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a hand points to a specific spot on a brain scan
News
07/13/2026
Maria Mantas
A nationwide cohort study found that prior use of P2Y12 inhibitors, either alone or combined with aspirin, was associated with more severe presentation and worse hospital outcomes in patients with spontaneous ICH.
A nationwide cohort study found that prior use of P2Y12 inhibitors, either alone or combined with aspirin, was associated with more severe presentation and worse hospital outcomes in patients with spontaneous ICH.
A nationwide cohort study found...
07/13/2026
Neurology
a researcher holds up a test tube of blood
News
07/06/2026
Maria Mantas
Plasma p-tau217/Aβ42 ratio accurately detected amyloid-PET positivity in veterans without traumatic brain injury (TBI), but accuracy declined significantly in those with prior TBI. 
Plasma p-tau217/Aβ42 ratio accurately detected amyloid-PET positivity in veterans without traumatic brain injury (TBI), but accuracy declined significantly in those with prior TBI. 
Plasma p-tau217/Aβ42 ratio...
07/06/2026
Neurology
doctor holds hands with an older woman patient sitting on the couch
News
06/29/2026
Maria Mantas
A longitudinal study reports that parity may modify the relationship between Alzheimer disease (AD) pathology and brain aging in cognitively unimpaired postmenopausal women.
A longitudinal study reports that parity may modify the relationship between Alzheimer disease (AD) pathology and brain aging in cognitively unimpaired postmenopausal women.
A longitudinal study reports...
06/29/2026
Neurology
an older woman sits on a couch looking out the window
Research Summary
06/17/2026
Maria Mantas
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
The presence of frontal release...
06/17/2026
Neurology
a doctor reviews brain scans
News
06/09/2026
Maria Mantas
A multicenter randomized clinical trial found that reperfusion-guided systolic blood pressure (BP) management after successful endovascular therapy improved 90-day functional outcomes compared with guideline-recommended care.
A multicenter randomized clinical trial found that reperfusion-guided systolic blood pressure (BP) management after successful endovascular therapy improved 90-day functional outcomes compared with guideline-recommended care.
A multicenter randomized...
06/09/2026
Neurology
a strand of RNA
News
06/01/2026
Maria Mantas
SKY-0515, an investigational oral RNA splicing modifier, reduced mutant huntingtin (mHTT) protein levels in blood by up to 69% and PMS1 mRNA by up to 26% in a phase 1/2 Huntington’s disease (HD) trial. 
SKY-0515, an investigational oral RNA splicing modifier, reduced mutant huntingtin (mHTT) protein levels in blood by up to 69% and PMS1 mRNA by up to 26% in a phase 1/2 Huntington’s disease (HD) trial. 
SKY-0515, an investigational...
06/01/2026
Neurology
a man lays in bed unable to sleep
News
05/26/2026
Maria Mantas
Disruptions in sleep-wake cycles may provide scalable early markers for dementia risk in older adults, according to cohort study findings.
Disruptions in sleep-wake cycles may provide scalable early markers for dementia risk in older adults, according to cohort study findings.
Disruptions in sleep-wake cycles...
05/26/2026
Neurology
a side profile of a human head, with the top portion appearing to be made of shattered, crumpled paper
News
05/11/2026
Maria Mantas
In a South Korea–based multicenter cohort, plasma phosphorylated tau217 (p-tau217), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) were associated with cognitive decline in early-onset Alzheimer disease (EOAD). 
In a South Korea–based multicenter cohort, plasma phosphorylated tau217 (p-tau217), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) were associated with cognitive decline in early-onset Alzheimer disease (EOAD). 
In a South Korea–based...
05/11/2026
Neurology
A doctor interacts with an elderly patient
News
05/04/2026
Maria Mantas
Findings from a large Aspirin in Reducing Events in the Elderly (ASPREE) cohort suggest cognitive changes could serve as early indicators of cardiovascular risk. 
Findings from a large Aspirin in Reducing Events in the Elderly (ASPREE) cohort suggest cognitive changes could serve as early indicators of cardiovascular risk. 
Findings from a large Aspirin in...
05/04/2026
Neurology
a clinician reviews brain scans in front of a laptop
News
04/24/2026
Maria Mantas
The addition of endovascular treatment (EVT) to best medical treatment (BMT) was associated with a higher likelihood of achieving good imaging outcomes compared with BMT alone in patients with a medium or distal vessel occlusion stroke.
The addition of endovascular treatment (EVT) to best medical treatment (BMT) was associated with a higher likelihood of achieving good imaging outcomes compared with BMT alone in patients with a medium or distal vessel occlusion stroke.
The addition of endovascular...
04/24/2026
Neurology