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Chronic Wound Infection Topic Center

Systematic Review
Prevalence of Biofilm in Chronic Wounds: Systematic Review With Meta-Analysis
08/18/2025
Manuela de Mendonça Figueirêdo Coelho, PhD; Beatriz Moreira Alves Avelino, RN; Beatriz Alvez de Oliveira, MSN; Mariana Araújo Rios, RN; Fabiane do Amaral Gubert, PhD; Mariana Cavalcante Martins, PhD; Janaína Fonseca Victor Coutinho, PhD; Paula Sacha Frota Nogueira, PhD; Rachel Gabriel Bastos Barbosa, PhD; Viviane Mamede Vasconcelos Cavalcante, PhD
The authors of this article conducted a systematic review to determine how prevalent biofilm is in chronic wounds.
The authors of this article conducted a systematic review to determine how prevalent biofilm is in chronic wounds.
The authors of this article...
08/18/2025
Wounds
Case Report
Acid-Fast Bacilli Staining for Nonhealing Ulcers: A Case Report of Cutaneous Mycobacterium chelonae Infection
08/04/2025
Stephanie Behme, DPM; Shiwei Zhou, MD; Andrew Brown, DPM; Gary M. Rothenberg, DPM
A 64-year-old female presented with an enlarging ulceration that failed to respond to antibiotic therapy based on routine aerobic culture results. Acid-fast bacilli (AFB) cultures revealed a nontuberculous mycobacteria infection with...
A 64-year-old female presented with an enlarging ulceration that failed to respond to antibiotic therapy based on routine aerobic culture results. Acid-fast bacilli (AFB) cultures revealed a nontuberculous mycobacteria infection with...
A 64-year-old female presented...
08/04/2025
Wounds
Case Report
The “C-Swab” Test: A Technique for Identifying Bacteria in Sinus Tracts or Tunneled Wounds Utilizing a Cotton Swab and Bacterial Fluorescence Imaging
02/11/2025
Charles A. Andersen, MD; Katherine McLeod, CRNP, BSN, RN, CWCN
02/11/2025
Wounds
mina izadjoo phd
Videos
A Novel Therapeutic for Drug-resistant Candida auris: An Oral Abstract Presentation
06/26/2023
Mina Izadjoo
In this video, Dr. Izadjoo presents research that is focused on novel and cost-effective antimicrobials, including antifungals, ranging from small molecules to recombinant proteins.
In this video, Dr. Izadjoo presents research that is focused on novel and cost-effective antimicrobials, including antifungals, ranging from small molecules to recombinant proteins.
In this video, Dr. Izadjoo...
06/26/2023
Wounds
Case Report
Autologous Platelet-rich Plasma for the Treatment of Nonhealing Perineal Wounds: A Report of Two Cases
05/16/2023
Rong Wang; Zhen Zhao; Haiyan Wang; Shuang Liang; Lifeng Qin; Hairui Gao; Gang Zhao; Ying Li
Two patients with recalcitrant perineal wounds saw full wound closure within 2 weeks following treatment with platelet-rich plasma.
Two patients with recalcitrant perineal wounds saw full wound closure within 2 weeks following treatment with platelet-rich plasma.
Two patients with recalcitrant...
05/16/2023
Wounds
Consensus Statements
A Synthetic Hybrid-scale Fiber Matrix for Complex Surgical Wounds: Consensus Guidelines
05/15/2023
Paul J. Kim, DPM, MS, FACFAS; Luis G. Fernández; Marc R. Matthews, MD, FACS, MS
The authors present their consensus opinion on the use of a synthetic hybrid-scale fiber matrix for the management of open wounds.
The authors present their consensus opinion on the use of a synthetic hybrid-scale fiber matrix for the management of open wounds.
The authors present their...
05/15/2023
Wounds
Case Report
Case Report: Treatment of a Lower Leg Defect in the Course of Sarcoma With Microvascular Tissue
05/08/2023
Marek K. Dobke
A 29-year-old male who was undergoing chemotherapy for sarcoma presented with a nonhealing leg wound; 22 weeks after initiating treatment with a structural microvascular tissue allograft, the wound was fully closed.
A 29-year-old male who was undergoing chemotherapy for sarcoma presented with a nonhealing leg wound; 22 weeks after initiating treatment with a structural microvascular tissue allograft, the wound was fully closed.
