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Colorectal Cancer

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Conference Coverage
Multilevel Intervention Improves CRC Screening Rates
11/09/2026
Rebecca Mashaw
Aasma Shaukat, MD, presented an award-winning abstract on interventions that increased colorectal cancer screening rates at federally qualified health care centers.
Aasma Shaukat, MD, presented an award-winning abstract on interventions that increased colorectal cancer screening rates at federally qualified health care centers.
Aasma Shaukat, MD, presented an...
11/09/2026
Gastroenterology
FDA Approval
FDA Grants Accelerated Approval to Dostarlimab for MSI-H/dMMR Rectal Cancer
10/20/2026
Rebecca Mashaw
Of 154 treated patients, 110 (71%) were treated with dostarlimab alone, did not receive any additional form of treatment, and did not experience disease progression of Stage II/III locally advanced rectal cancer.
Of 154 treated patients, 110 (71%) were treated with dostarlimab alone, did not receive any additional form of treatment, and did not experience disease progression of Stage II/III locally advanced rectal cancer.
Of 154 treated patients, 110...
10/20/2026
Gastroenterology
Conference Coverage
Early-Onset Colon and Rectal Cancers Show Distinct Patterns in US Inpatients
10/13/2026
Rebecca Mashaw
Colon and rectal cancers were shown to differ in clinical presentation and associated conditions among younger inpatients, according to research that won an ACG Presidential Poster Award at the annual scientific meeting.
Colon and rectal cancers were shown to differ in clinical presentation and associated conditions among younger inpatients, according to research that won an ACG Presidential Poster Award at the annual scientific meeting.
Colon and rectal cancers were...
10/13/2026
Gastroenterology
Conference Coverage
FIT CRC Screening Performance Differs by Sex
10/13/2026
Rebecca Mashaw
Results of a study presented at the ACG Scientific Conference provide evidence for evaluating sex-specific FIT thresholds, with the appropriate choice tied to the intended screening goal, investigators concluded.
Results of a study presented at the ACG Scientific Conference provide evidence for evaluating sex-specific FIT thresholds, with the appropriate choice tied to the intended screening goal, investigators concluded.
Results of a study presented at...
10/13/2026
Gastroenterology
Research Highlights
Barriers to FIT Completion Persist Among Asian American Patients
09/25/2026
Jessica Garlewicz
Despite a high level of awareness of the importance of screening for colorectal cancer, participation in fecal immunochemical testing remained low among Asian-Americans according to a recent survey.
Despite a high level of awareness of the importance of screening for colorectal cancer, participation in fecal immunochemical testing remained low among Asian-Americans according to a recent survey.
Despite a high level of...
09/25/2026
Gastroenterology
Research Summary
WhatsApp Chatbot Outreach Improves CRC Screening Uptake
09/15/2026
Jessica Garlewicz
A WhatsApp outreach intervention improved CRC screening uptake at 3 months, with supportive findings at 6-months, over standard text message reminders.
A WhatsApp outreach intervention improved CRC screening uptake at 3 months, with supportive findings at 6-months, over standard text message reminders.
A WhatsApp outreach intervention...
09/15/2026
Gastroenterology
Research Highlights
Modeling Study Compares Clinical and Economic Performance of CRC Screening Tests
09/15/2026
Jessica Garlewicz
Economic analyses demonstrated that FIT, at an assumed cost of $25 per test, was the most cost-effective overall screening strategy across all adherence levels.
Economic analyses demonstrated that FIT, at an assumed cost of $25 per test, was the most cost-effective overall screening strategy across all adherence levels.
Economic analyses demonstrated...
09/15/2026
Gastroenterology
Research Summary
FIT Screening Participation Stabilizes After Initial Round, Meta-Analysis Finds
09/01/2026
Rebecca Mashaw
Across the included studies, 47.1% of individuals were classified as consistent screeners, participating in every screening round.
Across the included studies, 47.1% of individuals were classified as consistent screeners, participating in every screening round.
Across the included studies,...
09/01/2026
Gastroenterology
Research Highlights
County-Level Analysis Reveals Persistent Racial and Ethnic Disparities in Colorectal Cancer Mortality
08/27/2026
Riya Gandhi, MA
While declines were observed across all racial and ethnic groups, Black males aged 45 years or older continued to have the highest CRC mortality rate in 2019, researchers found.
While declines were observed across all racial and ethnic groups, Black males aged 45 years or older continued to have the highest CRC mortality rate in 2019, researchers found.
While declines were observed...
08/27/2026
Gastroenterology
Research Review
FIT-Based Screening Associated With Major CRC Mortality Decline
08/27/2026
Riya Gandhi, MA
The findings of a large cohort study from Spain support the long-term benefit of organized fecal immunochemical test-based screening programs as a public health strategy to reduce colorectal cancer mortality.
The findings of a large cohort study from Spain support the long-term benefit of organized fecal immunochemical test-based screening programs as a public health strategy to reduce colorectal cancer mortality.
The findings of a large cohort...
08/27/2026
Gastroenterology
FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology

