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Hepatology

Featured Article

Research Review
Earlier MASLD Onset Associated With Higher Long-Term Risk of Type 2 Diabetes
09/08/2026
Jessica Garlewicz
Delaying the onset of metabolic dysfunction-associated steatotic liver disease among young adults may reduce their risk of developing type 2 diabetes, new research indicates.
Delaying the onset of metabolic dysfunction-associated steatotic liver disease among young adults may reduce their risk of developing type 2 diabetes, new research indicates.
Delaying the onset of metabolic...
09/08/2026
Gastroenterology
Research Insights
U.S. Dietary Guideline Changes May Conflict With Liver Health Findings
07/16/2026
Rebecca Mashaw
An analysis of just under 11,000 US adults suggest that dietary recommendations for liver health may benefit from greater emphasis on specific food sources rather than total nutrient intake alone.
An analysis of just under 11,000 US adults suggest that dietary recommendations for liver health may benefit from greater emphasis on specific food sources rather than total nutrient intake alone.
An analysis of just under 11,000...
07/16/2026
Gastroenterology
Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
FDA Approval
FDA Approves Bulevirtide for Hepatitis D Treatment
06/01/2026
Rebecca Mashaw
The approval provides the first FDA-approved treatment option specifically indicated for chronic HDV infection, addressing a substantial unmet medical need in hepatology.
The approval provides the first FDA-approved treatment option specifically indicated for chronic HDV infection, addressing a substantial unmet medical need in hepatology.
The approval provides the first...
06/01/2026
Gastroenterology
RESEARCH INSIGHTS
Rising MASLD Prevalence in Younger Adults Linked to Increased Mortality Risk
05/15/2026
Jessica Garlewicz
Importantly, MASLD was linked to increased all-cause mortality in young adults, driven primarily by cardiovascular and metabolic causes.
Importantly, MASLD was linked to increased all-cause mortality in young adults, driven primarily by cardiovascular and metabolic causes.
Importantly, MASLD was linked to...
05/15/2026
Gastroenterology
Research Highlights
Sleeve Gastrectomy Linked to Lower Hepatic Complications Than Gastric Bypass in MASLD
05/07/2026
Jessica Garlewicz
The incidence of hepatocellular carcinoma remained low and did not differ significantly between procedures; rates of liver transplantation were comparable across groups.
The incidence of hepatocellular carcinoma remained low and did not differ significantly between procedures; rates of liver transplantation were comparable across groups.
The incidence of hepatocellular...
05/07/2026
Gastroenterology
Research Summary
MASLD in Pregnancy Rising Rapidly, Linked to Increased Maternal Morbidity
05/07/2026
Jessica Garlewicz
The authors reported that MASLD showed a “nearly threefold rise over the study period” and was “independently associated with significantly higher morbidity.”
The authors reported that MASLD showed a “nearly threefold rise over the study period” and was “independently associated with significantly higher morbidity.”
The authors reported that MASLD...
05/07/2026
Gastroenterology
Research Review
High Persistence and Favorable Safety Observed With Resmetirom in Real-World MASH Cohort
05/06/2026
Rebecca Mashaw
Authors of research presented at Digestive Disease Week concluded that their findings support the “long-term durability, safety, and consistent NIT response of resmetirom in clinical practice.”
Authors of research presented at Digestive Disease Week concluded that their findings support the “long-term durability, safety, and consistent NIT response of resmetirom in clinical practice.”
Authors of research presented at...
05/06/2026
Gastroenterology
Research Review
Tiered MASLD Screening Strategy More Accurate but Misses Significant Fibrosis, Study Finds
05/06/2026
Jessica Garlewicz
The tiered strategy resulted in fewer hepatology referrals (5%) compared with the VCTE-first approach (15%), reflecting more conservative resource use.
The tiered strategy resulted in fewer hepatology referrals (5%) compared with the VCTE-first approach (15%), reflecting more conservative resource use.
The tiered strategy resulted in...
05/06/2026
Gastroenterology
Research Highlights
MAPI Offers New Biomarker in Screening for MetALD and ALD
04/23/2026
Jessica Garlewicz
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index...
04/23/2026
Gastroenterology
FDA Alert
FDA Approves Linerixibat for Pruritis in PBC
03/20/2026
Rebecca Mashaw
The US Food and Drug Administration (FDA) on March 19 approved linerixibat for the treatment of cholestatic pruritus in adult patients with PBC. The ileal bile acid transporter (IBAT) inhibitor reduces multiple drivers of chronic itch, which...
The US Food and Drug Administration (FDA) on March 19 approved linerixibat for the treatment of cholestatic pruritus in adult patients with PBC. The ileal bile acid transporter (IBAT) inhibitor reduces multiple drivers of chronic itch, which...
The US Food and Drug...
03/20/2026
Gastroenterology

