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H pylori

Featured Article

News
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
Conference Coverage
10/27/2025
Rebecca Mashaw
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at...
10/27/2025
Gastroenterology
News
09/18/2025
Jessica Garlewicz
The dual mechanism of action and resistance profile of rifasutenizol mark it as a promising agent in the evolving landscape of H. pylori treatment.
The dual mechanism of action and resistance profile of rifasutenizol mark it as a promising agent in the evolving landscape of H. pylori treatment.
The dual mechanism of action and...
09/18/2025
Gastroenterology
News
07/24/2025
Rebecca Mashaw
Inconsistencies in reimbursement coverage, diagnostic tools available contribute to accessibility inequities for H pylori surveillance.
Inconsistencies in reimbursement coverage, diagnostic tools available contribute to accessibility inequities for H pylori surveillance.
Inconsistencies in reimbursement...
07/24/2025
Gastroenterology
News
07/24/2025
Rebecca Mashaw
Researchers noted that clinicians should consider patients’ histories of antibiotic use when treating H pylori.
Researchers noted that clinicians should consider patients’ histories of antibiotic use when treating H pylori.
Researchers noted that...
07/24/2025
Gastroenterology
05/06/2025
Riya Gandhi, MA
New data show that tailoring antibiotic doses by body weight significantly improves H. pylori eradication in obese individuals, challenging the effectiveness of current fixed-dose regimens.
New data show that tailoring antibiotic doses by body weight significantly improves H. pylori eradication in obese individuals, challenging the effectiveness of current fixed-dose regimens.
New data show that tailoring...
05/06/2025
Gastroenterology
News
10/18/2024
Jessica Garlewicz
Upper gastrointestinal (GI) mucosal damage was associated with elevated risk of developing Parkinson's disease.
Upper gastrointestinal (GI) mucosal damage was associated with elevated risk of developing Parkinson's disease.
Upper gastrointestinal (GI)...
10/18/2024
Gastroenterology
News
10/18/2024
Jessica Garlewicz
Vonoprazan offers an effective alternative treatment to intravenous proton pump inhibitors for prevention of rebleeding among patients with high-risk peptic ulcers, researchers found.
Vonoprazan offers an effective alternative treatment to intravenous proton pump inhibitors for prevention of rebleeding among patients with high-risk peptic ulcers, researchers found.
Vonoprazan offers an effective...
10/18/2024
Gastroenterology
News
03/12/2024
Jolynn Tumolo
Investigators find Helicobacter pylori can alter the gut microbiome—and may drive development of colonic tumors.
Investigators find Helicobacter pylori can alter the gut microbiome—and may drive development of colonic tumors.
Investigators find Helicobacter...
03/12/2024
Gastroenterology
Gut Check logo
Podcast
11/24/2023
William D. Chey, MD; Brian E. Lacy, PhD, MD
In this first of a two-part podcast on Helicobacter pylori, Drs Brian Lacy and William Chey discuss the prevalence of H pylori infection and how to best diagnose the condition.
In this first of a two-part podcast on Helicobacter pylori, Drs Brian Lacy and William Chey discuss the prevalence of H pylori infection and how to best diagnose the condition.
In this first of a two-part...
11/24/2023
Gastroenterology

