Videos

Global Treatment of Gastric/GEJ Cancer with Durvalumab Plus FLOT

Featuring Yelena Janjigian, MD

01/19/2024

At the 2024 ASCO Gastrointestinal Symposium, Yelena Janjigian, MD, Memorial Sloan Kettering Cancer Center, New York, New York, shared recent data from the MATTERHORN study, evaluating durvalumab plus 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy among patients with gastric or gastroesophageal junction cancer (GC/GEJC).

This subgroup analysis found the benefit to pathological complete response (pCR) of adding durvalumab to FLOT among patients with GC/GEJC was seen consistently across all geographic regions.

Source:

Janjigian YY, Al-Batran S, Wainberg ZA, et al. Pathological complete response (pCR) to 5-fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT) with or without durvalumab (D) in resectable gastric and gastroesophageal junction cancer (GC/GEJC): Subgroup analysis by region from the phase 3, randomized, double-blind MATTERHORN study. Presented at 2024 ASCO Gastrointestinal Cancer Symposium; January 18-20, 2024; San Francisco, California. Abstract LBA246

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