A 29-year-old male who was...
05/08/2023
Wounds
Case Report
Therapeutic Taping to Offload Wound Margin Strain and as an Adjunct to Wound Closure: A Case Report
04/28/2023
Huang Xuecheng; Yang Junxing; Chen Haoxiong; Guo Fuming; Xu Qiliang
The authors detail a case in which elastic therapeutic tape was successfully used to close a surgical wound that had failed to heal almost 3 months after surgery.
The authors detail a case in which elastic therapeutic tape was successfully used to close a surgical wound that had failed to heal almost 3 months after surgery.
The authors detail a case in...
04/28/2023
Wounds
Review
Blue Light Therapy in the Management of Chronic Wounds: A Narrative Review of its Physiological Basis and Clinical Evidence
04/19/2023
Daniel Zhang; Gabrielle McMullin; Adriel Song Wei Leong
The authors conducted a review focused on the physiological impact of blue light on wound healing.
The authors conducted a review focused on the physiological impact of blue light on wound healing.
The authors conducted a review...
04/19/2023
Wounds
Case Report
Pyoderma Gangrenosum in a Patient With Dubowitz Syndrome: a New Comorbidity?
03/22/2023
Marco Romanelli; Cristian Fidanzi; Giammarco Granieri; Matteo Bevilacqua; Flavia Manzo Margiotta; Valentina Dini; Alessandra Michelucci; Giorgia Salvia
In this case report, the authors discuss a 50-year-old female who presented with necrotic, punched-out ulcers on her back.
In this case report, the authors discuss a 50-year-old female who presented with necrotic, punched-out ulcers on her back.
In this case report, the authors...
03/22/2023
Wounds
Case Report
Primary Cutaneous Mucormycosis of the Lower Extremity in a Male Patient With Diabetes
03/07/2023
James McKee; Arnold Paul C. Cua; Nicholas Chang; Valerie L. Marmolejo (Schade), DPM, MS, CTBS, MWC, FACFAS, FACFAOM
The authors of this case report present a 78-year-old male with primary cutaneous mucormycosis who was treated with surgical debridement and antibiotics.
The authors of this case report present a 78-year-old male with primary cutaneous mucormycosis who was treated with surgical debridement and antibiotics.
The authors of this case report...
03/07/2023
Wounds

Multimedia

mina izadjoo phd
Videos
A Novel Therapeutic for Drug-resistant Candida auris: An Oral Abstract Presentation
06/26/2023
Mina Izadjoo
In this video, Dr. Izadjoo presents research that is focused on novel and cost-effective antimicrobials, including antifungals, ranging from small molecules to recombinant proteins.
In this video, Dr. Izadjoo presents research that is focused on novel and cost-effective antimicrobials, including antifungals, ranging from small molecules to recombinant proteins.
In this video, Dr. Izadjoo...
06/26/2023
Wounds
Preview Image
Videos
Skin Substitutes for Treating Chronic Wounds: Q&A with the Agency for Healthcare Research and Quality
10/03/2022
This video features an interview with members of the ECRI Institute-Penn Medicine Evidence-Based Practice Center (ECRI) and the Agency for Healthcare Research and Quality regarding a systematic review of skin substitutes conducted by the ECRI...
This video features an interview with members of the ECRI Institute-Penn Medicine Evidence-Based Practice Center (ECRI) and the Agency for Healthcare Research and Quality regarding a systematic review of skin substitutes conducted by the ECRI...
This video features an interview...
10/03/2022
Wounds
WCLN logo
SAWC Insights
How Biopsies Clarify a Wound's Nature
05/27/2022
Robert J. Klein, DPM, FACFAS, CWS
In this video, Robert Klein, DPM, FACFAS, CWS, discusses why it's difficult to differentiate between malignant transformations of a chronic wound and the primary malignancy within the ulceration.
In this video, Robert Klein, DPM, FACFAS, CWS, discusses why it's difficult to differentiate between malignant transformations of a chronic wound and the primary malignancy within the ulceration.
In this video, Robert Klein,...