Videos

Video
Kayla Monks, MS, RD, on Nutrition for Patients With Liver Disease
06/14/2024
Kayla Monks, MS, RD
Kayla Monks, MS, RD, discusses nutritional needs and challenges of patients with liver disease, including candidates for transplant, and how to work with patients to achieve the best possible outcomes.
Kayla Monks, MS, RD, discusses nutritional needs and challenges of patients with liver disease, including candidates for transplant, and how to work with patients to achieve the best possible outcomes.
Kayla Monks, MS, RD, discusses...
06/14/2024
Gastroenterology
Videos
Lauren Yang, MD, on Hepatitis B Research
12/01/2020
In this video, Lauren Yang, MD, from Beth Israel Deaconess Medical Center, discusses what learned at the recent American Association for the Study of Liver Diseases annual meeting about research into managing hepatitis B.
In this video, Lauren Yang, MD, from Beth Israel Deaconess Medical Center, discusses what learned at the recent American Association for the Study of Liver Diseases annual meeting about research into managing hepatitis B.
In this video, Lauren Yang, MD,...
12/01/2020
Gastroenterology
Expert Insights
What's Ahead for MASLD and MASH?
10/26/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
The expert roundtable on MASH and MASLD wraps up as Drs Fontana, Abdelmalek, and Arab consider advances in progress and encourage gastroenterologists to make use of the tools available today to risk assess, treat, and monitor their patients...
The expert roundtable on MASH and MASLD wraps up as Drs Fontana, Abdelmalek, and Arab consider advances in progress and encourage gastroenterologists to make use of the tools available today to risk assess, treat, and monitor their patients...
The expert roundtable on MASH...
10/26/2026
Gastroenterology
Expert Insights
Emerging Therapies and Bariatric Treatment for MASLD and MASH
10/26/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
Drs Fontana, Abdelmalek, and Arab discuss new therapeutic options now being developed, as well as the continued role of endobariatics as well as surgery, for the treatment of obese patients with MASLD or MASH.
Drs Fontana, Abdelmalek, and Arab discuss new therapeutic options now being developed, as well as the continued role of endobariatics as well as surgery, for the treatment of obese patients with MASLD or MASH.
Drs Fontana, Abdelmalek, and...
10/26/2026
Gastroenterology
Expert Insights
Diet and Alternative Therapies in MASLD and MASH
10/26/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
Drs Fontana, Arab, and Abdelmalek continue their discussion on the treatment of MASLD and MASH, discussing the importance of dietary therapy and the possible addition of vitamin E for some patients, as well as getting follow-up imaging to...
Drs Fontana, Arab, and Abdelmalek continue their discussion on the treatment of MASLD and MASH, discussing the importance of dietary therapy and the possible addition of vitamin E for some patients, as well as getting follow-up imaging to...
Drs Fontana, Arab, and...
10/26/2026
Gastroenterology
Expert Insights
Treating MASLD and MASH
10/26/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
Our expert roundtable on MASLD and MASH takes a dive into the treatments now approved for MASLD and MASH and how to approach shared decision-making with patients when choosing therapeutics.
Our expert roundtable on MASLD and MASH takes a dive into the treatments now approved for MASLD and MASH and how to approach shared decision-making with patients when choosing therapeutics.
Our expert roundtable on MASLD...
10/26/2026
Gastroenterology
