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Alzheimer Disease Topic Center

Recent News and Updates

FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
Alzheimer Disease Drugs Show Double the Impact in Long-Term Extension Results
08/05/2025
Jolynn Tumolo
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer...
08/05/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Multiple Sclerosis May Increase Risk for Alzheimer Disease
07/30/2025
Brionna Mendoza
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may...
07/30/2025
Neurology
Alzheimer Disease & Cognitive Disorders Symposium
Conference Coverage
Alzheimer's Disease and Cognitive Disorders Symposium: Agenda Highlights
07/17/2025
Marwan Sabbagh, MD
Learn more about the Alzheimer's Disease and Cognitive Disorder Symposium with this video from Co-Chair Marwan Sabbagh, MD, FAAN, FANA.
Learn more about the Alzheimer's Disease and Cognitive Disorder Symposium with this video from Co-Chair Marwan Sabbagh, MD, FAAN, FANA.
Learn more about the Alzheimer's...
07/17/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
AS01-Adjuvanted Shingles and RSV Vaccines Linked to Lower Dementia Risk
07/14/2025
Brionna Mendoza
A new retrospective cohort study of over 436,000 individuals suggests that AS01-adjuvanted vaccines are independently associated with a reduced risk of dementia diagnosis over 18 months, relative to flu vaccination.
A new retrospective cohort study of over 436,000 individuals suggests that AS01-adjuvanted vaccines are independently associated with a reduced risk of dementia diagnosis over 18 months, relative to flu vaccination.
A new retrospective cohort study...
07/14/2025
Neurology
A brain puzzle against an orange background with one piece missing
News
Dementia Incidence Among Veterans Varies Across US Regions
06/24/2025
Jolynn Tumolo
The incidence of dementia among older veterans varies significantly across US regions, with the Southeast, Northwest, and Rocky Mountains boasting the highest rates.
The incidence of dementia among older veterans varies significantly across US regions, with the Southeast, Northwest, and Rocky Mountains boasting the highest rates.
The incidence of dementia among...
06/24/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Up to 44% of Dementia Diagnoses Attributable to Modifiable Vascular Risk Factors
06/16/2025
Jolynn Tumolo
Maintaining optimal vascular health throughout life may substantially reduce the risk of dementia before age 80 years, suggest study findings published in JAMA Neurology.
Maintaining optimal vascular health throughout life may substantially reduce the risk of dementia before age 80 years, suggest study findings published in JAMA Neurology.
Maintaining optimal vascular...
06/16/2025
Neurology
FDA approval stamp
News
FDA Clears First Blood Test to Help Diagnose Alzheimer Disease
05/19/2025
Meagan Thistle
The FDA has approved the Lumipulse G pTau217/β-Amyloid 1-42 Plasma Ratio test, the first blood-based diagnostic tool intended to aid in evaluating Alzheimer disease (AD) pathology.
The FDA has approved the Lumipulse G pTau217/β-Amyloid 1-42 Plasma Ratio test, the first blood-based diagnostic tool intended to aid in evaluating Alzheimer disease (AD) pathology.
The FDA has approved the...
05/19/2025
Psych Congress Network
From Psych Congress Network
Laboratory medical diagnostics
News
Cerebrospinal Fluid AD Biomarkers Also Common in Other Dementias
05/14/2025
Jolynn Tumolo
A cross-sectional study of patients with a dementia diagnosis found that while core cerebrospinal fluid biomarkers for Alzheimer disease (AD) were most common in AD, they were also frequent in other dementias.
A cross-sectional study of patients with a dementia diagnosis found that while core cerebrospinal fluid biomarkers for Alzheimer disease (AD) were most common in AD, they were also frequent in other dementias.
A cross-sectional study of...
05/14/2025
Neurology
illustration of a test
Quiz
Which factors increase the risk of late-onset epilepsy (LOE) in people with cognitive decline?
04/23/2025
Maria Mantas
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors...
04/23/2025
Neurology