05/27/2022
Wounds
Preview Image
Videos
StrataGRT–A Breakthrough in Treatment on Chronic and Hard-to-Treat Wounds
01/15/2022
Matthew J. Regulski, DPM, ABMSP, CMET, FAPWH(c)
This video showcases the mechanisms of action and use of a topical gel in the scope of chronic, hard-to-treat wounds.
This video showcases the mechanisms of action and use of a topical gel in the scope of chronic, hard-to-treat wounds.
This video showcases the...
01/15/2022
Wounds
Preview Image
Expert Insights
The FDA's Take on Diabetic Foot Ulcer Treatments
12/01/2021
Kazem Kazempour
In this video, Kazem Kazempour , PhD, explains why it is so difficult for new wound healing therapies for DFUs to be approved by the FDA.
In this video, Kazem Kazempour , PhD, explains why it is so difficult for new wound healing therapies for DFUs to be approved by the FDA.
In this video, Kazem Kazempour ,...
12/01/2021
Wounds
Podcasts
The Use of an Advanced Fluorescence Imaging System to Target Wound Healing
08/23/2021
Listen to "The Use of an Advanced Fluorescence Imaging System to Target Wound Healing" on Spreaker.
Listen to "The Use of an Advanced Fluorescence Imaging System to Target Wound Healing" on Spreaker.
Listen to "The Use of an...
08/23/2021
Wounds
Podcasts
Wound Care Basics Every Clinician Needs to Know
05/20/2021
In day-to-day clinical practice, a wound care clinician will find themselves continually educating patients and other clinicians on the basic fundamentals of wound care.
In day-to-day clinical practice, a wound care clinician will find themselves continually educating patients and other clinicians on the basic fundamentals of wound care.
In day-to-day clinical practice,...
05/20/2021
Wounds
Podcasts
Procedural Pain in the Wound Center
04/27/2021
In this podcast, Laura Swoboda DNP, APNP, FNP-BC, CWOCN-AP, explores methods of pain control that are utilized by wound centers, which consist of pharmacologic and non-pharmacologic interventions.
In this podcast, Laura Swoboda DNP, APNP, FNP-BC, CWOCN-AP, explores methods of pain control that are utilized by wound centers, which consist of pharmacologic and non-pharmacologic interventions.
In this podcast, Laura Swoboda...
04/27/2021
Wounds
Podcasts
Pharmacology in Wound Care
02/10/2021
In this podcast, Janice M. Beitz, PhD, RN, CS, CNOR, CWOCN-AP, CRNP, APNC, ANEF, FNAP, FAAN, and Martha Kelso, RN, LNC, HBOT, discuss wound care with a focus on pharmacology. They delve into how different medications affect wounds and their...
In this podcast, Janice M. Beitz, PhD, RN, CS, CNOR, CWOCN-AP, CRNP, APNC, ANEF, FNAP, FAAN, and Martha Kelso, RN, LNC, HBOT, discuss wound care with a focus on pharmacology. They delve into how different medications affect wounds and their...
In this podcast, Janice M....
02/10/2021
Wounds
Podcasts
Evaluating and Treating Atypical Wounds
12/17/2020
Listen to "The Importance of Wound Measurements and How it Affects Treatment Plans" on Spreaker.
Listen to "The Importance of Wound Measurements and How it Affects Treatment Plans" on Spreaker.
Listen to "The Importance of...
12/17/2020
Wounds
Viewpoints
Is Mobile Wound Care Sustainable in Light of CTP/CAMPs Regulations? 
01/12/2026
Zwelithini Tunyiswa, BA; Ryan P. Dirks, PA-C
With tightening skin substitute reimbursement and increasing regulatory scrutiny, many are questioning whether mobile wound care remains sustainable. Drawing on real-world experience, this discussion reframes sustainability as a...
With tightening skin substitute reimbursement and increasing regulatory scrutiny, many are questioning whether mobile wound care remains sustainable. Drawing on real-world experience, this discussion reframes sustainability as a...
With tightening skin substitute...
01/12/2026
Wounds
Viewpoints
Focus on Compliance: Observations on the Impact of Skin Substitute Fraud, Waste, and Abuse
01/09/2026
Zwelithini Tunyiswa; Ryan P. Dirks, PA-C
In Part 2 of this interview series, Zwelithini Tunyiswa, BS, and Ryan Dirks, PA-C, of Open Wound Research confront the emotional and operational fallout of intensified fraud, waste, and abuse scrutiny in wound care—particularly as it relates...