News

FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Summary
CRC Risk Diverges After Positive FOBT Based on Colonoscopy Follow-Up
06/03/2026
Jessica Garlewicz
The findings suggest that a negative colonoscopy confers a sustained protective effect and may inform individualized screening intervals.
The findings suggest that a negative colonoscopy confers a sustained protective effect and may inform individualized screening intervals.
The findings suggest that a...
06/03/2026
Gastroenterology
Research Review
Colonoscopy Associated With Lower Colorectal Cancer Risk in Adults Aged 40–49 Years
06/03/2026
Jessica Garlewicz
Investigators observed a lower cumulative incidence of CRC among individuals who underwent colonoscopy across both age groups studied.
Investigators observed a lower cumulative incidence of CRC among individuals who underwent colonoscopy across both age groups studied.
Investigators observed a lower...
06/03/2026
Gastroenterology
Research Review
Colon Cancer Mortality Declines Reverse After 2013
05/29/2026
Jessica Garlewicz
Data indicate that while overall mortality from colorectal cancer has declined over the past 30 years, the rate increased from 2013 to 2023 and may continue to rise through 2040.
Data indicate that while overall mortality from colorectal cancer has declined over the past 30 years, the rate increased from 2013 to 2023 and may continue to rise through 2040.
Data indicate that while overall...
05/29/2026
Gastroenterology
Guideline Update
American Cancer Society Updates Colorectal Cancer Screening Guidance for Adults
05/29/2026
Rebecca Mashaw
The update emphasizes that offering several validated screening options can improve adherence because “the most effective screening test is the one that the patient completes.”
The update emphasizes that offering several validated screening options can improve adherence because “the most effective screening test is the one that the patient completes.”
The update emphasizes that...
05/29/2026
Gastroenterology
Research Insights
Early-Onset Colorectal Cancer Survivors Report Persistent Sexual Health Challenges
05/27/2026
Rebecca Mashaw
A new study adds to growing evidence that sexual and reproductive health issues are common yet frequently overlooked among younger colorectal cancer survivors.
A new study adds to growing evidence that sexual and reproductive health issues are common yet frequently overlooked among younger colorectal cancer survivors.
A new study adds to growing...
05/27/2026
Gastroenterology
Research Review
Synchronous Colon Cancer Not Associated With Worse Survival in Stage I–III Disease
05/27/2026
Jessica Garlewicz
The findings provide reassurance regarding prognosis in patients presenting with multiple primary tumors.
The findings provide reassurance regarding prognosis in patients presenting with multiple primary tumors.
The findings provide reassurance...
05/27/2026
Gastroenterology
Research Highlights
Colonoscopy Timing After Positive FIT May Be Less Critical Than Ensuring Completion
05/27/2026
Jessica Garlewicz
Ensuring completion of follow-up colonoscopy may be more important than strict adherence to short time intervals between a positive FIT and the scoping procedure.
Ensuring completion of follow-up colonoscopy may be more important than strict adherence to short time intervals between a positive FIT and the scoping procedure.
Ensuring completion of follow-up...
05/27/2026
Gastroenterology
Research Review
FIT Screening Outcomes Stabilize After Initial Round but Remain Clinically Relevant Over Time
02/17/2026
Jessica Garlewicz
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight...
02/17/2026
Gastroenterology
News
Lifetime Alcohol Intake Linked to Colorectal Cancer Risk
02/11/2026
Jessica Garlewicz
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key...
02/11/2026
Gastroenterology
News
Vonoprazan-Tetracycline Dual Therapy Shows Noninferior H. pylori Eradication
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
Updated Guideline Recommends Selective Antibiotic Use for Outpatient Diverticulitis Management
09/08/2026
Jessica Garlewicz
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline...
09/08/2026
Gastroenterology
News
Low-Dose Gluten Exposure Triggers Immune Activation in Treated Celiac Disease Despite Minimal Symptoms
09/08/2026
Jessica Garlewicz
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten...
09/08/2026
Gastroenterology
News
Combined H. pylori and FIT Screening Found Cost-Effective for Long-Term Cancer Prevention
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
News
Celiac Disease Associated With Nearly 3-Fold Higher Risk of Solid Organ Transplantation
09/08/2026
Jessica Garlewicz
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease...
09/08/2026
Gastroenterology
News
Refined Fibrosis Screening Criteria Reduce Eligible Population, Improve Detection of Advanced Liver Disease
09/08/2026
Jessica Garlewicz
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening...
09/08/2026
Gastroenterology
News
Menopause May Help Explain Age-Related Fibrosis Risk in Women With MASLD
09/08/2026
Jessica Garlewicz
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate...
09/08/2026
Gastroenterology
FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Insights
Standard-Dose Regimens Achieve High Eradication Rates in H. pylori Treatment
06/11/2026
Jessica Garlewicz
Across regimens, increasing bismuth or antibiotic doses beyond these thresholds did not improve outcomes.
Across regimens, increasing bismuth or antibiotic doses beyond these thresholds did not improve outcomes.
Across regimens, increasing...
06/11/2026
Gastroenterology

