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Chronic Total Occlusion Topic Center Original Contribution

Original Contribution
10/29/2026
Semi Ozturk, MD; Ahmet Seyfeddin Gurbuz, MD; Sule Goktekin, MD; Sevket Gorgulu, MD
The authors analyzed retrograde CTO PCI procedures from a multicenter registry to identify clinical, angiographic, and collateral-pathway factors associated with collateral channel crossing failure and to evaluate their association with...
The authors analyzed retrograde CTO PCI procedures from a multicenter registry to identify clinical, angiographic, and collateral-pathway factors associated with collateral channel crossing failure and to evaluate their association with...
The authors analyzed retrograde...
10/29/2026
Journal of Invasive Cardiology
Original Contribution
10/09/2026
Marios Tsourous, MD; Dimitrios Strepkos, MD; Theodoros Vichos, MD; Michaella Alexandrou, MD; Pedro E.P. Carvalho, MD; Ahmet Akyel, MD; Parth Desai, MD; Ayman Fath, MD; Sophie Macy, BS; James W. Choi, MD; Sevket Gorgulu, MD; Farouc A. Jaffer, MD; Raj Chandwaney, MD; Khaldoon Alaswad, MD; Mir B. Basir, MD; Lorenzo Azzalini, MD, PhD, MSc; Dmitrii Khelimskii, MD; Oleg Krestyaninov, MD; Laura Young, MD; Omer Goktekin, MD; Konstantinos Voudris, MD; Noah N. Williford, MD; Angie S. Lobo, MD; Yader Sandoval, MD; Emmanouil S. Brilakis, MD, PhD
The authors evaluated the clinical characteristics and procedural outcomes of dialysis patients undergoing chronic total occlusion percutaneous coronary intervention in a large, multicenter registry.
The authors evaluated the clinical characteristics and procedural outcomes of dialysis patients undergoing chronic total occlusion percutaneous coronary intervention in a large, multicenter registry.
The authors evaluated the...
10/09/2026
Journal of Invasive Cardiology
Original Contribution
07/23/2026
Madjid Boukantar, MD; Oueies Labidi, MD; Patrick Zamora, MD; Romain Gallet, MD, PhD; Tony Truong, MD; Nicolas Lellouche, MD, PhD; Nadia Oubaya, MD; Pierre Andre Natella, MD; Philippe Le Corvoisier, MD; Paul Mathieu Chiaroni, MD; Emmanuel Teiger, MD, PhD
The SXS-CTO trial was designed to compare the incidence of stent malapposition between self-expanding drug-eluting stents (DES) (STENTYS Xposition S [STENTYS S.A]) and balloon-expandable DES in patients undergoing chronic total occlusion...
The SXS-CTO trial was designed to compare the incidence of stent malapposition between self-expanding drug-eluting stents (DES) (STENTYS Xposition S [STENTYS S.A]) and balloon-expandable DES in patients undergoing chronic total occlusion...
The SXS-CTO trial was designed...
07/23/2026
Journal of Invasive Cardiology
Review
05/12/2026
Semih Ceylan; Deniz Mutlu, MD; Eleni Kladou, MD; Nick Williford, MD; Sandeep Jalli, MD; Ahmed Al-Ogaili, MD; Masahisa Yamane, MD; Khaldoon Alaswad, MD; Allison Hall, MD; Rhian Davies, DO; James W. Choi, MD; Andrea Gagnor, MD; Roberto Garbo, MD; Omer Goktekin, MD; Sevket Gorgulu, MD; Jaikirshan J. Khatri, MD; William Nicholson, MD; Stéphane Rinfret, MD; Wissam Jaber, MD; Mohaned Egred, MD; Anastasios Milkas, MD, PhD; Niccolò Ciardetti, MD; Carlo Di Mario, MD, PhD; Kambis Mashayekhi, MD, PhD; Alexandre Avran, MD; Gregor Leibundgut, MD; Yiannis S. Chatzizisis, MD, PhD; Gerald S. Werner, MD, PhD; Claudiu Ungureanu, MD; Yader Sandoval, MD; Emmanouil S. Brilakis, MD, PhD
This review provides a summary of the published literature in CTO PCI between September 2023 and April 2025, categorized by procedural outcomes, techniques, complications, and ongoing studies.
This review provides a summary of the published literature in CTO PCI between September 2023 and April 2025, categorized by procedural outcomes, techniques, complications, and ongoing studies.
This review provides a summary...
05/12/2026
Journal of Invasive Cardiology
Original Contribution
05/17/2025
Dimitrios Strepkos, MD; Athanasios Rempakos, MD; Michaella Alexandrou, MD; Deniz Mutlu, MD; Pedro E.P. Carvalho, MD; Ozgur Selim Ser, MD; Khaldoon Alaswad, MD; Mir Babar Basir, DO; Dmitrii Khelimskii, MD; Oleg Krestyaninov, MD; Jaikirshan J. Khatri, MD; Laura D. Young, MD; Omer Goktekin, MD; Paul Poommipanit, MD; Farouc A. Jaffer, MD, PhD; Sevket Gorgulu, MD; Ahmed M. ElGuindy, MD; Nidal Abi Rafeh, MD; Olga C. Mastrodemos, BA; Bavana V. Rangan, BDS, MPH; Sandeep Jalli, DO; Konstantinos Voudris, MD, PhD; Yader Sandoval, MD; M. Nicholas Burke, MD; Emmanouil S. Brilakis, MD, PhD
The impact of contrast type in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) remains controversial. The authors sought to evaluate the impact of contrast medium selection on patients undergoing CTO PCI.