In Part 2 of this interview series, Zwelithini Tunyiswa, BS, and Ryan Dirks, PA-C, of Open Wound Research confront the emotional and operational fallout of intensified fraud, waste, and abuse scrutiny in wound care—particularly as it relates...
In Part 2 of this...
01/09/2026
Wounds
Viewpoints
The Impact of CTP Changes on Provider Types
01/08/2026
Caroline E. Fife, MD, FAAFP, CWS, FUHM
Dr. Fife discusses the effects of CTP changes on hospital-based, mobile clinicians, skilled nursing and other settings, also touching on considerations with product handling.
Dr. Fife discusses the effects of CTP changes on hospital-based, mobile clinicians, skilled nursing and other settings, also touching on considerations with product handling.
Dr. Fife discusses the effects...
01/08/2026
Wounds
Viewpoints
Skin Substitutes' Influence on Wound Practice Sustainability: Historic and Research-Based Context
01/06/2026
Zwelithini Tunyiswa; Ryan P. Dirks, PA-C
In part 1 of this interview series, Zwelithini Tunyiswa, BS, and Ryan Dirks, PA-C, of Open Wound Research examine how mobile wound care has been reshaped by the rapid rise of cellular and acellular matrix products (CAMPs)/skin substitutes.
In part 1 of this interview series, Zwelithini Tunyiswa, BS, and Ryan Dirks, PA-C, of Open Wound Research examine how mobile wound care has been reshaped by the rapid rise of cellular and acellular matrix products (CAMPs)/skin substitutes.
In part 1 of this interview...
01/06/2026
Wounds
Matthew Regulski, DPM, FFPM, RCPS (Glasgow), DABMSP
Viewpoints
Cutting Costs, Raising Standards: The Case for Evidence-Based CTP Use
12/30/2025
Matthew J. Regulski, DPM, ABMSP, CMET, FAPWH(c)
CMS reimbursement reforms are reshaping the use of skin substitutes in wound care, phasing out high-cost, low-evidence products in favor of therapies backed by rigorous clinical data. New models like WISeR promote prior authorization to...
CMS reimbursement reforms are reshaping the use of skin substitutes in wound care, phasing out high-cost, low-evidence products in favor of therapies backed by rigorous clinical data. New models like WISeR promote prior authorization to...
CMS reimbursement reforms are...
12/30/2025
Wounds
Viewpoints
How CTP Changes Impact Providers, Patients, the Industry, and Policy
12/29/2025
Diane G. Weiss, CPC, CPB, CCP, CHRI
This speaker discusses how CTP changes affect various stakeholders, how prepared providers will be, whether regulatory efforts are fostering or stifling innovation, and what policy actions would ensure sustainable growth and fair competition...
This speaker discusses how CTP changes affect various stakeholders, how prepared providers will be, whether regulatory efforts are fostering or stifling innovation, and what policy actions would ensure sustainable growth and fair competition...
This speaker discusses how CTP...
12/29/2025
Wounds
Viewpoints
How New CTP Regulations Could Shape Access and Adoption of 351 Biologics
12/26/2025
Nikolai Sopko, MD, PhD; Ned Swanson, MD
As recent policy changes reshape the wound care and biologics landscape, the 351 pathway is emerging as one for innovation, rigor, and clinical confidence. While demanding in time and resources, these speakers share that they expect this...
As recent policy changes reshape the wound care and biologics landscape, the 351 pathway is emerging as one for innovation, rigor, and clinical confidence. While demanding in time and resources, these speakers share that they expect this...
As recent policy changes reshape...
12/26/2025
Wounds
Viewpoints
Policy Perspectives: Will Innovation Suffer Under CMS Skin Substitute Regulatory Changes?
12/24/2025
John Schroeder
The regulatory environment is "dramatically stifling our efforts to innovate," notes this speaker.
The regulatory environment is "dramatically stifling our efforts to innovate," notes this speaker.
The regulatory environment is...
12/24/2025
Wounds
Viewpoints
Building the Evidence for One Biologic in a Time of Regulatory Change: What's Next?
