Traumatic brain injury (TBI) was linked with a 2.6-fold higher risk of a subsequent amyotrophic lateral sclerosis (ALS) diagnosis than in the general population, according to a study published in JAMA Network Open.
Traumatic brain injury (TBI) was linked with a 2.6-fold higher risk of a subsequent amyotrophic lateral sclerosis (ALS) diagnosis than in the general population, according to a study published in JAMA Network Open.
A case-control study has identified a potential link between use of certain psychiatric medications and the risk and progression of amyotrophic lateral sclerosis (ALS). Findings were published in JAMA Network Open.
A case-control study has identified a potential link between use of certain psychiatric medications and the risk and progression of amyotrophic lateral sclerosis (ALS). Findings were published in JAMA Network Open.
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
More than a third of patients with amyotrophic lateral sclerosis (ALS) had neuropathological signs of frontotemporal dementia, according to study results published in Brain.
More than a third of patients with amyotrophic lateral sclerosis (ALS) had neuropathological signs of frontotemporal dementia, according to study results published in Brain.
The US Food and Drug Administration (FDA) declined to grant accelerated approval of the experimental drug CNM-Au8 for the treatment of amyotrophic lateral sclerosis (ALS).
The US Food and Drug Administration (FDA) declined to grant accelerated approval of the experimental drug CNM-Au8 for the treatment of amyotrophic lateral sclerosis (ALS).
A novel scoring system may help predict a person’s risk of developing amyotrophic lateral sclerosis (ALS) by weighing the combined effects of common genetic variants, according to a study published online in Neurology Genetics.
“This...
A novel scoring system may help predict a person’s risk of developing amyotrophic lateral sclerosis (ALS) by weighing the combined effects of common genetic variants, according to a study published online in Neurology Genetics.
“This...
A newly discovered potential biomarker may aid in the diagnosis and treatment of sporadic amyotrophic lateral sclerosis (ALS), according to a research letter published in the Journal of Neurology, Neurosurgery, and Psychiatry.
A newly discovered potential biomarker may aid in the diagnosis and treatment of sporadic amyotrophic lateral sclerosis (ALS), according to a research letter published in the Journal of Neurology, Neurosurgery, and Psychiatry.
Patients with amyotrophic lateral sclerosis (ALS) exhibit different gaze patterns when visually scanning human facial expressions compared to healthy controls, according to new study findings.
Patients with amyotrophic lateral sclerosis (ALS) exhibit different gaze patterns when visually scanning human facial expressions compared to healthy controls, according to new study findings.
Members of the committee agreed 9-0 that a demonstrated reduction in plasma neurofilament light chain (NfL) concentration in patients with SOD1-ALS is reasonably likely to predict clinical benefit.
Members of the committee agreed 9-0 that a demonstrated reduction in plasma neurofilament light chain (NfL) concentration in patients with SOD1-ALS is reasonably likely to predict clinical benefit.
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A case-control study has identified a potential link between use of certain psychiatric medications and the risk and progression of amyotrophic lateral sclerosis (ALS). Findings were published in JAMA Network Open.
A case-control study has identified a potential link between use of certain psychiatric medications and the risk and progression of amyotrophic lateral sclerosis (ALS). Findings were published in JAMA Network Open.
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
More than a third of patients with amyotrophic lateral sclerosis (ALS) had neuropathological signs of frontotemporal dementia, according to study results published in Brain.
More than a third of patients with amyotrophic lateral sclerosis (ALS) had neuropathological signs of frontotemporal dementia, according to study results published in Brain.
The US Food and Drug Administration (FDA) declined to grant accelerated approval of the experimental drug CNM-Au8 for the treatment of amyotrophic lateral sclerosis (ALS).
The US Food and Drug Administration (FDA) declined to grant accelerated approval of the experimental drug CNM-Au8 for the treatment of amyotrophic lateral sclerosis (ALS).
A novel scoring system may help predict a person’s risk of developing amyotrophic lateral sclerosis (ALS) by weighing the combined effects of common genetic variants, according to a study published online in Neurology Genetics.
“This...
A novel scoring system may help predict a person’s risk of developing amyotrophic lateral sclerosis (ALS) by weighing the combined effects of common genetic variants, according to a study published online in Neurology Genetics.
“This...
A newly discovered potential biomarker may aid in the diagnosis and treatment of sporadic amyotrophic lateral sclerosis (ALS), according to a research letter published in the Journal of Neurology, Neurosurgery, and Psychiatry.