Quiz

Quiz
Terminal Ileal Resection and CRC Risk
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
How Does Stool-Based CRC Surveillance Compare to Colonoscopy?
07/21/2025
Rebecca Mashaw
07/21/2025
Gastroenterology
Quiz
How Does CRC Affect Sexual Health in Women Over 40?
07/21/2025
Rebecca Mashaw
07/21/2025
Gastroenterology
Quiz
What Improves FIT Return Rates?
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
What Predicts Adherence to mt-sDNA Screening?
07/16/2025
Riya Gandhi, MA
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive...
07/16/2025
Gastroenterology
Quiz
Why Was CRC Screening Expanded to Ages 45–49?
07/15/2025
Riya Gandhi, MA
Are you up to date on the rationale for younger screening initiation? Take this quiz to explore the epidemiologic trends that influenced new CRC guidelines.
Are you up to date on the rationale for younger screening initiation? Take this quiz to explore the epidemiologic trends that influenced new CRC guidelines.
Are you up to date on the...
07/15/2025
Gastroenterology
Quiz
Dietary Contributors to Deaths From Colorectal Cancer
05/22/2025
Rebecca Mashaw
Do you know the dietary factors contributed the most to deaths from colorectal cancer in the G20 nations during 2021? Our quick quiz will answer that question!
Do you know the dietary factors contributed the most to deaths from colorectal cancer in the G20 nations during 2021? Our quick quiz will answer that question!
Do you know the dietary factors...
05/22/2025
Gastroenterology
Quiz
Dietary Factors in Colorectal Cancer
12/06/2024
Rebecca Mashaw
What dietary factors contributed most to deaths from colorectal cancer? Take our quiz to find out!
What dietary factors contributed most to deaths from colorectal cancer? Take our quiz to find out!
What dietary factors contributed...
12/06/2024
Gastroenterology
Quiz
Risk Stratification for Colorectal Cancer
12/03/2024
Riya Gandhi, MA
Which of the following screening guidelines are recommended for patients with a familial history of colorectal cancer? Take our quiz to find out.
Which of the following screening guidelines are recommended for patients with a familial history of colorectal cancer? Take our quiz to find out.
Which of the following screening...
12/03/2024
Gastroenterology
Quiz
Colorectal Cancer Risk in Diverticulitis
11/29/2024
Rebecca Mashaw
Do patients with diverticulitis need more frequent screenings for colorectal cancer? Take our quiz to find out.
Do patients with diverticulitis need more frequent screenings for colorectal cancer? Take our quiz to find out.
Do patients with diverticulitis...
11/29/2024
Gastroenterology
Quiz
Diagnostic Complexity in Refractory GERD
08/07/2025
Rebecca Mashaw
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a...
08/07/2025
Gastroenterology
Quiz
Terminal Ileal Resection and CRC Risk
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
DGBIs and GERD
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
Prevalence of Overlapping Esophageal DGBIs and GERD in Patients With Refractory Reflux
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Quiz
How Does Stool-Based CRC Surveillance Compare to Colonoscopy?
07/21/2025
Rebecca Mashaw
07/21/2025
Gastroenterology
Quiz
How Does CRC Affect Sexual Health in Women Over 40?
07/21/2025
Rebecca Mashaw
07/21/2025
Gastroenterology
Quiz
What Improves FIT Return Rates?
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
Social Determinants of Health and MASLD/MASH
07/18/2025
Rebecca Mashaw
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several...
07/18/2025
Gastroenterology
Quiz
MASLD in 2050
07/18/2025
Rebecca Mashaw
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of...
07/18/2025
Gastroenterology
Quiz
What Predicts Adherence to mt-sDNA Screening?
07/16/2025
Riya Gandhi, MA
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive...
07/16/2025
Gastroenterology