News

News
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
Conference Coverage
10/27/2025
Rebecca Mashaw
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at...
10/27/2025
Gastroenterology
News
07/24/2025
Rebecca Mashaw
Inconsistencies in reimbursement coverage, diagnostic tools available contribute to accessibility inequities for H pylori surveillance.
Inconsistencies in reimbursement coverage, diagnostic tools available contribute to accessibility inequities for H pylori surveillance.
Inconsistencies in reimbursement...
07/24/2025
Gastroenterology
News
07/24/2025
Rebecca Mashaw
Researchers noted that clinicians should consider patients’ histories of antibiotic use when treating H pylori.
Researchers noted that clinicians should consider patients’ histories of antibiotic use when treating H pylori.
Researchers noted that...
07/24/2025
Gastroenterology
News
10/18/2024
Jessica Garlewicz
Upper gastrointestinal (GI) mucosal damage was associated with elevated risk of developing Parkinson's disease.
Upper gastrointestinal (GI) mucosal damage was associated with elevated risk of developing Parkinson's disease.
Upper gastrointestinal (GI)...
10/18/2024
Gastroenterology
News
10/18/2024
Jessica Garlewicz
Vonoprazan offers an effective alternative treatment to intravenous proton pump inhibitors for prevention of rebleeding among patients with high-risk peptic ulcers, researchers found.
Vonoprazan offers an effective alternative treatment to intravenous proton pump inhibitors for prevention of rebleeding among patients with high-risk peptic ulcers, researchers found.
Vonoprazan offers an effective...
10/18/2024
Gastroenterology
News
03/12/2024
Jolynn Tumolo
Investigators find Helicobacter pylori can alter the gut microbiome—and may drive development of colonic tumors.
Investigators find Helicobacter pylori can alter the gut microbiome—and may drive development of colonic tumors.
Investigators find Helicobacter...
03/12/2024
Gastroenterology
News
10/19/2023
Rebecca Mashaw
A new meta-analysis indicates that Helicobacter pylori infection could reduce overall survival among patients receiving immunotherapy for cancer.
A new meta-analysis indicates that Helicobacter pylori infection could reduce overall survival among patients receiving immunotherapy for cancer.
A new meta-analysis indicates...
10/19/2023
Gastroenterology
News
10/10/2023
Rebecca Mashaw
Meta-analysis shows comparability to 3-drug regimens but more evidence is needed.
Meta-analysis shows comparability to 3-drug regimens but more evidence is needed.
Meta-analysis shows...
10/10/2023
Gastroenterology
News
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate...
09/08/2026
Gastroenterology
FDA Approval
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Highlights
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Insights
06/09/2026
Rebecca Mashaw
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
Gastroenterology

Interactive Features

Quiz
08/07/2025
Rebecca Mashaw
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Quiz
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of...
07/18/2025
Gastroenterology