Brian Lacy
Conference Coverage
Brian Lacy, MD, on Bloating and Distension
10/26/2026
Brian E. Lacy, PhD, MD
Dr Lacy discusses how to discern between bloating and distension, identifies the key contributors to these conditions, and goes through the treatment options he presented at the ACG Scientific Meeting.
Dr Lacy discusses how to discern between bloating and distension, identifies the key contributors to these conditions, and goes through the treatment options he presented at the ACG Scientific Meeting.
Dr Lacy discusses how to discern...
10/26/2026
Gastroenterology
Rena Yadlapati
Conference Coverage
Rena Yadlapati, MD, on Differentiating Acid vs Nonacid Reflux
10/26/2026
Rena Yadlapati, MD
Dr Yadlapati review her presentation from the ACG Scientific Meeting on diagnosis of acid reflux vs nonacid reflux and how to approach the treatment and monitoring of these conditions.
Dr Yadlapati review her presentation from the ACG Scientific Meeting on diagnosis of acid reflux vs nonacid reflux and how to approach the treatment and monitoring of these conditions.
Dr Yadlapati review her...
10/26/2026
Gastroenterology
Lin Chang
Conference Coverage
Lin Chang, MD, on What's New in Rome V
10/20/2026
Lin Chang, MD
Dr Chang reviews important changes in the Rome V diagnostic criteria for disorders of gut-brain interaction, which she detailed during her lecture at the American College of Gastroenterology Scientific Meeting in Nashville, October 12-14.
Dr Chang reviews important changes in the Rome V diagnostic criteria for disorders of gut-brain interaction, which she detailed during her lecture at the American College of Gastroenterology Scientific Meeting in Nashville, October 12-14.
Dr Chang reviews important...
10/20/2026
Gastroenterology
Expert Insights
Diagnosis and Monitoring in MASLD/MASH
10/16/2026
Robert Fontana, MD; Manal Abdelmalek, MD; Juan Pablo Arab, MD
Drs Fontana, Abdelmalek, and Arab review potential confounders for liver stiffness tests—from food or alcohol to even a cup of coffee—and the best methods to use for both diagnosis and continued monitoring for patients with MASLD or MASH,...
Drs Fontana, Abdelmalek, and Arab review potential confounders for liver stiffness tests—from food or alcohol to even a cup of coffee—and the best methods to use for both diagnosis and continued monitoring for patients with MASLD or MASH,...
Drs Fontana, Abdelmalek, and...
10/16/2026
Gastroenterology
Expert Insights
Fibrosis and Steatosis in MASLD/MASH
10/16/2026
Robert Fontana, MD; Juan Pablo Arab, MD; Manal Abdelmalek, MD
Our expert panel continues this series on MASLD and MASH, discussing how best to diagnose and quantify fibrosis through FIB-4, VCTE, MRE and other blood and imaging tests.
Our expert panel continues this series on MASLD and MASH, discussing how best to diagnose and quantify fibrosis through FIB-4, VCTE, MRE and other blood and imaging tests.
Our expert panel continues this...
10/16/2026
Gastroenterology
Conference Coverage
Folasade May, MD, on What's Driving Early Onset Colorectal Cancer
10/13/2026
Folasade May, MD, PhD
Dr Fola May of UCLA Health discusses her presentation at the ACG Scientific Meeting on the concerning rise in colorectal cancers among patients under 45 and some of the factors being investigated as possible contributors, from genetics and...
Dr Fola May of UCLA Health discusses her presentation at the ACG Scientific Meeting on the concerning rise in colorectal cancers among patients under 45 and some of the factors being investigated as possible contributors, from genetics and...
Dr Fola May of UCLA Health...
10/13/2026
Gastroenterology