News

FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Review
Colonoscopy Associated With Lower Colorectal Cancer Risk in Adults Aged 40–49 Years
06/03/2026
Jessica Garlewicz
Investigators observed a lower cumulative incidence of CRC among individuals who underwent colonoscopy across both age groups studied.
Investigators observed a lower cumulative incidence of CRC among individuals who underwent colonoscopy across both age groups studied.
Investigators observed a lower...
06/03/2026
Gastroenterology
Research Insights
Early-Onset Colorectal Cancer Survivors Report Persistent Sexual Health Challenges
05/27/2026
Rebecca Mashaw
A new study adds to growing evidence that sexual and reproductive health issues are common yet frequently overlooked among younger colorectal cancer survivors.
A new study adds to growing evidence that sexual and reproductive health issues are common yet frequently overlooked among younger colorectal cancer survivors.
A new study adds to growing...
05/27/2026
Gastroenterology
Research Review
Synchronous Colon Cancer Not Associated With Worse Survival in Stage I–III Disease
05/27/2026
Jessica Garlewicz
The findings provide reassurance regarding prognosis in patients presenting with multiple primary tumors.
The findings provide reassurance regarding prognosis in patients presenting with multiple primary tumors.
The findings provide reassurance...
05/27/2026
Gastroenterology
News
Lifetime Alcohol Intake Linked to Colorectal Cancer Risk
02/11/2026
Jessica Garlewicz
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key...
02/11/2026
Gastroenterology
Emerging Therapies
EC Plus FOLFIRI Improves Response Rates in First-Line BRAF V600E–Mutant Metastatic Colorectal Cancer
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
Analysis Challenges NordICC Trial Conclusions on CRC Screening and Mortality
09/05/2025
Rebecca Mashaw
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the...
09/05/2025
Gastroenterology
Research Highlights
Cumulative Social Risk Linked to Poorer Survival in Stage III Colorectal Cancer
09/05/2025
Rebecca Mashaw
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
09/05/2025
Gastroenterology
News
Racial Disparities Persist in Colorectal Cancer Outcomes
08/12/2025
Rebecca Mashaw
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in...
08/12/2025
Gastroenterology
News
Over 20 Years of Colorectal Cancer Disparities Reveal Racial and Regional Gaps in US Mortality
08/08/2025
Riya Gandhi, MA
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in...
08/08/2025
Gastroenterology
News
Vonoprazan-Tetracycline Dual Therapy Shows Noninferior H. pylori Eradication
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
Updated Guideline Recommends Selective Antibiotic Use for Outpatient Diverticulitis Management
09/08/2026
Jessica Garlewicz
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline...
09/08/2026
Gastroenterology
News
Low-Dose Gluten Exposure Triggers Immune Activation in Treated Celiac Disease Despite Minimal Symptoms
09/08/2026
Jessica Garlewicz
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten...
09/08/2026
Gastroenterology
News
Combined H. pylori and FIT Screening Found Cost-Effective for Long-Term Cancer Prevention
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
News
Celiac Disease Associated With Nearly 3-Fold Higher Risk of Solid Organ Transplantation
09/08/2026
Jessica Garlewicz
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease...
09/08/2026
Gastroenterology
News
Refined Fibrosis Screening Criteria Reduce Eligible Population, Improve Detection of Advanced Liver Disease
09/08/2026
Jessica Garlewicz
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening...
09/08/2026
Gastroenterology
News
Menopause May Help Explain Age-Related Fibrosis Risk in Women With MASLD
09/08/2026
Jessica Garlewicz
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate...
09/08/2026
Gastroenterology
FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Insights
IBS-C Microbiome Signatures Offer Insights Into Parkinson’s-Related Constipation
06/09/2026
Rebecca Mashaw
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
Gastroenterology

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