12/23/2025
Nikolai Sopko, MD, PhD; Ned Swanson, MD
The 351 regulatory pathway demands a highly structured, data-intensive clinical trial process that ensures alignment with the FDA and payers before the first patient is enrolled. One company is working to build rigorous pre-market evidence...
The 351 regulatory pathway demands a highly structured, data-intensive clinical trial process that ensures alignment with the FDA and payers before the first patient is enrolled. One company is working to build rigorous pre-market evidence...
The 351 regulatory pathway...
12/23/2025
Wounds
Viewpoints
CTP Evidence Standards Causing Industry Confusion
12/22/2025
John Schroeder
In this video, the speaker discusses "frustration and confusion" in the industry regarding clinical trials and notes a possible delay in product release.
In this video, the speaker discusses "frustration and confusion" in the industry regarding clinical trials and notes a possible delay in product release.
In this video, the speaker...
12/22/2025
Wounds

From the Publications

Case Report
Acid-Fast Bacilli Staining for Nonhealing Ulcers: A Case Report of Cutaneous Mycobacterium chelonae Infection
08/04/2025
Stephanie Behme, DPM; Shiwei Zhou, MD; Andrew Brown, DPM; Gary M. Rothenberg, DPM
A 64-year-old female presented with an enlarging ulceration that failed to respond to antibiotic therapy based on routine aerobic culture results. Acid-fast bacilli (AFB) cultures revealed a nontuberculous mycobacteria infection with...
A 64-year-old female presented with an enlarging ulceration that failed to respond to antibiotic therapy based on routine aerobic culture results. Acid-fast bacilli (AFB) cultures revealed a nontuberculous mycobacteria infection with...
A 64-year-old female presented...
08/04/2025
Wounds
Case Report
The “C-Swab” Test: A Technique for Identifying Bacteria in Sinus Tracts or Tunneled Wounds Utilizing a Cotton Swab and Bacterial Fluorescence Imaging
02/11/2025
Charles A. Andersen, MD; Katherine McLeod, CRNP, BSN, RN, CWCN
02/11/2025
Wounds
Case Report
Autologous Platelet-rich Plasma for the Treatment of Nonhealing Perineal Wounds: A Report of Two Cases
05/16/2023
Rong Wang; Zhen Zhao; Haiyan Wang; Shuang Liang; Lifeng Qin; Hairui Gao; Gang Zhao; Ying Li
Two patients with recalcitrant perineal wounds saw full wound closure within 2 weeks following treatment with platelet-rich plasma.
Two patients with recalcitrant perineal wounds saw full wound closure within 2 weeks following treatment with platelet-rich plasma.
Two patients with recalcitrant...
05/16/2023
Wounds
Case Report
Case Report: Treatment of a Lower Leg Defect in the Course of Sarcoma With Microvascular Tissue
05/08/2023
Marek K. Dobke
A 29-year-old male who was undergoing chemotherapy for sarcoma presented with a nonhealing leg wound; 22 weeks after initiating treatment with a structural microvascular tissue allograft, the wound was fully closed.
A 29-year-old male who was undergoing chemotherapy for sarcoma presented with a nonhealing leg wound; 22 weeks after initiating treatment with a structural microvascular tissue allograft, the wound was fully closed.
A 29-year-old male who was...
05/08/2023
Wounds
Case Report
Therapeutic Taping to Offload Wound Margin Strain and as an Adjunct to Wound Closure: A Case Report
04/28/2023
Huang Xuecheng; Yang Junxing; Chen Haoxiong; Guo Fuming; Xu Qiliang
The authors detail a case in which elastic therapeutic tape was successfully used to close a surgical wound that had failed to heal almost 3 months after surgery.
The authors detail a case in which elastic therapeutic tape was successfully used to close a surgical wound that had failed to heal almost 3 months after surgery.
The authors detail a case in...
04/28/2023
Wounds
Case Report
Pyoderma Gangrenosum in a Patient With Dubowitz Syndrome: a New Comorbidity?
03/22/2023
Marco Romanelli; Cristian Fidanzi; Giammarco Granieri; Matteo Bevilacqua; Flavia Manzo Margiotta; Valentina Dini; Alessandra Michelucci; Giorgia Salvia
In this case report, the authors discuss a 50-year-old female who presented with necrotic, punched-out ulcers on her back.