Quizzes

illustration of a test
Quiz
Which factors increase the risk of late-onset epilepsy (LOE) in people with cognitive decline?
04/23/2025
Maria Mantas
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors...
04/23/2025
Neurology
quiz
Quiz
Percentage of Patients With Major or Mild Frontotemporal NCD Found With Alzheimer Disease Pathology at Autopsy
07/11/2024
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients...
07/11/2024
Psych Congress Network
Pop quiz!
Quiz
Delirium Episodes and Incident Dementia Diagnosis
04/23/2024
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to...
04/23/2024
Neurology
Quiz
How did pet ownership affect cognitive decline in older adults?
02/09/2024
How did pets affect cognitive decline?
How did pets affect cognitive decline?
How did pets affect cognitive...
02/09/2024
Neurology
Which factors were associated with young-onset dementia risk?
Quiz
Which factors were associated with young-onset dementia risk?
01/23/2024
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic...
01/23/2024
Neurology
How many years of PPI use increased dementia risk?
Quiz
How many years of PPI use increased dementia risk?
09/28/2023
Pop quiz!
Pop quiz!
Pop quiz!
09/28/2023
Neurology
By how much does Alzheimer Disease increase epilepsy risk?
Quiz
Alzheimer disease increases epilepsy risk by what percent?
07/21/2023
Test your knowlege!
Test your knowlege!
Test your knowlege!
07/21/2023
Neurology
Did the MIND or Mediterranean diets affect Alzheimer Disease pathology?
Quiz
Do MIND or Mediterranean diets affect Alzheimer Disease pathology?
07/05/2023
Do you remember this study?
Do you remember this study?
Do you remember this study?
07/05/2023
Neurology
An illustrated picture shows two cartoon doctors, one holding up a magnifying glass to a cartoon brain.
Quiz
Which investigational oral agent reduces Alzheimer disease biomarkers?
03/29/2023
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge...
03/29/2023
Neurology
An illustration of a pencil marking answers on a quiz sheet.
Expert Insights Quiz
Which aspect of sleep best predicts worsening cognitive function?
02/17/2023
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge...
02/17/2023
Neurology
Pop quiz written on a blackboard with white chalk
Expert Insights Quiz
Mimics in Excessive Daytime Sleepiness
09/10/2025
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
09/10/2025
Neurology
quiz
Quiz
Early DOAC Initiation in AF-Related Ischemic Stroke
08/27/2025
Maria Mantas
Do you remember the details of this meta-analysis?
Do you remember the details of this meta-analysis?
Do you remember the details of...
08/27/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
Vyalev Contraindications
07/29/2025
Brionna Mendoza
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
07/29/2025
Neurology
four people ponder a question with question marks over their head
Quiz
Dopaminergic Therapy in Early Parkinson Disease
07/10/2025
Test your guideline knowledge with this quick quiz!
Test your guideline knowledge with this quick quiz!
Test your guideline knowledge...
07/10/2025
Neurology
Three illustrated faces, one sad, one neutral, one happy, with a human hand picking up the happy face
Quiz
Head Positioning Before Thrombectomy
06/25/2025
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
06/25/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
Epidural Steroids for Spinal Stenosis
06/12/2025
Brionna Mendoza
Test your clinical guideline knowledge with this quick quiz!
Test your clinical guideline knowledge with this quick quiz!
Test your clinical guideline...
06/12/2025
Neurology
illustration of a laptop screen displaying a test
Quiz
Effective Treatment Approaches for Menstrual Migraine
05/12/2025
Maria Mantas
Brush up on your knowledge of treatment approaches for menstrual migraines!
Brush up on your knowledge of treatment approaches for menstrual migraines!
Brush up on your knowledge of...
05/12/2025
Neurology
illustration of a test
Quiz
Which factors increase the risk of late-onset epilepsy (LOE) in people with cognitive decline?
04/23/2025
Maria Mantas
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors...
04/23/2025
Neurology
Take the Quiz!
Quiz
Parkinson Disease Diagnosis: Test Your Knowledge of Clinical Criteria
03/07/2025
Meagan Thistle
Think you know the key clinical features required to diagnose Parkinson disease? Put your knowledge of MDS criteria to the test!
Think you know the key clinical features required to diagnose Parkinson disease? Put your knowledge of MDS criteria to the test!
Think you know the key clinical...
03/07/2025
Neurology
A wrench with the word 'pain' on it holds the head of a wooden figurine in a vice grip
Quiz
Acute or Preventative Migraine Treatment?
01/28/2025
Test your knowledge of practice guidelines with this quiz!
Test your knowledge of practice guidelines with this quiz!
Test your knowledge of practice...
01/28/2025
Neurology

