Track Fibrosis Progression and Predict Outcomes in MASLD
03/18/2026
Jessica Garlewicz
Findings of a recent analysis suggest that serial FIB-4 monitoring may provide prognostic value beyond a single baseline measurement.
Findings of a recent analysis suggest that serial FIB-4 monitoring may provide prognostic value beyond a single baseline measurement.
Findings of a recent analysis...
03/18/2026
Gastroenterology
Research Highlights
Colonic Microbiota Dysbiosis Tied to IBS-C Pathophysiology
03/18/2026
Rebecca Mashaw
Colonic microbiota dysbiosis appears central to IBS-C pathophysiology, affecting motility, inflammation, and gut-brain interactions.
Colonic microbiota dysbiosis appears central to IBS-C pathophysiology, affecting motility, inflammation, and gut-brain interactions.
Colonic microbiota dysbiosis...
03/18/2026
Gastroenterology

Interactive Features

doc with stethoscope
Poll
Multidisciplinary Care in GI Recovery
01/09/2024
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal...
01/09/2024
Gastroenterology
light bulb+idea+thinking+poll
Poll
Gastro Issues Post-COVID-19
01/10/2023
Regardless of ICU status, nearly 1 in 5 US patients hospitalized with COVID-19 have experienced gastrointestinal symptoms in some form, a multicenter cohort study confirmed. Which of the following issues have you seen among your patients who...
Regardless of ICU status, nearly 1 in 5 US patients hospitalized with COVID-19 have experienced gastrointestinal symptoms in some form, a multicenter cohort study confirmed. Which of the following issues have you seen among your patients who...
Regardless of ICU status, nearly...
01/10/2023
Gastroenterology
opioids with prescription
Poll
Is Vonoprazan Effective for Erosive Esophagitis?
01/09/2023
For patients with severe acid reflux disease, do you prefer vonoprazan, lansoprazole, or a different medication? Answer our poll to voice your preference!
For patients with severe acid reflux disease, do you prefer vonoprazan, lansoprazole, or a different medication? Answer our poll to voice your preference!
For patients with severe acid...
01/09/2023
Gastroenterology
Wine
Poll
Diet and Added Risk of CRC
03/22/2022
Diet plays an important role in risk of colorectal cancer. How do you manage diet with your patients? Tell us with this quick poll!
Diet plays an important role in risk of colorectal cancer. How do you manage diet with your patients? Tell us with this quick poll!
Diet plays an important role in...
03/22/2022
Gastroenterology
Hospital
Quiz
Adverse Events Among Patients With HVB and Covid-19 Coinfection
09/08/2021
Research suggests a SARS‐CoV‐2 and HBV coinfection may increase adverse events at the onset of the virus. Have you seen this in your practice? Tell us with this quick poll.
Research suggests a SARS‐CoV‐2 and HBV coinfection may increase adverse events at the onset of the virus. Have you seen this in your practice? Tell us with this quick poll.
Research suggests a SARS‐CoV‐2...
09/08/2021
Gastroenterology
Stethoscope
Poll
Recommended Chemoprevention for Colorectal Cancer
08/27/2021
Do you advise your patients to use either or both of these medications as chemoprevention for colorectal cancer? Take our quick poll and let us know!
Do you advise your patients to use either or both of these medications as chemoprevention for colorectal cancer? Take our quick poll and let us know!
Do you advise your patients to...
08/27/2021
Gastroenterology
blood in test tube
Poll
Lowering HCC Risk in Patients With Chronic HBV
07/02/2021
What medications do you rely on when treating patients with chronic hepatitis B? Tell us with this quick poll!
What medications do you rely on when treating patients with chronic hepatitis B? Tell us with this quick poll!
What medications do you rely on...
07/02/2021
Gastroenterology
doc in mask
Poll
Statins Prior to Surgical Resection Reduce Mortality Rate
06/01/2021
Would you prescribe a statin to your patients with rectal cancer? Take our poll and let us know!
Would you prescribe a statin to your patients with rectal cancer? Take our poll and let us know!
Would you prescribe a statin to...
06/01/2021
Gastroenterology
Doctor
Poll
Liver Disease and CVD
07/15/2020
It has been unclear whether nonalcoholic fatty liver disease is directly related to cardiovascular disease or whether this relationship is confounded by metabolic factors of NAFLD and CVD. What do you think?
It has been unclear whether nonalcoholic fatty liver disease is directly related to cardiovascular disease or whether this relationship is confounded by metabolic factors of NAFLD and CVD. What do you think?
It has been unclear whether...
07/15/2020
Gastroenterology
Poll
Poll: Opioid Use and Constipation
01/23/2020
Do you often evaluate defecation function among patients with constipation who are on opioids or were recently on opioids? Let us know by taking the poll!
Do you often evaluate defecation function among patients with constipation who are on opioids or were recently on opioids? Let us know by taking the poll!
Do you often evaluate defecation...
01/23/2020
Gastroenterology

News

Research Insights
IBS-C Microbiome Signatures Offer Insights Into Parkinson’s-Related Constipation
06/09/2026
Rebecca Mashaw
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
Gastroenterology
News
Vonoprazan-Tetracycline Dual Therapy Shows Noninferior H. pylori Eradication
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
Updated Guideline Recommends Selective Antibiotic Use for Outpatient Diverticulitis Management
09/08/2026
Jessica Garlewicz
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline...
09/08/2026
Gastroenterology
News
Low-Dose Gluten Exposure Triggers Immune Activation in Treated Celiac Disease Despite Minimal Symptoms
09/08/2026
Jessica Garlewicz
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten...
09/08/2026
Gastroenterology
News
Combined H. pylori and FIT Screening Found Cost-Effective for Long-Term Cancer Prevention
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
News
Celiac Disease Associated With Nearly 3-Fold Higher Risk of Solid Organ Transplantation
09/08/2026
Jessica Garlewicz
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease...
09/08/2026
Gastroenterology
News
Refined Fibrosis Screening Criteria Reduce Eligible Population, Improve Detection of Advanced Liver Disease
09/08/2026
Jessica Garlewicz
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening...
09/08/2026
Gastroenterology
News
Menopause May Help Explain Age-Related Fibrosis Risk in Women With MASLD
09/08/2026
Jessica Garlewicz
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate...
09/08/2026
Gastroenterology
FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Insights
IBS-C Microbiome Signatures Offer Insights Into Parkinson’s-Related Constipation
06/09/2026
Rebecca Mashaw
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
Gastroenterology

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