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Migraine Topic Center

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News
Fremanezumab Reduces Migraine Days, Depressive Symptoms in Patients with Migraine and Comorbid MDD
06/02/2025
Jolynn Tumolo
Compared with placebo, fremanezumab significantly reduced both monthly migraine days and depressive symptoms in patients with migraine and moderate to severe comorbid MDD, according to a study published in JAMA Neurology.
Compared with placebo, fremanezumab significantly reduced both monthly migraine days and depressive symptoms in patients with migraine and moderate to severe comorbid MDD, according to a study published in JAMA Neurology.
Compared with placebo,...
06/02/2025
Psych Congress Network
man experiencing headache
News
Combined Strategies Best for Medication-Overuse Headache, Network Meta-Analysis Finds
05/22/2025
Jolynn Tumolo
Combination therapies were most effective for reducing monthly headache days in patients with medication-overuse headache, also known as rebound headache, according to a network meta-analysis.
Combination therapies were most effective for reducing monthly headache days in patients with medication-overuse headache, also known as rebound headache, according to a network meta-analysis.
Combination therapies were most...
05/22/2025
Neurology
illustration of a laptop screen displaying a test
Quiz
Effective Treatment Approaches for Menstrual Migraine
05/12/2025
Maria Mantas
Brush up on your knowledge of treatment approaches for menstrual migraines!
Brush up on your knowledge of treatment approaches for menstrual migraines!
Brush up on your knowledge of...
05/12/2025
Neurology
Newer Migraine Drugs Offer No Clinically Important Advantage, ACP Guideline Reports
News
Newer Migraine Drugs Offer No Clinically Important Advantage, ACP Guideline Reports
02/14/2025
Jolynn Tumolo
A new clinical guideline from the American College of Physicians (ACP) advises monotherapy for episodic migraine prevention in nonpregnant adults in the outpatient setting. The guideline, published in the Annals of Internal Medicine, provides...
A new clinical guideline from the American College of Physicians (ACP) advises monotherapy for episodic migraine prevention in nonpregnant adults in the outpatient setting. The guideline, published in the Annals of Internal Medicine, provides...
A new clinical guideline from...
02/14/2025
Neurology
A new mom sits on the couch holding her infant, and her forehead
News
Gestational Hypertension, Preeclampsia, and Eclampsia Associated With Greater Incidence of Future Neurological Disorders
02/13/2025
Brionna Mendoza
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of...
02/13/2025
Neurology
A wrench with the word 'pain' on it holds the head of a wooden figurine in a vice grip
Quiz
Acute or Preventative Migraine Treatment?
01/28/2025
Test your knowledge of practice guidelines with this quiz!
Test your knowledge of practice guidelines with this quiz!
Test your knowledge of practice...
01/28/2025
Neurology
A woman holds her forehead in pain with a migraine
News
Analysis Finds Early Improvement With Migraine Prevention Drug
01/13/2025
Jolynn Tumolo
The migraine prevention drug atogepant may work immediately in patients with episodic and chronic migraine, according to a study published in Neurology.
The migraine prevention drug atogepant may work immediately in patients with episodic and chronic migraine, according to a study published in Neurology.
The migraine prevention drug...
01/13/2025
Neurology
A woman holds her forehead in pain with a migraine
News
Single-Dose Infusion Reduces Migraine Frequency in Phase 2 Trial
09/13/2024
Jolynn Tumolo
Intravenous Lu AG09222 reduced migraine frequency over 4 weeks in patients who had failed to find relief with previous treatments, according to a phase 2 trial published in the New England Journal of Medicine.
Intravenous Lu AG09222 reduced migraine frequency over 4 weeks in patients who had failed to find relief with previous treatments, according to a phase 2 trial published in the New England Journal of Medicine.
Intravenous Lu AG09222 reduced...
09/13/2024
Neurology
A woman holds her forehead in pain with a migraine
News
No Link Found Between Migraine and Parkinson Disease, Contrary to Previous Findings
08/28/2024
Brionna Mendoza
A new cohort study involving female participants found no link between migraine and later Parkinson disease (PD) development. Findings from the study were published in Neurology.
A new cohort study involving female participants found no link between migraine and later Parkinson disease (PD) development. Findings from the study were published in Neurology.
A new cohort study involving...
08/28/2024
Neurology
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
News
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
08/08/2024
Evi Arthur
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive...
08/08/2024
Neurology