In this case report, the authors discuss a 50-year-old female who presented with necrotic, punched-out ulcers on her back.
In this case report, the authors...
03/22/2023
Wounds
Case Report
Primary Cutaneous Mucormycosis of the Lower Extremity in a Male Patient With Diabetes
03/07/2023
James McKee; Arnold Paul C. Cua; Nicholas Chang; Valerie L. Marmolejo (Schade), DPM, MS, CTBS, MWC, FACFAS, FACFAOM
The authors of this case report present a 78-year-old male with primary cutaneous mucormycosis who was treated with surgical debridement and antibiotics.
The authors of this case report present a 78-year-old male with primary cutaneous mucormycosis who was treated with surgical debridement and antibiotics.
The authors of this case report...
03/07/2023
Wounds
Case Series
Cicatrization of Oncological Wounds by Autologous Fibrin Biopolymer Dressing Treatment: A Case Series
02/01/2023
Chayane K.L. de Carvalho; Mauren Abreu de Souza; Michel M. Dalmedico; Beatriz Luci Fernandes, PhD
This series examines 3 cases in which an autologous biopolymer fibrin membrane was used to treat chronic oncological wounds that had displayed no sign of healing after more than 6 months of conventional treatment.
This series examines 3 cases in which an autologous biopolymer fibrin membrane was used to treat chronic oncological wounds that had displayed no sign of healing after more than 6 months of conventional treatment.
This series examines 3 cases in...
02/01/2023
Wounds
Case Series
Stepwise Surgical Technique Used to Treat Recalcitrant Pretibial Ulcerations: A Case Series
01/31/2023
Yi Arnold; Jeremy Perse; Deepali Darji, DPM
The authors report on 3 cases of chronic pretibial ulcers successfully treated with fenestration and the application of an antimicrobial fetal bovine acellular dermal matrix.
The authors report on 3 cases of chronic pretibial ulcers successfully treated with fenestration and the application of an antimicrobial fetal bovine acellular dermal matrix.
The authors report on 3 cases of...
01/31/2023
Wounds
Case Series
Protocol-driven Therapy for Lower Extremity Ulcers: A Case Series Supporting the Use of Porcine Intestine Extracellular Matrix
01/31/2023
Leydi Castro; Nelly Esperanza Jaimes; Luis Fernando Orduz; Diana Isabel Cáceres; Maria Andreina Pulido
01/31/2023
Wounds
Original Research
Evaluation of A Multilayer Antimicrobial Foam Dressing Indicated for Use on Surgical Incisions
12/18/2025
This article examines clinician experiences using a multilayer antimicrobial surgical incision dressing prophylactically in low-risk orthopedic and other surgical patients.
This article examines clinician experiences using a multilayer antimicrobial surgical incision dressing prophylactically in low-risk orthopedic and other surgical patients.
This article examines clinician...
12/18/2025
Wounds
Clinical Trial Protocol
A Multicenter Hybrid Platform Trial Evaluating Amniotic Tissue Grafts in Chronic Wounds: A Real-World Evidence Protocol for Diabetic Foot and Venous Leg Ulcers
12/11/2025
This trial protocol describes a pragmatic hybrid real-world evidence design assessing trilayer versus single-layer amniotic grafts for diabetic and venous leg ulcers.
This trial protocol describes a pragmatic hybrid real-world evidence design assessing trilayer versus single-layer amniotic grafts for diabetic and venous leg ulcers.
This trial protocol describes a...
12/11/2025
Wounds
Original Research
Nonhealing Wound Debridement Using a Finger-Mounted Debridement Tool
12/09/2025
This study assesses a novel finger-mounted debridement tool's usability, patient tolerability, and wound accessibility in managing chronic nonhealing wounds.
This study assesses a novel finger-mounted debridement tool's usability, patient tolerability, and wound accessibility in managing chronic nonhealing wounds.
This study assesses a novel...
12/09/2025
Wounds
Original Research
Patient-Reported Outcomes Favor Below-Knee Over Above-Knee Amputation in Patients With Nontraumatic Lower Extremity Wounds
12/04/2025
This study evaluates long-term pain, psychological well-being, resilience, and functional outcomes after above- versus below-knee amputation for chronic lower extremity wounds.
