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Disorders of Gut-Brain Interaction Topic Center

Featured Article

Research Highlights
01/15/2026
Rebecca Mashaw
Constipation-predominant irritable bowel syndrome (IBS-C) is a common functional gastrointestinal disorder with unclear biological mechanisms. A study published in Frontiers in Microbiology reports distinct alterations in gut microbiota...
Constipation-predominant irritable bowel syndrome (IBS-C) is a common functional gastrointestinal disorder with unclear biological mechanisms. A study published in Frontiers in Microbiology reports distinct alterations in gut microbiota...
Constipation-predominant...
01/15/2026
Gastroenterology
News
09/18/2025
Jessica Garlewicz
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this...
09/18/2025
Gastroenterology
News
08/28/2025
Riya Gandhi, MA
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general...
08/28/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
News
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Gut Check logo
Podcast
04/18/2025
Brian E. Lacy, PhD, MD; Laurie Keefer
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian...
04/18/2025
Gastroenterology
Gut Check logo
Podcast
03/10/2025
Brian E. Lacy, PhD, MD; Dacre Knight, MD
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides...
03/10/2025
Gastroenterology
Bill Chey
Expert Insights
07/30/2024
William D. Chey, MD
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation...
07/30/2024
Gastroenterology
Gut Check logo
Podcast
05/08/2024
Douglas A. Drossman, MD
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas...
05/08/2024
Gastroenterology
doc with stethoscope
Poll
01/09/2024
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal...
01/09/2024
Gastroenterology

Insights

News
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
Gut Check logo
Podcast
04/18/2025
Brian E. Lacy, PhD, MD; Laurie Keefer
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian...
04/18/2025
Gastroenterology
Gut Check logo
Podcast
03/10/2025
Brian E. Lacy, PhD, MD; Dacre Knight, MD
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides...
03/10/2025
Gastroenterology
Bill Chey
Expert Insights
07/30/2024
William D. Chey, MD
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation...
07/30/2024
Gastroenterology
Gut Check logo
Podcast
05/08/2024
Douglas A. Drossman, MD
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas...
05/08/2024
Gastroenterology
Gut Check
Podcast
08/07/2023
William D. Chey, MD; Lin Chang
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal...
08/07/2023
Gastroenterology
gut brain interaction
News
06/02/2023
Priyam Vora
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the...
06/02/2023
Gastroenterology
Emaran Mayer, MD
Conference Coverage
06/01/2023
Priyam Vora
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut...
06/01/2023
Gastroenterology
Keefer 2021
Podcast
05/03/2023
In this podcast, Dr Keefer, from the Icahn School of Medicine at Mt Sinai in New York City, discusses how different types of behavioral therapies can help in the management of disorders of gut-brain interaction, such as irritable bowel...
In this podcast, Dr Keefer, from the Icahn School of Medicine at Mt Sinai in New York City, discusses how different types of behavioral therapies can help in the management of disorders of gut-brain interaction, such as irritable bowel...
In this podcast, Dr Keefer, from...
05/03/2023
Gastroenterology
News
09/12/2022
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the...
09/12/2022
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
In an abstract presented at the ASTRO meeting, investigators indicated that circulating tumor DNA may predict recurrence of rectal cancer following short-course radiation therapy.
In an abstract presented at the ASTRO meeting, investigators indicated that circulating tumor DNA may predict recurrence of rectal cancer following short-course radiation therapy.
In an abstract presented at the...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
01/14/2026
Gastroenterology
Kim Orleck
Clinical Pearls
01/13/2026
Kimberly Orleck, ANP-BC
Kimberly Orleck, ANP-BC, reviews the key points to consider when diagnosing a patient with constipation to determine if the condition is irritable bowel syndrome with predominant constipation.
Kimberly Orleck, ANP-BC, reviews the key points to consider when diagnosing a patient with constipation to determine if the condition is irritable bowel syndrome with predominant constipation.
Kimberly Orleck, ANP-BC, reviews...
01/13/2026
Gastroenterology
Sid Barritt
How I Treat
01/08/2026
A. Sidney Barritt, MD
Dr Barritt discusses how he approaches the treatment of MASLD and MASH, both with medical therapies and lifestyle adaptations.
Dr Barritt discusses how he approaches the treatment of MASLD and MASH, both with medical therapies and lifestyle adaptations.
Dr Barritt discusses how he...
01/08/2026
Gastroenterology
Expert Insights
01/05/2026
In Part 2 of this expert roundtable Drs Afdhal, Bansal, and Younossi discuss how to determine which patients need to be screened for MASLD/MASH, how to conduct screening, and which modalities are best.
In Part 2 of this expert roundtable Drs Afdhal, Bansal, and Younossi discuss how to determine which patients need to be screened for MASLD/MASH, how to conduct screening, and which modalities are best.
In Part 2 of this expert...
01/05/2026
Gastroenterology
Expert Insights
01/02/2026
In part 1 of this multipart series on MASLD and MASH, Drs Nezam Afdhal, Meena Bansal, and Zobair Younossi provide an overview of the growing prevalence of metabolic-associated steatotic liver disease (MASLD) and metabolic-associated...
In part 1 of this multipart series on MASLD and MASH, Drs Nezam Afdhal, Meena Bansal, and Zobair Younossi provide an overview of the growing prevalence of metabolic-associated steatotic liver disease (MASLD) and metabolic-associated...
In part 1 of this multipart...
01/02/2026
Gastroenterology
Gut Check logo
Podcast
12/23/2025
Brian E. Lacy, PhD, MD
In this Gut Check podcast, Dr Brian Lacy hosts Maria Vazquez-Roque, MD, to discuss how fecal microbiota transplantation can be administered in the treatment of C difficile infection and potentially other colonic diseases.
In this Gut Check podcast, Dr Brian Lacy hosts Maria Vazquez-Roque, MD, to discuss how fecal microbiota transplantation can be administered in the treatment of C difficile infection and potentially other colonic diseases.
In this Gut Check podcast, Dr...
12/23/2025
Gastroenterology
Research Highlights
12/15/2025
Rebecca Mashaw
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links...
12/15/2025
Gastroenterology
Research Highlights
12/11/2025
Rebecca Mashaw
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD...
12/11/2025
Gastroenterology