News

Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Highlights
MAPI Offers New Biomarker in Screening for MetALD and ALD
04/23/2026
Jessica Garlewicz
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index...
04/23/2026
Gastroenterology
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
Research Highlights
Persistent MASLD Greatly Increases Diabetes and Cardiovascular Risks, Study Finds
12/15/2025
Rebecca Mashaw
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links...
12/15/2025
Gastroenterology
Research Highlights
Sex-Specific Risks Highlight MASLD Burden Across Women’s Lifespan
12/11/2025
Rebecca Mashaw
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD...
12/11/2025
Gastroenterology
Conference Coverage
Resmetirom Reduces Portal Hypertension Risk and Fibrosis Markers in MASH Cirrhosis at 2 Years
11/04/2025
Jessica Garlewicz
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients...
11/04/2025
Gastroenterology
Conference Coverage
Tirzepatide Bests Semaglutide in Reducing Cardiovascular Events and Mortality in Patients With MASLD/MASH
11/04/2025
Jessica Garlewicz
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was...
11/04/2025
Gastroenterology
Research Highlights
Liquid Biopsy Shows Potential in Cholangiocarcinoma Care
10/09/2025
Rebecca Mashaw
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights...
10/09/2025
Gastroenterology
Research Highlights
Tinegotinib Monotherapy Shows Efficacy Among Patients With Advanced/Metastatic Cholangiocarcinoma
10/01/2025
Stephanie Holland
An ongoing randomized, controlled phase III study will evaluate the clinical efficacy, safety, and pharmacodynamic effect of tinengotinib for refractory/relapsed cholangiocarcinoma.
An ongoing randomized, controlled phase III study will evaluate the clinical efficacy, safety, and pharmacodynamic effect of tinengotinib for refractory/relapsed cholangiocarcinoma.
An ongoing randomized,...
10/01/2025
Gastroenterology
Research Highlights
Incidence of Hepatocellular Carcinoma in MASLD Patients Quantified in Large Meta-Analysis
09/15/2025
Rebecca Mashaw
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight...
09/15/2025
Gastroenterology
News
Vonoprazan-Tetracycline Dual Therapy Shows Noninferior H. pylori Eradication
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
Updated Guideline Recommends Selective Antibiotic Use for Outpatient Diverticulitis Management
09/08/2026
Jessica Garlewicz
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline...
09/08/2026
Gastroenterology
News
Low-Dose Gluten Exposure Triggers Immune Activation in Treated Celiac Disease Despite Minimal Symptoms
09/08/2026
Jessica Garlewicz
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten...
09/08/2026
Gastroenterology
News
Combined H. pylori and FIT Screening Found Cost-Effective for Long-Term Cancer Prevention
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
News
Celiac Disease Associated With Nearly 3-Fold Higher Risk of Solid Organ Transplantation
09/08/2026
Jessica Garlewicz
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease...
09/08/2026
Gastroenterology
News
Refined Fibrosis Screening Criteria Reduce Eligible Population, Improve Detection of Advanced Liver Disease
09/08/2026
Jessica Garlewicz
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening...
09/08/2026
Gastroenterology
News
Menopause May Help Explain Age-Related Fibrosis Risk in Women With MASLD
09/08/2026
Jessica Garlewicz
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate...
09/08/2026
Gastroenterology
FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Insights
IBS-C Microbiome Signatures Offer Insights Into Parkinson’s-Related Constipation
06/09/2026
Rebecca Mashaw
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
Gastroenterology

