What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
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In a randomized clinical trial of 374 participants with focal epilepsy, adjunctive azetukalner demonstrated a rapid and durable reduction in seizure frequency during a 12-week treatment period.
In a randomized clinical trial of 374 participants with focal epilepsy, adjunctive azetukalner demonstrated a rapid and durable reduction in seizure frequency during a 12-week treatment period.
Psilocybin administration was associated with reductions in markers of systemic inflammation and mitochondrial stress among people with PD and mood dysfunction, according to a research letter published in JAMA Psychiatry.
Psilocybin administration was associated with reductions in markers of systemic inflammation and mitochondrial stress among people with PD and mood dysfunction, according to a research letter published in JAMA Psychiatry.
Delirium documented within 30 days of hospitalization was associated with a significantly higher risk of mild cognitive impairment and dementia, according to longitudinal cohort findings.
Delirium documented within 30 days of hospitalization was associated with a significantly higher risk of mild cognitive impairment and dementia, according to longitudinal cohort findings.
Several vascular risk factors, including smoking, hypertension, diabetes and prior stroke, were associated with LOE in older adults, according to pooled analysis findings.
Several vascular risk factors, including smoking, hypertension, diabetes and prior stroke, were associated with LOE in older adults, according to pooled analysis findings.
A meta-analysis of 38,418 participants across 18 countries or territories estimated 11.4 million new dementia cases globally in 2023, with annual incidence projected to reach 24.7 million by 2050.
A meta-analysis of 38,418 participants across 18 countries or territories estimated 11.4 million new dementia cases globally in 2023, with annual incidence projected to reach 24.7 million by 2050.
Treatment with ocrelizumab for up to 10 years was associated with sustained relapse control and minimal disability accrual in patients with relapsing MS, according to phase 3 findings.
Treatment with ocrelizumab for up to 10 years was associated with sustained relapse control and minimal disability accrual in patients with relapsing MS, according to phase 3 findings.
A nationwide cohort study found that prior use of P2Y12 inhibitors, either alone or combined with aspirin, was associated with more severe presentation and worse hospital outcomes in patients with spontaneous ICH.
A nationwide cohort study found that prior use of P2Y12 inhibitors, either alone or combined with aspirin, was associated with more severe presentation and worse hospital outcomes in patients with spontaneous ICH.
Plasma p-tau217/Aβ42 ratio accurately detected amyloid-PET positivity in veterans without traumatic brain injury (TBI), but accuracy declined significantly in those with prior TBI.
Plasma p-tau217/Aβ42 ratio accurately detected amyloid-PET positivity in veterans without traumatic brain injury (TBI), but accuracy declined significantly in those with prior TBI.
A longitudinal study reports that parity may modify the relationship between Alzheimer disease (AD) pathology and brain aging in cognitively unimpaired postmenopausal women.
A longitudinal study reports that parity may modify the relationship between Alzheimer disease (AD) pathology and brain aging in cognitively unimpaired postmenopausal women.
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