Podcasts

Gut Check logo
Podcast
11/24/2023
William D. Chey, MD; Brian E. Lacy, PhD, MD
In this first of a two-part podcast on Helicobacter pylori, Drs Brian Lacy and William Chey discuss the prevalence of H pylori infection and how to best diagnose the condition.
In this first of a two-part podcast on Helicobacter pylori, Drs Brian Lacy and William Chey discuss the prevalence of H pylori infection and how to best diagnose the condition.
In this first of a two-part...
11/24/2023
Gastroenterology
Gut Check logo
Podcast
07/25/2023
In part 2 of their podcast on Helicobacter pylori, Drs William Chey and Brian Lacy talk about the risks of untreated disease and the various types of treatment available.
In part 2 of their podcast on Helicobacter pylori, Drs William Chey and Brian Lacy talk about the risks of untreated disease and the various types of treatment available.
In part 2 of their podcast on...
07/25/2023
Gastroenterology
Headshot
Podcast
11/18/2021
Discover the importance of acid suppression in H. pylori treatment with hosts Dr Michael Vaezi, professor of medicine at Vanderbilt University Medical Center and Dr David Peura, professor emeritus at the University of Virginia School of...
Discover the importance of acid suppression in H. pylori treatment with hosts Dr Michael Vaezi, professor of medicine at Vanderbilt University Medical Center and Dr David Peura, professor emeritus at the University of Virginia School of...
Discover the importance of acid...
11/18/2021
Gastroenterology
Gut Check logo
Expert Insights
08/19/2026
Brian E. Lacy, PhD, MD; Hans Törnblom, MD
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised...
08/19/2026
Gastroenterology
Gut Check logo
Expert Insights
07/30/2026
Brian E. Lacy, PhD, MD; Benjamin Lebwohl
Dr Brian Lacy hosts celiac disease expert Dr Benjamin Lebwohl to explain the prevalence of the disease, the complexities of accurate diagnosis, and the importance of not relying on symptoms alone.
Dr Brian Lacy hosts celiac disease expert Dr Benjamin Lebwohl to explain the prevalence of the disease, the complexities of accurate diagnosis, and the importance of not relying on symptoms alone.
Dr Brian Lacy hosts celiac...
07/30/2026
Gastroenterology
Robert Gish
Expert Insights
07/15/2026
Robert Gish, MD
Dr Gish discusses the recent approval of bulevirtide for the treatment of hepatitis D, and the importance of screening and monitoring patients with hepatitis B for hepatitis D to enable effective treatment.
Dr Gish discusses the recent approval of bulevirtide for the treatment of hepatitis D, and the importance of screening and monitoring patients with hepatitis B for hepatitis D to enable effective treatment.
Dr Gish discusses the recent...
07/15/2026
Gastroenterology
Gut Check logo
Expert Insights
06/29/2026
Brian E. Lacy, PhD, MD; Philip Okafor, MD
Dr Brian Lacy hosts Dr Philip Okafor for a discussion about health disparities in gastroenterology, including defining health disparities, health equality, and health equity, the populations most affected by disparities, and some potential...
Dr Brian Lacy hosts Dr Philip Okafor for a discussion about health disparities in gastroenterology, including defining health disparities, health equality, and health equity, the populations most affected by disparities, and some potential...
Dr Brian Lacy hosts Dr Philip...
06/29/2026
Gastroenterology
Gut Check logo
Expert Insights
06/19/2026
Brian E. Lacy, PhD, MD; Jacqueline Squire, MD
Drs Jacqueline Squire and Brian Lacy review the challenges of accurately diagnosing mast cell activation syndrome, how it affects the gastrointestinal and other organ systems, and how best to treatment this relatively rare and often...
Drs Jacqueline Squire and Brian Lacy review the challenges of accurately diagnosing mast cell activation syndrome, how it affects the gastrointestinal and other organ systems, and how best to treatment this relatively rare and often...
Drs Jacqueline Squire and Brian...
06/19/2026
Gastroenterology
Gut Check logo
Expert Insights
06/11/2026
Brian E. Lacy, PhD, MD; Andree Koop, MD
In the latest Gut Check podcast, Drs. Brian Lacy and Andree Koop talk about noncardiac chest pain, a common condition that often send patients to emergency departments or primary care and from there to the care of gastroenterologists.
In the latest Gut Check podcast, Drs. Brian Lacy and Andree Koop talk about noncardiac chest pain, a common condition that often send patients to emergency departments or primary care and from there to the care of gastroenterologists.
In the latest Gut Check podcast,...
06/11/2026
Gastroenterology
Gut Check logo
Expert Insights
03/16/2026
Brian E. Lacy, PhD, MD; Darren Brenner, MD
In this episode of Gut Check, host Brian Lacy, MD, and guest Dr Darren Brenner discuss the common symptoms of gas, distension, and bloating--what distinguishes each from the others, possible causes, and how to treat these prevalent...
In this episode of Gut Check, host Brian Lacy, MD, and guest Dr Darren Brenner discuss the common symptoms of gas, distension, and bloating--what distinguishes each from the others, possible causes, and how to treat these prevalent...
In this episode of Gut Check,...
03/16/2026
Gastroenterology
Gut Check logo
Integrative Therapy
01/25/2026
Brian E. Lacy, PhD, MD; Jami Kinnucan, MD
Dr Brian Lacy hosts Dr Jami Kinnucan to discuss the pros and cons of using cannabis to treat some symptoms of gastrointestinal diseases.
Dr Brian Lacy hosts Dr Jami Kinnucan to discuss the pros and cons of using cannabis to treat some symptoms of gastrointestinal diseases.
Dr Brian Lacy hosts Dr Jami...
01/25/2026
Gastroenterology
Gut Check logo
Podcast
12/23/2025
Brian E. Lacy, PhD, MD
In this Gut Check podcast, Dr Brian Lacy hosts Maria Vazquez-Roque, MD, to discuss how fecal microbiota transplantation can be administered in the treatment of C difficile infection and potentially other colonic diseases.
In this Gut Check podcast, Dr Brian Lacy hosts Maria Vazquez-Roque, MD, to discuss how fecal microbiota transplantation can be administered in the treatment of C difficile infection and potentially other colonic diseases.
In this Gut Check podcast, Dr...
12/23/2025
Gastroenterology
Gut Check logo
Podcast
09/23/2025
Brian E. Lacy, PhD, MD
Dr Vivek Kumbari and Dr Brian Lacy discuss the evolution of third-space endoscopy and how it has enabled quicker, simpler and safer procedures throughout the gastrointestinal tract, as well as the potential future of endoscopy as primarily a...
Dr Vivek Kumbari and Dr Brian Lacy discuss the evolution of third-space endoscopy and how it has enabled quicker, simpler and safer procedures throughout the gastrointestinal tract, as well as the potential future of endoscopy as primarily a...
Dr Vivek Kumbari and Dr Brian...
09/23/2025
Gastroenterology