Migraine CME Series

News

brain graphic
News
Fremanezumab Reduces Migraine Days, Depressive Symptoms in Patients with Migraine and Comorbid MDD
06/02/2025
Jolynn Tumolo
Compared with placebo, fremanezumab significantly reduced both monthly migraine days and depressive symptoms in patients with migraine and moderate to severe comorbid MDD, according to a study published in JAMA Neurology.
Compared with placebo, fremanezumab significantly reduced both monthly migraine days and depressive symptoms in patients with migraine and moderate to severe comorbid MDD, according to a study published in JAMA Neurology.
Compared with placebo,...
06/02/2025
Psych Congress Network
man experiencing headache
News
Combined Strategies Best for Medication-Overuse Headache, Network Meta-Analysis Finds
05/22/2025
Jolynn Tumolo
Combination therapies were most effective for reducing monthly headache days in patients with medication-overuse headache, also known as rebound headache, according to a network meta-analysis.
Combination therapies were most effective for reducing monthly headache days in patients with medication-overuse headache, also known as rebound headache, according to a network meta-analysis.
Combination therapies were most...
05/22/2025
Neurology
Newer Migraine Drugs Offer No Clinically Important Advantage, ACP Guideline Reports
News
Newer Migraine Drugs Offer No Clinically Important Advantage, ACP Guideline Reports
02/14/2025
Jolynn Tumolo
A new clinical guideline from the American College of Physicians (ACP) advises monotherapy for episodic migraine prevention in nonpregnant adults in the outpatient setting. The guideline, published in the Annals of Internal Medicine, provides...
A new clinical guideline from the American College of Physicians (ACP) advises monotherapy for episodic migraine prevention in nonpregnant adults in the outpatient setting. The guideline, published in the Annals of Internal Medicine, provides...
A new clinical guideline from...
02/14/2025
Neurology
A new mom sits on the couch holding her infant, and her forehead
News
Gestational Hypertension, Preeclampsia, and Eclampsia Associated With Greater Incidence of Future Neurological Disorders
02/13/2025
Brionna Mendoza
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of...
02/13/2025
Neurology
A woman holds her forehead in pain with a migraine
News
Analysis Finds Early Improvement With Migraine Prevention Drug
01/13/2025
Jolynn Tumolo
The migraine prevention drug atogepant may work immediately in patients with episodic and chronic migraine, according to a study published in Neurology.
The migraine prevention drug atogepant may work immediately in patients with episodic and chronic migraine, according to a study published in Neurology.
The migraine prevention drug...
01/13/2025
Neurology
A woman holds her forehead in pain with a migraine
News
Single-Dose Infusion Reduces Migraine Frequency in Phase 2 Trial
09/13/2024
Jolynn Tumolo
Intravenous Lu AG09222 reduced migraine frequency over 4 weeks in patients who had failed to find relief with previous treatments, according to a phase 2 trial published in the New England Journal of Medicine.
Intravenous Lu AG09222 reduced migraine frequency over 4 weeks in patients who had failed to find relief with previous treatments, according to a phase 2 trial published in the New England Journal of Medicine.
Intravenous Lu AG09222 reduced...
09/13/2024
Neurology
A woman holds her forehead in pain with a migraine
News
No Link Found Between Migraine and Parkinson Disease, Contrary to Previous Findings
08/28/2024
Brionna Mendoza
A new cohort study involving female participants found no link between migraine and later Parkinson disease (PD) development. Findings from the study were published in Neurology.
A new cohort study involving female participants found no link between migraine and later Parkinson disease (PD) development. Findings from the study were published in Neurology.
A new cohort study involving...
08/28/2024
Neurology
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
News
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
08/08/2024
Evi Arthur