News

Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Highlights
MAPI Offers New Biomarker in Screening for MetALD and ALD
04/23/2026
Jessica Garlewicz
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index (MAP) proved to be the top-performing model among all commonly used indirect alcohol biomarkers.
MetALD-ALD Prediction Index...
04/23/2026
Gastroenterology
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
Research Highlights
Persistent MASLD Greatly Increases Diabetes and Cardiovascular Risks, Study Finds
12/15/2025
Rebecca Mashaw
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links...
12/15/2025
Gastroenterology
Research Highlights
Sex-Specific Risks Highlight MASLD Burden Across Women’s Lifespan
12/11/2025
Rebecca Mashaw
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD...
12/11/2025
Gastroenterology
Conference Coverage
Resmetirom Reduces Portal Hypertension Risk and Fibrosis Markers in MASH Cirrhosis at 2 Years
11/04/2025
Jessica Garlewicz
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients...
11/04/2025
Gastroenterology
Conference Coverage
Tirzepatide Bests Semaglutide in Reducing Cardiovascular Events and Mortality in Patients With MASLD/MASH
11/04/2025
Jessica Garlewicz
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was...
11/04/2025
Gastroenterology
Research Highlights
Liquid Biopsy Shows Potential in Cholangiocarcinoma Care
10/09/2025
Rebecca Mashaw
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights...
10/09/2025
Gastroenterology
Research Highlights
Tinegotinib Monotherapy Shows Efficacy Among Patients With Advanced/Metastatic Cholangiocarcinoma
10/01/2025
Stephanie Holland
An ongoing randomized, controlled phase III study will evaluate the clinical efficacy, safety, and pharmacodynamic effect of tinengotinib for refractory/relapsed cholangiocarcinoma.
An ongoing randomized, controlled phase III study will evaluate the clinical efficacy, safety, and pharmacodynamic effect of tinengotinib for refractory/relapsed cholangiocarcinoma.
An ongoing randomized,...
10/01/2025
Gastroenterology
Research Highlights
Incidence of Hepatocellular Carcinoma in MASLD Patients Quantified in Large Meta-Analysis
09/15/2025
Rebecca Mashaw
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight...
09/15/2025
Gastroenterology
News
Vonoprazan-Tetracycline Dual Therapy Shows Noninferior H. pylori Eradication
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
Updated Guideline Recommends Selective Antibiotic Use for Outpatient Diverticulitis Management
09/08/2026
Jessica Garlewicz
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline...
09/08/2026
Gastroenterology
News
Low-Dose Gluten Exposure Triggers Immune Activation in Treated Celiac Disease Despite Minimal Symptoms
09/08/2026
Jessica Garlewicz
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten...
09/08/2026
Gastroenterology
News
Combined H. pylori and FIT Screening Found Cost-Effective for Long-Term Cancer Prevention
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
News
Celiac Disease Associated With Nearly 3-Fold Higher Risk of Solid Organ Transplantation
09/08/2026
Jessica Garlewicz
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease...
09/08/2026
Gastroenterology
News
Refined Fibrosis Screening Criteria Reduce Eligible Population, Improve Detection of Advanced Liver Disease
09/08/2026
Jessica Garlewicz
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of US population data with...
A refined fibrosis screening...
09/08/2026
Gastroenterology
News
Menopause May Help Explain Age-Related Fibrosis Risk in Women With MASLD
09/08/2026
Jessica Garlewicz
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate...
09/08/2026
Gastroenterology
FDA Approval
FDA Approves SimpleScreen CRC Blood Test for U.S. Colorectal Cancer Screening
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology
Research Highlights
GLP-1 RAs Linked to Lower Risk of Hepatic Complications in MASLD and T2D
06/11/2026
Jessica Garlewicz
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found that patients with MASLD and type 2 diabetes who were not using GLP-1 RAs had a signficantly higher rate of hepatic complications compared to patients receiving GLP-1 therapy.
A real-world cohort study found...
06/11/2026
Gastroenterology
Research Insights
IBS-C Microbiome Signatures Offer Insights Into Parkinson’s-Related Constipation
06/09/2026
Rebecca Mashaw
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights important similarities and differences between IBS-C and Parkinson’s disease–associated constipation.
New research highlights...
06/09/2026
Gastroenterology

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