News

FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
Alzheimer Disease Drugs Show Double the Impact in Long-Term Extension Results
08/05/2025
Jolynn Tumolo
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer...
08/05/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Multiple Sclerosis May Increase Risk for Alzheimer Disease
07/30/2025
Brionna Mendoza
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may...
07/30/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
AS01-Adjuvanted Shingles and RSV Vaccines Linked to Lower Dementia Risk
07/14/2025
Brionna Mendoza
A new retrospective cohort study of over 436,000 individuals suggests that AS01-adjuvanted vaccines are independently associated with a reduced risk of dementia diagnosis over 18 months, relative to flu vaccination.
A new retrospective cohort study of over 436,000 individuals suggests that AS01-adjuvanted vaccines are independently associated with a reduced risk of dementia diagnosis over 18 months, relative to flu vaccination.
A new retrospective cohort study...
07/14/2025
Neurology
A brain puzzle against an orange background with one piece missing
News
Dementia Incidence Among Veterans Varies Across US Regions
06/24/2025
Jolynn Tumolo
The incidence of dementia among older veterans varies significantly across US regions, with the Southeast, Northwest, and Rocky Mountains boasting the highest rates.
The incidence of dementia among older veterans varies significantly across US regions, with the Southeast, Northwest, and Rocky Mountains boasting the highest rates.
The incidence of dementia among...
06/24/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Up to 44% of Dementia Diagnoses Attributable to Modifiable Vascular Risk Factors
06/16/2025
Jolynn Tumolo
Maintaining optimal vascular health throughout life may substantially reduce the risk of dementia before age 80 years, suggest study findings published in JAMA Neurology.
Maintaining optimal vascular health throughout life may substantially reduce the risk of dementia before age 80 years, suggest study findings published in JAMA Neurology.
Maintaining optimal vascular...
06/16/2025
Neurology
FDA approval stamp
News
FDA Clears First Blood Test to Help Diagnose Alzheimer Disease
05/19/2025
Meagan Thistle
The FDA has approved the Lumipulse G pTau217/β-Amyloid 1-42 Plasma Ratio test, the first blood-based diagnostic tool intended to aid in evaluating Alzheimer disease (AD) pathology.
The FDA has approved the Lumipulse G pTau217/β-Amyloid 1-42 Plasma Ratio test, the first blood-based diagnostic tool intended to aid in evaluating Alzheimer disease (AD) pathology.
The FDA has approved the...
05/19/2025
Psych Congress Network
Laboratory medical diagnostics
News
Cerebrospinal Fluid AD Biomarkers Also Common in Other Dementias
05/14/2025
Jolynn Tumolo
A cross-sectional study of patients with a dementia diagnosis found that while core cerebrospinal fluid biomarkers for Alzheimer disease (AD) were most common in AD, they were also frequent in other dementias.
A cross-sectional study of patients with a dementia diagnosis found that while core cerebrospinal fluid biomarkers for Alzheimer disease (AD) were most common in AD, they were also frequent in other dementias.
A cross-sectional study of...
05/14/2025
Neurology
older woman on bed rest
News
Olfactory Deficits Signal Mortality Risk From Neurodegenerative Causes in Older Adults
04/14/2025
Jolynn Tumolo
Each additional incorrect answer by older adults on an odor identification test increased all-cause mortality risk by 6% over 6 years, according to a recent study.
Each additional incorrect answer by older adults on an odor identification test increased all-cause mortality risk by 6% over 6 years, according to a recent study.
Each additional incorrect answer...
04/14/2025
Neurology
FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
brain scan
News
Moderate to Severe TBI Linked With Development of Malignant Brain Tumors
09/08/2025
Jolynn Tumolo
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe...
09/08/2025
Neurology
A woman lies in bed with her mouth open snoring sleep apnea
News
New AASM Patient-Reported Outcome Tool Valid for Monitoring Sleep Apnea
09/08/2025
Jolynn Tumolo
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool...
09/08/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
An illustration of a brain with a puzzle piece missing, surrounded by doctors with elderly patients
News
In Early Trial, Ambroxol Shows Promise for Parkinson Disease Dementia
09/02/2025
Jolynn Tumolo
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for...
09/02/2025
Neurology
A head in profile with cogs coming out of it against an orange background
News
Less Than a Third of Patients With Focal Epilepsy Become Seizure-Free on First ASM
08/26/2025
Jolynn Tumolo
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly...
08/26/2025
Neurology
A teddy bear against a blue background wearing a mask and stethoscope.
News
Phase 2 Trial Finds Risdiplam Effective and Safe in Newborns With SMA
08/21/2025
Jolynn Tumolo
Infants with presymptomatic spinal muscular atrophy (SMA) treated with risdiplam as early as 16 days of age had better functional and survival outcomes at 12 and 24 months compared with untreated infants with SMA.
Infants with presymptomatic spinal muscular atrophy (SMA) treated with risdiplam as early as 16 days of age had better functional and survival outcomes at 12 and 24 months compared with untreated infants with SMA.
Infants with presymptomatic...
08/21/2025
Neurology
brain scans
News
Early Intravenous Immunoglobulins May Improve Outcomes in Anti-IgLON5 Disease
08/18/2025
Jolynn Tumolo
Starting intravenous immunoglobulins within the first year of anti-IgLON5 disease onset was associated with better outcomes and fewer deaths over follow-up, according to study results published in JAMA Neurology.
Starting intravenous immunoglobulins within the first year of anti-IgLON5 disease onset was associated with better outcomes and fewer deaths over follow-up, according to study results published in JAMA Neurology.
Starting intravenous...
08/18/2025
Neurology
A woman lies in bed awake due to insomnia
News
Cannabinoids Produce Worse Sleep Outcomes in Small Pilot Study
08/15/2025
Brionna Mendoza
A single dose of tetrahydrocannabinol/cannabidiol (THC/CBD) resulted in worse sleep for study participants with insomnia.
A single dose of tetrahydrocannabinol/cannabidiol (THC/CBD) resulted in worse sleep for study participants with insomnia.
A single dose of...
08/15/2025
Neurology
child sitting at a desk
News
Oseltamivir Reduces Risk of Serious Neuropsychiatric Events in Children During Influenza Episodes
08/13/2025
Maria Mantas
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was...
08/13/2025
Neurology