A newly discovered potential biomarker may aid in the diagnosis and treatment of sporadic amyotrophic lateral sclerosis (ALS), according to a research letter published in the Journal of Neurology, Neurosurgery, and Psychiatry.
Patients with amyotrophic lateral sclerosis (ALS) exhibit different gaze patterns when visually scanning human facial expressions compared to healthy controls, according to new study findings.
Patients with amyotrophic lateral sclerosis (ALS) exhibit different gaze patterns when visually scanning human facial expressions compared to healthy controls, according to new study findings.
Members of the committee agreed 9-0 that a demonstrated reduction in plasma neurofilament light chain (NfL) concentration in patients with SOD1-ALS is reasonably likely to predict clinical benefit.
Members of the committee agreed 9-0 that a demonstrated reduction in plasma neurofilament light chain (NfL) concentration in patients with SOD1-ALS is reasonably likely to predict clinical benefit.
The US Food and Drug Administration (FDA) recently granted Orphan Drug Designation to RAG-17, a novel short interfering RNA (siRNA) modality for the treatment of patients with amyotrophic lateral sclerosis (ALS), biopharmaceutical company...
The US Food and Drug Administration (FDA) recently granted Orphan Drug Designation to RAG-17, a novel short interfering RNA (siRNA) modality for the treatment of patients with amyotrophic lateral sclerosis (ALS), biopharmaceutical company...
Delirium documented within 30 days of hospitalization was associated with a significantly higher risk of mild cognitive impairment and dementia, according to longitudinal cohort findings.
Delirium documented within 30 days of hospitalization was associated with a significantly higher risk of mild cognitive impairment and dementia, according to longitudinal cohort findings.
Several vascular risk factors, including smoking, hypertension, diabetes and prior stroke, were associated with LOE in older adults, according to pooled analysis findings.
Several vascular risk factors, including smoking, hypertension, diabetes and prior stroke, were associated with LOE in older adults, according to pooled analysis findings.
A meta-analysis of 38,418 participants across 18 countries or territories estimated 11.4 million new dementia cases globally in 2023, with annual incidence projected to reach 24.7 million by 2050.
A meta-analysis of 38,418 participants across 18 countries or territories estimated 11.4 million new dementia cases globally in 2023, with annual incidence projected to reach 24.7 million by 2050.
Treatment with ocrelizumab for up to 10 years was associated with sustained relapse control and minimal disability accrual in patients with relapsing MS, according to phase 3 findings.
Treatment with ocrelizumab for up to 10 years was associated with sustained relapse control and minimal disability accrual in patients with relapsing MS, according to phase 3 findings.
A nationwide cohort study found that prior use of P2Y12 inhibitors, either alone or combined with aspirin, was associated with more severe presentation and worse hospital outcomes in patients with spontaneous ICH.
A nationwide cohort study found that prior use of P2Y12 inhibitors, either alone or combined with aspirin, was associated with more severe presentation and worse hospital outcomes in patients with spontaneous ICH.
Plasma p-tau217/Aβ42 ratio accurately detected amyloid-PET positivity in veterans without traumatic brain injury (TBI), but accuracy declined significantly in those with prior TBI.
Plasma p-tau217/Aβ42 ratio accurately detected amyloid-PET positivity in veterans without traumatic brain injury (TBI), but accuracy declined significantly in those with prior TBI.
A longitudinal study reports that parity may modify the relationship between Alzheimer disease (AD) pathology and brain aging in cognitively unimpaired postmenopausal women.
A longitudinal study reports that parity may modify the relationship between Alzheimer disease (AD) pathology and brain aging in cognitively unimpaired postmenopausal women.
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
A multicenter randomized clinical trial found that reperfusion-guided systolic blood pressure (BP) management after successful endovascular therapy improved 90-day functional outcomes compared with guideline-recommended care.
A multicenter randomized clinical trial found that reperfusion-guided systolic blood pressure (BP) management after successful endovascular therapy improved 90-day functional outcomes compared with guideline-recommended care.
SKY-0515, an investigational oral RNA splicing modifier, reduced mutant huntingtin (mHTT) protein levels in blood by up to 69% and PMS1 mRNA by up to 26% in a phase 1/2 Huntington’s disease (HD) trial.
SKY-0515, an investigational oral RNA splicing modifier, reduced mutant huntingtin (mHTT) protein levels in blood by up to 69% and PMS1 mRNA by up to 26% in a phase 1/2 Huntington’s disease (HD) trial.