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive...
08/08/2024
Neurology
a hand breaks a wooden human figurine in half
News
Atogepant Reduces Migraine Days in Patients With Pain Medication Overuse
07/18/2024
Jolynn Tumolo
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related...
07/18/2024
Neurology
A woman suffers from a migraine
News
Patients With Episodic Migraine 6 Time More Likely to Reduce Monthly Migraine Days With Erenumab
04/17/2024
Brionna Mendoza
In episodic migraine, patients treated with erenumab were 6 times more likely to achieve 50% or greater reduction in monthly migraine days, compared to ongoing treatment with nonspecific oral migraine preventive medications (OMPMs). Results...
In episodic migraine, patients treated with erenumab were 6 times more likely to achieve 50% or greater reduction in monthly migraine days, compared to ongoing treatment with nonspecific oral migraine preventive medications (OMPMs). Results...
In episodic migraine, patients...
04/17/2024
Neurology
FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
brain scan
News
Moderate to Severe TBI Linked With Development of Malignant Brain Tumors
09/08/2025
Jolynn Tumolo
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe...
09/08/2025
Neurology
A woman lies in bed with her mouth open snoring sleep apnea
News
New AASM Patient-Reported Outcome Tool Valid for Monitoring Sleep Apnea
09/08/2025
Jolynn Tumolo
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool...
09/08/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
An illustration of a brain with a puzzle piece missing, surrounded by doctors with elderly patients
News
In Early Trial, Ambroxol Shows Promise for Parkinson Disease Dementia
09/02/2025
Jolynn Tumolo
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for...
09/02/2025
Neurology
A head in profile with cogs coming out of it against an orange background
News
Less Than a Third of Patients With Focal Epilepsy Become Seizure-Free on First ASM
08/26/2025
Jolynn Tumolo
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly...
08/26/2025
Neurology
A teddy bear against a blue background wearing a mask and stethoscope.
News
Phase 2 Trial Finds Risdiplam Effective and Safe in Newborns With SMA
08/21/2025
Jolynn Tumolo
Infants with presymptomatic spinal muscular atrophy (SMA) treated with risdiplam as early as 16 days of age had better functional and survival outcomes at 12 and 24 months compared with untreated infants with SMA.
Infants with presymptomatic spinal muscular atrophy (SMA) treated with risdiplam as early as 16 days of age had better functional and survival outcomes at 12 and 24 months compared with untreated infants with SMA.
Infants with presymptomatic...
08/21/2025
Neurology
brain scans
News
Early Intravenous Immunoglobulins May Improve Outcomes in Anti-IgLON5 Disease
08/18/2025
Jolynn Tumolo
Starting intravenous immunoglobulins within the first year of anti-IgLON5 disease onset was associated with better outcomes and fewer deaths over follow-up, according to study results published in JAMA Neurology.
Starting intravenous immunoglobulins within the first year of anti-IgLON5 disease onset was associated with better outcomes and fewer deaths over follow-up, according to study results published in JAMA Neurology.
Starting intravenous...
08/18/2025
Neurology
A woman lies in bed awake due to insomnia
News
Cannabinoids Produce Worse Sleep Outcomes in Small Pilot Study
08/15/2025
Brionna Mendoza
A single dose of tetrahydrocannabinol/cannabidiol (THC/CBD) resulted in worse sleep for study participants with insomnia.
A single dose of tetrahydrocannabinol/cannabidiol (THC/CBD) resulted in worse sleep for study participants with insomnia.
A single dose of...
08/15/2025
Neurology
child sitting at a desk
News
Oseltamivir Reduces Risk of Serious Neuropsychiatric Events in Children During Influenza Episodes
08/13/2025
Maria Mantas
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was...
08/13/2025
Neurology

Alzheimer's Disease CME Series

Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology

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