The impact of contrast type in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) remains controversial. The authors sought to evaluate the impact of contrast medium selection on patients undergoing CTO PCI.
The impact of contrast type in...
05/17/2025
Journal of Invasive Cardiology
Review
05/13/2025
Athanasios Rempakos, MD; Pranathi Pilla, BSc; Michaella Alexandrou, MD; Deniz Mutlu, MD; Dimitrios Strepkos, MD; Pedro E.P. Carvalho, MD; Ozgur Selim Ser, MD; Ali Bahbah, MD; Amit Amin, MD; Anand Prasad, MD; Lorenzo Azzalini, MD, PhD; Luiz F. Ybarra, MD; Olga C. Mastrodemos, BA; Bavana V. Rangan, BDS, MPH; Ahmed Al-Ogaili, MD; Sandeep Jalli, DO; M. Nicholas Burke, MD; Yader Sandoval, MD; Emmanouil S. Brilakis, MD, PhD
The authors review the latest AI-based innovations in the diagnosis of chronic total occlusions (CTO) and in determining the probability of success of CTO PCI.
The authors review the latest AI-based innovations in the diagnosis of chronic total occlusions (CTO) and in determining the probability of success of CTO PCI.
The authors review the latest...
05/13/2025
Journal of Invasive Cardiology
Original Contribution
03/04/2025
Soichiro Ebisawa, MD, PhD; Etsuo Tsuchikane, MD, PhD; Koichi Kishi, MD; Yoshiaki Ito, MD, PhD; Hisayuki Okada, MD, PhD; Satoru Sumitsuji, MD; Yuji Oikawa, MD; Ryohei Yoshikawa, MD; Hiroyuki Tanaka, MD
This study aimed to compare the strategies and initial success rates of chronic total occlusion-percutaneous coronary intervention in patients with and without prior coronary artery bypass graft.
This study aimed to compare the strategies and initial success rates of chronic total occlusion-percutaneous coronary intervention in patients with and without prior coronary artery bypass graft.
This study aimed to compare the...
03/04/2025
Journal of Invasive Cardiology
Original Contribution
01/13/2025
Deniz Mutlu, MD; Dimitrios Strepkos, MD; Pedro E.P. Carvalho, MD; Michaella Alexandrou, MD; Ahmed Al-Ogaili, MD; Sandeep Jalli, MD; Khaldoon Alaswad, MD; Farouc A. Jaffer, MD; Rhian Davies, DO, MS; Paul Poommipanit, MD; Jarrod Frizzell, MD; Basem Elbarouni, MD; Jaikirshan J. Khatri, MD; Sevket Gorgulu, MD; Omer Goktekin, MD; Ramazan Ozdemir, MD; Mahmut Uluganyan, MD; Ahmed ElGuindy, MD; Yasser Sadek, MD; Yousif Ahmad, BMedSci, BMBS, PhD; Mir B. Basir, MD; Leah Raj, MD; Luiz Ybarra, MD, PhD; Bilal Murad, MD; Bavana V. Rangan, BDS, MPH; Olga C. Mastrodemos, BA; Lorenzo Azzalini, MD, PhD, MSc; Yader Sandoval, MD; M. Nicholas Burke, MD; Emmanouil S. Brilakis, MD, PhD
The authors examined the frequency and outcomes of Ostial Flash balloon use in aorto-ostial chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in a multicenter contemporary CTO-PCI registry.
The authors examined the frequency and outcomes of Ostial Flash balloon use in aorto-ostial chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in a multicenter contemporary CTO-PCI registry.
The authors examined the...
01/13/2025
Journal of Invasive Cardiology
Original Contribution
12/30/2024
Maksymilian P. Opolski, MD, PhD; Antoni Zyśk, MD; Wojciech Skorupski, MD, PhD; Artur Dębski, MD, PhD; Adam Witkowski, MD, PhD
The authors performed a 2-arm randomized controlled trial to compare the time, efficacy and safety outcomes between an antegrade wiring (AW) strategy using a first-choice intermediate tip-load polymer-jacketed guidewire vs an AW strategy...
The authors performed a 2-arm randomized controlled trial to compare the time, efficacy and safety outcomes between an antegrade wiring (AW) strategy using a first-choice intermediate tip-load polymer-jacketed guidewire vs an AW strategy...
The authors performed a 2-arm...
12/30/2024
Journal of Invasive Cardiology
Original Contribution
09/30/2024
Michaella Alexandrou, MD; Athanasios Rempakos, MD; Deniz Mutlu, MD; Dimitrios Strepkos, MD; Pedro E.P. Carvalho, MD; Ahmed Al-Ogaili, MD; Anastasios Milkas, MD; Ioannis Tsiafoutis, MD; Khaldoon Alaswad, MD; Mir Babar Basir, DO; Rhian Davies, DO, MS; Farouc A. Jaffer, MD, PhD; William Nicholson, MD; Lorenzo Azzalini, MD, PhD, MSc; Sevket Gorgulu, MD; Jaikirshan J. Khatri, MD; Sripal Bangalore, MD, MHA; Bavana V. Rangan, BDS, MPH; Olga C. Mastrodemos, BA; M. Nicholas Burke, MD; Yader Sandoval, MD; Emmanouil S. Brilakis, MD, PhD
The authors compared the predictions for successful antegrade wiring of chronic total occlusion lesions made by interventional cardiologists with those from a machine learning model.
The authors compared the predictions for successful antegrade wiring of chronic total occlusion lesions made by interventional cardiologists with those from a machine learning model.
The authors compared the...
09/30/2024
Journal of Invasive Cardiology