Migraine CME Series

News

FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
Alzheimer Disease Drugs Show Double the Impact in Long-Term Extension Results
08/05/2025
Jolynn Tumolo
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer...
08/05/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Multiple Sclerosis May Increase Risk for Alzheimer Disease
07/30/2025
Brionna Mendoza
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may...
07/30/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
AS01-Adjuvanted Shingles and RSV Vaccines Linked to Lower Dementia Risk
07/14/2025
Brionna Mendoza
A new retrospective cohort study of over 436,000 individuals suggests that AS01-adjuvanted vaccines are independently associated with a reduced risk of dementia diagnosis over 18 months, relative to flu vaccination.
A new retrospective cohort study of over 436,000 individuals suggests that AS01-adjuvanted vaccines are independently associated with a reduced risk of dementia diagnosis over 18 months, relative to flu vaccination.
A new retrospective cohort study...
07/14/2025
Neurology
A brain puzzle against an orange background with one piece missing
News
Dementia Incidence Among Veterans Varies Across US Regions
06/24/2025
Jolynn Tumolo
The incidence of dementia among older veterans varies significantly across US regions, with the Southeast, Northwest, and Rocky Mountains boasting the highest rates.
The incidence of dementia among older veterans varies significantly across US regions, with the Southeast, Northwest, and Rocky Mountains boasting the highest rates.
The incidence of dementia among...
06/24/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Up to 44% of Dementia Diagnoses Attributable to Modifiable Vascular Risk Factors
06/16/2025
Jolynn Tumolo
Maintaining optimal vascular health throughout life may substantially reduce the risk of dementia before age 80 years, suggest study findings published in JAMA Neurology.
Maintaining optimal vascular health throughout life may substantially reduce the risk of dementia before age 80 years, suggest study findings published in JAMA Neurology.
Maintaining optimal vascular...
06/16/2025
Neurology
FDA approval stamp
News
FDA Clears First Blood Test to Help Diagnose Alzheimer Disease
05/19/2025
Meagan Thistle
The FDA has approved the Lumipulse G pTau217/β-Amyloid 1-42 Plasma Ratio test, the first blood-based diagnostic tool intended to aid in evaluating Alzheimer disease (AD) pathology.
The FDA has approved the Lumipulse G pTau217/β-Amyloid 1-42 Plasma Ratio test, the first blood-based diagnostic tool intended to aid in evaluating Alzheimer disease (AD) pathology.
The FDA has approved the...
05/19/2025
Psych Congress Network
Laboratory medical diagnostics
News
Cerebrospinal Fluid AD Biomarkers Also Common in Other Dementias
05/14/2025
Jolynn Tumolo
A cross-sectional study of patients with a dementia diagnosis found that while core cerebrospinal fluid biomarkers for Alzheimer disease (AD) were most common in AD, they were also frequent in other dementias.
A cross-sectional study of patients with a dementia diagnosis found that while core cerebrospinal fluid biomarkers for Alzheimer disease (AD) were most common in AD, they were also frequent in other dementias.
A cross-sectional study of...
05/14/2025
Neurology
older woman on bed rest
News
Olfactory Deficits Signal Mortality Risk From Neurodegenerative Causes in Older Adults
04/14/2025
Jolynn Tumolo