This study evaluates long-term pain, psychological well-being, resilience, and functional outcomes after above- versus below-knee amputation for chronic lower extremity wounds.
This study evaluates long-term...
12/04/2025
Wounds
Case Report
Challenges in Cadaveric Skin Graft Survival in Organ Transplant Recipients on Immunosuppressive Regimens: A Case Report
11/17/2025
Steven Tohmasi, MD, MPHS; Carolyn Tsung, BA; Ariana Naaseh, MD, MPHS; Jennifer Yu, MD, MPHS; John P. Kirby, MD; Lindsay M. Kranker
11/17/2025
Wounds
Original Research
Photobiomodulation in Wounds of Individuals With Diabetes: A Nonrandomized Pilot Study
11/17/2025
Beatriz Barbieri Bortolozo, MSc; Amanda Ramiro Gomes da Silva, MSc; Thais Paulino Prado, PhD; Bianca Campos Oliveira, PhD; Joseane Morari, PhD; Flávia Cristina Zanchetta, PhD; Eliana Pereira Araújo, PhD; Beatriz Guitton Renaud Baptista de Oliveira, PhD; Bruna Maiara Ferreira Barreto Pires, BSN, PhD; Priscila Peruzzo Apolinario, PhD; Maria Helena M. Lima, RN, PhD
This prospective study examined the impact of photobiomodulation on lower extremity wounds in patients with diabetes over the course of 12 weeks.
This prospective study examined the impact of photobiomodulation on lower extremity wounds in patients with diabetes over the course of 12 weeks.
This prospective study examined...
11/17/2025
Wounds
Original Research
Effect of Negative Pressure Wound Therapy with Instillation and Dwell Time on Health Care Utilization and Costs in South Africa
11/03/2025
Maeyane S. Moeng; Suleman Vadia, MBChB; Ashley W. Collinsworth, ScD, MPH; Siobhan Lookess, BSc, PGDip; Paolo Capelli
The authors of this article examine the utilization and cost impact of negative pressure wound therapy with instillation and dwell time in South Africa.
The authors of this article examine the utilization and cost impact of negative pressure wound therapy with instillation and dwell time in South Africa.
The authors of this article...
11/03/2025
Wounds
Original Research
Use of a Novel Debriding Agent Based on Collagenase and Hyaluronate Lyase to Enhance Angiogenesis, Stimulate Healing, and Reduce Pain in Chronic Cutaneous Wounds
10/31/2025
Jorge Adrián Garza-Cerna, MD, MSc; Gabriel Ángel Mecott-Rivera, MD, PhD; Yanko Castro-Govea, MD, PhD; José Juan Pérez-Trujillo, PhD; Roberto Montes de Oca-Luna, MD, PhD; Daniel Salas-Treviño, PhD; Valeria Kopytina, PhD; Jorge López Berroa, MD
This study evaluated the safety and efficacy of a novel debriding agent comprised of collagenases G and H, and hyaluronate lyase, in chronic wounds.
This study evaluated the safety and efficacy of a novel debriding agent comprised of collagenases G and H, and hyaluronate lyase, in chronic wounds.
This study evaluated the safety...
10/31/2025
Wounds
Case Report
Recurrent Martorell Ulcer in a Patient With Hypertension: A Therapeutic Success With Pentoxifylline
10/22/2025
This case describes pentoxifylline for Martorell ulcer when antihypertensive targets preclude standard therapies, highlighting vigilance and management in cerebrovascular comorbidity.
This case describes pentoxifylline for Martorell ulcer when antihypertensive targets preclude standard therapies, highlighting vigilance and management in cerebrovascular comorbidity.
This case describes...
10/22/2025
Wounds
Case Series
The Use of an Acellular Wound Matrix for Mohs Surgical Reconstruction: A Case Series
10/17/2025
Elizabeth A. Ansert, DPM; James F. Thornton, MD; Amy Du, BS; Alexandra Thornton, BS; Paul J. Kim, DPM
This retrospective review assesses acellular wound matrix reconstruction after Mohs surgery for foot lesions, emphasizing functional preservation and surgical considerations.
This retrospective review assesses acellular wound matrix reconstruction after Mohs surgery for foot lesions, emphasizing functional preservation and surgical considerations.
This retrospective review...
10/17/2025
Wounds

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