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Disorders of Gut-Brain Interaction

Featured Article

Consensus Statement
08/25/2026
Rebecca Mashaw
The Rome Foundation and IOIBD developed consensus recommendations for the identifying and managing IBS-like symptoms among patients with IBD but without uncontrolled inflammation.
The Rome Foundation and IOIBD developed consensus recommendations for the identifying and managing IBS-like symptoms among patients with IBD but without uncontrolled inflammation.
The Rome Foundation and IOIBD...
08/25/2026
Advances in Inflammatory Bowel Disease Network
From Advances in Inflammatory Bowel Disease Network
Gut Check logo
Expert Insights
08/19/2026
Brian E. Lacy, PhD, MD; Hans Törnblom, MD
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised...
08/19/2026
Gastroenterology
Brian Lacy
Expert Insights
05/06/2026
Brian E. Lacy, PhD, MD
Dr Lacy explains some of the key changes in criteria for disorders of gut-brain interaction, including irritable bowel syndrome and abdominal pain/discomfort, found in the recently published ROME V.
Dr Lacy explains some of the key changes in criteria for disorders of gut-brain interaction, including irritable bowel syndrome and abdominal pain/discomfort, found in the recently published ROME V.
Dr Lacy explains some of the key...
05/06/2026
Gastroenterology
Research Highlights
05/04/2026
Rebecca Mashaw
Clinicians should consider both infection-related and treatment-related factors when evaluating IBS risk.
Clinicians should consider both infection-related and treatment-related factors when evaluating IBS risk.
Clinicians should consider both...
05/04/2026
Gastroenterology
Research Highlights
05/04/2026
Rebecca Mashaw
The randomized, placebo-controlled trial evaluated clinical outcomes, quality of life, and microbiome changes in adults meeting Rome IV criteria for irritable bowel syndrome with diarrhea.
The randomized, placebo-controlled trial evaluated clinical outcomes, quality of life, and microbiome changes in adults meeting Rome IV criteria for irritable bowel syndrome with diarrhea.
The randomized,...
05/04/2026
Gastroenterology
Research Highlights
01/15/2026
Rebecca Mashaw
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial...
01/15/2026
Gastroenterology
News
09/18/2025
Jessica Garlewicz
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this...
09/18/2025
Gastroenterology
News
08/28/2025
Riya Gandhi, MA
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general...
08/28/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
News
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology

Insights

Gut Check logo
Expert Insights
08/19/2026
Brian E. Lacy, PhD, MD; Hans Törnblom, MD
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised...
08/19/2026
Gastroenterology
Brian Lacy
Expert Insights
05/06/2026
Brian E. Lacy, PhD, MD
Dr Lacy explains some of the key changes in criteria for disorders of gut-brain interaction, including irritable bowel syndrome and abdominal pain/discomfort, found in the recently published ROME V.
Dr Lacy explains some of the key changes in criteria for disorders of gut-brain interaction, including irritable bowel syndrome and abdominal pain/discomfort, found in the recently published ROME V.
Dr Lacy explains some of the key...
05/06/2026
Gastroenterology
News
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
Gut Check logo
Podcast
04/18/2025
Brian E. Lacy, PhD, MD; Laurie Keefer
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian...
04/18/2025
Gastroenterology
Gut Check logo
Podcast
03/10/2025
Brian E. Lacy, PhD, MD; Dacre Knight, MD
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides...
03/10/2025
Gastroenterology
Bill Chey
Expert Insights
07/30/2024
William D. Chey, MD
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation...
07/30/2024
Gastroenterology
Gut Check logo
Podcast
05/08/2024
Douglas A. Drossman, MD
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas...
05/08/2024
Gastroenterology
Gut Check
Podcast
08/07/2023
William D. Chey, MD; Lin Chang
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal...
08/07/2023
Gastroenterology
gut brain interaction
News
06/02/2023
Priyam Vora
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the...
06/02/2023
Gastroenterology
Emaran Mayer, MD
Conference Coverage
06/01/2023
Priyam Vora
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut...
06/01/2023
Gastroenterology
News
09/08/2026
Jessica Garlewicz
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline dual regimen was noninferior to bismuth quadruple therapy as rescue treatment for Helicobacter pylori infection and was associated with fewer adverse events and better adherence, according to results from a...
A 14-day vonoprazan-tetracycline...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline outlines practical recommendations for the outpatient management of colonic diverticulitis, emphasizing confirmation of diagnosis with computed tomography (CT), selective use of antibiotics, and lifestyle...
A new evidence-based guideline...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten triggered measurable immune activation in adults with treated celiac disease, even when symptoms were absent, according to a randomized, placebo-controlled dose-response trial. The findings suggest that immune...
Very small amounts of gluten...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter pylori stool antigen testing to biennial fecal immunochemical test (FIT) screening may improve long-term health outcomes while remaining economically favorable, according to a cost-effectiveness analysis based on...
Adding one-time Helicobacter...
09/08/2026
Gastroenterology
News
09/08/2026
Jessica Garlewicz
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease (CeD) may face a substantially increased risk of solid organ transplantation, particularly liver transplantation, according to a nationwide population-based cohort study from Sweden. Although celiac disease has...
Patients with celiac disease...
09/08/2026
Gastroenterology
News
09/08/2026
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of U.S. population data...
A refined fibrosis screening strategy substantially reduced the number of adults identified for screening while increasing the likelihood of detecting clinically significant liver fibrosis, according to an analysis of U.S. population data...
A refined fibrosis screening...
09/08/2026
Gastroenterology
News
09/08/2026
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate the association between aging and advanced fibrosis in women with metabolic dysfunction-associated steatotic liver disease (MASLD), according to findings from a causal mediation analysis of the Harris County...
Menopause may partially mediate...
09/08/2026
Gastroenterology
Gut Check logo
Expert Insights
08/19/2026
Brian E. Lacy, PhD, MD; Hans Törnblom, MD
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised criteria for gastroduodenal disorders with host Dr Brian Lacy as part of the overview of new Rome V guide for disorders of gut-brain interaction.
Dr Törnblom reviews the revised...
08/19/2026
Gastroenterology
Gut Check logo
Expert Insights
07/30/2026
Brian E. Lacy, PhD, MD; Benjamin Lebwohl
Dr Brian Lacy hosts celiac disease expert Dr Benjamin Lebwohl to explain the prevalence of the disease, the complexities of accurate diagnosis, and the importance of not relying on symptoms alone.
Dr Brian Lacy hosts celiac disease expert Dr Benjamin Lebwohl to explain the prevalence of the disease, the complexities of accurate diagnosis, and the importance of not relying on symptoms alone.
Dr Brian Lacy hosts celiac...
07/30/2026
Gastroenterology
FDA Approval
07/28/2026
Rebecca Mashaw
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on results of PREEMPT CRC, a prospective clinical validation study that enrolled more than 48,000 asymptomatic, average-risk adults between the ages of 45 and 85.
FDA approval was based on...
07/28/2026
Gastroenterology