Each additional incorrect answer by older adults on an odor identification test increased all-cause mortality risk by 6% over 6 years, according to a recent study.
Each additional incorrect answer by older adults on an odor identification test increased all-cause mortality risk by 6% over 6 years, according to a recent study.
Each additional incorrect answer...
04/14/2025
Neurology
FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
brain scan
News
Moderate to Severe TBI Linked With Development of Malignant Brain Tumors
09/08/2025
Jolynn Tumolo
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe...
09/08/2025
Neurology
A woman lies in bed with her mouth open snoring sleep apnea
News
New AASM Patient-Reported Outcome Tool Valid for Monitoring Sleep Apnea
09/08/2025
Jolynn Tumolo
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool...
09/08/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
An illustration of a brain with a puzzle piece missing, surrounded by doctors with elderly patients
News
In Early Trial, Ambroxol Shows Promise for Parkinson Disease Dementia
09/02/2025
Jolynn Tumolo
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for...
09/02/2025
Neurology
A head in profile with cogs coming out of it against an orange background
News
Less Than a Third of Patients With Focal Epilepsy Become Seizure-Free on First ASM
08/26/2025
Jolynn Tumolo
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly...
08/26/2025
Neurology
A teddy bear against a blue background wearing a mask and stethoscope.
News
Phase 2 Trial Finds Risdiplam Effective and Safe in Newborns With SMA
08/21/2025
Jolynn Tumolo
Infants with presymptomatic spinal muscular atrophy (SMA) treated with risdiplam as early as 16 days of age had better functional and survival outcomes at 12 and 24 months compared with untreated infants with SMA.
Infants with presymptomatic spinal muscular atrophy (SMA) treated with risdiplam as early as 16 days of age had better functional and survival outcomes at 12 and 24 months compared with untreated infants with SMA.
Infants with presymptomatic...
08/21/2025
Neurology
brain scans
News
Early Intravenous Immunoglobulins May Improve Outcomes in Anti-IgLON5 Disease
08/18/2025
Jolynn Tumolo
Starting intravenous immunoglobulins within the first year of anti-IgLON5 disease onset was associated with better outcomes and fewer deaths over follow-up, according to study results published in JAMA Neurology.
Starting intravenous immunoglobulins within the first year of anti-IgLON5 disease onset was associated with better outcomes and fewer deaths over follow-up, according to study results published in JAMA Neurology.
Starting intravenous...
08/18/2025
Neurology
A woman lies in bed awake due to insomnia
News
Cannabinoids Produce Worse Sleep Outcomes in Small Pilot Study
08/15/2025
Brionna Mendoza
A single dose of tetrahydrocannabinol/cannabidiol (THC/CBD) resulted in worse sleep for study participants with insomnia.
A single dose of tetrahydrocannabinol/cannabidiol (THC/CBD) resulted in worse sleep for study participants with insomnia.
A single dose of...
08/15/2025
Neurology
child sitting at a desk
News
Oseltamivir Reduces Risk of Serious Neuropsychiatric Events in Children During Influenza Episodes
08/13/2025
Maria Mantas
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was...
08/13/2025
Neurology

Alzheimer's Disease CME Series

Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology

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